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Author Jing Wang

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"Dual-Key-and-Lock" dual drug carrier for dual mode imaging guided chemo-photothermal therapy.

Feng Tian, Bin Chi, Chen Xu, Caixue Lin, Zushun Xu, Andrew K Whittaker, Cheng Zhang, Ling Li, Jing Wang,

Drug resistance and side effects are the two main problems of chemotherapy. In order to address these big challenges, [email protected], which has the ability to co-deliver both the hydrophobic drug doxorubicin hydrochloride (DOX) and the hydrophilic drug ibuprofen (IBU), is constructed to achieve synergistic treatment. The drug-loaded nanoparticle consists of ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(22):6212-6224]

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Fe-Ni metal-organic frameworks with prominent peroxidase-like activity for the colorimetric detection of Sn2+ ions.

Ye Hu, Chaochao Yue, Jing Wang, Yuhua Zhang, Wenhui Fang, Jiaqi Dang, Ying Wu, Hong Zhao, Zengxi Li,

Fe-Ni-MOFs with different amounts of Fe are synthesized through a two-step template etching method. Kinetic analysis indicates that Fe-Ni-MOF exhibits prominent intrinsic peroxidase-like activity, which could catalytically oxidize 3,3',5,5'-tetramethylbenzidine (TMB) to produce oxidized TMB (oxTMB) with a blue color. As a peroxidase-mimicking MOF, Fe-Ni-MOF with its efficient stable catalysis properties ... Read more >>

Analyst (The Analyst)
[2020, 145(19):6349-6356]

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Early galactooligosaccharide intervention alters the metabolic profile, improves the antioxidant capacity of mitochondria and activates the AMPK/Nrf2 signaling pathway in suckling piglet liver.

Jue Wang, Shiyi Tian, Jing Wang, Weiyun Zhu,

The suckling stage is a critical window time for the development of human and animal neonates. Our previous study found that an early-life galactooligosaccharide (GOS) intervention could improve the growth status of suckling piglets; however, the difference in the metabolic status between different treatment groups still remains unclear. In the ... Read more >>

Food Funct (Food & function)
[2020, 11(8):7280-7292]

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Theoretically designed two-dimensional γ-C4O as an effective gas separation membrane for hydrogen purification.

Cai Ning, Yadong Zhang, Jing Wang, Haiqi Gao, Chuanyun Xiao, Zhaoshun Meng, Huilong Dong,

A high-performance gas separation membrane for hydrogen (H2) purification is still highly desirable for the sustainable development of our society. Based on the structure of γ-graphyne, we theoretically designed the two-dimensional nanomaterials γ-C4X (X = O, S or Se) with intrinsic pores that may be suitable for gas separation. By ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2020, 22(35):19492-19501]

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Functionalized biomaterials to combat biofilms.

Dan-Ni Huang, Jing Wang, Ke-Feng Ren, Jian Ji,

Pathogenic microbial biofilms that readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies towards biofilms, leaving a thought-provoking question: how to tackle the problem of established biofilms? In this review, we briefly summarize the functionalized biomaterials ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(15):4052-4066]

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Nano-crystalline cellulose-coated magnetic nanoparticles for affinity adsorption of glycoproteins.

Jiaying Zhang, Xiangyu Feng, Jing Wang, Guozhen Fang, Jifeng Liu, Shuo Wang,

A new core-shell structured nanomaterial based on Fe3O4 nanoparticles and 2,3-dialdehyde nanocrystalline cellulose (DAC) coating and its high efficiency in the preconcentration of glycoproteins were described in this work. DAC was obtained after the periodate oxidation of nanocrystalline cellulose to form aldehyde groups; then, Fe3O4 nanoparticles were coated with DAC, ... Read more >>

Analyst (The Analyst)
[2020, 145(9):3407-3413]

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An electrochromic supercapacitor based on an MOF derived hierarchical-porous NiO film.

Shengyu Zhou, Shen Wang, Shijin Zhou, Hongbo Xu, Jiupeng Zhao, Jing Wang, Yao Li,

Nickel oxide (NiO) is a promising candidate for future electrochromic supercapacitors due to its pronounced electrical properties and low cost. Unfortunately, the weak interaction between NiO films and conductive substrates results in poor cycling stability. In addition, the long color-switching time and low capacitance by the small lattice spacing in ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(16):8934-8941]

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Role of Pulmonary Embolism Response Team in patients with intermediate- and high-risk pulmonary embolism: a concise review and preliminary experience from China.

