Full Text Journal Articles by
Author Jozef Kesecioglu

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The Evolution of Toolkits and Bundles to Improve the Care of Sepsis Patients.

Greg S Martin, Sandra L Kane-Gill, Vinay Nadkarni, Lauren R Sorce, Lewis J Kaplan, Maurizio Cecconi, Elie Azoulay, Jean-Louis Teboul, Lui Forni, Jozef Kesecioglu,

Crit Care Med (Critical care medicine)
[2021, 49(11):1849-1850]

Cited: 0 times

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Surviving Sepsis Campaign: Research Opportunities for Infection and Blood Purification Therapies.

Ignacio Martin-Loeches, Mark E Nunnally, Judith Hellman, Ishaq Lat, Greg S Martin, Sameer Jog, Jozef Kesecioglu, Daniel De Backer, Craig M Coopersmith,

Patients with infection can develop sepsis, and their mortality can be high. An important aspect in the treatment of sepsis is adequate management of the infection.<h4>Data sources</h4>Using a modified Delphi approach, the Surviving Sepsis Campaign research committee recently published a series of 26 priorities for sepsis and septic shock.<h4>Study selection</h4>Task ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(9):e0511]

Cited: 0 times

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The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis.

Mark E Nunnally, Ricard Ferrer, Greg S Martin, Ignacio Martin-Loeches, Flavia R Machado, Daniel De Backer, Craig M Coopersmith, Clifford S Deutschman, ,

<h4>Objective</h4>To identify priorities for administrative, epidemiologic and diagnostic research in sepsis.<h4>Design</h4>As a follow-up to a previous consensus statement about sepsis research, members of the Surviving Sepsis Campaign Research Committee, representing the European Society of Intensive Care Medicine and the Society of Critical Care Medicine addressed six questions regarding care delivery, ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2021, 9(1):34]

Cited: 1 time

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Sharing ICU Patient Data Responsibly Under the Society of Critical Care Medicine/European Society of Intensive Care Medicine Joint Data Science Collaboration: The Amsterdam University Medical Centers Database (AmsterdamUMCdb) Example.

Patrick J Thoral, Jan M Peppink, Ronald H Driessen, Eric J G Sijbrands, Erwin J O Kompanje, Lewis Kaplan, Heatherlee Bailey, Jozef Kesecioglu, Maurizio Cecconi, Matthew Churpek, Gilles Clermont, Mihaela van der Schaar, Ari Ercole, Armand R J Girbes, Paul W G Elbers, ,

<h4>Objectives</h4>Critical care medicine is a natural environment for machine learning approaches to improve outcomes for critically ill patients as admissions to ICUs generate vast amounts of data. However, technical, legal, ethical, and privacy concerns have so far limited the critical care medicine community from making these data readily available. The ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(6):e563-e577]

Cited: 1 time

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The Surviving Sepsis Campaign: Research Priorities for Coronavirus Disease 2019 in Critical Illness.

Craig M Coopersmith, Massimo Antonelli, Seth R Bauer, Clifford S Deutschman, Laura E Evans, Ricard Ferrer, Judith Hellman, Sameer Jog, Jozef Kesecioglu, Niranjan Kissoon, Ignacio Martin-Loeches, Mark E Nunnally, Hallie C Prescott, Andrew Rhodes, Daniel Talmor, Pierre Tissieres, Daniel De Backer,

<h4>Objectives</h4>To identify research priorities in the management, pathophysiology, and host response of coronavirus disease 2019 in critically ill patients.<h4>Design</h4>The Surviving Sepsis Research Committee, a multiprofessional group of 17 international experts representing the European Society of Intensive Care Medicine and Society of Critical Care Medicine, was virtually convened during the coronavirus ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(4):598-622]

Cited: 6 times

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Diversity and inclusivity: the way to multidisciplinary intensive care medicine in Europe.

Maurizio Cecconi, Jozef Kesecioglu, Elie Azoulay, ,

Intensive Care Med (Intensive care medicine)
[2021, 47(5):598-601]

Cited: 0 times

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Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.

