Full Text Journal Articles by
Author Jonathon Olsburgh

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Mortality Rates in Transplant Recipients and Transplantation Candidates in a High-prevalence COVID-19 Environment.

Nizam Mamode, Zubir Ahmed, Gareth Jones, Neal Banga, Reza Motallebzadeh, Hannah Tolley, Steve Marks, Jelena Stojanovic, Muhammad A Khurram, Raj Thuraisingham, Joyce Popoola, Abbas Ghazanfar, David Game, Kiran Sran, Frank J M F Dor, Gaetano Lucisano, Manish Sinha, Jonathon Olsburgh, Michelle Willicombe,

<h4>Background</h4>The risk of COVID-19 infection in transplant recipients (TRs) is unknown. Patients on dialysis may be exposed to greater risk of infection due to an inability to isolate. Consideration of these competing risks is important before restarting suspended transplant programs. This study compared outcomes in kidney and kidney/pancreas TRs with ... Read more >>

Transplantation (Transplantation)
[2021, 105(1):212-215]

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The Emerging Role of Artificial Intelligence in the Fight Against COVID-19.

Aruni Ghose, Sabyasachi Roy, Nikhil Vasdev, Jonathon Olsburgh, Prokar Dasgupta,

The coronavirus disease 2019 (COVID-19) pandemic has generated large volumes of clinical data that can be an invaluable resource towards answering a number of important questions for this and future pandemics. Artificial intelligence can have an important role in analysing such data to identify populations at higher risk of COVID-19-related ... Read more >>

Eur Urol (European urology)
[2020, 78(6):775-776]

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Capturing the crisis 'golden moment' - A leadership opportunity for overcoming institutional inertia in safety-critical situations.

Petrut Gogalniceanu, Jonathon Olsburgh, Ioannis Loukopoulos, Nick Sevdalis, Nizam Mamode,

Am J Surg (American journal of surgery)
[2020, :]

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Ex vivo delivery of Mirococept: A dose-finding study in pig kidney after showing a low dose is insufficient to reduce delayed graft function in human kidney.

Theodoros Kassimatis, Roseanna Greenlaw, James P Hunter, Abdel Douiri, Clare Flach, Irene Rebollo-Mesa, Laura L Nichols, Anass Qasem, Guilherme Danzi, Jonathon Olsburgh, Martin Drage, Peter J Friend, Flavia Neri, Julieta Karegli, Catherine Horsfield, Richard A Smith, Steven H Sacks,

The complement system plays a pivotal role in the pathogenesis of ischemia-reperfusion injury in solid organ transplantation. Mirococept is a potent membrane-localizing complement inhibitor that can be administered ex vivo to the donor kidney prior to transplantation. To evaluate the efficacy of Mirococept in reducing delayed graft function (DGF) in ... Read more >>

Am J Transplant (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2020, :]

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Safety of ‘hot’ and ‘cold’ site admissions within a high volume urology department in the United Kingdom at the peak of the COVID-19 pandemic

Luke Stroman, Beth Russell, Pinky Kotecha, Anastasia Kantartzi, Luis Ribeiro, Bethany Jackson, Vugar Ismaylov, Adeoye Oluwakanyinsola Debo-Aina, Findlay MacAskill, Francesca Kum, Meghana Kulkarni, Raveen Sandher, Anna Walsh, Ella Doerge, Katherine Guest, Yamini Kailash, Nick Simson, Cassandra McDonald, Elsie Mensah, Li June Tay, Ramandeep Chalokia, Sharon Clovis, Elizabeth Eversden, Jane Cossins, Jonah Rusere, Grace Zisengwe, Louisa Fleure, Leslie Cooper, Kathryn Chatterton, Amelia Barber, Catherine Roberts, Thomasia Azavedo, Jeffrey Ritualo, Harold Omana, Liza Mills, Lily Studd, Oussama El Hage, Rajesh Nair, Sachin Malde, Arun Sahai, Archana Fernando, Claire Taylor, Benjamin Challacombe, Ramesh Thurairaja, Rick Popert, Jonathon Olsburgh, Paul Cathcart, Christian Brown, Marios Hadjipavlou, Ella Di Benedetto, Matthew Bultitude, Jonathon Glass, Tet Yap, Rhana Zakri, Majed Shabbir, Susan Willis, Kay Thomas, Tim O’Brien, Muhammad Shamim Khan, Prokar Dasgupta,

<h4>Background</h4> Contracting COVID-19 peri-operatively has been associated with a mortality rate as high as 23%, making prevention vital. <h4>Objectives</h4> The primary objective is to determine safety of surgical admissions and procedures during the height of the COVID-19 pandemic using ‘hot’ and ‘cold’ sites. The secondary objective is to determine risk ... Read more >>

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Prophylaxis of Wound Infections-antibiotics in Renal Donation (POWAR): A UK Multicentre Double Blind Placebo Controlled Randomised Trial.

