Full Text Journal Articles by
Author John M Dennis

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Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes.

Anand Thakarakkattil Narayanan Nair, Agata Wesolowska-Andersen, Caroline Brorsson, Aravind Lathika Rajendrakumar, Simona Hapca, Sushrima Gan, Adem Y Dawed, Louise A Donnelly, Rory McCrimmon, Alex S F Doney, Colin N A Palmer, Viswanathan Mohan, Ranjit M Anjana, Andrew T Hattersley, John M Dennis, Ewan R Pearson,

Type 2 diabetes (T2D) is a complex chronic disease characterized by considerable phenotypic heterogeneity. In this study, we applied a reverse graph embedding method to routinely collected data from 23,137 Scottish patients with newly diagnosed diabetes to visualize this heterogeneity and used partitioned diabetes polygenic risk scores to gain insight ... Read more >>

Nat Med (Nature medicine)
[2022, 28(5):982-988]

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Correction to: DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life.

Nicholas J Thomas, John M Dennis, Seth A Sharp, Akaal Kaur, Shivani Misra, Helen C Walkey, Desmond G Johnston, Nick S Oliver, William A Hagopian, Michael N Weedon, Kashyap A Patel, Richard A Oram,

Diabetologia (Diabetologia)
[2022, 65(1):258]

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