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Katy Bell, Jenny Doust, Kevin McGeechan, Andrea R Horvath, Alexandra Barratt, Andrew Hayen, Christopher Semsarian, Les Irwig,

J Hypertens (Journal of hypertension)
[2021, 39(5):1045-1046]

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Benefits and Harms of Hypertension and High-Normal Labels: A Randomized Experiment.

Danielle Marie Muscat, Georgina May Morris, Katy Bell, Erin Cvejic, Jenna Smith, Jesse Jansen, Rae Thomas, Carissa Bonner, Jenny Doust, Kirsten McCaffery,

<h4>Background</h4>Recent US guidelines lowered the threshold for diagnosing hypertension while other international guidelines use alternative/no labels for the same group (blood pressure [BP], <140/90 mm Hg). We investigated potential benefits and harms of hypertension and high-normal BP labels, compared with control, among people at lower risk of cardiovascular disease.<h4>Methods</h4>We conducted ... Read more >>

Circ Cardiovasc Qual Outcomes (Circulation. Cardiovascular quality and outcomes)
[2021, :CIRCOUTCOMES120007160]

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Guidance for the design and reporting of studies evaluating the clinical performance of tests for present or past SARS-CoV-2 infection.

Jenny A Doust, Katy J L Bell, Mariska M G Leeflang, Jacqueline Dinnes, Sally J Lord, Sue Mallett, Janneke H H M van de Wijgert, Sverre Sandberg, Khosrow Adeli, Jonathan J Deeks, Patrick M Bossuyt, Andrea R Horvath,

BMJ (BMJ (Clinical research ed.))
[2021, 372:n568]

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The potential for overdiagnosis and underdiagnosis because of blood pressure variability: a comparison of the 2017 ACC/AHA, 2018 ESC/ESH and 2019 NICE hypertension guidelines.

Katy Bell, Jenny Doust, Kevin McGeechan, Andrea Rita Horvath, Alexandra Barratt, Andrew Hayen, Christopher Semsarian, Les Irwig,

<h4>Objective</h4>To estimate the extent that BP measurement variability may drive over- and underdiagnosis of 'hypertension' when measurements are made according to current guidelines.<h4>Methods</h4>Using data from the National Health and Nutrition Examination Survey and empirical estimates of within-person variability, we simulated annual SBP measurement sets for 1 000 000 patients over 5 years. ... Read more >>

J Hypertens (Journal of hypertension)
[2021, 39(2):236-242]

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Increasing use of CT requested by emergency department physicians in tertiary hospitals in Western Australia 2003-2015: an analysis of linked administrative data.

Susannah Maxwell, Ninh Thi Ha, Max K Bulsara, Jenny Doust, Donald Mcrobbie, Peter O'Leary, John Slavotinek, Rachael Moorin,

<h4>Objective</h4>This study aimed to examine trends in number of CT scans requested by tertiary emergency department (ED) physicians in Western Australia (WA) from 2003 to 2015 across broad demographic and presentation characteristics, anatomical areas and presented symptoms.<h4>Design</h4>An observational cross-sectional study over study period from 2003 to 2015.<h4>Setting</h4>Linked administrative health service ... Read more >>

BMJ Open (BMJ open)
[2021, 11(3):e043315]

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Widening Disease Definitions: What Can Physicians Do?

Jenny A Doust, Julian Treadwell, Katy J L Bell,

Am Fam Physician (American family physician)
[2021, 103(3):138-140]

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Regularity and Continuity of GP Contacts and Use of Statins Amongst People at Risk of Cardiovascular Events.

David Youens, Jenny Doust, Suzanne Robinson, Rachael Moorin,

<h4>Background</h4>Regularity and continuity of general practitioner (GP) contacts are associated with reduced hospitalisation. Opportunities for improved medication management are cited as a potential cause.<h4>Objective</h4>Determine associations between continuity and regularity of primary care and statin use amongst individuals at risk of cardiovascular disease (CVD) outcomes.<h4>Design</h4>Observational cohort study using self-report and administrative ... Read more >>

J Gen Intern Med (Journal of general internal medicine)
[2021, :]

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The effect of taking blood pressure lowering medication at night on cardiovascular disease risk. A systematic review.

Chau L B Ho, Enayet K Chowdhury, Jenny Doust, Mark R Nelson, Christopher M Reid,

To investigate the effect of night-time BP-lowering drug treatment on the risk of major CVD and mortality, we systematically reviewed randomized controlled trials comparing night-time versus morning dosing. Two studies were found relevant to the clinical question (the MAPEC and Hygia trials). They were similar in study design and population ... Read more >>

J Hum Hypertens (Journal of human hypertension)
[2021, :]

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Rates, costs and determinants of lumbar spine imaging in population-based women born in 1973-1978: Data from the Australian Longitudinal Study on Women's Health.

