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Author Jens Figiel

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The German National Case Collection for Familial Pancreatic Carcinoma (FaPaCa)—Knowledge Gained in 20 Years.

Detlef Klaus Bartsch, Elvira Matthäi, Ioannis Mintziras, Christian Bauer, Jens Figiel, Mercede Sina-Boemers, Thomas M Gress, Peter Langer, Emily P Slater,

<h4>Background</h4>Familial pancreatic carcinoma (FPC) is a rare hereditary tumor syndrome with a heterogeneous clinical phenotype. The study of FPC also contributes to a better understanding of the more common sporadic pancreatic ductal adenocarcinoma (PDAC). We report on the past 20 years' experience of the German National Case Collection for Familial ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

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Ruxolitinib for the treatment of SARS-CoV-2 induced acute respiratory distress syndrome (ARDS).

Andreas Neubauer, Thomas Wiesmann, Claus F Vogelmeier, Elisabeth Mack, Chrysanthi Skevaki, Christine Gaik, Christian Keller, Jens Figiel, Kristina Sohlbach, Caroline Rolfes, Harald Renz, Hinnerk Wulf, Andreas Burchert,

Leukemia (Leukemia)
[2020, 34(8):2276-2278]

Cited: 1 time

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Update Regarding Imaging of Neuroendocrine Neoplasms.

Jens Holger Figiel, Simon G Viniol, Jannis Görlach, Anja Rinke, Damiano Librizzi, Andreas H Mahnken,

<h4>Background</h4> Neuroendocrine neoplasms (NEN) are a heterogeneous group of tumors characterized by the expression of typical proteins. A wide range of morphological and functional imaging methods is required in order to adequately assess the course of the disease and to optimally treat the patient. The spectrum of indications ranges from the ... Read more >>

Rofo (RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin)
[2020, 192(2):171-182]

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Cement augmentation of glenoid baseplate screws does not improve primary stability in reversed shoulder arthroplasty: A cadaveric study.

Benjamin Bockmann, Martin Bäumlein, Rainer Koch, Jens Figiel, Philipp Lechler, René Aigner, Christopher Bliemel, Ludwig Oberkircher, Steffen Ruchholtz, Michael Frink,

<h4>Introduction</h4>Cuff tear arthritis and complex proximal humeral fractures are common pathologies that are frequently addressed by the implantation of a reversed shoulder prosthesis. The present cadaveric study aimed to analyze the effect of cement augmentation of the glenoid component on the primary stability in geriatric patients.<h4>Hypothesis</h4>Cement augmentation of glenoid baseplate ... Read more >>

Orthop Traumatol Surg Res (Orthopaedics & traumatology, surgery & research : OTSR)
[2019, 105(2):219-223]

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Incidental findings in pancreas screening programs for high-risk individuals: Results from three European expert centers.

Isaura S Ibrahim, Catharina Brückner, Alfredo Carrato, Julie Earl, Akin Inderson, Wouter H de Vos Tot Nederveen Cappel, Ioannis Mintziras, Elvira Matthäi, Jens Figiel, Martin Wasser, Hans Moreau, Bert Bonsing, Emily P Slater, Detlef K Bartsch, Hans Fa Vasen,

<h4>Background</h4>Widespread abdominal imaging has led to a substantial increase in the detection of incidentalomas. Currently, an increasing number of centers offer surveillance of the pancreas to individuals at high risk (IARs) of pancreatic ductal adenocarcinoma (PDAC).<h4>Objective</h4>The aims of this study were to evaluate the frequency and type of incidental findings ... Read more >>

United European Gastroenterol J (United European gastroenterology journal)
[2019, 7(5):682-688]

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in-situ-approach"-(LISA)-in-a-patient-with-placenta-increta-leading-to-delayed-spontaneous-delivery-of-the-placenta.">"Leaving the placenta in situ approach" (LISA) in a patient with placenta increta leading to delayed spontaneous delivery of the placenta.

Jelena Boekhoff, Birgit Arabin, Jens Figiel, Siegmund Köhler,

<b>Aim:</b> Based on the recent FIGO recommendations, we wish to report on preservation of the uterus in a patient with placenta increta by applying the leaving the placenta <i>in situ</i> approach.<b>Methods:</b> A 30-year-old gravida 2, Para 1 was referred at 25 + 5 gestational weeks due to a placenta previa bipartita increta ... in-situ-approach"-(LISA)-in-a-patient-with-placenta-increta-leading-to-delayed-spontaneous-delivery-of-the-placenta.">Read more >>

J Matern Fetal Neonatal Med (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2020, 33(2):341-343]

Cited: 0 times

in-situ-approach"-(LISA)-in-a-patient-with-placenta-increta-leading-to-delayed-spontaneous-delivery-of-the-placenta.">View full text PDF listing >>



Vascularization of Primary, Peripheral Lung Carcinoma in CEUS - A Retrospective Study (n = 89 Patients).

