Full Text Journal Articles by
Author Jochen Schmitt

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Correction to: Impact of safety warnings for fluoroquinolones on prescribing behaviour. Results of a cohort study with outpatient routine data.

Ulrike Georgi, Falko Tesch, Jochen Schmitt, Katja de With,

Infection (Infection)
[2021, 49(5):1077-1078]

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Use of Patient-reported Outcome Measures and Patient-reported Experience Measures within Evaluation Studies of Telemedicine Applications: Systematic Review.

Andreas Knapp, Lorenz Harst, Stefan Hager, Jochen Schmitt, Madlen Scheibe,

<h4>Background</h4>With the rise of digital health technologies and telemedicine services, the need for evidence-based evaluation is growing. Patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) are recommended as an essential part of comprehensive and multidisciplinary evaluation studies on telemedicine applications. For the first time, a systematic review has been ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2021, :]

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An individualized decision aid for physicians and patients for total knee replacement in osteoarthritis (Value-based TKR study): study protocol for a multi-center, stepped wedge, cluster randomized controlled trial.

Toni Lange, Stefanie Deckert, Franziska Beyer, Waldemar Hahn, Natascha Einhart, Martin Roessler, Martin Sedlmayr, Jochen Schmitt, Jörg Lützner,

<h4>Background</h4>Total knee replacement (TKR) is one of the most commonly performed routine procedures in the world. Prognostic studies indicate that the number of TKR will further increase constituting growing burden on healthcare systems. There is also substantial regional heterogeneity in TKR rates within and between countries. Despite the known therapeutic ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2021, 22(1):783]

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Do certified cancer centers provide more cost-effective care? A health economic analysis of colon cancer care in Germany using administrative data.

Chih-Yuan Cheng, Thomas Datzmann, Diego Hernandez, Jochen Schmitt, Michael Schlander,

Hospital certification has become an important measure to improve cancer care quality, with the potential effect of prolonging patient survival and reducing medical spending. However, yet to be explored is the cost-effectiveness of cancer care provided in certified hospitals, considering significant additional costs incurred from certification requirements. We performed a ... Read more >>

Int J Cancer (International journal of cancer)
[2021, 149(10):1744-1754]

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Can we trust the standardized mortality ratio? A formal analysis and evaluation based on axiomatic requirements.

Martin Roessler, Jochen Schmitt, Olaf Schoffer,

<h4>Background</h4>The standardized mortality ratio (SMR) is often used to assess and compare hospital performance. While it has been recognized that hospitals may differ in their SMRs due to differences in patient composition, there is a lack of rigorous analysis of this and other-largely unrecognized-properties of the SMR.<h4>Methods</h4>This paper proposes five ... Read more >>

PLoS One (PloS one)
[2021, 16(9):e0257003]

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Health system efficiency and democracy: A public choice perspective.

Martin Roessler, Jochen Schmitt,

Due to increasing demand and scarce financial resources for healthcare, health system efficiency has become a major topic in political and scientific debates. While previous studies investigating determinants of health system efficiency focused primarily on economic and social influence factors, the role of the political regime has been neglected. In ... Read more >>

PLoS One (PloS one)
[2021, 16(9):e0256737]

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[Interdisciplinary care path and potential IT support for people with rare diseases in Germany].

Michele Zoch, Brita Sedlmayr, Andreas Knapp, Franziska Bathelt, Sven Helfer, Jochen Schmitt, Martin Sedlmayr,

<h4>Introduction</h4>Due to the high variability and, at the same time, rare occurrence of rare diseases, the diagnosis of these patients (approx. 4 million people in Germany) can turn into an odyssey. The large time interval between the appearance of symptoms and the final diagnosis of the rare disease leads to ... Read more >>

Z Evid Fortbild Qual Gesundhwes (Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen)
[2021, 165:68-76]

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Status report on the atopic dermatitis registry TREATgermany.

Doreen Siegels, Eva Haufe, Luise Heinrich, Thomas Werfel, Stephan Weidinger, Jochen Schmitt, ,

<h4>Background</h4>The TREATgermany registry collects data from children, adolescents, and adults with moderate-to-severe atopic dermatitis (AD) in Germany. For this purpose, clinical and patient-reported outcomes, the course of the disease, and applied therapies are observed.<h4>Methods</h4>TREATgermany recruits patients with moderate-to-severe AD according to the diagnostic criteria of the UK Working Party, an ... Read more >>

Allergol Select (Allergologie select)
[2021, 5:274-286]

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Quality of life of GIST patients with and without current tyrosine kinase inhibitor treatment: Cross-sectional results of a German multicentre observational study (PROSa).