Yuanyuan Wang, Sultana Monira Hussain, Anita E Wluka, Yuan Z Lim, Donna M Urquhart, Gita D Mishra, Helena Teede, Jenny Doust, Wendy J Brown, Flavia M Cicuttini,

<h4>Objective</h4>There are concerns that lumbar spine imaging represents low value care. Our aim was to examine the use of lumbar spine imaging [radiography, computed tomography (CT), magnetic resonance imaging (MRI)] over 20 years, and costs and person-level characteristics of imaging in a large cohort of Australian women.<h4>Methods</h4>The Australian Longitudinal Study ... Read more >>

PLoS One (PloS one)
[2020, 15(12):e0243282]

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Did changes to recommended testing criteria affect the rate of vitamin D testing among Australian women.

Louise Forsyth Wilson, Zhiwei Xu, Gita Devi Mishra, Annette Jane Dobson, Jenny Doust,

We examine whether new government criteria designed to reduce overuse of vitamin D testing changed testing rates in Australian women. Although testing initially declined, the reduction was not sustained. Women who had more doctor visits and who had been tested previously were more likely to have vitamin D testing.<h4>Purpose</h4>Vitamin D ... Read more >>

Arch Osteoporos (Archives of osteoporosis)
[2020, 15(1):162]

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Future directions in cardiovascular disease risk prediction.

Jenny A Doust, Carissa Bonner, Katy JL Bell,

<h4>Background</h4>Although the National Vascular Disease Prevention Alliance (NVDPA) guidelines were published in 2012, many individuals at high risk of cardiovascular disease (CVD) are not prescribed preventive medication or have CVD risk factors recorded. Better use of CVD risk prediction tools and targeting of medication could reduce CVD.<h4>Objective</h4>The aim of this ... Read more >>

Aust J Gen Pract (Australian journal of general practice)
[2020, 49(8):488-494]

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Protocol for a systematic review of qualitative and quantitative effects of cardiovascular disease risk communication using ‘heart age’ concepts

Carissa Bonner, Carys Batcup, Samuel Cornell, Michael Anthony Fajardo, Jenny Doust, Kevin McGeechan, Lyndal Trevena,

<h4>Introduction</h4> The concept of ‘heart age’ is increasingly used for health promotion and alongside clinical guidelines for cardiovascular disease (CVD) prevention. These tools have been used by millions of consumers around the world, and many health organisations promote them as a way of encouraging lifestyle change. However, heart age tools ... Read more >>

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Lack of a significant legacy effect of baseline blood pressure 'treatment naivety' on all-cause and cardiovascular mortality in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

Chau L B Ho, Monique Breslin, Enayet K Chowdhury, Jenny Doust, Christopher M Reid, Barry R Davis, Lara M Simpson, Mark R Nelson,

<h4>Objectives</h4>To investigate legacy effects at 14-year follow-up of all-cause and cardiovascular disease (CVD) mortality in 'treatment-naive' or 'previous treatment' groups based on blood pressure (BP)-lowering treatment status at baseline.<h4>Methods</h4>A post-hoc observational study of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. We excluded participants with a previous history ... Read more >>

J Hypertens (Journal of hypertension)
[2020, 38(3):519-526]

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In patients with hypertension, taking all BP-lowering drugs at bedtime vs in the morning reduced CV events.

Paul Glasziou, Jenny Doust,

Ann Intern Med (Annals of internal medicine)
[2020, 172(6):JC29]

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Trends in knee magnetic resonance imaging, arthroscopies and joint replacements in older Australians: still too much low-value care?

Leon Smith, Alexandra Barratt, Rachelle Buchbinder, Ian A Harris, Jenny Doust, Katy Bell,

<h4>Background</h4>The objective of the study is to describe temporal trends and regional variations in the use of knee magnetic resonance imaging (MRI), knee arthroscopy and total knee replacement surgery in Australians older than 55 years.<h4>Methods</h4>Design: A retrospective descriptive study using routinely collected administrative data.<h4>Main outcome measures</h4>Age-standardized rates of knee MRI, knee ... Read more >>

ANZ J Surg (ANZ journal of surgery)
[2020, 90(5):833-839]

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Impact of a diagnosis of polycystic ovary syndrome on diet, physical activity and contraceptive use in young women: findings from the Australian Longitudinal Study of Women's Health.

Tessa Copp, Erin Cvejic, Kirsten McCaffery, Jolyn Hersch, Jenny Doust, Ben W Mol, Anuja Dokras, Gita Mishra, Jesse Jansen,

STUDY QUESTION:Do diet, physical activity and contraceptive use change after receiving a diagnosis of polycystic ovary syndrome (PCOS)? SUMMARY ANSWER:Using longitudinal data 12 months apart, young women newly diagnosed with PCOS were more likely to stop using contraception but did not change their physical activity or vegetable intake. WHAT IS KNOWN ... Read more >>

Hum Reprod (Human reproduction (Oxford, England))
[2020, 35(2):394-403]

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Legacy effect of delayed blood pressure lowering drug treatment in middle-aged adults with mildly elevated blood pressure: systematic review and meta-analysis.

