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Author Jiali Yang

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Molecular pathways underlying tissue injuries in the bladder with ketamine cystitis.

Xiang Xie, Jiayu Liang, Run Huang, Chuang Luo, Jiali Yang, Hongming Xing, Le Zhou, Han Qiao, Erti Ergu, Huan Chen,

Ketamine cystitis (KC) is a chronic bladder inflammation leading to urinary urgency, frequency, and pain. The pathogenesis of KC is complicated and involves multiple tissue injuries in the bladder. Recent studies indicated that urothelium disruption, lamina propria fibrosis and inflammation, microvascular injury, neuropathological alterations, and bladder smooth muscle (BSM) abnormalities ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(7):e21703]

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Efficacy and safety of radiofrequency in the treatment of trigeminal neuralgia: a systematic review and meta-analysis.

Congyang Yan, Qianxi Zhang, Cheng Liu, Jiali Yang, Hu Bian, Jun Zhu, Tongqing Xue,

To assess the effectiveness of radiofrequency (RF) versus other percutaneous strategies (balloon compression, glycerol rhizotomy [GR], and microvascular decompression [MVD]) in patients with trigeminal neuralgia. We systematically searched the electronic databases of PubMed, Embase, and the Cochrane Library to identify eligible studies throughout October 2020. The odds ratio (OR) with ... Read more >>

Acta Neurol Belg (Acta neurologica Belgica)
[2021, :]

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Identification of an immune subtype predicting survival risk and immune activity in hepatocellular carcinoma.

Feng Zhao, Nuo Xu, Jiali Yang, Bo Li, Jianwei Shi, Yuanyuan Zheng, Longjin Xu,

Immune checkpoint inhibitors (ICI) prolong the survival for advanced/metastatic patients with lung cancer or melanoma; however, for hepatocellular carcinoma (HCC) patients, a durable response has not been reported. Herein, we used a total of 719 HCC patients with public genomic data to determine potential prognostic and immunogenic subtypes. The non-negative ... Read more >>

Aging (Albany NY) (Aging)
[2021, 13:]

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Baicalin promotes hippocampal neurogenesis via the Wnt/β-catenin pathway in a chronic unpredictable mild stress-induced mouse model of depression.

Zhigang Xiao, Zhuoqing Cao, Jiali Yang, Zhixia Jia, Yuru Du, Guoqiang Sun, Ye Lu, Lin Pei,

Hippocampal neurogenesis is known to be related to depressive symptoms. Increasing evidence indicates that Wnt/β-catenin signaling regulates multiple aspects of adult hippocampal neurogenesis. Baicalin is a major flavonoid compound with multiple pharmacological effects such as anti-inflammatory, anti-apoptotic, and neuroprotective effects. The current study aimed to explore the antidepressant effects of ... Read more >>

Biochem Pharmacol (Biochemical pharmacology)
[2021, 190:114594]

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TMPRSS4 Promotes Cell Proliferation and Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma by Activating ERK1/2 Signaling Pathway.

Jianyou Gu, Wenjie Huang, Junfeng Zhang, Xianxing Wang, Tian Tao, Ludi Yang, Yao Zheng, Songsong Liu, Jiali Yang, Liwei Zhu, Huaizhi Wang, Yingfang Fan,

Transmembrane protease serine 4 (TMPRSS4) is upregulated in various kinds of human cancers, including pancreatic cancer. However, its biological function in pancreatic ductal adenocarcinoma (PDAC) remains unclear. In the current study, real-time qPCR, immunohistochemical staining, Western blotting, and database (Cancer Genome Atlas and Gene Expression) analysis revealed remarkable overexpression of ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:628353]

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Effect of endothelial glycocalyx on water and LDL transport through the rat abdominal aorta.

Hongyan Kang, Jiali Yang, Weichen Zhang, Jinyan Lu, Xuejiao Ma, Anqiang Sun, Xiaoyan Deng,

The surface of vascular endothelial cells (ECs) is covered by a protective negatively charged layer known as the endothelial glycocalyx. Herein, we hypothesized its transport barrier and mechanosensory role in transmural water flux and low-density lipoprotein (LDL) transport in an isolated rat abdominal aorta perfused under 85 mmHg and 20 dyn/cm<sup>2</sup> ex ... Read more >>

Am J Physiol Heart Circ Physiol (American journal of physiology. Heart and circulatory physiology)
[2021, 320(4):H1724-H1737]

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Synthesis of Fluorescent Carbon Dots and Their Application in Ascorbic Acid Detection.