Ying Liang, Shao-Ping Nie, Xiao Wang, Ashley Thomas, Elizabeth Thompson, Guan-Qi Zhao, Jing Han, Jing Wang, Mark J D Griffiths,

Intermediate- and high-risk pulmonary embolism (PE) is a life-threatening medical emergency with high morbidity and mortality. Many of the treatment options for PE involve clinicians from multiple disciplines. Pulmonary Embolism Response Teams (PERTs) have been developed to coordinate the multidisciplinary team of clinicians to streamline the decision making process and ... Read more >>

(Journal of geriatric cardiology : JGC)
[2020, 17(8):510-518]

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Omitting ALND Is Not Safe for a Cohort of Early-Stage Breast Cancer Patients with 1-2 SLNs Macro-Metastases and Breast-Conserving Therapy: A Single-Center Retrospective Study.

Xiangyu Wang, Yinqi Gao, Xue Yang, Xiangyi Kong, Zixing Wang, Yi Fang, Jing Wang,

Background:Omitting axillary lymph node dissection (ALND) is recommended for early-stage breast cancer patients with 1-2 sentinel lymph nodes (SLNs) macro-metastases and breast-conserving therapy. However, it is not safe for part of patients, so it is significant to find risk factors and develop a predictive model of non-SLNs metastases in breast ... Read more >>

Iran J Public Health (Iranian journal of public health)
[2020, 49(7):1262-1268]

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Controllable and robust dual-emissive quantum dot nanohybrids as inner filter-based ratiometric probes for visualizable melamine detection.

Jing Wang, Xinyue Liu, Liang Huang, Jiening Jin, Chenxing Jiang, Daquan Li, Huimin Wen, Jun Hu,

The ratiometric fluorescence technique is of great interest due to its visualization characteristics. The construction of a reliable fluorescent ratiometric nanoprobe for high-sensitivity visual quantification is highly sought after but it is limited by poor stability and controllability. Herein, we report a robust dual-emissive quantum dot nanohybrid with precise color ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(7):4562-4572]

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Construction of Lycetin Nanocarriers and Its Effect on the Proliferation and Apoptosis of Hepatocellular Carcinoma Cells by Regulating Nuclear Factor E2 Related Factor/Antioxidant Response Element Pathway.

Ming Jiang, Jing Jin, Xiaohui Ye, Jing Wang, Hongbo Shen, Jie Zhen, Yinong Zhou, Chiba Hiroyuki, K Uberla,

This article explores the role of lysin nanocarriers in inducing apoptosis of human hepatocellular carcinoma cells and the possible molecular mechanisms. Cytotoxicity tests were performed in human fibroblast cell line MRC-5. Anti-cancer activity was tested in liver cancer cell lines HepG2 and HCCLM3. The results show that nanocarriers have a ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2021, 21(2):1054-1060]

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Dietary fiber isolated from sweet potato residues promotes a healthy gut microbiome profile.

Man Liu, Xuezhi Li, Shengmin Zhou, Thomas T Y Wang, Sihan Zhou, Kunlong Yang, Yongxin Li, Jun Tian, Jing Wang,

This study investigated the impact of dietary fiber from sweet potato residue (SPDF) on the diversity of the gut microbiota. An in vitro batch culture system simulating the human gut was used to understand the prebiotic role of SPDF. The results showed that SPDF mediated a significant increase in the ... Read more >>

Food Funct (Food & function)
[2020, 11(1):689-699]

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Yolk-shell structured [email protected]@mSiO2 as a probe for sensing cysteine enantiomers and Cu2+ based on circular dichroism.

Jing Wang, Xu Xu, Xiaolin Qiu, Shuaishuai Zhang, Yinxian Peng,

A yolk-shell structured [email protected]@mSiO2 probe was fabricated by coating a layer of mesoporous silica on the surface of a [email protected] core-shell nanosphere, followed by partially removing the Ag shell. Mirror symmetrical chiral signals at ∼258 nm in the UV region were observed for the probe upon coupling with cysteine enantiomers ... Read more >>

Analyst (The Analyst)
[2019, 144(24):7489-7497]

Cited: 1 time

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Determination of Antimicrobial Resistance of Salmonella in Pork.

