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Author Jing Chen

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Dominant factors of the phosphorus regulatory network differ under various dietary phosphate loads in healthy individuals.

Guoxin Ye, Jiaying Zhang, Zhaori Bi, Weichen Zhang, Minmin Zhang, Qian Zhang, Mengjing Wang, Jing Chen,

<h4>Background</h4>The purpose of this study was to explore the contribution of each factor of the phosphorus metabolism network following phosphorus diet intervention <i>via</i> Granger causality analysis.<h4>Methods</h4>In this study, a total of six healthy male volunteers were enrolled. All participants sequentially received regular, low-, and high-phosphorus diets. Consumption of each diet ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):1076-1086]

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A new metal-organic framework based on rare [Zn4F4] cores for efficient separation of C2H2.

Wen-Juan Shi, Yong-Zhi Li, Jing Chen, Run-Han Su, Lei Hou, Yao-Yu Wang, Zhonghua Zhu,

Assembly <i>via</i> 1,4-benzenedicarboxylate linkers and Zn<sup>2+</sup> ions afforded an MOF containing rare [Zn<sub>4</sub>F<sub>4</sub>] cubane core, showing excellent separation for C<sub>2</sub>H<sub>2</sub>-CO<sub>2</sub> and C<sub>2</sub>H<sub>2</sub>-CH<sub>4</sub> mixtures. Dynamic breakthrough experiments and grand canonical Monte Carlo calculations were carried out to confirm the feasibility of the MOF for the separation application of C<sub>2</sub>H<sub>2</sub>. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(95):12788-12791]

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A Duplex SYBR Green I-based Real-time Polymerase Chain Reaction Assay for Rapid Detection of Canine Kobuvirus and Canine Circovirus

Yang Pan, Jing Chen, Junhuang Wu, Yongxia Wang, Junwei Zou, Ju Yu, Fazhi Xu, Yong Wang,

<h4>Background: </h4> Canine Kobuvirus (CaKoV) and Canine Circovirus (CaCV) are viruses that infect dogs causing diarrheal symptoms that are very similar. However, there is no clinical method to detect a co-infection of these two viruses. <h4>Results: </h4>: In this study, a duplex SYBR Green I-based quantitative real-time polymerase chain reaction ... Read more >>

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Supramolecular assemblies of glycoclusters with aggregation-induced emission for sensitive phenol detection.

Die Li, Jing Chen, Xiaoling Xu, Chunyang Bao, Qiang Zhang,

Supramolecular assemblies with reversible boronate ester linkages are facilely prepared via self-assembly between cyclodextrin-centered glycoclusters and 4,4'-(1,2-diphenylethene-1,2-diyl)bis(1,4-phenylene)diboronic acid (TPEDB). Such sphere-like assemblies have shown a typical aggregation-induced emission (AIE) effect and could act as fluorescent probes for the sensitive detection of phenols in water. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(87):13385-13388]

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Transcription Factor MdWRKY32 Participates in Starch-Sugar Metabolism by Binding to the MdBam5 Promoter in Apples During Postharvest Storage.

Ang Li, Jing Chen, Qiong Lin, Yaoyao Zhao, Yuquan Duan, Su Chit Wai, Congcong Song, Jinfeng Bi,

Starch degradation with fruit ripening is closely related to the aging process and flavor formation in apples. In this study, ethylene, 1-methylcyclopropene (1-MCP), and apples treated at different temperatures were used to determine the key genes of starch-sugar metabolism during storage. Compared with 4 °C storage, 20 °C storage promoted ... Read more >>

J Agric Food Chem (Journal of agricultural and food chemistry)
[2021, :]

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A Summary of Residential Radon Surveys and the Influence of Housing Characteristics on Indoor Radon Levels in Canada.

Jing Chen,

<h4>Abstract</h4>Based on community and nationwide radon surveys with long-term radon measurements in a total of 21,818 homes, radon distribution characteristics in Canada have been reassessed with the population-weighted arithmetic mean radon concentration of 82 Bq m-3, geometric mean radon concentration of 55 Bq m-3, and geometric standard deviation of 2.45. ... Read more >>

Health Phys (Health physics)
[2021, 121(6):574-580]

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Flexible Plasmonic Biosensors for Healthcare Monitoring: Progress and Prospects.

