Full Text Journal Articles by
Author Jingjing Duan

Advertisement

Find full text journal articles






Battery-Driven N2 Electrolysis Enabled by High-Entropy Catalysts: From Theoretical Prediction to Prototype Model.

Yuntong Sun, Lei Yu, Shuaishuai Xu, Sicong Xie, Lili Jiang, Jingjing Duan, Junwu Zhu, Sheng Chen,

A small-scale standalone device of nitrogen (N<sub>2</sub> ) splitting holds great promise for producing ammonia (NH<sub>3</sub> ) in a decentralized manner as the compensation or replacement of centralized Haber-Bosch process. However, the design of such a device has been impeded by sluggish kinetics of its half reactions, i.e., cathodic N<sub>2</sub> ... Read more >>

Small (Small (Weinheim an der Bergstrasse, Germany))
[2022, :e2106358]

Cited: 0 times

View full text PDF listing >>



An Inflammatory Response Related Gene Signature Associated with Survival Outcome and Gemcitabine Response in Patients with Pancreatic Ductal Adenocarcinoma.

Zhijun Xiao, Jinyin Li, Qian Yu, Ting Zhou, Jingjing Duan, Zhen Yang, Cuicui Liu, Feng Xu,

<b>Background:</b> Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors with an extremely low 5-year survival rate. Accumulating evidence has unveiled that inflammatory response promotes tumor progression, enhances angiogenesis, and causes local immunosuppression. Herein, we aim to develop an inflammatory related prognostic signature, and found it could be ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:778294]

Cited: 0 times

View full text PDF listing >>



Advertisement

Cryo-EM structure of mouse TRPML2 in lipid nanodiscs.

Xiaojing Song, Jian Li, Miao Tian, Huaiyi Zhu, Xiaohui Hu, Yuting Zhang, Yanru Cao, Heyang Ye, Peter J McCormick, Bo Zeng, Yang Fu, Jingjing Duan, Jin Zhang,

In mammalians, transient receptor potential mucolipin ion channels (TRPMLs) exhibit variable permeability to cations such as Ca2+, Fe2+, Zn2+, and Na+, and can be activated by the phosphoinositide PI(3,5)P2 in the endolysosomal system. Loss or dysfunction of TRPMLs has been implicated in lysosomal storage disorders, infectious diseases, and metabolic diseases. ... Read more >>

J Biol Chem (The Journal of biological chemistry)
[2021, :101487]

Cited: 0 times

View full text PDF listing >>



Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice.

Jingjing Duan, Zhuo Wang, Ran Duan, Chenxinhui Yang, Ruolin Zhao, Qi Feng, Yuanyuan Qin, Jingwei Jiang, Shouyong Gu, Kaiyan Lv, Libo Zhang, Bixia He, Lutz Birnbaumer, Song Yang, Zhen Chen, Yong Yang,

<h4>Background and aims</h4>Globally, NAFLD is one of the most common liver disorders, with an estimated prevalence rate of more than 30% in men and 15% in women and an even higher prevalence in people with type 2 diabetes mellitus. Optimal pharmacologic therapeutic approaches for NAFLD are an urgent necessity.<h4>Approach and ... Read more >>

Hepatology (Hepatology (Baltimore, Md.))
[2022, 75(1):140-153]

Cited: 0 times

View full text PDF listing >>



PTK2 Promotes Uveal Melanoma Metastasis by Activating Epithelial-to-Mesenchymal Transition

Zhongyi Fan, Jingjing Duan, Lei Zhang, Qiong Chen, Wen Xiao, Pu Luo, Ling Shao, Jingye Meng, Jianghong An, Gengwei Zhang, Xiaohua Tan,

<h4>Background: </h4> Uveal melanoma (UM) is an aggressive primary intraocular tumor in adults, with high metastatic capacity and high morbidity. However, the mechanisms of UM metastasis have not been clearly elucidated. <h4>Methods: </h4>: The PTK2 expression and activation were performed in the Cancer Genome Atlas (TCGA) database and 25 patients ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Functional Insights of MraZ on the Pathogenicity of Staphylococcus aureus.

Bingjie Wang, Jingjing Duan, Ye Jin, Qing Zhan, Yanlei Xu, Huilin Zhao, Xinyi Wang, Lulin Rao, Yinjuan Guo, Fangyou Yu,

<h4>Introduction</h4>In recent years, multidrug-resistant methicillin-resistant <i>Staphylococcus aureus</i> has become increasingly prevalent, which raised a huge challenge to antibiotic treatment of infectious diseases. The anti-virulence strategy targeting virulent factors is a promising novel therapy for <i>S. aureus</i> infection. The virulence mechanism of <i>S. aureus</i> was needed to explore deeply to develop ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2021, 14:4539-4551]

Cited: 0 times

View full text PDF listing >>



Chronic Stress-Induced Gene Changes In Vitro and In Vivo: Potential Biomarkers Associated With Depression and Cancer Based on circRNA- and lncRNA-Associated ceRNA Networks.