Martin Eichler, Daniel Pink, Franka Menge, Jens Jakob, Leopold Hentschel, Stephan Richter, Peter Hohenberger, Bernd Kasper, Dimosthenis Andreou, Susanne Singer, Robert Grützmann, Diana I Dmytrow, Karin Arndt, Armin Tuchscherer, Peter Reichardt, Marit Ahrens, Annegret Kunitz, Johannes Mohm, Martin Bornhäuser, Jochen Schmitt, Markus K Schuler,

<h4>Objective</h4>We investigated the health-related quality of life (HRQoL) of patients with gastrointestinal stromal tumours (GIST).<h4>Methods</h4>In the multicentre PROSa study, the HRQoL of adult GIST patients was assessed between 2017 and 2019 using the European Organisation for Research and Treatment of Cancer HRQoL questionnaire (EORTC QLQ-C30). We performed group comparisons and ... Read more >>

Eur J Cancer Care (Engl) (European journal of cancer care)
[2021, :]

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Are birth outcomes in low risk birth cohorts related to hospital birth volumes? A systematic review.

Felix Walther, Denise Kuester, Anja Bieber, Jürgen Malzahn, Mario Rüdiger, Jochen Schmitt,

<h4>Background</h4>There is convincing evidence that birth in hospitals with high birth volumes increases the chance of healthy survival in high-risk infants. However, it is unclear whether this is true also for low risk infants. The aim of this systematic review was to analyze effects of hospital's birth volume on mortality, ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2021, 21(1):531]

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Independent Use of a Home-Based Telemonitoring App by Older Patients With Multimorbidity and Mild Cognitive Impairment: Qualitative Study.

Madlen Scheibe, Caroline Lang, Diana Druschke, Katrin Arnold, Edwin Luntz, Jochen Schmitt, Vjera Holthoff-Detto,

<h4>Background</h4>The management of multimorbidity is complex and patients have a high burden of disease. When symptoms of dementia also appear, it becomes even more difficult for patients to cope with their everyday lives and manage their diseases. Home-based telemonitoring may support older patients with multimorbidity and mild cognitive impairment (MCI) ... Read more >>

JMIR Hum Factors (JMIR human factors)
[2021, 8(3):e27156]

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Financial toxicity in sarcoma patients and survivors in Germany: results from the multicenter PROSa study.

Matthias Büttner, Susanne Singer, Leopold Hentschel, Stephan Richter, Peter Hohenberger, Bernd Kasper, Dimosthenis Andreou, Daniel Pink, Kathy Taylor, Karin Arndt, Martin Bornhäuser, Jochen Schmitt, Markus K Schuler, Martin Eichler,

<h4>Purpose</h4>Cancer patients have been shown to frequently suffer from financial burden before, during, and after treatment. However, the financial toxicity of patients with sarcoma has seldom been assessed. Therefore, the aim of this study was to evaluate whether financial toxicity is a problem for sarcoma patients in Germany and identify ... Read more >>

Support Care Cancer (Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer)
[2021, :]

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[Characteristics of Innovation Fund-supported Intervention Studies: Review and Document Analysis of Study Protocols, Publications and Final Reports].

Heike Heytens, Felix Walther, Laura Keßler, Daniel Bremer, Elisa Frenz, Martin Härter, Max Geraedts, Thomas Bierbaum, Christian Apfelbacher, Jochen Schmitt,

This prospectively registered review characterizes 50 intervention studies from the 1<sup>st</sup> wave of the Innovation Fund based on study protocols or original articles, among other sources. The mainly (randomized) controlled intervention studies included predominantly adults/seniors in ambulatory care without a regional focus and analyzed treatment processes, clinical and patient outcomes ... Read more >>

Gesundheitswesen (Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)))
[2021, 83(5):e20-e37]

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Different spreading dynamics throughout Germany during the second wave of the COVID-19 pandemic: a time series study based on national surveillance data.