Liping Song, Jing Chen, Ben Bin Xu, Youju Huang,

The noble metal nanoparticle has been widely utilized as a plasmonic unit to enhance biosensors, by leveraging its electric and/or optical properties. Integrated with the "flexible" feature, it further enables opportunities in developing healthcare products in a conformal and adaptive fashion, such as wrist pulse tracers, body temperature trackers, blood ... Read more >>

ACS Nano (ACS nano)
[2021, :]

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Water-Dispersible Gold Nanoclusters: Synthesis Strategies, Optical Properties, and Biological Applications.

Yu Li, Tingting Zhai, Jing Chen, Jiye Shi, Lihua Wang, Jianlei Shen, Xiaoguo Liu,

Atomically precise gold nanoclusters (Au NCs) are an emerging class of quantum-sized nanomaterials. The intrinsic discrete electronic energy levels endowed them with fascinating electronical and optical properties. They have been widely applied in the field of optoelectronics, photovoltaics, catalysis, bio-sensing, bio-imaging and therapeutics. Nevertheless, most Au NCs are synthesized in ... Read more >>

Chemistry (Chemistry (Weinheim an der Bergstrasse, Germany))
[2021, :]

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Emerging highly pathogenic avian influenza (H5N8) virus in migratory birds in Central China, 2020.

Jiasong Xiong, Hao Zhou, Lifang Fan, Gongliang Zhu, Yong Li, Guang Chen, Jun Zhang, Jundong Li, Hesong Zheng, Wei Feng, Jing Chen, Guoxiang Yang, Quanjiao Chen,

Eleven highly pathogenic avian influenza H5N8 viruses (clade 2.3.4.4b) were detected in migratory birds in Central China between November and December 2020, which were highly homologous to strains isolated in Europe from October to December 2020. Phylogenetic analysis indicated that the strains in the study possibly spread from Siberia by ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1503-1506]

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Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF-κB p65 pathway.

Xi-Ding Yang, Zhuo Chen, Ling Ye, Jing Chen, Yong-Yu Yang,

<h4>Context</h4>Esculin, an active coumarin compound, has been demonstrated to exert anti-inflammatory effects. However, its potential role in non-alcoholic steatohepatitis (NASH) remains unclear.<h4>Objective</h4>This study explored the hepatoprotective effect and the molecular mechanism of esculin in methionine choline-deficient (MCD) diet-induced NASH.<h4>Materials and methods</h4>Fifty C57BL/6J mice were divided into five groups: control, model, ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):922-932]

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Non-coding RNAs: New players in mitophagy and neurodegeneration.

Yusi Tai, Jing Chen, Zhouteng Tao, Jin Ren,

Mitophagy controls mitochondrial quality to maintain cellular homeostasis, while aberrations in this process are responsible for neurodegenerative diseases. Mitophagy is initiated through the recruitment of autophagosomes in a ubiquitin-dependent or ubiquitin-independent manner under different stress conditions. Although the detailed molecular mechanisms of how mitophagy processes influence neurodegeneration remain largely uncharacterized, ... Read more >>

Neurochem Int (Neurochemistry international)
[2021, :105253]

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Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages.

Jing Chen, Yi Zhou, Erpeng Zhu, Peng Yang, Mei Li, Shuangxiang Zhang, Jun Yue, Ming Wen, Kaigong Wang, Zhentao Cheng,

<i>Mycoplasma ovipneumoniae (MO)</i> is a principle causative agent of chronic respiratory disease in ruminants, including sheep, goats, and deer, posing a great threat to the ruminant industry worldwide. However, the pathogenesis of <i>MO</i> infection still remains not well understood and needs further clarification. Here we report a time-dependent apoptosis in ... Read more >>

Virulence (Virulence)
[2021, 12(1):2703-2720]

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Clinical features and epidemiological analysis of respiratory human adenovirus infection in hospitalized children: a cross-sectional study in Zhejiang.

Caiyun Wang, Juanjuan Liu, Yumei Mi, Jing Chen, Jing Bi, Yinghu Chen,

<h4>Background</h4>HAdV is one of the common pathogens in hospitalized children with acute respiratory infections (ARIs). We aim to describe the clinical and laboratory features, epidemiological characteristics, and HAdV species and/or types of inpatients with HAdV respiratory infections.<h4>Methods</h4>Respiratory samples were gathered from inpatients diagnosed ARIs in Children's Hospital, Zhejiang University School ... Read more >>

Virol J (Virology journal)
[2021, 18(1):234]

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l-Cysteine-Terminated Triangular Silver Nanoplates/MXene Nanosheets are Used as Electrochemical Biosensors for Efficiently Detecting 5-Hydroxytryptamine.