Jing Wang, Dan Gu,

Antimicrobial susceptibilities testing is used for evaluating and monitoring the resistance of bacteria to antimicrobial agents. Here we describe three commonly used methods for testing susceptibility to antimicrobial agents in Salmonella, including the disk diffusion method, the broth microdilution method, and the agar dilution method. ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2021, 2182:179-186]

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Association of Glycolipids and Growth Factor Receptors in Lipid Rafts.

Jing Wang, Robert K Yu,

The traditional methods to study lipid rafts and their association with membrane proteins are based mainly on the isolation of a detergent-resistant membrane by biochemical fractionation. However, the use of detergents may induce lipid segregation and/or redistribution of membrane proteins during the process of sample preparation. Here, we describe a ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2021, 2187:131-145]

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A novel tissue engineered nerve graft constructed with autologous vein and nerve microtissue repairs a long-segment sciatic nerve defect.

Jing Wang, Ya-Qiong Zhu, Yu Wang, Hong-Guang Xu, Wen-Jing Xu, Yue-Xiang Wang, Xiao-Qing Cheng, Qi Quan, Yong-Qiang Hu, Chang-Feng Lu, Yan-Xu Zhao, Wen Jiang, Chen Liu, Liang Xiao, Wei Lu, Chen Zhu, Ai-Yuan Wang,

Veins are easy to obtain, have low immunogenicity, and induce a relatively weak inflammatory response. Therefore, veins have the potential to be used as conduits for nerve regeneration. However, because of the presence of venous valves and the great elasticity of the venous wall, the vein is not conducive to ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(1):143-149]

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Controllably facile design of electrophoretic-induced film-forming of nano tungsten oxide (VI) and their anti-wetting functionalization.

Xiaogang Guo, Taotao Liang, Binfang Yuan, Jing Wang, Qi Sun,

There is keen interest for designing promising tungsten oxide (VI, WO3) films or coatings due to their wide applications in fields of energy, engineering, etc. Thus, this paper firstly introduce a novel convenient method of electrophoretic assembly technique (EAT) in an optimal stable suspension of isopropyl alcohol, PEG-1000 and polyethyleneimine ... Read more >>

Nanotechnology (Nanotechnology)
[2020, 31(50):505603]

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Inhibitory Effect of Tetramerized Single-Chain Variable Fragment of Anti-Cyclic Citrullinated Peptide Antibodies on the Proliferation, Activation, and Secretion of Cytokines of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis In Vitro Co-Culture System.

Jing Wang, Ning Tie, Hongbin Li, Xixiong Kang,

Tetramerized single-chain variable fragment (ScFv) of anti-cyclic citrullinated peptide (TeAb-CCP) is a constructed tetramerized ScFv of anti-cyclic citrullinated peptide (CCP) antibodies with p53 tetrameric domain, aim to investigate its effect on fibroblast-like synoviocytes (FLSs) proliferation, migration, invasion, and production of inflammatory mediators in the in vitro co-culture system of peripheral ... Read more >>

Inflammation (Inflammation)
[2020, 43(6):2245-2255]

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Extracting and Selecting Robust Radiomic Features from PET/MR Images in Nasopharyngeal Carcinoma.

Pengfei Yang, Lei Xu, Zuozhen Cao, Yidong Wan, Yi Xue, Yangkang Jiang, Eric Yen, Chen Luo, Jing Wang, Yi Rong, Tianye Niu,

OBJECTIVES:This work aims to study the variation, robustness, and feature redundancy of PET/MR radiomic features in the primary tumor of nasopharyngeal carcinoma (NPC). PROCEDURES:PET/MR scans of 21 NPC patients were used in this study. The primary tumor volumes were defined using PET, T2-weighted-MR (T2-MR), and diffusion-weighted MR (DW-MR) images. A ... Read more >>

Mol Imaging Biol (Molecular imaging and biology)
[2020, 22(6):1581-1591]

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Oxidation of Ryanodine Receptors Promotes Ca2+ Leakage and Contributes to Right Ventricular Dysfunction in Pulmonary Hypertension.