Zubir Ahmed, Raphael Uwechue, Pankaj Chandak, David van Dellen, Jamie Barwell, Sarah Heap, Laszlo Szabo, Carolyn Hemsley, Jonathon Olsburgh, Nicos Kessaris, Nizam Mamode,

<h4>Background</h4>Postoperative infection after hand-assisted laparoscopic donor nephrectomy (HALDN) confers significant morbidity to a healthy patient group. Current UK guidelines cite a lack of evidence for routine antibiotic prophylaxis. This trial assessed if a single preoperative antibiotic dose could reduce post HALDN infections.<h4>Methods</h4>Eligible donors were randomly and blindly allocated to preoperative ... Read more >>

Ann Surg (Annals of surgery)
[2020, 272(1):65-71]

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Management of Renal Cell Carcinoma and Other Renal Masses in the Kidney Graft.

Hannah Warren, Jonathon Olsburgh,

PURPOSE OF REVIEW:Renal masses in the kidney graft pose an important clinical dilemma, balancing graft function against the need for cancer control. RECENT FINDINGS:Donor origin cancers in the renal graft can be classified as 'donor transmitted' or 'donor derived'. The landmark TracerX Renal changed our understanding of renal cell carcinoma ... Read more >>

Curr Urol Rep (Current urology reports)
[2020, 21(1):8]

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Comparison Between Robotic and Laparoscopic or Open Anastomoses: A Systematic Review and Meta-Analysis.

Ioannis D Kostakis, Harkiran Sran, Raphael Uwechue, Pankaj Chandak, Jonathon Olsburgh, Nizam Mamode, Ioannis Loukopoulos, Nicos Kessaris,

Introduction:Robotic surgery has been increasingly used in fashioning various surgical anastomoses. Our aim was to collect and analyze outcomes related to anastomoses performed using a robotic approach and compare them with those done using laparoscopic or open approaches through meta-analysis. Methods:A systematic review was conducted for articles comparing robotic with ... Read more >>

Robot Surg (Robotic surgery (Auckland))
[2019, 6:27-40]

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The MIC-KEY button vesicostomy: a superior alternative for suprapubic drainage?

James J Y Chong, Jai Seth, Elaine Hazell, Winnie Nugent, Sachin Malde, Claire Taylor, Arun Sahai, Jonathon Olsburgh,

<h4>Objectives</h4>To evaluate the MIC-KEY button vesicostomy as an alternative to indwelling suprapubic catheters (SPCs) for bladder drainage in adults.<h4>Patients and methods</h4>Phase II pilot study prospectively evaluating patients with indwelling SPCs that were converted to MIC-KEY buttons, or cystoscopic-guided de novo insertion, between November 2014 and February 2019. In all, 15 ... Read more >>

BJU Int (BJU international)
[2020, 125(2):299-303]

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Dissemination of a novel organ perfusion technique: ex vivo normothermic perfusion of deceased donor kidneys.

Pankaj Chandak, Benedict L Phillips, Raphael Uwechue, Emily Thompson, Lucy Bates, Ibrahim Ibrahim, Avinash Sewpaul, Rodrigo Figueiredo, Jonathon Olsburgh, Sarah Hosgood, Michael L Nicholson, Colin Wilson, Chris J Callaghan,

Ex vivo normothermic perfusion (EVNP) technology is a promising means of organ preservation, assessment, and preconditioning prior to kidney transplantation, which has been pioneered by a single group. We describe the challenges of setting up clinical EVNP programs in 2 new centers, as well as early patient outcomes. Governance, training, ... Read more >>

Artif Organs (Artificial organs)
[2019, 43(11):E308-E319]

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Outcomes in Third and Fourth Kidney Transplants Based on the Type of Donor.

Dilan Dabare, Theodoros Kassimatis, James Hodson, Muhammad Arslan Khurram, Georgios Papadakis, Gianluca Rompianesi, Olivia Shaw, Nikolaos Karydis, Chris Callaghan, Jonathon Olsburgh, Nizam Mamode, Nicos Kessaris, Ioannis Loukopoulos,

BACKGROUND:An increasing number of patients are requiring multiple retransplants. We assessed outcomes of third and fourth kidney transplants, to aid decision making on the most suitable donor type. METHODS:Data were collected retrospectively for 2561 transplants, including 69 third and 8 fourth, performed from 2000 to 2017. Demographics and outcomes for ... Read more >>

Transplantation (Transplantation)
[2019, 103(7):1494-1503]

Cited: 1 time

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UTI in kidney transplant.