Jing Chen, Shuying Li, Ying Chen, Jiao Yang, Jianbin Dong, Xiaoquan Lu,

5-Hydroxytryptamine (5-HT) is an important neurotransmitter, and its content in the human body is of great significance to human health. In this study, an l-cysteine-terminated triangular silver nanoplate loaded on a MXene (two-dimensional transition metal carbide or nitride) (Tri-AgNP/l-Cys/MXene) electrochemical sensor was used to detect 5-HT. As an electrically active ... Read more >>

Anal Chem (Analytical chemistry)
[2021, :]

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Amino-functionalized Cu metal-organic framework nanosheets as fluorescent probes for detecting TNP.

Jing Chen, Qian Zhang, Jianbin Dong, Fanghong Xu, Shuying Li,

Here, we report a simple and benign method to successfully fabricate amino-functionalized Cu metal-organic framework (NH<sub>2</sub>-Cu-MOF) nanosheets. After synthesizing Cu<sub>2</sub>O nanocubes, they were mixed with organic ligand 2-aminoterephthalic acid (NH<sub>2</sub>BDC) solution at room temperature for 4 hours to form NH<sub>2</sub>-Cu-MOF nanosheets. Interestingly, the prepared NH<sub>2</sub>-Cu-MOF nanosheets have ultra-thin thickness, directional ... Read more >>

Anal Methods (Analytical methods : advancing methods and applications)
[2021, 13(44):5328-5334]

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A novel propylene glycol alginate gel based colorimetric tube for rapid detection of nitrite in pickled vegetables.

Jing Zhang, Jianfei Yang, Jing Chen, Yuanting Zhu, Kun Hu, Qian Ma, Yong Zuo,

The detection of nitrite is of great significance because it is closely related to food safety. In this work, a rapid colorimetric method was developed for nitrite detection based on the reaction of propylene glycol alginate (PGA) gel interface. In the reaction of nitrite and 4-Aminoacetophenone, diazo compound formed, which ... Read more >>

Food Chem (Food chemistry)
[2021, :131678]

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The association between conventional ultrasound and contrast-enhanced ultrasound appearances and pathological features in small breast cancer.

Rong Wu, Jing Chen, Chun-Xiao Li, Si-Hui Shao, Ming-Hua Yao, Yi-Jin Su,

<h4>Objective</h4>To investigate the association between ultrasound appearances and pathological features in small breast cancer.<h4>Materials and methods</h4>A total of 186 small breast cancers in 186 patients were analyzed in this retrospective study from January 2015 to December 2019 according to pathological results. Forty-seven cases of axillary lymph node metastasis were found. ... Read more >>

Clin Hemorheol Microcirc (Clinical hemorheology and microcirculation)
[2021, :]

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Lipid metabolism disorders effects of 6:2 chlorinated polyfluorinated ether sulfonate through Hsa-miRNA-532-3p/Acyl-CoA oxidase 1(ACOX1) pathway.

Chuanhai Li, Lidan Jiang, Yuan Jin, Donghui Zhang, Jing Chen, Yuan Qi, Rongrong Fan, Jiao Luo, Lin Xu, Wanli Ma, Kunming Zhao, Dianke Yu,

6:2 Chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA), an alternative product of perfluorooctane sulfonate (PFOS), has been frequently detected in various environmental, wildlife, and human samples. A few studies revealed the hepatotoxicity of 6:2 Cl-PFESA in animals, but the underlying toxicity mechanisms remain largely unknown. In this study, we investigated the ... Read more >>

Ecotoxicol Environ Saf (Ecotoxicology and environmental safety)
[2021, 228:113011]

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Involvement of 5f Orbitals in the Covalent Bonding between the Uranyl Ion and Trialkyl Phosphine Oxide: Unraveled by Oxygen K-Edge X-ray Absorption Spectroscopy and Density Functional Theory.

Yusheng Zhang, Wuhua Duan, Yuning Yang, Tian Jian, Yusen Qiao, Guoxi Ren, Nian Zhang, Lei Zheng, Wensheng Yan, Jianchen Wang, Jing Chen, Stefan G Minasian, Taoxiang Sun,

Monodentate organophosphorus ligands have been used for the extraction of the uranyl ion (UO<sub>2</sub><sup>2+</sup>) for over half a century and have exhibited exceptional extractability and selectivity toward the uranyl ion due to the presence of the phosphoryl group (O═P). Tributyl phosphate (TBP) is the extractant of the world-renowned PUREX process, ... Read more >>

Inorg Chem (Inorganic chemistry)
[2021, :]

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Integrative transcriptomic and metabolomic analysis of D-leaf of seven pineapple varieties differing in N-P-K% contents.

