Full Text Journal Articles by
Author Juan C Duchesne

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Maintaining trauma center operational readiness during a pandemic.

Alexander C Cavalea, Robin McGoey, Rebecca W Schroll, Patrick R McGrew, Jonathan E Schoen, Lance E Stuke, Chrissy Guidry, Alan B Marr, Juan C Duchesne, John P Hunt,

The coronavirus disease 2019 (COVID-19) pandemic is a slow-moving global disaster with unique challenges for maintaining trauma center operations. University Medical Center New Orleans is the only level 1 trauma center in New Orleans, LA, which became an early hotspot for COVID-19. Intensive care unit surge capacity, addressing components including ... Read more >>

Am J Disaster Med (American journal of disaster medicine)
[2021, 16(1):25-34]

Cited: 0 times

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The efficacy of the use of presumptive antibiotics in tube thoracostomy in thoracic trauma-results of a meta-analysis.

Ahmed Elnahla, Kayla R Iuliucci, Eman Toraih, Juan C Duchesne, Ronald L Nichols, Emad Kandil,

<h4>Introduction</h4>The purpose of this study was to determine the impact of presumptive antibiotics, used in chest traumas requiring thoracostomies, in preventing infections such as empyema and pneumonia.<h4>Methods</h4>According to PRISMA guidelines, a systematic search of PubMed, Embase and Cochrane Library databases was conducted by two independent reviewers. Studies evaluating the role ... Read more >>

Am J Surg (American journal of surgery)
[2021, :]

Cited: 0 times

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Zero Preventable Deaths by 2020: Analysis of Prehospital and Emergency Department Deaths Following Penetrating Trauma Stratified by Anatomic Location.

August C Houghton, Jessica K Friedman, Alison A Smith, Eman A Toraih, Megan R Flanagan, Rebecca W Schroll, Chrissy Guidry, Patrick R McGrew, Samir M Fakhry, Juan C Duchesne,

<h4>Introduction</h4>Preventable deaths following trauma are high and unchanged over the last two decades. The objective of this study was to describe the location of death in patients with penetrating trauma, stratified by anatomic location of injury, in order to better tailor our approach to reducing preventable deaths from trauma.<h4>Methods</h4>This retrospective ... Read more >>

Am Surg (The American surgeon)
[2021, 87(5):784-789]

Cited: 0 times

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Analysis of Plasma Products for Cellular Contaminants: Comparing Standard Preparation Methods.

Richard R Rieske, Matthew E Kutcher, Jon P Audia, Kristen T Carter, Yann-Leei Lee, Yong B Tan, Mark N Gillespie, Gina C Capley, Danielle M Tatum, Alison A Smith, Juan C Duchesne, Jon D Simmons,

<h4>Background</h4>Recent reports suggest that component plasma products contain significant quantities of cellular contamination. We hypothesized that leukoreduction of whole blood before preparation of derived plasma is an effective method to prevent cellular contamination of stored plasma.<h4>Study design</h4>Samples of never-frozen liquid plasma prepared by standard methods (n = 25) were obtained from ... Read more >>

J Am Coll Surg (Journal of the American College of Surgeons)
[2020, 230(4):596-602]

Cited: 0 times

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Hypoxia/reoxygenation decreases endothelial glycocalyx via reactive oxygen species and calcium signaling in a cellular model for shock.

Olan Jackson-Weaver, Jessica K Friedman, Laura A Rodriguez, Marcus A Hoof, Robert H Drury, Jacob T Packer, Alison Smith, Chrissy Guidry, Juan C Duchesne,

BACKGROUND:Ischemia/reperfusion injury (IRI) has been shown to cause endothelial glycocalyx (EG) damage.Whether the hypoxic/ischemic insult or the oxidative and inflammatory stress of reperfusion plays a greater part in glycocalyx damage is not known. Furthermore, the mechanisms by which IRI causes EG damage have not been fully elucidated. The aims of ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, 87(5):1070-1076]

Cited: 3 times

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Plasma Transfusion Products and Contamination with Cellular and Associated Pro-Inflammatory Debris.