Daniel Ness, Jonathon Olsburgh,

Urinary tract infection (UTI) remains the most common type of infection contracted by kidney transplant patients. UTI reduces both patient and graft survival. Understanding and managing UTI in transplant patients requires an appreciation of their unique anatomy and physiology. Both the transplant and native urinary systems can be affected by ... Read more >>

World J Urol (World journal of urology)
[2020, 38(1):81-88]

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Urinary cell-free DNA and UTI; the age of 'omics'.

Rhana Hassan Zakri, Jonathon Olsburgh,

Nat Rev Urol (Nature reviews. Urology)
[2018, 15(12):727-728]

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Diagnosis and management of asymptomatic bacteriuria in kidney transplant recipients: a survey of current practice in Europe.

Julien Coussement, Umberto Maggiore, Oriol Manuel, Anne Scemla, Francisco López-Medrano, Evi V Nagler, José María Aguado, Daniel Abramowicz, , , ,

Background:Asymptomatic bacteriuria is frequent in kidney transplant recipients (KTRs). However, there is no consensus on diagnosis or management. We conducted a European survey to explore current practice related to the diagnosis and management of asymptomatic bacteriuria in adult KTRs. Methods:A panel of experts from the European Renal Association-European Dialysis Transplant ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2018, 33(9):1661-1668]

Cited: 3 times

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Management of Localised Prostate Cancer in Kidney Transplant Patients: A Systematic Review from the EAU Guidelines on Renal Transplantation Panel.

Vital Hevia, Romain Boissier, Óscar Rodríguez-Faba, Claire Fraser-Taylor, Rhana Hassan-Zakri, Enrique Lledo, Heinz Regele, Klemens Buddde, Arnaldo Figueiredo, Jonathon Olsburgh, Alberto Breda,

<h4>Context</h4>Cancer development after kidney transplant (KT) has become a major problem, and currently, it is one of the primary causes of death in this population. Urological cancers after KT such as prostate cancer (PCa) have also increased, partly due to the increasing age of recipients and prolonged survival. PCa is ... Read more >>

Eur Urol Focus (European urology focus)
[2018, 4(2):153-162]

Cited: 1 time

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To Stent or Not To Stent, That Is the Question.

Amy Nagle, Jonathon Olsburgh,

With the increasing complexity of donor organs, recipients, training, and departmental standardisation, routine ureteric stent placement should be advocated. Transplant centres should consider utilising novel technologies for transplant stent removal for a simpler, cheaper procedure that can be performed in any outpatient department. ... Read more >>

Eur Urol Focus (European urology focus)
[2018, 4(2):216-218]

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European Association of Urology Guidelines on Renal Transplantation: Update 2018.

Oscar Rodríguez Faba, Romain Boissier, Klemens Budde, Arnaldo Figueiredo, Claire Fraser Taylor, Vital Hevia, Enrique Lledó García, Heinz Regele, Rhana Hassan Zakri, Jonathon Olsburgh, Alberto Breda,

<h4>Context</h4>The European Association of Urology (EAU) panel on renal transplantation (RT) has released an updated version of the RT guidelines.<h4>Objective</h4>To present the 2018 EAU guidelines on RT.<h4>Evidence acquisition</h4>A broad and comprehensive scoping exercise was performed, encompassing all areas of RT guidelines published between January 1, 2007, and May 31, 2016. ... Read more >>

Eur Urol Focus (European urology focus)
[2018, 4(2):208-215]

Cited: 5 times

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A novel 3D-printed hybrid simulation model for robotic-assisted kidney transplantation (RAKT).

Raphael Uwechue, Petrut Gogalniceanu, Nicos Kessaris, Nick Byrne, Pankaj Chandak, Jonathon Olsburgh, Kamran Ahmed, Nizam Mamode, Ioannis Loukopoulos,

Robotic-assisted kidney transplantation (RAKT) offers key benefits for patients that have been demonstrated in several studies. A barrier to the wider uptake of RAKT is surgical skill acquisition. This is exacerbated by the challenges of modern surgery with reduced surgical training time, patient safety concerns and financial pressures. Simulation is ... Read more >>

J Robot Surg (Journal of robotic surgery)
[2018, 12(3):541-544]

Cited: 5 times

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Effectiveness and Harms of Using Kidneys with Small Renal Tumors from Deceased or Living Donors as a Source of Renal Transplantation: A Systematic Review.

Vital Hevia, Rhana Hassan Zakri, Claire Fraser Taylor, Harman Maxim Bruins, Romain Boissier, Enrique Lledo, Heinz Regele, Klemens Budde, Arnaldo Figueiredo, Alberto Breda, Cathy Yuhong Yuan, Jonathon Olsburgh,

CONTEXT:Kidney transplantation is the best treatment for patients with end-stage renal disease. Incidence of small renal masses (SRMs), which most frequently are renal cell carcinomas (RCCs), is highest in patients aged >60 yr. The increasing age of donors can lead to the diagnosis of a higher number of SRMs when ... Read more >>

Eur Urol Focus (European urology focus)
[2019, 5(3):508-517]

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Management of Abdomino-scrotal hydrocele (ASH)/Scrotal-inguino-retroperitoneal (SIR) hydrocele in a renal transplant patient.