Andreas Schuppert, Katja Polotzek, Jochen Schmitt, Reinhard Busse, Jens Karschau, Christian Karagiannidis,

<h4>Background</h4>The second wave of the COVID-19 pandemic led to substantial differences in incidence rates across Germany.<h4>Methods</h4>Assumption-free k-nearest neighbour clustering from the principal component analysis of weekly incidence rates of German counties groups similar spreading behaviour. Different spreading dynamics was analysed by the derivative plots of the temporal evolution of tuples ... Read more >>

Lancet Reg Health Eur (The Lancet regional health. Europe)
[2021, 6:100151]

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[Routine Practice Data for Evaluating Intervention Effects: Part 2 of the Manual].

Falk Hoffmann, Thomas Kaiser, Christian Apfelbacher, Stefan Benz, Thomas Bierbaum, Karsten Dreinhöfer, Michael Hauptmann, Claus-Dieter Heidecke, Michael Koller, Tanja Kostuj, Olaf Ortmann, Jochen Schmitt, Holger Schünemann, Christof Veit, Wolfgang Hoffmann, Monika Klinkhammer-Schalke,

Gesundheitswesen (Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)))
[2021, 83(6):e40]

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Individualized versus Fixed Positive End-expiratory Pressure for Intraoperative Mechanical Ventilation in Obese Patients: A Secondary Analysis.

Philipp Simon, Felix Girrbach, David Petroff, Nadja Schliewe, Gunther Hempel, Mirko Lange, Thomas Bluth, Marcelo Gama de Abreu, Alessandro Beda, Marcus J Schultz, Paolo Pelosi, Andreas W Reske, Hermann Wrigge, ,

<h4>Background</h4>General anesthesia may cause atelectasis and deterioration in oxygenation in obese patients. The authors hypothesized that individualized positive end-expiratory pressure (PEEP) improves intraoperative oxygenation and ventilation distribution compared to fixed PEEP.<h4>Methods</h4>This secondary analysis included all obese patients recruited at University Hospital of Leipzig from the multicenter Protective Intraoperative Ventilation with ... Read more >>

Anesthesiology (Anesthesiology)
[2021, 134(6):887-900]

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[Routine Practice Data for Evaluating Intervention Effects: Part 2 of the Manual].

Falk Hoffmann, Thomas Kaiser, Christian Apfelbacher, Stefan Benz, Thomas Bierbaum, Karsten Dreinhöfer, Michael Hauptmann, Claus-Dieter Heidecke, Michael Koller, Tanja Kostuj, Olaf Ortmann, Jochen Schmitt, Holger Schünemann, Christof Veit, Wolfgang Hoffmann, Monika Klinkhammer-Schalke,

The evaluation of intervention effects is an important domain of health services research. The ad hoc commission for the use of routine practice data of the German Network for Health Services Research (DNVF) therefore provides this second part of its manual focusing on the use of routine practice data for ... Read more >>

Gesundheitswesen (Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)))
[2021, 83(6):470-480]

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Multiperspective and Multimethod Evaluation of Flexible and Integrative Psychiatric Care Models in Germany: Study Protocol of a Prospective, Controlled Multicenter Observational Study (PsychCare).

Bettina Soltmann, Anne Neumann, Stefanie March, Ines Weinhold, Dennis Häckl, Roman Kliemt, Fabian Baum, Marcel Romanos, Julian Schwarz, Sebastian von Peter, Yuriy Ignatyev, Katrin Arnold, Enno Swart, Martin Heinze, Jochen Schmitt, Andrea Pfennig,

<b>Background:</b> New cross-sectoral mental health care models have been initiated in Germany to overcome the fragmentation of the German health care system. Starting in 2013, flexible and integrative psychiatric care model projects according to §64b SGB V German Social Law (FIT64b) have been implemented. The study "PsychCare" combines quantitative and ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2021, 12:659773]

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[Opportunities and limitations of risk adjustment of quality indicators based on inpatient administrative health data - a workshop report].

Daniel Schwarzkopf, Ulrike Nimptsch, Raphael Graf, Jochen Schmitt, Josef Zacher, Ralf Kuhlen,

<h4>Introduction</h4>The quality indicators of the Initiative Qualitätsmedizin e. V. (IQM) have been developed as triggers to examine treatment processes for opportunities for improvement. Published quality results have partly been used for external quality comparisons in the media. Therefore, member hospitals of IQM demanded to investigate if methods of risk adjustment should ... Read more >>

Z Evid Fortbild Qual Gesundhwes (Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen)
[2021, 163:1-12]

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Postinflammatory hyperpigmentation: protocol for development of a core outcome set for clinical trials.