Yong B Tan, Richard R Rieske, Jon P Audia, Viktor M Pastukh, Gina C Capley, Mark N Gillespie, Alison A Smith, Danielle M Tatum, Juan C Duchesne, Matt E Kutcher, Jeffrey D Kerby, Jon D Simmons,

<h4>Background</h4>Stored plasma products are widely regarded as being functionally acellular, obviating the need for leukoreduction. We tested the hypothesis that donor plasma is contaminated by leukocytes and platelets, which, after frozen storage, would release cellular debris in quantities sufficient to elicit significant pro-inflammatory responses.<h4>Study design</h4>Samples of never-frozen liquid plasma from ... Read more >>

J Am Coll Surg (Journal of the American College of Surgeons)
[2019, 229(3):252-258]

Cited: 1 time

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Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma.

Jeremy W Cannon, Mansoor A Khan, Ali S Raja, Mitchell J Cohen, John J Como, Bryan A Cotton, Joseph J Dubose, Erin E Fox, Kenji Inaba, Carlos J Rodriguez, John B Holcomb, Juan C Duchesne,

<h4>Background</h4>The resuscitation of severely injured bleeding patients has evolved into a multi-modal strategy termed damage control resuscitation (DCR). This guideline evaluates several aspects of DCR including the role of massive transfusion (MT) protocols, the optimal target ratio of plasma (PLAS) and platelets (PLT) to red blood cells (RBC) during DCR, ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2017, 82(3):605-617]

Cited: 85 times

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Role of permissive hypotension, hypertonic resuscitation and the global increased permeability syndrome in patients with severe hemorrhage: adjuncts to damage control resuscitation to prevent intra-abdominal hypertension.

Juan C Duchesne, Lewis J Kaplan, Zsolt J Balogh, Manu L N G Malbrain,

Secondary intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are closely related to fluid resuscitation. IAH causes major deterioration of the cardiac function by affecting preload, contractility and afterload. The aim of this review is to discuss the different interactions between IAH, ACS and resuscitation, and to explore a new ... Read more >>

Anaesthesiol Intensive Ther (Anaesthesiology intensive therapy)
[2015, 47(2):143-155]

Cited: 13 times

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A multi-institutional analysis of prehospital tourniquet use.

Rebecca Schroll, Alison Smith, Norman E McSwain, John Myers, Kristin Rocchi, Kenji Inaba, Stefano Siboni, Gary A Vercruysse, Irada Ibrahim-Zada, Jason L Sperry, Christian Martin-Gill, Jeremy W Cannon, Seth R Holland, Martin A Schreiber, Diane Lape, Alexander L Eastman, Cari S Stebbins, Paula Ferrada, Jinfeng Han, Peter Meade, Juan C Duchesne,

<h4>Background</h4>Recent military studies demonstrated an association between prehospital tourniquet use and increased survival. The benefits of this prehospital intervention in a civilian population remain unclear. The aims of our study were to evaluate tourniquet use in the civilian population and to compare outcomes to previously published military experience. We hypothesized ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2015, 79(1):10-4; discussion 14]

Cited: 25 times

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Improvised tourniquets: Obsolete or obligatory?

Sarah K Stewart, Juan C Duchesne, Mansoor A Khan,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2015, 78(1):178-183]

Cited: 2 times

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Operation CeaseFire-New Orleans: an infectious disease model for addressing community recidivism from penetrating trauma.

Erin McVey, Juan C Duchesne, Siavash Sarlati, Michael O'Neal, Kelly Johnson, Jennifer Avegno,

<h4>Background</h4>CeaseFire, using an infectious disease approach, addresses violence by partnering hospital resources with the community by providing violence interruption and community-based services for an area roughly composed of a single city zip code (70113). Community-based violence interrupters start in the trauma center from the moment penetrating trauma occurs, through hospital ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2014, 77(1):123-128]

Cited: 3 times

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Impact of infusion rates of fresh frozen plasma and platelets during the first 180 minutes of resuscitation.