Yasser Sakr, Bruno François, Jordi Solé-Violan, Katarzyna Kotfis, Ulrich Jaschinski, Angel Estella, Marc Leone, Stephan M Jakob, Xavier Wittebole, Luis E Fontes, Miguel de Melo Gurgel, Thais Midega, Jean-Louis Vincent, V Marco Ranieri, ,

<h4>Background</h4>Mortality rates for patients with ARDS remain high. We assessed temporal changes in the epidemiology and management of ARDS patients requiring invasive mechanical ventilation in European ICUs. We also investigated the association between ventilatory settings and outcome in these patients.<h4>Methods</h4>This was a post hoc analysis of two cohorts of adult ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):87]

Cited: 2 times

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The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients.

Ishaq Lat, Craig M Coopersmith, Daniel De Backer, , , , , , , , , , , , , , , , , ,

<h4>Objective</h4>Expand upon the priorities of fluid resuscitation and vasopressor therapy research priorities identified by a group of experts assigned by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine.<h4>Data sources</h4>Original article, literature search.<h4>Study selection</h4>Several members of the original task force with expertise specific to the ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(4):623-635]

Cited: 3 times

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Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update.

Waleed Alhazzani, Laura Evans, Fayez Alshamsi, Morten Hylander Møller, Marlies Ostermann, Hallie C Prescott, Yaseen M Arabi, Mark Loeb, Michelle Ng Gong, Eddy Fan, Simon Oczkowski, Mitchell M Levy, Lennie Derde, Amy Dzierba, Bin Du, Flavia Machado, Hannah Wunsch, Mark Crowther, Maurizio Cecconi, Younsuck Koh, Lisa Burry, Daniel S Chertow, Wojciech Szczeklik, Emilie Belley-Cote, Massimiliano Greco, Malgorzata Bala, Ryan Zarychanski, Jozef Kesecioglu, Allison McGeer, Leonard Mermel, Manoj J Mammen, Sheila Nainan Myatra, Amy Arrington, Ruth Kleinpell, Giuseppe Citerio, Kimberley Lewis, Elizabeth Bridges, Ziad A Memish, Naomi Hammond, Frederick G Hayden, Muhammed Alshahrani, Zainab Al Duhailib, Greg S Martin, Lewis J Kaplan, Craig M Coopersmith, Massimo Antonelli, Andrew Rhodes,

<h4>Background</h4>The coronavirus disease 2019 pandemic continues to affect millions worldwide. Given the rapidly growing evidence base, we implemented a living guideline model to provide guidance on the management of patients with severe or critical coronavirus disease 2019 in the ICU.<h4>Methods</h4>The Surviving Sepsis Campaign Coronavirus Disease 2019 panel has expanded to ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(3):e219-e234]

Cited: 37 times

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ABCDEF Bundle and Supportive ICU Practices for Patients With Coronavirus Disease 2019 Infection: An International Point Prevalence Study.

Keibun Liu, Kensuke Nakamura, Hajime Katsukawa, Muhammed Elhadi, Peter Nydahl, Eugene Wesley Ely, Sapna R Kudchadkar, Kunihiko Takahashi, Shigeaki Inoue, Alan Kawarai Lefor, Jozef Kesecioglu, Osamu Nishida,

<h4>Objectives</h4>To investigate implementation of evidence-based and supportive cares in ICUs, such as the ABCDEF, nutrition therapy, and ICU diary, for patients with coronavirus disease 2019 infection in ICUs and their association with ICU clinical practice and setting.<h4>Design</h4>A worldwide, 2-day point prevalence study.<h4>Setting</h4>The study was carried out on June 3, 2020, ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(3):e0353]

Cited: 3 times

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The surviving sepsis campaign: fluid resuscitation and vasopressor therapy research priorities in adult patients.

Ishaq Lat, Craig M Coopersmith, Daniel De Backer, Craig M Coopersmith, ,

<h4>Objective</h4>To expand upon the priorities of fluid resuscitation and vasopressor therapy research priorities identified by a group of experts assigned by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine.<h4>Data sources</h4>Original paper and literature search.<h4>Study selection</h4>Several members of the original task force with expertise specific ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2021, 9(1):10]

Cited: 1 time

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How the COVID-19 pandemic will change the future of critical care.