Tengfei Wang, Hui Luo, Xu Jing, Jiali Yang, Meijun Huo, Yu Wang,

Water-soluble fluorescent carbon dots (CDs) were synthesized by a hydrothermal method using citric acid as the carbon source and ethylenediamine as the nitrogen source. The repeated and scale-up synthetic experiments were carried out to explore the feasibility of macroscopic preparation of CDs. The CDs/Fe<sup>3+</sup> composite was prepared by the interaction ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(5):]

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[Inhibition of Wnt/β-catenin signal and NOX4 impairs repair of silica-induced lung epithelial cell injury].

Jia Ma, Dandan Yang, Jiali Yang, Xiaoming Liu, Qian Cai,

Objective To investigate the effects of the interaction between Wnt/β-catenin signal and NADPH oxidase 4 (NOX4) on the proliferation of pulmonary epithelial cells in response to silica exposure. Methods The airway instillation of silica to C57BL/6 mice was used to produce mouse silicosis models. Immunohistochemistry was used to determine NOX4 ... Read more >>

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology)
[2021, 37(2):132-139]

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Machine-learning radiomics to predict early recurrence in perihilar cholangiocarcinoma after curative resection.

Huan Qin, Xianling Hu, Junfeng Zhang, Haisu Dai, Yonggang He, Zhiping Zhao, Jiali Yang, Zhengrong Xu, Xiaofei Hu, Zhiyu Chen,

<h4>Background and aims</h4>Up to 40%-65% of patients with perihilar cholangiocarcinoma (PHC) rapidly progress to early recurrence (ER) even after curative resection. Quantification of ER risk is difficult and a reliable prognostic prediction tool is absent. We developed and validated a multilevel model, integrating clinicopathology, molecular pathology and radiology, especially radiomics ... Read more >>

Liver Int (Liver international : official journal of the International Association for the Study of the Liver)
[2021, 41(4):837-850]

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The realization of robotic neurorehabilitation in clinical: use of computational intelligence and future prospects analysis.

Jiali Yang, Zhiqi Zhao, Chenzhen Du, Wei Wang, Qin Peng, Juhui Qiu, Guixue Wang,

<b>Introduction</b>: Although there is a need for rehabilitation treatment with the increase in the aging population, the shortage of skilled physicians frustrates this necessity. Robotic technology has been advocated as one of the most viable methods with the potential to replace humans in providing physical rehabilitation of patients with neurological ... Read more >>

Expert Rev Med Devices (Expert review of medical devices)
[2020, 17(12):1311-1322]

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Survival after pulmonary metastasectomy for relapsed osteosarcoma.

Zhenguo Liu, Junqiang Yin, Qian Zhou, Jiali Yang, Bo Zeng, Sai-Ching J Yeung, Jingnan Shen, Chao Cheng,

<h4>Objectives</h4>The purpose of this study was to evaluate the postrelapse survival of relapsed osteosarcoma with pulmonary metastases in patients who received pulmonary metastasectomy using intent to treat and propensity score analysis.<h4>Methods</h4>Patients with osteosarcoma who relapsed with pulmonary metastases between 2004 and 2018 who were treated in a hospital affiliated with ... Read more >>

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2020, :]

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Alteration of tumor-associated macrophage subtypes mediated by KRT6A in pancreatic ductal adenocarcinoma.

Junfeng Zhang, Hui Sun, Songsong Liu, Wenjie Huang, Jianyou Gu, Zhiping Zhao, Huan Qin, Liwen Luo, Jiali Yang, Yongfei Fang, Jiayun Ge, Bing Ni, Huaizhi Wang,

Pancreatic ductal adenocarcinoma (PDAC) is severely affecting the health and lives of patients. Clarifying the composition and regulatory factors of tumor immune microenvironment (TIME) is helpful for the treatment of PDAC. We analyzed the unique TIMEs and gene expression patterns between PDAC and adjacent normal tissue (ANT) using Gene Expression ... Read more >>

Aging (Albany NY) (Aging)
[2020, 12(22):23217-23232]

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Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL.

Zhiping Zhao, Junfeng Zhang, Liangyu Yin, Jiali Yang, Yao Zheng, Mengjie Zhang, Bing Ni, Huaizhi Wang,

Growth and differentiation factor 15 (GDF-15) has been studied as an important hallmark of cancer. However, the receptor of GDF-15 in pancreatic cancer cell remains unclear. Here, we investigated its biological effects in pancreatic ductal adenocarcinoma (PDAC). We found that aberrant GDF-15 expression positively correlated with poor survival of PDAC ... Read more >>

Aging (Albany NY) (Aging)
[2020, 12(22):22564-22581]

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Integration of transcriptome and cistrome analysis identifies RUNX1-target genes involved in pancreatic cancer proliferation.

