Full Text Journal Articles by
Author Joseph Ting

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Mortality and significant neurosensory impairment in preterm infants: an international comparison.

Marie Chevallier, Thierry Debillon, Brian A Darlow, Anne R Synnes, Véronique Pierrat, Elizabeth Hurrion, Junmin Yang, Anne Ego, Pierre Yves Ancel, Kei Lui, Prakeshkumar S Shah, Thuy Mai Luu, , , , ,

<h4>Objective</h4>To compare mortality and rates of significant neurosensory impairment (sNSI) at 18-36 months' corrected age in infants born extremely preterm across three international cohorts.<h4>Design</h4>Retrospective analysis of prospectively collected neonatal and follow-up data.<h4>Setting</h4>Three population-based observational cohort studies: the Australian and New Zealand Neonatal Network (ANZNN), the Canadian Neonatal and Follow-up Networks ... Read more >>

Arch Dis Child Fetal Neonatal Ed (Archives of disease in childhood. Fetal and neonatal edition)
[2021, :]

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Diagnostic reasoning is associated with lower physician satisfaction with patient communication.

Daniel Rab Schweitzer, Joseph Ting, Bill von Hippel,

<h4>Objectives</h4>The objective of the study was to examine the quality of communication across the different medical specialties. Prior research suggests that the quality of communication between doctors and patients influences the quality of medical care and adherence to treatment regimens, but little is known about factors that contribute to successful ... Read more >>

Intern Med J (Internal medicine journal)
[2021, :]

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Variability in antimicrobial use among infants born at <33 weeks gestational age.

Joseph Y Ting, Ashley Roberts, Ayman Abou Mehrem, Faiza Khurshid, Christine Drolet, Luis Monterrosa, Eugene W Yoon, Prakesh S Shah, ,

Excessive antimicrobial use is associated with adverse neonatal outcomes. In our cohort of 27,163 infants born at <33 weeks gestational age, the first week after birth accounted for the highest rates of antimicrobial use, and variability across sites persisted after adjustment for patient characteristics correlated with illness severity. ... Read more >>

Infect Control Hosp Epidemiol (Infection control and hospital epidemiology)
[2021, :1-5]

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Delayed cord clamping in small for gestational age preterm infants.

Beth Ellen Brown, Prakesh S Shah, Jehier K Afifi, Rebecca L Sherlock, Mohammad A Adie, Luis A Monterrosa, Joan M Crane, Xiang Y Ye, Walid I El-Naggar, , ,

<h4>Background</h4>Infants with restricted growth for age are frequently exposed to insufficient placental circulation and are more likely to develop postnatal complications. Delayed cord clamping at birth for these infants requires further exploration.<h4>Objective</h4>This study aimed to compare the short-term neonatal outcomes of delayed cord clamping with that of early cord clamping ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2021, :]

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Strategies and interventions for improving safety culture in Australian Emergency Departments: A modified Delphi study.

Muhammad Ahmed Alshyyab, Gerard FitzGerald, Rania Ali Albsoul, Joseph Ting, Frances B Kinnear, Erika Borkoles,

<h4>Background</h4>Patient safety and safety culture are critical for quality healthcare delivery in general and in Emergency Departments (EDs) in particular. The aim of this study is to identify strategies that may contribute to the improvement and maintenance of patient safety culture and which are considered most feasible in the ED ... Read more >>

Int J Health Plann Manage (The International journal of health planning and management)
[2021, :]

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A Survey on Variation in Diagnosis and Treatment of Chorioamnionitis in Tertiary Centres in Canada.

Clara Charpentier, Sarah McDonald, Chealsea Elwood, Joseph Ting, Adriana Grigoriu, Christy Pylypjuk, Mark Yudin, Julianne Van Schalkwyk, Isabelle Boucoiran,

<h4>Objective</h4>Clinical detection and management of chorioamnionitis is challenging given the gold-standard for diagnosis remains placental pathology, the results of which are only available after delivery. Moreover, recommended diagnostic criteria for clinical chorioamnionitis have evolved over time. The goal of this study was to describe trends and differences in chorioamnionitis diagnostic ... Read more >>

J Obstet Gynaecol Can (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC)
[2021, :]

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Neurodevelopmental outcomes of singleton large for gestational age infants <29 weeks' gestation: a retrospective cohort study.

Deepika Rustogi, Anne Synnes, Belal Alshaikh, Shabih Hasan, Christine Drolet, Edith Masse, Prashanth Murthy, Prakesh S Shah, Kamran Yusuf, ,

<h4>Objective</h4>To compare neurodevelopmental outcomes of large and appropriate for gestational age (LGA, AGA) infants <29 weeks' gestation at 18-24 months of corrected age.<h4>Study design</h4>Retrospective cohort study using the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network databases. Primary outcome was a composite of death or significant neurodevelopmental impairment (NDI), defined ... Read more >>

J Perinatol (Journal of perinatology : official journal of the California Perinatal Association)
[2021, 41(6):1313-1321]

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Family integrated care: very preterm neurodevelopmental outcomes at 18 months.

