Full Text Journal Articles by
Author Jessie E King


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X-linked inhibitor of apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis.

Iyabode O Ajayi, Thomas H Sisson, Peter D R Higgins, Adam J Booth, Rommel L Sagana, Steven K Huang, Eric S White, Jessie E King, Bethany B Moore, Jeffrey C Horowitz,

The accumulation of apoptosis-resistant fibroblasts within fibroblastic foci is a characteristic feature of idiopathic pulmonary fibrosis (IPF), but the mechanisms underlying apoptosis resistance remain unclear. A role for the inhibitor of apoptosis (IAP) protein family member X-linked inhibitor of apoptosis (XIAP) has been suggested by prior studies showing that (1) ... Read more >>

Am J Respir Cell Mol Biol (American journal of respiratory cell and molecular biology)
[2013, 49(1):86-95]

Cited: 39 times

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Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts.

Thomas H Sisson, Toby M Maher, Iyabode O Ajayi, Jessie E King, Peter D R Higgins, Adam J Booth, Rommel L Sagana, Steven K Huang, Eric S White, Bethany B Moore, Jeffrey C Horowitz,

Fibroblasts perform critical functions during the normal host response to tissue injury, but the inappropriate accumulation and persistent activation of these cells results in the development of tissue fibrosis. The mechanisms accounting for the aberrant accumulation of fibroblasts during fibrotic repair are poorly understood, although evidence supports a role for ... Read more >>

Adv Biosci Biotechnol (Advances in bioscience and biotechnology (Print))
[2012, 3(6A):657-664]

Cited: 39 times

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HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

Eliseo A Eugenin, Jessie E King, Avindra Nath, Tina M Calderon, R Suzanne Zukin, Michael V L Bennett, Joan W Berman,

HIV infection of the central nervous system can result in neurologic dysfunction with devastating consequences in AIDS patients. NeuroAIDS is characterized by neuronal injury and loss, yet there is no evidence that HIV can infect neurons. Here we show that the HIV-encoded protein tat triggers formation of a macromolecular complex ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2007, 104(9):3438-3443]

Cited: 128 times

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

Do-Hyung Kim, D D Sarbassov, Siraj M Ali, Jessie E King, Robert R Latek, Hediye Erdjument-Bromage, Paul Tempst, David M Sabatini,

mTOR/RAFT1/FRAP is the target of the immunosuppressive drug rapamycin and the central component of a nutrient- and hormone-sensitive signaling pathway that regulates cell growth. We report that mTOR forms a stoichiometric complex with raptor, an evolutionarily conserved protein with at least two roles in the mTOR pathway. Raptor has a ... Read more >>

Cell (Cell)
[2002, 110(2):163-175]

Cited: 1693 times

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