Chau L B Ho, Sharon Sanders, Monique Breslin, Jenny Doust, Christopher M Reid, Barry R Davis, Lara M Simpson, Frank P Brouwers, Mark R Nelson,

To investigate if there is evidence for a 'legacy effect' for blood pressure (BP) lowering treatment, that is, worse health outcomes from not initiating drug treatment at a systolic BP threshold of 140 mmHg in middle-age adults. We systematically reviewed studies comparing the effects of delayed BP treatment (placebo/untreated during the ... Read more >>

J Hum Hypertens (Journal of human hypertension)
[2020, 34(4):261-270]

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Potential Consequences of Changing Disease Classifications.

Jenny A Doust, Katy J L Bell, Paul P Glasziou,

JAMA (JAMA)
[2020, 323(10):921-922]

Cited: 2 times

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Why We Might Not Need to Stress About Ruling Out Inducible Myocardial Ischemia.

Katy J L Bell, Christopher Semsarian, Jenny Doust,

Ann Intern Med (Annals of internal medicine)
[2020, 172(3):214-215]

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The epidemiology of systematic review updates: a longitudinal study of updating of Cochrane reviews, 2003 to 2018

Hilda Bastian, Jenny Doust, Mike Clarke, Paul Glasziou,

<h4>ABSTRACT</h4> <h4>Background</h4> The Cochrane Collaboration has been publishing systematic reviews in the Cochrane Database of Systematic Reviews ( CDSR ) since 1995, with the intention that these be updated periodically. <h4>Objectives</h4> To chart the long-term updating history of a cohort of Cochrane reviews and the impact on the number of ... Read more >>

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A review of changes to the attention deficit/hyperactivity disorder age of onset criterion using the checklist for modifying disease definitions.

Sharon Sanders, Rae Thomas, Paul Glasziou, Jenny Doust,

BACKGROUND:Widening definitions of health conditions have the potential to affect millions of people and should only occur when there is strong evidence of benefit. In the last version of the Diagnostic and Statistical Manual of Mental Disorders (DSM), the DSM-5 Committee changed the Attention Deficit Hyperactivity Disorder (ADHD) age of ... Read more >>

BMC Psychiatry (BMC psychiatry)
[2019, 19(1):357]

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Is the NHS 'Heart Age Test' too much medicine?

Carissa Bonner, Shannon McKinn, Kirsten McCaffrey, Paul Glasziou, Les Irwig, Jenny Doust, Jesse Jansen, Katy Bell,

Br J Gen Pract (The British journal of general practice : the journal of the Royal College of General Practitioners)
[2019, 69(688):560-561]

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Implementing cardiovascular disease prevention guidelines to translate evidence-based medicine and shared decision making into general practice: theory-based intervention development, qualitative piloting and quantitative feasibility.

Carissa Bonner, Michael Anthony Fajardo, Jenny Doust, Kirsten McCaffery, Lyndal Trevena,

<h4>Background</h4>The use of cardiovascular disease (CVD) prevention guidelines based on absolute risk assessment is poor around the world, including Australia. Behavioural barriers amongst GPs and patients include capability (e.g. difficulty communicating/understanding risk) and motivation (e.g. attitudes towards guidelines/medication). This paper outlines the theory-based development of a website for GP guidelines, ... Read more >>

Implement Sci (Implementation science : IS)
[2019, 14(1):86]

Cited: 2 times

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How have advances in CT dosimetry software impacted estimates of CT radiation dose and cancer incidence? A comparison of CT dosimetry software: Implications for past and future research.

Susannah Maxwell, Richard Fox, Donald McRobbie, Max Bulsara, Jenny Doust, Peter O'Leary, John Slavotinek, John Stubbs, Rachael Moorin,

<h4>Objective</h4>Organ radiation dose from a CT scan, calculated by CT dosimetry software, can be combined with cancer risk data to estimate cancer incidence resulting from CT exposure. We aim to determine to what extent the use of improved anatomical representation of the adult human body "phantom" in CT dosimetry software ... Read more >>

PLoS One (PloS one)
[2019, 14(8):e0217816]

Cited: 1 time

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Shared decision-making about cardiovascular disease medication in older people: a qualitative study of patient experiences in general practice.

Jesse Jansen, Shannon McKinn, Carissa Bonner, Danielle Marie Muscat, Jenny Doust, Kirsten McCaffery,

<h4>Objectives</h4>To explore older people's perspectives and experiences with shared decision-making (SDM) about medication for cardiovascular disease (CVD) prevention.<h4>Design, setting and participants</h4>Semi-structured interviews with 30 general practice patients aged 75 years and older in New South Wales, Australia, who had elevated CVD risk factors (blood pressure, cholesterol) <i>or</i> had received CVD-related ... Read more >>

BMJ Open (BMJ open)
[2019, 9(3):e026342]

Cited: 1 time

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