Rohit Srinivasan, Martin Drage, Jonathon Olsburgh,

Abdomino-scrotal hydrocele (ASH) is a very rare clinical entity. It is an unusual condition, in which there is an hourglass communication between a large hydrocele and the retroperitoneal space, through the inguinal canal. First described by Dupuytren in 1834 and defined by Bickle in 1919, the condition is rarely seen. ... Read more >>

J Surg Case Rep (Journal of surgical case reports)
[2017, 2017(10):rjx203]

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Insights in Transplanting Complex Pediatric Renal Recipients With Vascular Anomalies.

Pankaj Chandak, Nicos Kessaris, Chris J Callaghan, Francis Calder, Jelena Stojanovic, Jonathon Olsburgh, Martin Drage, Helen Hume-Smith, Zubir Ahmed, Anna Adamusiak, Derek Roebuck, Colin Forman, Stephen D Marks, Nizam Mamode,

<h4>Background</h4>Children with end-stage kidney disease may have coexisting iatrogenic or congenital vascular anomalies making transplantation difficult. We describe our approach in 5 recipients with vascular anomalies and significant comorbidities, including one case of blood group incompatibility.<h4>Methods</h4>Five children aged 3 to 17 years (median, 7 years), weighing 14 to 34 kg ... Read more >>

Transplantation (Transplantation)
[2017, 101(10):2562-2570]

Cited: 1 time

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The Risk of Tumour Recurrence in Patients Undergoing Renal Transplantation for End-stage Renal Disease after Previous Treatment for a Urological Cancer: A Systematic Review.

Romain Boissier, Vital Hevia, Harman Max Bruins, Klemens Budde, Arnaldo Figueiredo, Enrique Lledó-García, Jonathon Olsburgh, Heinz Regele, Claire Fraser Taylor, Rhana Hassan Zakri, Cathy Yuhong Yuan, Alberto Breda,

<h4>Context</h4>Renal transplantation is the gold standard renal replacement therapy in end-stage renal disease owing to its superior survival and quality of life compared with dialysis. When the potential recipient has a history of cancer, the waiting period before renal transplantation is usually based on the Cincinnati Registry.<h4>Objective</h4>To systematically review all ... Read more >>

Eur Urol (European urology)
[2018, 73(1):94-108]

Cited: 6 times

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A Re-evaluation of Discarded Deceased Donor Kidneys in the UK: Are Usable Organs Still Being Discarded?

Shruti Mittal, Anna Adamusiak, Catherine Horsfield, Ioannis Loukopoulos, Nikolaos Karydis, Nicos Kessaris, Martin Drage, Jonathon Olsburgh, Christopher Je Watson, Chris J Callaghan,

<h4>Background</h4>A significant proportion of procured deceased donor kidneys are subsequently discarded. The UK Kidney Fast-Track Scheme (KFTS) was introduced in 2012, enabling kidneys at risk of discard to be simultaneously offered to participating centers. We undertook an analysis of discarded kidneys to determine if unnecessary organ discard was still occurring ... Read more >>

Transplantation (Transplantation)
[2017, 101(7):1698-1703]

Cited: 4 times

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Contralateral inguinal herniation of a transplant ureter causing obstructive uropathy in a renal transplant recipient.

Niyati Lobo, Fiona McCaig, Jonathon Olsburgh,

Ipsilateral inguinal herniation of the transplanted ureter has been reported as a rare cause of obstructive uropathy in renal transplant recipients. A 73-year-old man presented with acute renal failure 29 years after receiving a deceased donor renal transplant. Radiological investigations demonstrated marked hydronephrosis of the left iliac fossa transplant kidney and ... Read more >>

BMJ Case Rep (BMJ case reports)
[2017, 2017:]

Cited: 1 time

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The Utility of Routine Ultrasound Imaging after Elective Transplant Ureteric Stent Removal.

Bibek Das, Dorian Hobday, Jonathon Olsburgh, Chris Callaghan,

Background. Ureteric stent insertion during kidney transplantation reduces the incidence of major urological complications (MUCs). We evaluated whether routine poststent removal graft ultrasonography (PSRGU) was useful in detecting MUCs before they became clinically or biochemically apparent. Methods. A retrospective analysis was undertaken of clinical outcomes following elective stent removals from ... Read more >>

J Transplant (Journal of transplantation)
[2016, 2016:1231567]

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