Eric R Simms, Dietric L Hennings, Adam Hauch, Julie Wascom, Tatyana E Fontenot, John P Hunt, Norman E McSwain, Peter C Meade, Leann Myers, Juan C Duchesne,

<h4>Background</h4>Whether high-ratio resuscitation (HRR) provides patients with survival advantage remains controversial. We hypothesized a direct correlation between HRR infusion rates in the first 180 minutes of resuscitation and survival.<h4>Study design</h4>This was a retrospective analysis of massively transfused trauma patients surviving more than 30 minutes and undergoing surgery at a level ... Read more >>

J Am Coll Surg (Journal of the American College of Surgeons)
[2014, 219(2):181-188]

Cited: 1 time

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To TQIP or not to TQIP? That is the question.

Jiselle Bock Heaney, Chrissy Guidry, Eric Simms, Jennifer Turney, Peter Meade, John P Hunt, Norman E McSwain, Juan C Duchesne,

The Trauma Quality Improvement Program (TQIP) reports a feasible mortality prediction model. We hypothesize that our institutional characteristics differ from TQIP aggregate data, questioning its applicability. We conducted a 2-year (2008 to 2009) retrospective analysis of all trauma activations at a Level 1 trauma center. Data were analyzed using TQIP ... Read more >>

Am Surg (The American surgeon)
[2014, 80(4):386-390]

Cited: 2 times

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Impact of hormonal protection in blunt and penetrating trauma: a retrospective analysis of the National Trauma Data Bank.

Snow Petersen, Eric R Simms, Chrissy Guidry, Juan C Duchesne,

Over the last decade, gender and age-related hormonal status of trauma patients have been increasingly recognized as outcome factors. In the present study, we examine a large cohort of trauma patients to better appraise the effects of gender and age on patient outcome after blunt and penetrating trauma. We hypothesize ... Read more >>

Am Surg (The American surgeon)
[2013, 79(9):944-951]

Cited: 1 time

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Initial assessment on the impact of crystalloids versus colloids during damage control resuscitation.

Chrissy Guidry, Elizabeth Gleeson, Eric R Simms, Lance Stuke, Peter Meade, Norman E McSwain, Juan C Duchesne,

<h4>Background</h4>High ratios of fresh frozen plasma:packed red blood cells in damage control resuscitation (DCR) are associated with increased survival. The impact of volume and type of resuscitative fluid used during high ratio transfusion has not been analyzed. We hypothesize a difference in outcomes based on the type and quantity of ... Read more >>

J Surg Res (The Journal of surgical research)
[2013, 185(1):294-299]

Cited: 6 times

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Mechanism of injury is not a predictor of trauma center admission.

Lance E Stuke, Juan C Duchesne, John P Hunt, Alan B Marr, Peter C Meade, Norman E McSwain,

Most trauma systems use mechanism of injury (MOI) as an indicator for trauma center transport, often overburdening the system as a result of significant overtriage. Before 2005 our trauma center accepted all MOI. After 2005 we accepted only those patients meeting anatomic and physiologic (A&P) triage criteria. Patients entered into ... Read more >>

Am Surg (The American surgeon)
[2013, 79(11):1149-1153]

Cited: 0 times

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Chasing 100%: the use of hypertonic saline to improve early, primary fascial closure after damage control laparotomy.

John A Harvin, Mark M Mims, Juan C Duchesne, Charles S Cox, Charles E Wade, John B Holcomb, Bryan A Cotton,

<h4>Background</h4>Failure to achieve fascial closure after damage control laparotomy (DCL) is associated with increased morbidity and long-term disability. In addition, early closure is associated with reduces infectious, wound, and pulmonary complications. We hypothesized that hypertonic saline (HTS), which attenuates resuscitation-induced intestinal edema in animals, would improve early primary fascial closure ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2013, 74(2):426-30; discussion 431-2]

Cited: 13 times

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When enough is enough: impact of packed red blood cells in massive transfusion outcomes.

Kira Long, Jiselle Bock Heaney, Eric R Simms, Norman E McSwain, Juan C Duchesne,

Massive transfusion protocol (MTP) with fresh-frozen plasma and packed red blood cells (PRBCs) in a 1:1 ratio is one of the most common resuscitative strategies used in patients with severe hemorrhage. There are no studies to date that examine the best postoperative hematocrit range as a marker for survival after ... Read more >>

Am Surg (The American surgeon)
[2013, 79(8):810-814]

Cited: 2 times

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Impact of inverse ratios on patients with exsanguinating vascular injuries: should more be the new paradigm?

