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Dose-response association of the ZJU index and fatty liver disease risk: A large cohort in China.

Xue Li, Pei Qin, Liming Cao, Yanmei Lou, Jing Shi, Ping Zhao, Changyi Wang, Jianping Ma, Shan Xu, Xiaolin Peng, Hongen Chen, Dan Zhao, Fulan Hu, Yashuang Zhao,

<h4>Aims</h4>To investigate the sex-specific association between the ZJU index and risk of fatty liver disease in a large Chinese cohort.<h4>Methods</h4>Totally 28,729 adults without fatty liver disease at baseline and who completed at least one follow-up of annual examinations between 2009 and 2016 were included in this study. Cox proportional hazards ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2020, :]

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High MTHFR promoter methylation levels in men confer protection against ischemic stroke.

Shan Xu, Qianping Shi, Bo Li, Liyuan Han, Guodong Xu, Xiaolin Peng, Hongen Chen, Shuhong Dai, Wancheng Ma, Changyi Wang, Jianping Ma,

The MTHFR gene encodes methylenetetrahydrofolate reductase required for the metabolism of homocysteine (Hcy) - a previously reported independent risk factor for ischemic stroke (IS). In this study, we first aimed to clarify the association between DNA methylation levels in the MTHFR promoter and the risk of IS, followed by the ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, 20(4):477-486]

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Oral Infection Caused by Non-O1/Non-O139 Vibrio cholerae in a Patient with Esophageal Cancer Undergoing Esophagectomy and Chemoradiotherapy: A Case Report.

Hongxiang Xie, Yuanyuan Wu, Cuiping Liu, Jianzhuang Guo, Jianping Ma, Xiaofeng Li, Xiaojun Sun,

Non-O1/non-O139 <i>Vibrio cholerae</i> (NOVC) are increasingly being recognized as causes of sporadic cases of gastroenteritis and extra-intestinal invasive infections, such as bacteremia as well as skin and wound infections in immunosuppressed hosts. However, oral infections caused by these microorganisms have rarely been reported. We present a case of oral infection ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2020, 13:3923-3927]

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Association of TG/HDLC ratio trajectory and risk of type 2 diabetes: A retrospective cohort study in China.

Yanyan Zhang, Pei Qin, Yanmei Lou, Ping Zhao, Xue Li, Ranran Qie, Xiaoyan Wu, Minghui Han, Shengbing Huang, Yang Zhao, Dechen Liu, Yuying Wu, Yang Li, Xingjin Yang, Yang Zhao, Yifei Feng, Changyi Wang, Jianping Ma, Xiaolin Peng, Hongen Chen, Dan Zhao, Shan Xu, Li Wang, Xinping Luo, Ming Zhang, Dongsheng Hu, Fulan Hu,

<h4>Background</h4>The association of ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C ratio) change trajectory with risk of type 2 diabetes mellitus (T2DM) remains unknown. The aim of this study was to evaluate the association between risk of T2DM and TG/HDL-C ratio change trajectory.<h4>Methods</h4>A total of 18 444 participants aged 18-80 years old ... Read more >>

J Diabetes (Journal of diabetes)
[2020, :]

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Anthocyanins increase serum adiponectin in newly diagnosed diabetes but not in prediabetes: a randomized controlled trial

LiPing Yang, Wenhua Ling, Yun Qiu, Yong Liu, Li Wang, Jing Yang, Changyi Wang, Jianping Ma,

<h4>Background: </h4> Epidemiological studies have suggested that adiponectin is associated with the development of insulin resistance and type 2 diabetes. This study first examined the effect of purified anthocyanins, a group of dietary flavonoids, on serum adiponectin in patients with prediabetes and newly diagnosed diabetes. <h4>Methods: </h4> A total of ... Read more >>

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Effect of Anthocyanins Supplementation on Serum IGFBP-4 Fragments and Glycemic Control in Patients with Fasting Hyperglycemia: A Randomized Controlled Trial.