Ting Zhou, Mingming Li, Zhijun Xiao, Jian Cai, Weiwei Zhao, Jingjing Duan, Zhen Yang, Zhijun Guo, Yitian Chen, Weijia Cai, Piaopiao Huang, Chaoyong He, Feng Xu,

Circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs) have been considered as biomarkers or regulators in many diseases. However, the exact role of circRNA- or lncRNA-mediated competing endogenous RNA (ceRNA) networks in the modulation of depression pathogenesis-relevant processes is not clear. In this study, we profiled whole transcriptome in depression ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:744251]

Cited: 0 times

View full text PDF listing >>



Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.

Yuting Zhang, Hongxia Gao, Xiaohui Hu, Qisheng Wang, Fanglin Zhong, Xuelan Zhou, Cheng Lin, Yang Yang, Junkang Wei, Weian Du, Huaiqiu Huang, Huan Zhou, Wei He, Hua Zhang, Yuting Zhang, Peter J McCormick, Jinheng Fu, Dan Wang, Yang Fu, Xiaolu Lu, Tengfei Zhang, Jingjing Duan, Bingjie Qin, Haihai Jiang, Jun Luo, Yan Zhang, Qi Chen, Qunfeng Luo, Lin Cheng, Zheng Zhang, Jin Zhang, Jian Li,

Over the past 20 years, the severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome CoV (MERS-CoV), and SARS-CoV-2 emerged, causing severe human respiratory diseases throughout the globe. Developing broad-spectrum drugs would be invaluable in responding to new, emerging coronaviruses and to address unmet urgent clinical needs. Main protease (M<sup>pro</sup>; ... Read more >>

J Virol (Journal of virology)
[2022, 96(1):e0125321]

Cited: 0 times

View full text PDF listing >>



A Novel Effect of PDLIM5 In α7 Nicotinic Acetylcholine Receptors Up-Regulation And Surface Expression

Zilin Li, Chenyu Gou, Wenhui Wang, Yuan Li, Yu Cui, Jingjing Duan, Yuan Chen,

α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are expressed widely in the brain, where they contribute to a variety of behaviors including arousal and cognition, participate in a number of neurodegenerative disorders including Alzheimer’s and Parkinson’s disease, and is responsible for nicotine addiction. Although recent studies indicate that the PDZ-containing proteins ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



[Exploration and practice on the opening and sharing management mode of undergraduate experimental teaching instruments and laboratory information management system (LIMS) under the background of "Double first-class"].

Yongqin He, Jingjing Duan, Qian Chen, Xiaoling Guo,

In order to explore the role of the opening and sharing management mode (OSMM) of undergraduate experiment teaching instruments in fostering talents under the "Double first-class" initiative, the importance of laboratory information management system (LIMS) in the OSMM was discussed, in light of the experience and shortcomings of developing an ... Read more >>

Sheng Wu Gong Cheng Xue Bao (Sheng wu gong cheng xue bao = Chinese journal of biotechnology)
[2021, 37(9):3361-3367]

Cited: 0 times

View full text PDF listing >>



Antitumor Effect of Fluoxetine on Chronic Stress-Promoted Lung Cancer Growth via Suppressing Kynurenine Pathway and Enhancing Cellular Immunity.

Zhen Yang, Zhuman Li, Zhijun Guo, Yu Ren, Ting Zhou, Zhijun Xiao, Jingjing Duan, Chuangchuang Han, Yuanchi Cheng, Feng Xu,

<b>Background:</b> Chronic stress promotes cancer growth. Antidepressant fluoxetine (FLX) is usually prescribed for cancer patients with comorbid depression. FLX displays inhibition on cancer cell proliferation, however, the <i>in vivo</i> activity has not been investigated. <b>Methods:</b> We explored the antitumor effect of FLX in subcutaneous transplanted lung cancer cells in a ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:685898]

Cited: 0 times

View full text PDF listing >>



iRGD-modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation.