Songsong Liu, Fuming Xie, Lang Gan, Tao Peng, Xuejun Xu, Shixiang Guo, Wen Fu, Yunchao Wang, Yongsheng Ouyang, Jiali Yang, Xianxing Wang, Yao Zheng, Junfeng Zhang, Huaizhi Wang,

The extremely high proliferation rate of tumor cells contributes to pancreatic cancer (PC) progression. Runt-related transcription factor 1(RUNX1), a key factor in hematopoiesis that was correlated with tumor progression. However, the role of RUNX1 in PC proliferation was still unclear. We found that RUNX1 was significantly upregulated in PC tissues ... Read more >>

Genomics (Genomics)
[2020, 112(6):5343-5355]

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Characterization of the Materials and Techniques of a Birthday Inscribed Lacquer Plaque of the Qing Dynasty

Liping Zheng, Liqin Wang, Xing Zhao, Jiali Yang, Mengxia Zhang, Yunfu Wang,

In this study, in order to analyze the materials and techniques used for the production of the inscribed plaques, multi-analytical scientific approach, including optical microscopy (OM), scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDS), X-ray diffraction (XRD), micro-attenuated total reflection Fourier transform infrared spectroscopy (μ-ATR-FTIR), and micro-Raman spectroscopy (μ-Raman), ... Read more >>

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Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription.

Songsong Liu, Yao Zheng, Yujun Zhang, Junfeng Zhang, Fuming Xie, Shixiang Guo, Jianyou Gu, Jiali Yang, Ping Zheng, Jiejuan Lai, Liangyu Yin, Huaizhi Wang,

<b>Background:</b> Due to the limitations of strategies for its early diagnosis and treatment, pancreatic cancer (PC) remains a substantial human health threat. We previously discovered a methylation-mediated lncRNA, LINC00261, which is downregulated in PC tissues. However, the underlying role of LINC00261 in PC remains largely unknown. <b>Methods:</b> Quantitative real-time PCR ... Read more >>

Theranostics (Theranostics)
[2020, 10(23):10634-10651]

Cited: 4 times

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Development and Feasibility of a Mobile Health-Supported Comprehensive Intervention Model (CIMmH) for Improving the Quality of Life of Patients With Esophageal Cancer After Esophagectomy: Prospective, Single-Arm, Nonrandomized Pilot Study.

Chao Cheng, Rainbow Tin Hung Ho, Yan Guo, Mengting Zhu, Weixiong Yang, Yiran Li, Zhenguo Liu, Shuyu Zhuo, Qi Liang, Zhenghong Chen, Yu Zeng, Jiali Yang, Zhanfei Zhang, Xu Zhang, Aliza Monroe-Wise, Sai-Ching Yeung,

<h4>Background</h4>Patients with esophageal cancer often experience clinically relevant deterioration of quality of life (QOL) after esophagectomy owing to malnutrition, lack of physical exercise, and psychological symptoms.<h4>Objective</h4>This study aimed to evaluate the feasibility, safety, and efficacy of a comprehensive intervention model using a mobile health system (CIMmH) in patients with esophageal ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2020, 22(8):e18946]

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Atherogenic diet-diminished endothelial glycocalyx contributes to impaired vasomotor properties in rat.

Hongyan Kang, Anqiang Sun, Qiuhong Wu, Jiali Yang, Weichen Zhang, Yuxin Qu, Menghan Gao, Xiaoyan Deng,

Hypercholesterolemia- and atherosclerosis-caused vasomotor property dysfunction may be involved in many clinic manifestations of atherosclerosis, including angina, acute myocardial infarction, and sudden cardiac death. However, its underlying mechanism is not clear. The endothelial glycocalyx is a protective surface layer on the endothelial cells, serving as a molecular sieve, cell adhesion ... Read more >>

Am J Physiol Heart Circ Physiol (American journal of physiology. Heart and circulatory physiology)
[2020, 319(4):H814-H823]

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SOMM4mC: a second-order Markov model for DNA N4-methylcytosine site prediction in six species.

Jiali Yang, Kun Lang, Guangle Zhang, Xiaodan Fan, Yuanyuan Chen, Cong Pian,

<h4>Motivation</h4>DNA N4-methylcytosine (4mC) modification is an important epigenetic modification in prokaryotic DNA due to its role in regulating DNA replication and protecting the host DNA against degradation. An efficient algorithm to identify 4mC sites is needed for downstream analyses.<h4>Results</h4>In this study, we propose a new prediction method named SOMM4mC based ... Read more >>

Bioinformatics (Bioinformatics (Oxford, England))
[2020, 36(14):4103-4105]

Cited: 3 times

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Alcohol dehydrogenase modulates quorum sensing in biofilm formations of Acinetobacter baumannii.