Liping Yang, Zhaomin Liu, Wenhua Ling, Li Wang, Changyi Wang, Jianping Ma, Xiaolin Peng, Jianying Chen,

<h4>Background</h4>Insulin-like growth factor binding protein-4 (IGFBP-4) fragments have been shown to be associated with cardiometabolic diseases. Anthocyanins as a subgroup of natural polyphenols could have benefits on treating cardiometabolic diseases. The aim of this study was to examine the effects of purified anthocyanins on serum IGFBP-4 fragments and glycemic control ... Read more >>

Diabetes Metab Syndr Obes (Diabetes, metabolic syndrome and obesity : targets and therapy)
[2020, 13:3395-3404]

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Anthocyanins increase serum adiponectin in newly diagnosed diabetes but not in prediabetes: a randomized controlled trial.

Liping Yang, Wenhua Ling, Yun Qiu, Yong Liu, Li Wang, Jing Yang, Changyi Wang, Jianping Ma,

<h4>Background</h4>Epidemiological studies have suggested that adiponectin is associated with the development of insulin resistance and type 2 diabetes. This study first examined the effect of purified anthocyanins, a group of dietary flavonoids, on serum adiponectin in patients with prediabetes and newly diagnosed diabetes.<h4>Methods</h4>A total of 160 patients with prediabetes (n = 90) ... Read more >>

Nutr Metab (Lond) (Nutrition & metabolism)
[2020, 17:78]

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Low-Density Lipoprotein Cholesterol/High-Density Lipoprotein Cholesterol Ratio and Carotid Intima-Media Thickness: A Cohort Study in China.

Pei Qin, Jing Shi, Liming Cao, Xue Li, Yanmei Lou, Changyi Wang, Jianping Ma, Li Wang, Xiaolin Peng, Hongen Chen, Shan Xu, Ping Zhao, Dongsheng Hu, Fulan Hu,

Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C) ratio may carry additional information and has been suggested as a better predictor for atherosclerosis progression and cardiovascular disease (CVD) than LDL-C and HDL-C alone. Therefore, we aim to explore the association between LDL-C/HDL-C ratio and high carotid intima-media thickness (CIMT) risk ... Read more >>

Lipids (Lipids)
[2021, 56(1):59-68]

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The contribution of plasma uric acid to the risk of stroke in hypertensive populations.

Jing Shi, Guanyun Yan, Liming Cao, Xue Li, Yiwei Zhang, Suhua Zhao, Changyi Wang, Jianping Ma, Xiaolin Peng, Hongen Chen, Fulan Hu, Ran Wang,

<h4>Background</h4>There is limited available evidence of a relationship between uric acid (UA) level and stroke in hypertensive populations worldwide. We aimed to estimate the relationship between UA level and stroke in Chinese hypertensive populations.<h4>Methods</h4>A total of 4 710 essentially hypertensive Chinese patients, including 307 with stroke, were recruited consecutively by ... Read more >>

Cardiovasc J Afr (Cardiovascular journal of Africa)
[2020, 31(6):298-303]

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A Comprehensive App That Improves Tuberculosis Treatment Management Through Video-Observed Therapy: Usability Study.

Xujun Guo, Yarui Yang, Howard E Takiff, Minmin Zhu, Jianping Ma, Tao Zhong, Yuzheng Fan, Jian Wang, Shengyuan Liu,

<h4>Background</h4>Treatment of pulmonary tuberculosis (TB) requires at least six months and is compromised by poor adherence. In the directly observed therapy (DOT) scheme recommended by the World Health Organization, the patient is directly observed taking their medications at a health post. An alternative to DOT is video-observed therapy (VOT), in ... Read more >>

JMIR Mhealth Uhealth (JMIR mHealth and uHealth)
[2020, 8(7):e17658]

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Sex-Specific Association of Serum Uric Acid Level and Change in Hyperuricemia Status with Risk of Type 2 Diabetes Mellitus: A Large Cohort Study in China.