Dan Lin, Haiyang Zhang, Rui Liu, Ting Deng, Tao Ning, Ming Bai, Yuchong Yang, Kegan Zhu, Junyi Wang, Jingjing Duan, Shaohua Ge, Bei Sun, Guoguang Ying, Yi Ba,

Fatty acid oxidation (FAO) plays a vital role in drug resistance in cancer cells. Carnitine palmitoyltransferase 1A (CPT1A), a key enzyme of FAO, is widely recognized as an emerging therapeutic target. Here, we confirmed that CPT1A was heterogeneously expressed in colon cancer cells, with a high expression in oxaliplatin-resistant cells ... Read more >>

Mol Oncol (Molecular oncology)
[2021, 15(12):3430-3446]

Cited: 1 time

View full text PDF listing >>



The paradoxical pharmacological mechanisms of lenalidomide and bortezomib in the treatment of multiple myeloma.

Busong Wang, Jingjing Duan, Liang Zhou,

The combination of bortezomib (Velcade, PS-341) and lenalidomide (Revlimid) for the treatment of multiple myeloma was proved by USA Food and Drug Administration in 2006. Lenalidomide prevents the proliferation of multiple myeloma cells through binding to cereblon and promoting the ubiquitinational degradation of IKZF1 (Ikaros)/IKZF3 (Aiolos). However, the proteasome inhibitor ... Read more >>

Anticancer Drugs (Anti-cancer drugs)
[2021, 32(3):227-232]

Cited: 1 time

View full text PDF listing >>



In vivo noninvasive and rapid evaluation of pearls in freshwater mussels based on micro-CT

Rongbin Ding, Lei Liu, Zhenying Hu, Andong Wu, Huaiyi Zhu, Qingxin Ruan, Huiming Qiu, Yijiang Hong, Beijuan Hu, Jingjing Duan,

It takes years to build up a thick layer of nacre in a cultured pearl. The initial fixation and formation of the pearl nucleus, and the growth rate of nacre are important indicators to pearl cultivators. These indicators are traditionally assessed by opening the shellfish for pearl acquisition mechanically causing ... Read more >>

Aquaculture (Aquaculture (Amsterdam, Netherlands))
[2021, 534:Not Available]

Cited: 0 times

View full text PDF listing >>



The NMDAR GluN1-1a C-terminus binds to CaM and regulates synaptic function.

Liang Zhou, Jingjing Duan,

The binding of calmodulin (CaM) to NMDAR (N-methyl-D-aspartate receptor) GluN1 C-terminus is required for cacium (Ca<sup>2+</sup>)/calmodulin (CaM)-dependent inactivation of NMDAR. Previously, we found that GluN1 C-terminus translocated to nucleus, and regulated synaptic transmission. However, whether GluN1 C-terminus containing the nuclear localization signaling regulates the cellular distribution of CaM, and the ... Read more >>

Biochem Biophys Res Commun (Biochemical and biophysical research communications)
[2021, 534:323-329]

Cited: 0 times

View full text PDF listing >>



High yield and mitigation of N-loss from paddy fields obtained by irrigation using optimized application of sewage tail water

Aijing Yin, Jingjing Duan, Lihong Xue, Yanfang Feng, Evangelos Petropoulos, Linzhang Yang,

Reuse of treated wastewater effluent for crop irrigation can be a promising strategy to substitute/reduce chemical fertilizers and mitigate contamination of water environment. The effect of the effluent irrigation strategies on crop yield and nitrogen (N) loss to the environment have not been yet well explored. In the present study, ... Read more >>

(Agriculture, ecosystems & environment.)
[2020, 304:Not Available]

Cited: 0 times

View full text PDF listing >>



Combination of canstatin and arsenic trioxide suppresses the development of hepatocellular carcinoma.

Fan Zhang, Jingjing Duan, Hailin Song, Li Yang, Ming Zhou, Xuewen Wang,

Complication of arsenic trioxide (ATO) and other drugs in cancer treatment has attracted much focus, but is limitedly investigated in hepatocellular carcinoma (HCC). This study aimed to explore the role of ATO combined with canstatin in HCC. HepG2 cells were treated with different concentrations of ATO with or without canstatin, ... Read more >>

Drug Dev Res (Drug development research)
[2021, 82(3):430-439]

Cited: 1 time

View full text PDF listing >>



Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode.

Jian Li, Xuelan Zhou, Yan Zhang, Fanglin Zhong, Cheng Lin, Peter J McCormick, Feng Jiang, Jun Luo, Huan Zhou, Qisheng Wang, Yang Fu, Jingjing Duan, Jin Zhang,

Sci Bull (Beijing) (Science bulletin)
[2021, 66(7):661-663]

Cited: 9 times

View full text PDF listing >>



Structure of SARS-CoV-2 main protease in the apo state.