Chrissy Guidry, Jeff DellaVope, Eric Simms, Jiselle B Heaney, Jodran Guice, Norman McSwain, Peter Meade, Juan C Duchesne,

<h4>Background</h4>Resuscitation strategies in patients with severe hemorrhage have evolved throughout the years. Optimal resuscitation ratios for civilian exsanguinating vascular injuries has not been determined. We hypothesize improved outcomes in patients with exsanguinating vascular injuries when an aggressive hemostatic resuscitation is used with an inverse ratio of fresh frozen plasma (FFP) ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2013, 74(2):403-9; discussion 409-10]

Cited: 4 times

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Damage control immunoregulation: is there a role for low-volume hypertonic saline resuscitation in patients managed with damage control surgery?

Juan C Duchesne, Eric Simms, Chrissy Guidry, Marquinn Duke, Esther Beeson, Norman E McSwain, Bryan Cotton,

Hypertonic saline (HTS) is beneficial in the treatment of head-injured patients as a result of its potent cytoprotective effects on various cell lines. We hypothesize that low-volume resuscitation with 3 per cent HTS, when used after damage control surgery (DCS), improves outcomes compared with standard resuscitation with isotonic crystalloid ... Read more >>

Am Surg (The American surgeon)
[2012, 78(9):962-968]

Cited: 7 times

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Low-volume resuscitation for severe intraoperative hemorrhage: a step in the right direction.

Juan C Duchesne, Chrissy Guidry, Jordan R H Hoffman, Timothy S Park, Jiselle Bock, Sarah Lawson, Peter Meade, Norman E McSwain,

The impact on outcomes resulting from crystalloids used with hemostatic close ratio resuscitation (HCRR) in intraoperative hemorrhage (IOH) has not been analyzed. We hypothesize a survival advantage in patients with IOH managed with a low-volume resuscitation (LVR) protocol during HCRR. A 4-year case-control study was conducted to determine the ... Read more >>

Am Surg (The American surgeon)
[2012, 78(9):936-941]

Cited: 4 times

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Lyophilized fibrinogen for hemorrhage after trauma.

Juan C Duchesne,

J Trauma (The Journal of trauma)
[2011, 70(5 Suppl):S50-2]

Cited: 0 times

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Damage control resuscitation: from emergency department to the operating room.

Juan C Duchesne, James M Barbeau, Tareq M Islam, Georgia Wahl, Patrick Greiffenstein, Norman E McSwain,

Damage control surgery emphasizes limited operations with control of bleeding and contamination. Traditional management centered upon correction of acidosis and hypotension with crystalloids. Damage control resuscitation (DCR) is permissive hypotension and early hemostatic resuscitation combined identified and corrects coagulopathy with fresh-frozen plasma (FFP), restricting use of crystalloids. We hypothesize a ... Read more >>

Am Surg (The American surgeon)
[2011, 77(2):201-206]

Cited: 42 times

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Damage control resuscitation: the new face of damage control.

Juan C Duchesne, Norman E McSwain, Bryan A Cotton, John P Hunt, Jeff Dellavolpe, Kelly Lafaro, Alan B Marr, Earnest A Gonzalez, Herb A Phelan, Tracy Bilski, Patrick Greiffenstein, James M Barbeau, Kelly V Rennie, Christopher C Baker, Karim Brohi, Donald H Jenkins, Michael Rotondo,

J Trauma (The Journal of trauma)
[2010, 69(4):976-990]

Cited: 97 times

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Linea alba fasciotomy: a novel alternative in trauma patients with secondary abdominal compartment syndrome.

Juan C Duchesne, Meghan P Howell, Calvin Eriksen, Georgia M Wahl, Kelly V Rennie, Paul E Hastings, Norman E McSwain, Manu L Malbrain,

Polytrauma patients needing aggressive resuscitation can develop intra-abdominal hypertension (IAH) with subsequent secondary abdominal compartment syndrome (SACS). After patients fail medical therapy, decompressive laparotomy is the surgical last resort. In patients with severe pancreatitis SACS, the use of linea alba fasciotomy (LAF) is an effective intervention to lower IAH without ... Read more >>

Am Surg (The American surgeon)
[2010, 76(3):312-316]

Cited: 1 time

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