Yanmei Lou, Pei Qin, Changyi Wang, Jianping Ma, Xiaolin Peng, Shan Xu, Hongen Chen, Dan Zhao, Li Wang, Dechen Liu, Yang Li, Ping Zhao, Dezhu Han, Dongsheng Hu, Fulan Hu,

Background:Conflicting findings have been reported regarding the sex-specific association between serum uric acid (SUA) level and type 2 diabetes mellitus (T2DM) risk, and no study has explored the association between the change in hyperuricemia status and T2DM risk. The study was aimed at exploring the sex-specific association of baseline SUA ... Read more >>

J Diabetes Res (Journal of diabetes research)
[2020, 2020:9637365]

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Non-O1/non-O139 Vibrio cholerae bacteraemia in mainland China from 2005 to 2019: clinical, epidemiological and genetic characteristics.

Xinyao Li, Yuanyuan Wu, Xiaojun Sun, Jianping Ma, Xiaofeng Li, Cuiping Liu, Hongxiang Xie,

In mainland China, the clinical, epidemiological and genetic features of non-O1/non-O139 Vibrio cholerae (NOVC) bacteraemia have been scarcely investigated. Herein, we describe a patient with NOVC bacteraemia diagnosed in our hospital and present a retrospective analysis of literature reports of 32 other cases in China, detailing the clinical epidemiology, antibiotic ... Read more >>

Epidemiol Infect (Epidemiology and infection)
[2020, 148:e186]

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Macro-aspartate aminotransferase syndrome: a case report.

Hao Mingju, Wang Minyu, Ge Xiaoxiao, Lu Sumei, Ma Jianping, Ma Wanshan,

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, 58(4):e96-e99]

Cited: 1 time

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Dose-response associations between serum creatinine and type 2 diabetes mellitus risk: A Chinese cohort study and meta-analysis of cohort studies.

Pei Qin, Yanmei Lou, Liming Cao, Jing Shi, Gang Tian, Dechen Liu, Qionggui Zhou, Chunmei Guo, Quanman Li, Yang Zhao, Feiyan Liu, Xiaoyan Wu, Ranran Qie, Minghui Han, Shengbing Huang, Ping Zhao, Changyi Wang, Jianping Ma, Xiaolin Peng, Shan Xu, Hongen Chen, Dan Zhao, Ming Zhang, Dongsheng Hu, Fulan Hu,

BACKGROUND:This study aims to investigate the association between serum creatinine and risk of type 2 diabetes mellitus (T2DM) based on a cohort analysis and meta-analysis of cohort studies. METHODS:We enrolled 41 439 participants aged ≥18 years without T2DM at baseline, who had ≥2 health examinations based on an ongoing prospective cohort in ... Read more >>

J Diabetes (Journal of diabetes)
[2020, 12(8):594-604]

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Baseline serum albumin and its dynamic change is associated with type 2 diabetes risk: A large cohort study in China.

Fulan Hu, Yanmei Lou, Jing Shi, Liming Cao, Changyi Wang, Jianping Ma, Xiaolin Peng, Shan Xu, Hongen Chen, Dan Zhao, Yang Zhao, Chunmei Guo, Dechen Liu, Qionggui Zhou, Quanman Li, Feiyan Liu, Gang Tian, Xiaoyan Wu, Ranran Qie, Minghui Han, Shengbing Huang, Ping Zhao, Ming Zhang, Dongsheng Hu, Pei Qin,

BACKGROUND:The study aimed to investigate the associations of baseline serum albumin level and its dynamic change with type 2 diabetes mellitus (T2DM) risk in a large Chinese cohort study. METHODS:This cohort study included 30 442 adults without T2DM at first entry, who completed at least one follow-up of annual examinations between ... Read more >>

Diabetes Metab Res Rev (Diabetes/metabolism research and reviews)
[2020, 36(5):e3296]

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Rational Design of Axially Chiral Platinabinaphthalenes with Aggregation-Induced Emission for Red Circularly Polarized Phosphorescent Organic Light-Emitting Diodes.