Yaseen M Arabi, Elie Azoulay, Hasan M Al-Dorzi, Jason Phua, Jorge Salluh, Alexandra Binnie, Carol Hodgson, Derek C Angus, Maurizio Cecconi, Bin Du, Rob Fowler, Charles D Gomersall, Peter Horby, Nicole P Juffermans, Jozef Kesecioglu, Ruth M Kleinpell, Flavia R Machado, Greg S Martin, Geert Meyfroidt, Andrew Rhodes, Kathryn Rowan, Jean-François Timsit, Jean-Louis Vincent, Giuseppe Citerio,

Coronavirus disease 19 (COVID-19) has posed unprecedented healthcare system challenges, some of which will lead to transformative change. It is obvious to healthcare workers and policymakers alike that an effective critical care surge response must be nested within the overall care delivery model. The COVID-19 pandemic has highlighted key elements ... Read more >>

Intensive Care Med (Intensive care medicine)
[2021, 47(3):282-291]

Cited: 7 times

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Reducing medical device alarms by an order of magnitude: A human factors approach.

Erik Koomen, Craig S Webster, David Konrad, Johannes G van der Hoeven, Thomas Best, Jozef Kesecioglu, Diederik Ampj Gommers, Willem B de Vries, Teus H Kappen,

The intensive care unit (ICU) is one of the most technically advanced environments in healthcare, using a multitude of medical devices for drug administration, mechanical ventilation and patient monitoring. However, these technologies currently come with disadvantages, namely noise pollution, information overload and alarm fatigue-all caused by too many alarms. Individual ... Read more >>

Anaesth Intensive Care (Anaesthesia and intensive care)
[2021, 49(1):52-61]

Cited: 0 times

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ABCDEF Bundle and Supportive ICU Care Practices for patients with COVID-19 infection: An international point prevalence study ~The ISIIC Study~

Keibun Liu, Kensuke Nakamura, Hajime Katsukawa, Muhammed Elhadi, Peter Nydahl, Eugene Wesley Ely, Sapna Kudchadkar, Kunihiko Takahashi, Shigeaki Inoue, Alan Kawarai Lefor, Jozef Kesecioglu, Osamu Nishida,

<h4>Background: </h4> Although the number of patients with COVID-19 infection is increasing and concerns for their long-term disabilities are increasing, there is a lack of data about the delivery of the ABCDEF-bundle and supportive care in Intensive Care Units (ICUs). The aim of this study is to investigate the implementation ... Read more >>

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The surviving sepsis campaign: basic/translational science research priorities.

Clifford S Deutschman, Judith Hellman, Ricard Ferrer Roca, Daniel De Backer, Craig M Coopersmith, ,

<h4>Objectives</h4>Expound upon priorities for basic/translational science identified in a recent paper by a group of experts assigned by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine.<h4>Data sources</h4>Original paper, search of the literature.<h4>Study selection</h4>This study is selected by several members of the original task force ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2020, 8(1):31]

Cited: 2 times

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International variation in the management of severe COVID-19 patients.

Elie Azoulay, Jan de Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J Schaller, Manu Shankar-Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi,

<h4>Background</h4>There is little evidence to support the management of severe COVID-19 patients.<h4>Methods</h4>To document this variation in practices, we performed an online survey (April 30-May 25, 2020) on behalf of the European Society of Intensive Care Medicine (ESICM). A case vignette was sent to ESICM members. Questions investigated practices for a ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):486]

Cited: 9 times

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Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak.

Elie Azoulay, Jan De Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J Schaller, Manu Shankar Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi, ,

<h4>Background</h4>The COVID-19 pandemic has resulted in an unprecedented healthcare crisis with a high prevalence of psychological distress in healthcare providers. We sought to document the prevalence of burnout syndrome amongst intensivists facing the COVID-19 outbreak.<h4>Methods</h4>Cross-sectional survey among intensivists part of the European Society of Intensive Care Medicine. Symptoms of severe burnout, ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2020, 10(1):110]

Cited: 35 times

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Beta-2-glycoprotein I as a biomarker for sepsis in critically ill patients in the intensive care unit: a prospective cohort study.