Hajo Findeisen, Corinna Trenker, Jens Figiel, Brandon H Greene, Konrad Görg, Christian Görg,

<h4>Purpose</h4> To describe the vascularization of peripheral lung carcinoma in CEUS and to compare with B-mode ultrasound (US) and clinical data.<h4>Materials and methods</h4> From April 2004 until September 2015, n = 89 patients with peripheral lung carcinoma were investigated by B-mode US and CEUS. The extent (EE: hypoechoic, hyperechoic), homogeneity (HE: homogeneous, inhomogeneous) and time ... Read more >>

Ultraschall Med (Ultraschall in der Medizin (Stuttgart, Germany : 1980))
[2019, 40(5):603-608]

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Current Technique and Application of Percutaneous Cryotherapy.

Andreas H Mahnken, Alexander Marc König, Jens Holger Figiel,

 Local ablative therapies have become an established treatment option in interventional oncology. Radiofrequency ablation (RFA) and microwave ablation (MWA) are a standard of care in the treatment of hepatocellular carcinoma (HCC). Currently, there is an increasing interest in cryotherapy, one of the oldest ablation techniques. It has some unique characteristics ... Read more >>

Rofo (RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin)
[2018, 190(9):836-846]

Cited: 4 times

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New Task Force Criteria Provide Evolution in Diagnosis of Arrhythmogenic Cardiomyopathy in Patients without Typical Progression of the Disease.

Mariana S Parahuleva, Jens Figiel, Holger Ahrens, Bernhard Schieffer, Dimitar Divchev, Ulrich Lüsebrink,

BACKGROUND The original Task Force Criteria from 1994 for the clinical diagnosis of ARVC were highly specific and based on structural, histological, EKG, and familial features of disease. However, recommendations for clinical diagnosis and management of ARVC are sparse and lacked sensitivity for early disease. CASE REPORT Ventricular electrical instability ... Read more >>

Am J Case Rep (The American journal of case reports)
[2017, 18:299-303]

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Tunnel-enlargement after MPFL reconstruction with a free gracilis graft does correlation with proximal tunnel malposition

Efe Turgay, Almut Höger, Jens Figiel, Philip Roessler, Karl-Friedrich Schüttler, Ali Seif,

<h4>Aims and Objectives:</h4> In current literature only one study investigates femoral tunnel enlargement after medial patello-femoral ligament (MPFL) reconstruction. Aim of the present study was to investigate the occurrence of femoral tunnel enlargement after MPFL reconstruction and a possible correlation to femoral tunnel position as well as clinical outcome. <h4>Materials ... Read more >>

Orthop J Sports Med (Orthopaedic journal of sports medicine)
[2017, 5(4 suppl4):]

Cited: 0 times

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Initial stability of a new cementless fixation method of a tibial component with polyaxial locking screws: a biomechanical in vitro examination.

Christian Benzing, Adrian Skwara, Jens Figiel, Jürgen Paletta,

<h4>Introduction</h4>Cementless fixation of the tibial component is critical as reduced initial stability leads to implant failure. In this experimental in vitro study, a new fixation method of the tibial component using polyaxial locking screws is evaluated using Roentgen stereophotogrammetric analysis (RSA).<h4>Materials and methods</h4>A special prototype of a tibial component with ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2016, 136(9):1309-1316]

Cited: 2 times

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Is there a benefit of proximal locking screws in osteoporotic distal radius fractures? - A biomechanical study.

Benjamin Bockmann, Can Budak, Jens Figiel, Philipp Lechler, Christopher Bliemel, Florian Debus, Tim Schwarting, Ludwig Oberkircher, Michael Frink,

<h4>Introduction</h4>The distal radial fracture is a common fracture and frequently seen in geriatric patients. During the last years, volar plating has become a popular treatment option. While the application of locking screws at the distal fragment is widely accepted, there is no evidence for their use at the radial shaft.<h4>Materials ... Read more >>

Injury (Injury)
[2016, 47(8):1631-1635]

Cited: 0 times

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Wall stress determines systolic and diastolic function--Characteristics of heart failure.