Yongfa Huang, Chuxiang Lei, Wenjun Xie, Li Yan, Yanru Wang, Su Yuan, Jing Wang, Yan Zhao, Zhaojian Wang, Xiaoying Yang, Xiaohan Qin, Quan Fang, Ligang Fang, Xiaoxiao Guo,

Right ventricular (RV) failure is a major cause of death in patients with pulmonary arterial hypertension, and the mechanism of RV failure remains unclear. While the malfunction of RyR2 (ryanodine receptor type 2) on sarcoplasmic reticulum (SR) and aberrant Ca2+ cycling in cardiomyocytes have been recognized in some cardiovascular diseases, ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2020, :HYPERTENSIONAHA12015561]

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Inactivation of the htpsA gene affects capsule development and pathogenicity of Streptococcus suis.

Hua Ni, Min Li, Qiaoqiao Wang, Jing Wang, Xumiao Liu, Feng Zheng, Dan Hu, Xu Yu, Yifang Han, Qi Zhang, Tingting Zhou, Yiwen Wang, Chunhui Wang, Jimin Gao, Zhu-Qing Shao, Xiuzhen Pan,

STREPTOCOCCUS SUIS:serotype 2 (S. suis 2) is an important swine pathogen and also an emerging zoonotic agent. HtpsA has been reported as an immunogenic cell surface protein on the bacterium. In the present study, we constructed an isogenic mutant strain of htpsA, namely ΔhtpsA, to study its role in the ... Read more >>

Virulence (Virulence)
[2020, 11(1):927-940]

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The Influence of Bifidobacterium bifidum and Bacteroides fragilis on Enteric Glial Cell-Derived Neurotrophic Factors and Inflammasome.

Peng-Chun Yang, Xi-Jun Li, Yan-Hua Yang, Wei Qian, Shi-Yu Li, Cai-Hua Yan, Jing Wang, Qin Wang, Xiao-Hua Hou, Chi-Bing Dai,

Enteric glial cells (EGCs) and enteric glial-derived neurotrophic factor (GDNF) are directly involved in intestinal inflammation. In this study, we sought to examine the possible mechanisms for how Bifidobacterium bifidum (B.b.) and Bacteroides fragilis (B.f.) influence EGC regulation. In this study, lipopolysaccharide (LPS) and interferon-γ (IFN-γ) were used as exogenous ... Read more >>

Inflammation (Inflammation)
[2020, 43(6):2166-2177]

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Protocatechuic acid inhibits proliferation, migration and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes.

Huiqiang Wu, Jing Wang, Qing Zhao, Yanjie Ding, Bingyi Zhang, Lingli Kong,

Rheumatoid arthritis (RA) is a chronic joint inflammatory disease that is closely associated with dysregulation of fibroblast-like synoviocytes (FLSs). Protocatechuic acid (PCA), a phenolic compound of anthocyanins, has been proven to possess anti-inflammatory activity. However, the role of PCA in RA has not been investigated. In the present study, we ... Read more >>

Artif Cells Nanomed Biotechnol (Artificial cells, nanomedicine, and biotechnology)
[2020, 48(1):969-976]

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Cordyceps acid alleviates lung cancer in nude mice.

Jing Wang, Hongling Chen, Wanrong Li, Lingling Shan,

The aim of this study is to examine the effect of cordyceps acid (CA) on lung cancer in mice. A lung cancer animal model was established by inoculating lung cancer cells under the armpit of nude mice. The mental state, body weight, and tumor growth of nude mice were recorded ... Read more >>

J Biochem Mol Toxicol (Journal of biochemical and molecular toxicology)
[2020, :e22670]

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Sensitive SERS assay for glyphosate based on the prevention of L-cysteine inhibition of a Au-Pt nanozyme.

Jun Ma, Gege Feng, Ying Ying, Yong Shao, Yongxin She, Lufei Zheng, A M Abd Ei-Aty, Jing Wang,

Herein, an indirect SERS sensing assay was developed for the determination of glyphosate (Gly) in tap water. The mechanism of detection was based on relieving the inhibitory effect of l-cysteine (l-cys) on a Au-Pt nanozyme by combining Gly with l-cys through divalent copper ions (Cu2+). In this method, a novel ... Read more >>

Analyst (The Analyst)
[2020, :]

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