Xuelan Zhou, Fanglin Zhong, Cheng Lin, Xiaohui Hu, Yan Zhang, Bing Xiong, Xiushan Yin, Jinheng Fu, Wei He, Jingjing Duan, Yang Fu, Huan Zhou, Peter J McCormick, Qisheng Wang, Jian Li, Jin Zhang,

Sci China Life Sci (Science China. Life sciences)
[2021, 64(4):656-659]

Cited: 2 times

View full text PDF listing >>



Crystal structure of SARS-CoV-2 main protease in complex with a Chinese herb inhibitor shikonin

Jian Li, Xuelan Zhou, Yan Zhang, Fanglin Zhong, Cheng Lin, Peter McCormick, Feng Jiang, Huan Zhou, Qisheng Wang, Jingjing Duan, Jin Zhang,

Main protease (M pro , also known as 3CLpro) has a major role in the replication of coronavirus life cycle and is one of the most important drug targets for anticoronavirus agents. Here we report the crystal structure of main protease of SARS-CoV-2 bound to a previously identified Chinese herb ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Patients with advanced non-small cell lung cancer with EGFR mutations in addition to complex mutations treated with osimertinib have a poor clinical outcome: A real-world data analysis.

Nijia Chang, Jingjing Duan, Lingxiong Wang, Zhouhuan Dong, Zhefeng Liu,

The present study aimed to investigate the clinical characteristics and outcomes of patients with advanced non-small cell lung cancer (NSCLC) treated with osimertinib, and focused on the resistance mechanism to osimertinib in a real-world setting. Data from 128 patients with advanced NSCLC who were treated with osimertinib between March 2015 ... Read more >>

Oncol Lett (Oncology letters)
[2020, 20(3):2266-2272]

Cited: 3 times

View full text PDF listing >>



[Management pattern of undergraduate teaching laboratory with a focus on creating the educational environment].

Xiaoling Guo, Yongqin He, Jun Liu, Jingjing Duan,

The teaching laboratory is the central place to teach lab courses to undergraduate students. It is thus critical to evaluate how lab skills of students will be affected by the management of this lab. This study attempts to introduce the 6S concept, referring to "Seiri", "Seiton", "Seiso", "Seiketsu", "Shisuke", and ... Read more >>

Sheng Wu Gong Cheng Xue Bao (Sheng wu gong cheng xue bao = Chinese journal of biotechnology)
[2020, 36(7):1459-1464]

Cited: 0 times

View full text PDF listing >>



Loss of a Negative Feedback Loop between IRF8 and AR Promotes Prostate Cancer Growth and Enzalutamide Resistance.

Hongxi Wu, Linjun You, Yan Li, Zhili Zhao, Guangjiang Shi, Zhen Chen, Zhuo Wang, Xianjing Li, Shijia Du, Wanli Ye, Xiaofang Gao, Jingjing Duan, Yan Cheng, Weiyan Tao, Jinsong Bian, Jin-Rong Zhou, Qingyi Zhu, Yong Yang,

In incurable castration-resistant prostate cancer (CRPC), resistance to the novel androgen receptor (AR) antagonist enzalutamide is driven mainly by AR overexpression. Here we report that the expression of interferon regulatory factor 8 (IRF8) is increased in primary prostate cancer but decreased in CRPC compared with normal prostate tissue. Decreased expression ... Read more >>

Cancer Res (Cancer research)
[2020, 80(13):2927-2939]

Cited: 1 time

View full text PDF listing >>



Phosphorus Vacancies that Boost Electrocatalytic Hydrogen Evolution by Two Orders of Magnitude.

Jingjing Duan, Sheng Chen, César A Ortíz-Ledón, Mietek Jaroniec, Shi-Zhang Qiao,

Vacancy engineering is an effective strategy to manipulate the electronic structure of electrocatalysts to improve their performance, but few reports focus on phosphorus vacancies (Pv). Herein, the creation of Pv in metal phosphides and investigation of their role in alkaline electrocatalytic hydrogen evolution reaction (HER) is presented. The Pv-modified catalyst ... Read more >>

Angew Chem Int Ed Engl (Angewandte Chemie (International ed. in English))
[2020, 59(21):8181-8186]

Cited: 3 times

View full text PDF listing >>



Effects of domestic sewage from different sources on greenhouse gas emission and related microorganisms in straw-returning paddy fields.

Mengyao Li, Lihong Xue, Beibei Zhou, Jingjing Duan, Zhu He, Xugang Wang, Xiaofeng Xu, Linzhang Yang,

Reusing domestic sewage for crop irrigation is a promising practice, particularly in developing countries, since it is a substitute for chemical fertilizer and reduces water contamination. More attention was paid to the effect of sewage irrigation on crop yield and soil nutrients, but little attention was paid to greenhouse gas ... Read more >>

Sci Total Environ (The Science of the total environment)
[2020, 718:137407]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.0133 s