Anne R Synnes, Julie Petrie, Ruth E Grunau, Paige Church, Edmond Kelly, Diane Moddemann, Xiang Ye, Shoo K Lee, Karel O'Brien, , ,

<h4>Objective</h4>To examine whether the family integrated care (FICare) programme, a multifaceted approach which enables parents to be engaged as primary caregivers in the neonatal intensive care unit, impacts infant neurodevelopment and growth at 18 months' corrected age.<h4>Design/methods</h4>Prospective cohort study of infants born <29 weeks' gestational age (GA) who participated in ... Read more >>

Arch Dis Child Fetal Neonatal Ed (Archives of disease in childhood. Fetal and neonatal edition)
[2021, :]

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Quantifying Proximal Collecting Tubule Deficiency in Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Fetopathy.

Jessica Saunders, Allison Marie Callejas Salgado, Joseph Y Ting, Cherry Mammen, Jefferson Terry, Jonathan W Bush,

<h4>Introduction</h4>Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers (AAs) are used for several indications, with cessation recommended in pregnancy due to toxic effects. AA fetopathy phenotype is similar to renal tubular dysgenesis including reduced proximal convoluted tubules (PCTs). Our study aimed to quantify the reduction of PCTs in fetuses and ... Read more >>

Pediatr Dev Pathol (Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society)
[2021, 24(5):438-444]

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Factors Associated with Umbilical Venous Catheter Malposition in Newborns: A Tertiary Center Experience.

Sasivimon Soonsawad, Emily A Kieran, Joseph Y Ting, Esther AlonsoPrieto, Julia K Panczuk,

<h4>Objective</h4> Umbilical venous catheters (UVC) are widely used in neonatal intensive care (NICU). Noncentral catheter position is known to be associated with multiple adverse complications; however, risk factors for catheter malposition are unclear. This work aimed to identify clinical risk factors and complications associated with UVC malposition in neonates admitted in ... Read more >>

Am J Perinatol (American journal of perinatology)
[2021, :]

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Association of timing of birth with mortality among preterm infants born in Canada.

Angelo Rizzolo, Prakesh S Shah, Valerie Bertelle, Hala Makary, Xiang Y Ye, Haim A Abenhaim, Bruno Piedboeuf, Marc Beltempo, ,

<h4>Objective</h4>To assess the association between time of birth and mortality among preterm infants.<h4>Study design</h4>Population-based study of infants born 22-36 weeks gestation (GA) in Canada from 2010 to 2015 (n = 173 789). Multivariable logistic regression models assessed associations between timing of birth and mortality.<h4>Result</h4>Among infants 22-27 weeks GA, evening birth was associated ... Read more >>

J Perinatol (Journal of perinatology : official journal of the California Perinatal Association)
[2021, :]

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Rates and Determinants of Mother's Own Milk Feeding in Infants Born Very Preterm.

Dinesh Dharel, Nalini Singhal, Christel Wood, Zenon Cieslak, Fabiana Bacchini, Prakesh S Shah, Xiang Y Ye, Belal Alshaikh, ,

<h4>Objectives</h4>To examine rates and determinants of mother's own milk (MOM) feeding at hospital discharge in a cohort of infants born very preterm within the Canadian Neonatal Network (CNN).<h4>Study design</h4>This was a population-based cohort study of infants born at <33 weeks of gestation and admitted to neonatal intensive care units (NICUs) participating ... Read more >>

J Pediatr (The Journal of pediatrics)
[2021, 236:21-27.e4]

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Relative effectiveness and safety of pharmacotherapeutic agents for patent ductus arteriosus (PDA) in preterm infants: a protocol for a multicentre comparative effectiveness study (CANRxPDA).

Souvik Mitra, Amish Jain, Joseph Y Ting, Nadya Ben Fadel, Christine Drolet, Ayman Abou Mehrem, Amuchou Soraisham, Bonny Jasani, Deepak Louis, Anie Lapointe, Jon Dorling, Faiza Khurshid, Abbas Hyderi, Kumar Kumaran, Jaya Bodani, Dany Weisz, Ruben Alvaro, Mohammed Adie, Miroslav Stavel, Alyssa Morin, Soume Bhattacharya, Jaideep Kanungo, Rody Canning, Xiang Y Ye, Tara Hatfield, Courtney E Gardner, Prakesh Shah,

<h4>Introduction</h4>Patent ductus arteriosus (PDA) is the most common cardiovascular problem that develops in preterm infants and evidence regarding the best treatment approach is lacking. Currently available medical options to treat a PDA include indomethacin, ibuprofen or acetaminophen. Wide variation exists in PDA treatment practices across Canada. In view of this ... Read more >>

BMJ Open (BMJ open)
[2021, 11(5):e050682]

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Hospital medical emergency teams and fears of COVID-19: the double-edged sword of pre-alerts.