Bianca Y Kang, Sarah A Ibrahim, Divya Shokeen, Daniel I Schlessinger, Jamie J Kirkham, Jochen Schmitt, Emily Poon, Ian A Maher, Joseph F Sobanko, Todd V Cartee, Murad Alam,

Postinflammatory hyperpigmentation (PIH) is a disorder of pigmentation that is a common presenting complaint, especially in individuals with skin of color. It is associated with a significant psychological burden and decrement of quality of life. Management options include photoprotection, topical lightening agents, and lasers and energy devices. Clinical trials of ... Read more >>

Arch Dermatol Res (Archives of dermatological research)
[2021, :]

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Health-related quality of life in elderly, multimorbid individuals with and without depression and/or mild cognitive impairment using a telemonitoring application.

Caroline Lang, Martin Roessler, Jochen Schmitt, Antje Bergmann, Vjera Holthoff-Detto,

<h4>Purpose</h4>Multimorbidity leads to decreasing health-related quality of life (HRQoL). Telemedicine may help to improve HRQoL. The present study was conducted to show (I) differences in HRQoL and changes in HRQoL over time in elderly, multimorbid individuals with and without depression and/or mild cognitive impairment (MCI) using a telemonitoring application (TMA) ... Read more >>

Qual Life Res (Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation)
[2021, 30(10):2829-2841]

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Prenatal Methamphetamine Exposure: Effects on Child Development.

Lorenz Harst, Stefanie Deckert, Frederik Haarig, Jörg Reichert, Jürgen Dinger, Peter Hellmund, Jochen Schmitt, Mario Rüdiger,

<h4>Background</h4>In Germany, the 12-month prevalence of methamphetamine use among persons aged 15 to 34 is 1.9%. An increasing number of newborns are being born after a prenatal methamphetamine exposure (PME). In 2014, in the German state of Saxony, approximately four out of 1000 newborns were affected.<h4>Methods</h4>This systematic review (Prospero registration ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(18):313-319]

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Skin Barrier and Inflammation Genes Associated with Atopic Dermatitis are Regulated by Interleukin-13 and Modulated by Tralokinumab In vitro.

Maxim A X Tollenaere, Thomas Litman, Lena Moebus, Elke Rodriguez, Dora Stölzl, Katharina Drerup, Thomas Werfel, Jochen Schmitt, Hanne Norsgaard, Stephan Weidinger,

Acta Derm Venereol (Acta dermato-venereologica)
[2021, 101(4):adv00447]

Cited: 1 time

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[Decision for total hip arthroplasty-the surgeons' view].

Anne Postler, Cornelia Lützner, Toni Lange, Jochen Schmitt, Jörg Lützner, Klaus-Peter Günther,

<h4>Background</h4>The decision for total hip arthroplasty (THA) is based on pain, loss of function, radiological changes and failed conservative therapy. These criteria are rarely based on systematic research and have not been integrated in generally accepted treatment guidelines. Aim of our study was, therefore, to analyse which decision criteria German ... Read more >>

Orthopade (Der Orthopade)
[2021, 50(4):278-286]

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Utilization of Interdisciplinary Tumor Boards for Sarcoma Care in Germany: Results from the PROSa Study.

Martin Eichler, Dimosthenis Andreou, Henriette Golcher, Leopold Hentschel, Stephan Richter, Peter Hohenberger, Bernd Kasper, Daniel Pink, Jens Jakob, Hany Ashmawy, Simone Hettmer, Armin Tuchscherer, Matthias Grube, Vitali Heidt, Christina Jentsch, Jessica Pablik, Eva Wardelmann, Karl-Friedrich Kreitner, Ulrich Kneser, Carolin Tonus, Pauline Wimberger, Olaf Schoffer, Peter Reichardt, Markus Wartenberg, Maria Eberlein-Gonska, Martin Bornhäuser, Jochen Schmitt, Markus K Schuler,

<h4>Background</h4>Data on institutional structures of sarcoma care in Germany are scarce. The utilization of an interdisciplinary tumor board (IDTB) is an essential part of modern cancer care. We investigated to which extent and when IDTB are used in sarcoma care. We hypothesized that IDTB before treatment initiation were used more ... Read more >>

Oncol Res Treat (Oncology research and treatment)
[2021, 44(6):301-312]

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