Jing Chen, Hui Zeng, Xiumei Zhang,

<h4>Background</h4>Pineapple (Ananas comosus L. Merr.) is the third most important tropical fruit in China. In other crops, farmers can easily judge the nutritional requirements from leaf color. However, concerning pineapple, it is difficult due to the variation in leaf color of the cultivated pineapple varieties. A detailed understanding of the ... Read more >>

BMC Plant Biol (BMC plant biology)
[2021, 21(1):550]

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Insights into the synergy between functional microbes and dissolved oxygen partition in the single-stage partial nitritation-anammox granules system.

Hong Wang, Min Yang, Ke Liu, Enzhe Yang, Jing Chen, Sha Wu, Min Xie, Dongbo Wang, Hengwei Deng, Hong Chen,

The rapid start-up and stable operation of the single-stage partial nitritation-anammox (PNA) process remains a challenge in practical applications. An integrated investigation of nitrogen removal performance, sludge characteristics, activity and abundance, and microbial dynamics was implemented for 360 days via an airlift internal circulation reactor. During long-term operation, the reactor realized ... Read more >>

Bioresour Technol (Bioresource technology)
[2021, :126364]

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The need for pertussis vaccination among older adults and high-risk groups: a perspective from advanced economies of the Asia Pacific region.

Leong Hoe Nam, Cheng-Hsun Chiu, Jung Yeon Heo, Margaret Ip, Ki-Suck Jung, Robert Menzies, Rodney Pearce, Philippe Buchy, Jing Chen, Michael Nissen, Kyu-Bin Oh,

<h4>Introduction</h4>Influenza and pneumococcal vaccines are the most regularly prescribed vaccines amongst adults <65 years of age. Pertussis booster vaccines (available as combined diphtheria-tetanus-acellular pertussis, Tdap) uptake is relatively low in many countries in the Asia-Pacific region. Increasing Tdap vaccination is a strategy that may aid healthy aging.Areas Covered: Epidemiology data, including ... Read more >>

Expert Rev Vaccines (Expert review of vaccines)
[2021, :1-15]

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KDM3A is a Positive Regulator of Cardiac Fibroblasts Conversion that Increases Smad3 Phosphorylation Following TGFβ1 Stimulation

Xiaopei Liu, Zhou Jining, Bofang Zhang, Gen Liu, Qi Hu, Jing Chen,

The epigenetic molecule KDM3A has been shown to be involved in improving cardiovascular diseases, but its effect on cardiac fibroblasts (CFs) remains unclear. Thus, we designed the gain- and loss-of-function experiments to investigate the biological functions of KDM3A in cardiac fibroblasts (CFs). Moreover, we added a SIS3-HCL (a specific inhibitor ... Read more >>

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Association between environmental tobacco smoke exposure in early life and autistic-like behaviors in Chinese preschoolers.

Jian-Hui Yang, Esben Strodl, Chuan-An Wu, Xiao-Na Yin, Guo-Min Wen, Deng-Li Sun, Dan-Xia Xian, Jing-Yi Chen, Ying-Jie Chen, Jing Chen, Wei-Qing Chen,

<h4>Objective</h4>Few studies have evaluated the association between children's exposure to environmental tobacco smoke (ETS) in early life (during pregnancy, from birth to one year and from one to three years) and autistic-like behaviors. This study aimed to explore this association.<h4>Methods</h4>This cross-sectional study analyzed data collected in 2017 as part of ... Read more >>

J Psychosom Res (Journal of psychosomatic research)
[2021, 152:110680]

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Pharmacokinetics, Safety, and Bioequivalence of Two Formulations of Progesterone Soft Capsule in Healthy Chinese Postmenopausal Females: Impact of a High-fat Meal.

Huiling Qin, Liang Zheng, Yuanyuan Fang, Yueyue Liu, Anding Liu, Jinlian Wu, Fengjia Zhu, Jing Chen, Yijun Fan, Wei Hu,

Progesterone is an important natural hormone regulating ovulation and menstruation. The present study aimed to investigate the pharmacokinetics and safety of two formulations of progesterone in Chinese postmenopausal females under fasting and fed conditions. The study adopted a single-dose, open-label, randomized, three-period bioequivalence design. A total of 96 subjects were ... Read more >>

Basic Clin Pharmacol Toxicol (Basic & clinical pharmacology & toxicology)
[2021, :]

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