Joseph Ting,

Intern Med J (Internal medicine journal)
[2021, 51(4):471-472]

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Multicentre prospective observational study exploring the predictive value of functional echocardiographic indices for early identification of preterm neonates at risk of developing chronic pulmonary hypertension secondary to chronic neonatal lung disease.

Laura Thomas, Michelle Baczynski, Poorva Deshpande, Ashraf Kharrat, Sébastien Joye, Faith Zhu, Daniel Ibarra-Rios, Prakesh S Shah, Luc Mertens, Robert P Jankov, Xiang Y Ye, Elaine Neary, Joseph Ting, Michael Castaldo, Philip Levy, Aisling Smith, Afif F El-Khuffash, Regan E Giesinger, Patrick J McNamara, Dany E Weisz, Amish Jain,

<h4>Introduction</h4>Although chronic pulmonary hypertension (cPH) secondary to chronic neonatal lung disease is associated with increased mortality and respiratory and neurodevelopmental morbidities, late diagnosis (typically ≥36 weeks postmenstrual age, PMA) and the use of qualitative echocardiographic diagnostic criterion (flat interventricular septum in systole) remain significant limitations in clinical care. Our objective ... Read more >>

BMJ Open (BMJ open)
[2021, 11(3):e044924]

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Neurodevelopmental outcomes of preterm infants conceived by assisted reproductive technology.

Smita Roychoudhury, Abhay Lodha, Anne Synnes, Ayman Abou Mehrem, Roderick Canning, Rudaina Banihani, Marc Beltempo, Katherine Theriault, Junmin Yang, Prakesh S Shah, Amuchou S Soraisham, , , ,

<h4>Background</h4>There have been concerns about the development of children conceived through assisted reproductive technology. Despite multiple studies investigating the outcomes of assisted conception, data focusing specifically on the neurodevelopmental outcomes of infants conceived through assisted reproductive technology and born preterm are limited.<h4>Objective</h4>This study aimed to evaluate and compare the neurodevelopmental ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2021, 225(3):276.e1-276.e9]

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Gestational Age-Dependent Variations in Effects of Prophylactic Indomethacin on Brain Injury and Intestinal Injury.

Mosarrat Qureshi, Prakesh S Shah, Dalal Abdelgadir, Xiang Y Ye, Jehier Afifi, Ryan Yuen, Sara Calderon Crossman, Barbara Taylor, Khorshid Mohammad, Bruno Piedboeuf, Khalid Aziz, ,

<h4>Objective</h4>To evaluate the impact of prophylactic indomethacin on early death (<10 days after birth) or severe neurologic injury and on early death or spontaneous intestinal perforation by completed weeks of gestational age in neonates born <29 weeks of gestation.<h4>Study design</h4>This was a multicenter, retrospective cohort study of neonates (n = 12 515) born at ... Read more >>

J Pediatr (The Journal of pediatrics)
[2021, 235:26-33.e2]

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Variations in Neonatal Length of Stay of Babies Born Extremely Preterm: An International Comparison Between iNeo Networks.

Sarah E Seaton, Elizabeth S Draper, Mark Adams, Satoshi Kusuda, Stellan Håkansson, Kjell Helenius, Brian Reichman, Liisa Lehtonen, Dirk Bassler, Shoo K Lee, Maximo Vento, Brian A Darlow, Franca Rusconi, Marc Beltempo, Tetsuya Isayama, Kei Lui, Mikael Norman, Junmin Yang, Prakesh S Shah, Neena Modi, , , , , , , ,

<h4>Objective</h4>To compare length of stay (LOS) in neonatal care for babies born extremely preterm admitted to networks participating in the International Network for Evaluating Outcomes of Neonates (iNeo).<h4>Study design</h4>Data were extracted for babies admitted from 2014 to 2016 and born at 24 to 28 weeks of gestational age (n = 28 204). Median ... Read more >>

J Pediatr (The Journal of pediatrics)
[2021, 233:26-32.e6]

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Association of Co-Exposure of Antenatal Steroid and Prophylactic Indomethacin with Spontaneous Intestinal Perforation.

