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A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case-control study.

Xu Chao, Jieqiong Wu, Wei Zhang, Xuesong Feng, Luyan Zhao, Feng Huang, Chao Jiang,

<h4>Background</h4>Hepatocellular carcinoma (HCC) is a common fatal malignant tumor worldwide. STAT4 is HCC susceptibility gene identified by genome-wide association study. The purpose of this study was to determine the association between four candidate single nucleotide polymorphisms (SNPs) in STAT4 genes and HCC risk in Chinese Han population.<h4>Methods</h4>A case-control study was ... Read more >>

Biosci Rep (Bioscience reports)
[2021, :]

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Identification of Novel Biomarkers in Hepatocellular Carcinoma by Integrated Bioinformatical Analysis and Experimental Validation

Chen Liao, Lanlan Wang, Xiaoqiang Li, Jinyu Bai, Jieqiong Wu, Wei Zhang, Hailong Shi, Xuesong Feng, Xu Chao,

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is one of the most common poorly prognosed virulent neoplasms of the digestive system. In this study, we identified novel biomarkers associated with the pathogenesis of HCC aiming to provide new diagnostic and therapeutic approaches for HCC. <h4>Methods: </h4>: Gene expression profiles of GSE62232, GSE84402,GSE121248 ... Read more >>

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ADCY2 rs10059539 C>T polymorphism confers a decreased risk of hepatocellular carcinoma in Chinese Han women.

Xu Chao, Feng Miao, Xuesong Feng, Hailong Shi, Yuewen Wang, Jieqiong Wu, Luyan Zhao, Wei Zhang, Chao Jiang,

<h4>Objective</h4>Hepatocellular carcinoma (HCC) poses a serious threat to human health. ADCY2 gene polymorphisms may be related to HCC susceptibility. Therefore, we investigated whether ADCY2 gene polymorphisms are correlated to the risk of HCC in a Chinese Han population.<h4>Methods</h4>In a case-control study, we examined the associations between single nucleotide polymorphisms (SNPs) ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, :]

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CLGBO: An Algorithm for Constructing Highly Robust Coding Sets for DNA Storage.

Yanfen Zheng, Jieqiong Wu, Bin Wang,

In the era of big data, new storage media are urgently needed because the storage capacity for global data cannot meet the exponential growth of information. Deoxyribonucleic acid (DNA) storage, where primer and address sequences play a crucial role, is one of the most promising storage media because of its ... Read more >>

Front Genet (Frontiers in genetics)
[2021, 12:644945]

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Minimum Free Energy Coding for DNA Storage.

Ben Cao, Xiaokang Zhang, Jieqiong Wu, Bin Wang, Qiang Zhang, Xiaopeng Wei,

With the development of information technology, huge amounts of data are produced at the same time. How to store data efficiently and at low cost has become an urgent problem. DNA is a high-density and persistent medium, making DNA storage a viable solution. In a DNA data storage system, the ... Read more >>

IEEE Trans Nanobioscience (IEEE transactions on nanobioscience)
[2021, 20(2):212-222]

Cited: 4 times

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A Randomized, Double-Blind, Multicenter, Open Phase IV Clinical Trial to Evaluate The Efficacy and Safety of A Chinese Patent Medicine Combined With Mesalazine for Ulcerative Colitis

Lei Zhu, Naizhong Hu, Shunping Ren, Hongpu Sun, Shaofeng Wang, Xianmei Meng, Peimin Feng, Suyun Zhang, Jieqiong Wu, Yangqian Hu, Baisui Zhao, Wenxi Chen, Sumin Zhang, Min Wang, Yaozhou Tian, Jianguo Xiao, Qi Wang, Xiaojun Yang, Hong Shen,

<h4>Background: </h4> Enteric-coated HuDi capsules(HuDi)have been approved for the treatment of ulcerative colitis (UC) in China. In this clinical trial, we objectively evaluated the clinical efficacy and safety of HuDi combined with enteric-coated mesalazine tablets in the treatment of active UC. <h4>Methods: </h4> A total of 355 patients from 18 ... Read more >>

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Effects of biological water purification grid on microbial community of culture environment and intestine of the shrimp Litopenaeus vannamei

Pengbing Pei, Hong Du, Jieqiong Wu, Mingqi Zhong, Qi Lin, Xiaojuan Liu, Yang Chen,

Biological water purification grid (BWPG), a type of biofilm, could increase aquaculture production by improving the growth of shrimp and culture environment. In this study, the microbial community composition and diversity of water, sediment and shrimp intestine were analysed using the Illumina Miseq high‐throughput sequencing technique. Installation of BWPG did ... Read more >>

Aquac Res (Aquaculture research.)
[2019, 50(4):1300-1312]

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The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells.

Xu Chao, Guoquan Wang, Yuping Tang, Changhu Dong, Hong Li, Bin Wang, Jieqiong Wu, Jiarong Zhao,

Peiminine is a compound isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family), which has demonstrated antitumor activities. But its precise molecular mechanism underlying antitumor activity remain elusive. In this study, peiminine-induced apoptosis towards human hepatocellular carcinoma and its molecular mechanism were investigated. MTT assay was employed to assess anticancer effects ... Read more >>

PLoS One (PloS one)
[2019, 14(1):e0201864]

Cited: 3 times

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The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells

Xu Chao, Guoquan Wang, Yuping Tang, Changhu Dong, Hong Li, Bin Wang, Jieqiong Wu, Jiarong Zhao,

Peiminine is a compound that is isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family), which has demonstrated antitumor activities. Its precise molecular mechanisms underlying antitumor activity remain elusive. In this study, peiminine-induced apoptosis towards human hepatocellular carcinoma and its molecular mechanisms were investigated. MTT assay was employed to assess anticancer ... Read more >>

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Computer mouse control device of compound motion mode

DONG MING, YUHUAN ZHU, ZHONGXING ZHOU, JIEQIONG WU, BAIKUN WAN,

The invention belongs to the field of biomedicine and computer technology, in particular to a compound action pattern EEG mouse control device. Aiming at providing a compound action pattern EEG mouse control device which is familiar with a system, has easier control and reduces the occurrence rate of errors so ... Read more >>

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