Zhiyong Jiang, Jun Wang, Tingting Gao, Jianping Ma, Zhipeng Liu, Runfeng Chen,

Circularly polarized luminescent (CPL) materials have received a lot of interest due to their potential applications in next-generation displays. However, the development of easily accessible red circularly polarized phosphorescent emitters for practical organic light-emitting diodes fabrication remains a grand challenge. In this paper, we report a new family of CPL-active ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(8):9520-9527]

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CpG single nucleotide polymorphisms of the insulin signaling pathway associated with the risk of prediabetic status/type 2 diabetes in Chinese population

Linlin Tang, Changyi Wang, Liyuan Han, Jianping Ma, Jia Cheng, Shiwei Duan,

<h4>Aims: </h4> Cytosine-phosphate-guanine single nucleotide polymorphisms (CpG SNPs) have been identified as new markers in human diseases. We aimed to evaluate the contribution of 29 CpG SNPs in the insulin signaling pathways to the risk of prediabetes and type 2 diabetes (T2D) in Han Chinese. Materials and methods: We recruited ... Read more >>

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Syntheses and characterization of dinuclear and tetranuclear AgI supramolecular complexes generated from symmetric and asymmetric molecular clips containing oxadiazole rings.

Guoxia Jin, Yuqi Ji, Teng Wang, Yanyan Sun, Yulong Li, Guiying Zhu, Jianping Ma,

A new asymmetric ligand, 5-{3-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl}-2-(pyridin-3-yl)-1,3,4-oxadiazole (L5), which contains two oxadiazole rings, was synthesized and characterized. The assembly of symmetric 2,5-bis(pyridin-3-yl)-1,3,4-oxadiazole (L1) and asymmetric L5 with AgCO<sub>2</sub>CF<sub>3</sub> in solution yielded two novel Ag<sup>I</sup> complexes, namely catena-poly[[di-μ-trifluoroacetato-disilver(I)]-bis[μ-2,5-bis(pyridin-3-yl)-1,3,4-oxadiazole]], [Ag<sub>2</sub>(C<sub>2</sub>F<sub>3</sub>O<sub>2</sub>)<sub>2</sub>(C<sub>12</sub>H<sub>8</sub>N<sub>4</sub>O)<sub>2</sub>]<sub>n</sub> or [Ag<sub>2</sub>(μ<sub>2</sub>-O<sub>2</sub>CCF<sub>3</sub>)<sub>2</sub>(L1)<sub>2</sub>]<sub>n</sub> (1), and bis(μ<sub>3</sub>-5-{3-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl}-2-(pyridin-3-yl)-1,3,4-oxadiazole)tetra-μ<sub>3</sub>-trifluoroacetato-tetrasilver(I) dichloromethane monosolvate, [Ag<sub>4</sub>(C<sub>2</sub>F<sub>3</sub>O<sub>2</sub>)<sub>4</sub>(C<sub>22</sub>H<sub>15</sub>N<sub>5</sub>O<sub>2</sub>)<sub>2</sub>]·CH<sub>2</sub>Cl<sub>2</sub> or [Ag<sub>2</sub>(μ<sub>3</sub>-O<sub>2</sub>CCF<sub>3</sub>)<sub>2</sub>(L5)]<sub>2</sub>·CH<sub>2</sub>Cl<sub>2</sub> (2). Complex 1 displays ... Read more >>

Acta Crystallogr C Struct Chem (Acta crystallographica. Section C, Structural chemistry)
[2019, 75(Pt 10):1327-1335]

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Adsorption behaviour of a CdII-triazole MOF for butan-2-one in a single-crystal-to-single-crystal (SCSC) fashion: the role of hydrogen bonding and C-H...π interactions.