Peter Alter, A Rembert Koczulla, Christoph Nell, Jens H Figiel, Claus F Vogelmeier, Marga B Rominger,

<h4>Introduction</h4>Heart failure can be caused by systolic or diastolic dysfunction. Diagnosing diastolic dysfunction remains challenging, although several criteria have been identified. Ventricular wall stress is crucially involved. It is hypothesized whether increased end-diastolic and end-systolic ventricular wall stress as assessed by the wall stress index is associated with cardiac dysfunction ... Read more >>

Int J Cardiol (International journal of cardiology)
[2016, 202:685-693]

Cited: 12 times

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Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.

Hans Vasen, Isaura Ibrahim, Carmen Guillen Ponce, Emily P Slater, Elvira Matthäi, Alfredo Carrato, Julie Earl, Kristin Robbers, Anneke M van Mil, Thomas Potjer, Bert A Bonsing, Wouter H de Vos Tot Nederveen Cappel, Wilma Bergman, Martin Wasser, Hans Morreau, Günter Klöppel, Christoph Schicker, Martin Steinkamp, Jens Figiel, Irene Esposito, Evelina Mocci, Enrique Vazquez-Sequeiros, Alfonso Sanjuanbenito, Maria Muñoz-Beltran, José Montans, Peter Langer, Volker Fendrich, Detlef K Bartsch,

<h4>Purpose</h4>Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. Hereditary factors play a role in the development of PDAC in 3% to 5% of all patients. Surveillance of high-risk groups, may facilitate detection of PDAC at an early stage. The aim of this study was to assess whether surveillance aids detection ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2016, 34(17):2010-2019]

Cited: 94 times

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Airflow limitation in COPD is associated with increased left ventricular wall stress in coincident heart failure.

Peter Alter, Kirsten van de Sand, Christoph Nell, Jens H Figiel, Timm Greulich, Claus F Vogelmeier, Andreas R Koczulla,

<h4>Background</h4>COPD and heart failure occur with a considerable coincidence. Beside well-known mechanisms of increased right heart load in COPD, dedicated changes of the left ventricle (LV) are ill-defined and the question remains, whether specific interactions exist beyond common shared risk factors.<h4>Methods</h4>LV wall stress was calculated based on cardiac magnetic resonance ... Read more >>

Respir Med (Respiratory medicine)
[2015, 109(9):1131-1137]

Cited: 7 times

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Assessment of right atrium volume by conventional CT or MR techniques: Which modality resembles in vivo reality?

Stephan Rheinheimer, Christina Reh, Jens Figiel, Andreas H Mahnken,

<h4>Purpose</h4>Right atrial volume (RAV) is a prognostic factor of the right heart function. This retrospective study evaluates the comparability of computed tomography (CT) and magnetic resonance imaging (MRI) for right atrial volumetry with conventional planimetric and diametric methods.<h4>Material and methods</h4>29 retrospectively included patients (18 male, 47±12years) underwent CT and 1.5 ... Read more >>

Eur J Radiol (European journal of radiology)
[2016, 85(5):1040-1044]

Cited: 1 time

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MRI following UKA: The component-bone interface.

Dominik Malcherczyk, Jens Figiel, Ulrike Hähnlein, Susanne Fuchs-Winkelmann, Turgay Efe, Thomas J Heyse,

<h4>Background</h4>Loosening is one of the major long-term failure modes in unicondylar knee arthroplasty (UKA). The aim of the study is to describe and characterize implant-bone interface of femoral and tibial components after UKA by means of magnet resonance imaging (MRI).<h4>Material and methods</h4>MRI tailored to reduce metallic artefact of the knee ... Read more >>

Acta Orthop Belg (Acta orthopaedica Belgica)
[2015, 81(1):84-89]

Cited: 2 times

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From Heart Failure to Highly Unsaturated Fatty Acid Deficiency and Vice Versa: Bidirectional Heart and Liver Interactions.

Peter Alter, Tobias Glück, Jens H Figiel, A Rembert Koczulla, Claus F Vogelmeier, Heinz Rupp,

<h4>Background</h4>In several trials, beneficial prognostic effects of highly unsaturated fatty acids (HUFAs) in heart failure were shown. Because other studies showed no incremental benefit in nearly preserved cardiac function, the question arises, whether the degree of cardiac dysfunction is involved. It is hypothesized that increased left ventricular (LV) wall stress ... Read more >>

Can J Cardiol (The Canadian journal of cardiology)
[2016, 32(2):217-225]

Cited: 3 times

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Short-term follow up after implantation of a cell-free collagen type I matrix for the treatment of large cartilage defects of the knee.