Hemasree Kandraju, Jaideep Kanungo, Kyong-Soon Lee, Sibasis Daspal, Mohammad Amin Adie, Jon Dorling, Xiang Y Ye, Shoo K Lee, Prakesh S Shah, , ,

<h4>Objective</h4>To evaluate the association of a combined exposure to antenatal steroids and prophylactic indomethacin with the outcome of spontaneous intestinal perforation (SIP) among neonates born at <26 weeks of gestation or <750 g birth weight.<h4>Study design</h4>We conducted a retrospective study of preterm infants admitted to Canadian Neonatal Network units between 2010 and ... Read more >>

J Pediatr (The Journal of pediatrics)
[2021, 235:34-41.e1]

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Development of a national neonatal intensive care unit-specific antimicrobial stewardship programme in Canada: protocol for a cohort study.

Joseph Y Ting, Ashley Roberts, Peter Tilley, Joan L Robinson, Michael S Dunn, Vanessa Paquette, Kyong-Soon Lee, Vibhuti Shah, Eugene Yoon, Lindsay L Richter, Abhay Lodha, Sandesh Shivananda, Nisha Thampi, Julie Autmizguine, Prakesh S Shah, ,

<h4>Introduction</h4>Early empiric treatment with broad-spectrum antimicrobials is common in neonatal intensive care units (NICU) due to the non-specific clinical presentation of infection. However, excessive and inappropriate antimicrobial use can lead to the emergence of drug-resistant organisms and adverse neonatal outcomes. This study aims to develop and implement a nationwide NICU-specific ... Read more >>

BMJ Open (BMJ open)
[2020, 10(12):e043403]

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Acute kidney injury among preterm infants receiving non-steroidal anti-inflammatory drugs for patent ductus arteriosus

Joseph Ting, Kate McDougal, Alanna De Mello, Eddie Kwan, Cherry Mammen,

<h4>Background: </h4> Nonsteroidal anti-inflammatory drugs (NSAID) are a frequently prescribed class of medication in the neonatal intensive care unit (NICU). Hospitalized patients receiving NSAID therapy are at an increased risk of acute kidney injury (AKI). Our primary objective was to reveal AKI epidemiology in NSAID-exposed premature infants admitted to the ... Read more >>

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Mode of delivery and neonatal outcomes in extremely preterm Vertex/nonVertex twins.

Liran Hiersch, Prakesh S Shah, Faiza Khurshid, Edith Masse, Kellie Murphy, Sarah D McDonald, George Carson, Jon Barrett, Nir Melamed, ,

<h4>Background</h4>One of the controversies in the management of twin gestations relates to mode of delivery, especially when the second twin is in a nonvertex presentation (Vertex/nonVertex pairs) and birth is imminent at extremely low gestation.<h4>Objective</h4>We hypothesized that, for Vertex/nonVertex twins born before 28 weeks' gestation, cesarean delivery would be associated ... Read more >>

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2021, 224(6):613.e1-613.e10]

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Duration of and trends in respiratory support among extremely preterm infants.

Dany E Weisz, Eugene Yoon, Michael Dunn, Julie Emberley, Amit Mukerji, Brooke Read, Prakeshkumar S Shah, ,

<h4>Objective</h4>To evaluate annual trends in the administration and duration of respiratory support among preterm infants.<h4>Design</h4>Retrospective cohort study.<h4>Setting</h4>Tertiary neonatal intensive care units in the Canadian Neonatal Network.<h4>Patients</h4>8881 extremely preterm infants born from 2010 to 2017 treated with endotracheal and/or non-invasive positive pressure support (PPS).<h4>Main outcome measures</h4>Competing risks methods were used to ... Read more >>

Arch Dis Child Fetal Neonatal Ed (Archives of disease in childhood. Fetal and neonatal edition)
[2021, 106(3):286-291]

Cited: 1 time

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Hospital in the air: Royal Flying Doctor Service retrievals and challenges before, during and after, Australia's COVID-19 lockdown in 2020.

Joseph Ting,

Intern Med J (Internal medicine journal)
[2020, 50(12):1449-1451]

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Benefit of antenatal corticosteroids by year of birth among preterm infants in Canada during 2003-2017: a population-based cohort study.

N Melamed, K Murphy, J Barrett, E Asztalos, S D McDonald, E W Yoon, P S Shah, ,

<h4>Objective</h4>To evaluate the changes in the associations of antenatal corticosteroids (ACS) with neonatal mortality and severe neurological injury over time (2003-17).<h4>Design</h4>National, population-representative, retrospective cohort study.<h4>Setting</h4>Level III neonatal intensive care units participating in the Canadian Neonatal Network.<h4>Population</h4>All infants born at 23<sup>0/7</sup> -33<sup>6/7</sup> weeks of gestation (n = 43 456).<h4>Methods</h4>We estimated the associations between exposure ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2021, 128(3):521-531]

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