Jia Wang, Tianchao You, Teng Wang, Qikui Liu, Jianping Ma, Guoxia Jin,

The adsorption behaviour of the Cd<sup>II</sup>-MOF {[Cd(L)<sub>2</sub>(ClO<sub>4</sub>)<sub>2</sub>]·H<sub>2</sub>O (1), where L is 4-amino-3,5-bis[3-(pyridin-4-yl)phenyl]-1,2,4-triazole, for butan-2-one was investigated in a single-crystal-to-single-crystal (SCSC) fashion. A new host-guest system that encapsulated butan-2-one molecules, namely poly[[bis{μ<sub>3</sub>-4-amino-3,5-bis[3-(pyridin-4-yl)phenyl]-1,2,4-triazole}cadmium(II)] bis(perchlorate) butanone sesquisolvate], {[Cd(C<sub>24</sub>H<sub>18</sub>N<sub>6</sub>)<sub>2</sub>](ClO<sub>4</sub>)<sub>2</sub>·1.5C<sub>4</sub>H<sub>8</sub>O}<sub>n</sub>, denoted C<sub>4</sub>H<sub>8</sub>[email protected] (2), was obtained via an SCSC transformation. MOF 2 crystallizes in the tetragonal ... Read more >>

Acta Crystallogr C Struct Chem (Acta crystallographica. Section C, Structural chemistry)
[2019, 75(Pt 6):806-811]

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Significant Association of Methylenetetrahydrofolate dehydrogenase 1 Promoter Hypomethylation with Stroke in a Chinese Population with Primary Hypertension.

Changyi Wang, Guodong Xu, Qi Wen, Xiaolin Peng, Hongen Chen, Jingwen Zhang, Shan Xu, Chunhui Zhang, Min Zhang, Jianping Ma, Zhaohui Hui, Jianhang Du, Guifu Wu, Min Ma,

OBJECTIVE:Hypertension and hyperhomocysteinemia are both stroke risk factors. Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays a vital role in one-carbon metabolism via encoding a protein with three distinct enzymatic activities (methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formate-tetrahydrofolate ligase). We aimed to elucidate the association between MTHFD1 promoter methylation and stroke in a Chinese ... Read more >>

Ann Clin Lab Sci (Annals of clinical and laboratory science)
[2019, 49(1):112-118]

Cited: 1 time

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CBS promoter hypermethylation increases the risk of hypertension and stroke.

Changyi Wang, Guodong Xu, Qi Wen, Xiaolin Peng, Hongen Chen, Jingwen Zhang, Shan Xu, Chunhui Zhang, Min Zhang, Jianping Ma, Zhaohui Hui, Guifu Wu, Min Ma,

OBJECTIVES:Cystathionine β-synthase is a major enzyme in the metabolism of plasma homocysteine. Hyperhomocysteinemia is positively associated with hypertension and stroke. The present study was performed to examine the possible effects of Cystathionine β-synthase promoter methylation on the development of hypertension and stroke. METHODS:Using quantitative methylation-specific PCR, we determined the Cystathionine ... Read more >>

Clinics (Sao Paulo) (Clinics (Sao Paulo, Brazil))
[2019, 74:e630]

Cited: 4 times

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The effect of the coordination orientation of N atoms on polymeric structures: synthesis and characterization of one- and two-dimensional CuII coordination polymers based on 4-amino-3-(pyridin-2-yl)-5-[(pyridin-3-ylmethyl)sulfanyl]-1,2,4-triazole.