Philip P Roessler, Bernhard Pfister, Markus Gesslein, Jens Figiel, Thomas J Heyse, Christian Colcuc, Olaf Lorbach, Turgay Efe, Karl F Schüttler,

<h4>Purpose</h4>Although there are various new scaffold-based techniques for cartilage regeneration it remains unclear up to which defect size they can be used. The present study reports of a cell-free collagen type I gel matrix for the treatment of large cartilage defects of the knee after a two-year follow-up.<h4>Methods</h4>Twenty-eight patients with ... Read more >>

Int Orthop (International orthopaedics)
[2015, 39(12):2473-2479]

Cited: 15 times

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Magnetic resonance-imaging of the effect of targeted antiangiogenic gene delivery in a melanoma tumour model.

Walter Hundt, Silke Steinbach, Dirk Mayer, Mykhaylo Burbelko, Andreas Kiessling, Jens Figiel, Samira Guccione,

<h4>Objectives</h4>We investigated the effect of targeted gene therapy to melanoma tumours (M21) by MR-imaging.<h4>Methods</h4>M21 and M21-L tumours were grown to a size of 850 mm(3). M21 and M21-L tumours were intravenously treated with an αvβ3-integrin-ligand-coupled nanoparticle (RGDNP)/RAF(-) complex five times every 72 hours. MRI was performed at set time intervals ... Read more >>

Eur Radiol (European radiology)
[2015, 25(4):1107-1118]

Cited: 0 times

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Midterm follow-up after implantation of a polyurethane meniscal scaffold for segmental medial meniscus loss: maintenance of good clinical and MRI outcome.

Karl F Schüttler, Felix Haberhauer, Markus Gesslein, Thomas J Heyse, Jens Figiel, Olaf Lorbach, Turgay Efe, Philip P Roessler,

<h4>Purpose</h4>The preservation of meniscal structure and function after segmental meniscal loss is of crucial importance to prevent early development of osteoarthritis. Implantation of artificial meniscal implants has been reported as a feasible treatment option. The purpose of this study was to assess the clinical and magnetic resonance imaging (MRI) results ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2016, 24(5):1478-1484]

Cited: 14 times

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Prognostic value of late gadolinium enhancement in cardiomyopathy: causative risk factor or surrogate marker?

Peter Alter, Jens H Figiel,

Int J Cardiol (International journal of cardiology)
[2015, 180:111-113]

Cited: 2 times

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Management of a metastasized high grade insulinoma (G3) with refractory hypoglycemia: case report and review of the literature.

Michael Scharf, Daniela Mueller, Ute Koenig, Andreas Pfestroff, Wilhelm Nimphius, Jens Figiel, Anja Rinke, Alexander Koenig, Thomas Gress,

Insulinomas represent the most common functional neuroendocrine tumor of the pancreas. They are usually solitary, benign, well differentiated (G1/G2) and curable by surgery. We describe the case of a 45 year old male Caucasian with a unique malignant, metastasized pancreatic insulinoma (Ki 67 of 70%, G3). To control excessive insulin ... Read more >>

Pancreatology (Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.])
[2014, 14(6):542-545]

Cited: 4 times

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MRI after unicondylar knee arthroplasty: rotational alignment of components.

Thomas J Heyse, Jens Figiel, Ulrike Hähnlein, Jan Schmitt, Nina Timmesfeld, Susanne Fuchs-Winkelmann, Turgay Efe,

<h4>Introduction</h4>This pilot study used magnet resonance imaging (MRI) to analyse the rotation of medial unicondylar knee arthroplasty (UKA) components and assessed how accurately the results could be reproduced.<h4>Materials and methods</h4>Knee MRI using a special protocol to reduce metal artefact was performed in ten patients who had undergone medial UKA. Two ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2013, 133(11):1579-1586]

Cited: 6 times

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Height restoration of osteoporotic vertebral compression fractures using different intravertebral reduction devices: a cadaveric study.

Antonio Krüger, Ludwig Oberkircher, Jens Figiel, Felix Floßdorf, Florent Bolzinger, David C Noriega, Steffen Ruchholtz,

<h4>Background</h4>The treatment of osteoporotic vertebral compression fractures using transpedicular cement augmentation has grown significantly during the past two decades. Balloon kyphoplasty was developed to restore vertebral height and improve sagittal alignment. Several studies have shown these theoretical improvements cannot be transferred universally to the clinical setting.<h4>Purpose</h4>The aim of the current ... Read more >>

Spine J (The spine journal : official journal of the North American Spine Society)
[2015, 15(5):1092-1098]

Cited: 24 times

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