Kangjian Zhang, Xiaoyan Yang, Jiali Yang, Xia Qiao, Feng Li, Xiaoming Liu, Jun Wei, Lixin Wang,

Acinetobacter baumannii (A. baumannii) is a common opportunistic nosocomial pathogen, which is able to produce biofilms on the surface of indwelling medical devices, and consequentially causes severe infections in clinical settings. In order to identify genes that involved in the biofilm formation of A. baumannii, the differential expression of genes ... Read more >>

Microb Pathog (Microbial pathogenesis)
[2020, 148:104451]

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Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.

Chao Yuan, Dandan Yang, Jia Ma, Jiali Yang, Jing Xue, Fuyang Song, Xiaoming Liu,

Macrophages play pivotal roles in host defense and immune homeostasis, which have two major functional polarization states, the classically activated M1 and the alternatively activated M2. Interleukin (IL)-17A is an immune modulator able to shape macrophage phenotypes. Wnt/β-catenin is a developmental signaling pathway that plays crucial roles in morphogenesis and ... Read more >>

Braz J Med Biol Res (Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas)
[2020, 53(8):e9488]

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Undetectable circulating tumor DNA levels correlate with low risk of recurrence/metastasis in postoperative pathologic stage I lung adenocarcinoma patients.

Weixiong Yang, Na You, Minghan Jia, Sai-Ching Jim Yeung, Wei Ou, Man Yu, Yinguang Wang, Xiayu Fu, Zhanfei Zhang, Jiali Yang, Zengding Lao, Zhenguo Liu, Bo Zeng, Qiuxiang Ou, Xue Wu, Yang W Shao, Xiaoyu Hong, Siyu Wang, Chao Cheng,

OBJECTIVES:The application of circulating tumor DNA (ctDNA) monitoring after resection in pathologic(p) stage I lung adenocarcinoma (LUAD) patients remains controversial and it is of great clinical interest to decipher the difference of genetic features between ground-glass opacity (GGO) and solid nodules (non-GGO) subgroups. We aim to assess the utility of ... Read more >>

Lung Cancer (Lung cancer (Amsterdam, Netherlands))
[2020, 146:327-334]

Cited: 2 times

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The lncRNA RUNX1-IT1 regulates C-FOS transcription by interacting with RUNX1 in the process of pancreatic cancer proliferation, migration and invasion.

Songsong Liu, Junfeng Zhang, Liangyu Yin, Xianxing Wang, Yao Zheng, Yujun Zhang, Jianyou Gu, Ludi Yang, Jiali Yang, Ping Zheng, Yan Jiang, Ling Shuai, Xiongwei Cai, Huaizhi Wang,

Numerous long noncoding RNAs (lncRNAs) are aberrantly expressed in pancreatic cancer (PC); however, their functions and mechanisms in cancer progression are largely unknown. In this study, we identified a novel PC-associated lncRNA, RUNX1-IT1, that was significantly upregulated in PC patient samples from multiple centers and associated with poor prognosis. In ... Read more >>

Cell Death Dis (Cell death & disease)
[2020, 11(6):412]

Cited: 2 times

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The Use of Values WNR and GNR to Distinguish between and Diagnose Different Types of Pancreatitis.

Liwen Luo, Junfeng Zhang, Jiali Yang, Hongyu Zhang, Yichen Tang, Di Yang, Hui Dong, Yuzhang Wu, Huaizhi Wang, Bing Ni, Zhiqiang Tian,

There is no effective serologic parameter to distinguish different types of pancreatitis now. To distinguish between acute pancreatitis (AP) and acute exacerbations of chronic pancreatitis (CP) and to determine whether fibrosis occurs in CP, we evaluated the ability to produce white blood cells (WBCs), the neutrophil-to-retinol-binding protein (RBP) ratio (called ... Read more >>

Mol Ther Methods Clin Dev (Molecular therapy. Methods & clinical development)
[2020, 18:7-14]

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Detection of toxic methylenecyclopropylglycine and hypoglycin A in litchi aril of three Chinese cultivars.

Jiali Yang, Xiangrong Zhu, Pei Zhang, Yinhong Wang, Yangyang Xiao, Bao Yang, Hongxia Qu, Yueming Jiang,

As a subtropical fruit with high commercial values, litchi is also a source of methylenecyclcopropylglycine (MCPG) and hypoglycin A (HGA), which could cause hypoglycemia and fatal encephalopathy in human. In this work, a quantitative method was developed well to detect MCPG and HGA present in litchi aril of different cultivars. ... Read more >>

Food Chem (Food chemistry)
[2020, 327:127013]

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