Guiying Zhu, Yang Lu, Guoxia Jin, Xuan Ji, Jianping Ma,

Three new one- (1D) and two-dimensional (2D) Cu<sup>II</sup> coordination polymers, namely poly[[bis{μ<sub>2</sub>-4-amino-3-(pyridin-2-yl)-5-[(pyridin-3-ylmethyl)sulfanyl]-1,2,4-triazole}copper(II)] bis(methanesulfonate) tetrahydrate], {[Cu(C<sub>13</sub>H<sub>12</sub>N<sub>5</sub>S)<sub>2</sub>](CH<sub>3</sub>SO<sub>3</sub>)<sub>2</sub>·4H<sub>2</sub>O}<sub>n</sub> (1), catena-poly[[copper(II)-bis{μ<sub>2</sub>-4-amino-3-(pyridin-2-yl)-5-[(pyridin-4-ylmethyl)sulfanyl]-1,2,4-triazole}] dinitrate methanol disolvate], {[Cu(C<sub>13</sub>H<sub>12</sub>N<sub>5</sub>S)<sub>2</sub>](NO<sub>3</sub>)<sub>2</sub>·2CH<sub>3</sub>OH}<sub>n</sub> (2), and catena-poly[[copper(II)-bis{μ<sub>2</sub>-4-amino-3-(pyridin-2-yl)-5-[(pyridin-4-ylmethyl)sulfanyl]-1,2,4-triazole}] bis(perchlorate) monohydrate], {[Cu(C<sub>13</sub>H<sub>12</sub>N<sub>5</sub>S)<sub>2</sub>](ClO<sub>4</sub>)<sub>2</sub>·H<sub>2</sub>O}<sub>n</sub> (3), were obtained from 4-amino-3-(pyridin-2-yl)-5-[(pyridin-3-ylmethyl)sulfanyl]-1,2,4-triazole with pyridin-3-yl terminal groups and from 4-amino-3-(pyridin-2-yl)-5-[(pyridin-4-ylmethyl)sulfanyl]-1,2,4-triazole with pyridin-4-yl terminal groups. Compound 1 displays a 2D net-like structure. ... Read more >>

Acta Crystallogr C Struct Chem (Acta crystallographica. Section C, Structural chemistry)
[2019, 75(Pt 4):443-450]

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Comparison of coronary heart disease risk assessments among individuals with metabolic syndrome using three diagnostic definitions: a cross-sectional study from China.

Juan Zhou, Qin Gao, Jun Wang, Min Zhang, Jianping Ma, Changyi Wang, Hongen Chen, Xiaolin Peng, Liping Hao,

<h4>Objective</h4>Metabolic syndrome (MetS) is a notable risk factor of coronary heart disease (CHD). However, there are differences in the methods used to define MetS. The purpose of this study was to determine which MetS definition most fully reflects the 10-year probability of CHD based on the Framingham risk algorithm.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Data ... Read more >>

BMJ Open (BMJ open)
[2018, 8(10):e022974]

Cited: 1 time

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HIV/AIDS-related hyponatremia: an old but still serious problem.

Zhanjun Shu, Zimeng Tian, Jinglin Chen, Jianping Ma, Aihemaiti Abudureyimu, Qianqian Qian, Li Zhuo,

Hyponatremia is the most common electrolyte disorder in hospitals. Many medical illnesses, including congestive heart failure, liver failure, renal failure and pneumonia, may be associated with hyponatremia. In addition, hyponatremia in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC) was first reported in 1993. The evidence suggests ... Read more >>

Ren Fail (Renal failure)
[2018, 40(1):68-74]

Cited: 5 times

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TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.

Liang Cheng, Qi Wang, Guangming Li, Riddhima Banga, Jianping Ma, Haisheng Yu, Fumihiko Yasui, Zheng Zhang, Giuseppe Pantaleo, Matthieu Perreau, Sandra Zurawski, Gerard Zurawski, Yves Levy, Lishan Su,

Activation of HIV-1 reservoirs and induction of anti-HIV-1 T cells are critical to control HIV-1 rebound after combined antiretroviral therapy (cART). Here we evaluated in humanized mice (hu-mice) with persistent HIV-1 infection the therapeutic effect of TLR3 agonist and a CD40-targeting HIV-1 vaccine, which consists of a string of 5 ... Read more >>

J Clin Invest (The Journal of clinical investigation)
[2018, 128(10):4387-4396]

Cited: 10 times

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