Irene T Schrijver, Hans Kemperman, Mark Roest, Jozef Kesecioglu, Dylan W de Lange,

Crit Care (Critical care (London, England))
[2020, 24(1):341]

Cited: 2 times

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Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

Maaike A Sikma, Erik M Van Maarseveen, Claudine C Hunault, Javier M Moreno, Ed A Van de Graaf, Johannes H Kirkels, Marianne C Verhaar, Jan C Grutters, Jozef Kesecioglu, Dylan W De Lange, Alwin D R Huitema,

<h4>Background and objective</h4>Therapeutic drug monitoring of tacrolimus whole-blood concentrations is standard care in thoracic organ transplantation. Nevertheless, toxicity may appear with alleged therapeutic concentrations possibly related to variability in unbound concentrations. However, pharmacokinetic data on unbound concentrations are not available. The objective of this study was to quantify the pharmacokinetics ... Read more >>

Clin Pharmacokinet (Clinical pharmacokinetics)
[2020, 59(6):771-780]

Cited: 2 times

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The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database.

Jean-Louis Vincent, Andrew Ferguson, Peter Pickkers, Stephan M Jakob, Ulrich Jaschinski, Ghaleb A Almekhlafi, Marc Leone, Majid Mokhtari, Luis E Fontes, Philippe R Bauer, Yasser Sakr, ,

<h4>Background</h4>Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):171]

Cited: 2 times

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High Variability of Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

Maaike A Sikma, Claudine C Hunault, Erik M Van Maarseveen, Alwin D R Huitema, Ed A Van de Graaf, Johannes H Kirkels, Marianne C Verhaar, Jan C Grutters, Jozef Kesecioglu, Dylan W De Lange,

<h4>Background and objective</h4>Oral tacrolimus is initiated perioperatively in heart and lung transplantation patients. There have been few studies on oral tacrolimus pharmacokinetics early post-transplantation, even though tacrolimus-related toxicity may occur early, potentially leading to morbidity and mortality. Therefore, we aimed to study the pharmacokinetics of oral tacrolimus in thoracic organ ... Read more >>

Eur J Drug Metab Pharmacokinet (European journal of drug metabolism and pharmacokinetics)
[2020, 45(1):123-134]

Cited: 2 times

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Imagine…(a common language for ICU data inquiry and analysis).

Lewis J Kaplan, Maurizio Cecconi, Heatherlee Bailey, Jozef Kesecioglu,

Intensive Care Med (Intensive care medicine)
[2020, 46(3):531-533]

Cited: 0 times

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Imagin… (A Common Language for ICU Data Inquiry and Analysis).

Lewis J Kaplan, Maurizio Cecconi, Heatherlee Bailey, Jozef Kesecioglu,

Crit Care Med (Critical care medicine)
[2020, 48(3):273-275]

Cited: 1 time

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Agreement With Consensus Statements on End-of-Life Care: A Description of Variability at the Level of the Provider, Hospital, and Country.

Ann C Long, Lyndia C Brumback, J Randall Curtis, Alexander Avidan, Mario Baras, Edoardo De Robertis, Linda Efferen, Ruth A Engelberg, Erin K Kross, Andrej Michalsen, Richard A Mularski, Charles L Sprung, ,

<h4>Objectives</h4>To develop an enhanced understanding of factors that influence providers' views about end-of-life care, we examined the contributions of provider, hospital, and country to variability in agreement with consensus statements about end-of-life care.<h4>Design and setting</h4>Data were drawn from a survey of providers' views on principles of end-of-life care obtained during ... Read more >>

Crit Care Med (Critical care medicine)
[2019, 47(10):1396-1401]

Cited: 5 times

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Interprofessional Shared Decision-Making in the ICU: A Systematic Review and Recommendations From an Expert Panel.

Andrej Michalsen, Ann C Long, Freda DeKeyser Ganz, Douglas B White, Hanne I Jensen, Victoria Metaxa, Christiane S Hartog, Jos M Latour, Robert D Truog, Jozef Kesecioglu, Anna R Mahn, J Randall Curtis,

<h4>Objectives</h4>There is growing recognition that high-quality care for patients and families in the ICU requires exemplary interprofessional collaboration and communication. One important aspect is how the ICU team makes complex decisions. However, no recommendations have been published on interprofessional shared decision-making. The aim of this project is to use systematic ... Read more >>

Crit Care Med (Critical care medicine)
[2019, 47(9):1258-1266]

Cited: 10 times

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