Full Text Journal Articles by
Author Jennifer Furin

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Access to paediatric formulations for the treatment of childhood tuberculosis.

Madlen Nash, Christophe Perrin, James A Seddon, Jennifer Furin, Janika Hauser, Ben Marais, Ian Kitai, Jeffrey Starke, Lindsay McKenna,

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, 4(12):855-857]

Cited: 0 times

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Drug-Resistant Tuberculosis: A Glance at Progress and Global Challenges.

Khalid M Dousa, Sebastian G Kurz, Charles M Bark, Robert A Bonomo, Jennifer J Furin,

Multidrug-resistant Mycobacterium tuberculosis remains a major public health threat; its management poses a significant economic burden. Treatment requires a programmatic approach with access to laboratory services, second-line medications, and adequate clinical resources. In recent years, we have seen rapid developments in diagnostic techniques with whole genome sequencing-based drug susceptibility prediction ... Read more >>

Infect Dis Clin North Am (Infectious disease clinics of North America)
[2020, 34(4):863-886]

Cited: 0 times

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How COVID-19 could benefit tuberculosis and HIV services in South Africa.

Claire Keene, Erika Mohr-Holland, Tali Cassidy, Vera Scott, Aurelie Nelson, Jennifer Furin, Laura TriviƱo-Duran,

Lancet Respir Med (The Lancet. Respiratory medicine)
[2020, 8(9):844-846]

Cited: 0 times

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Correspondence regarding "Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa".

Erika Mohr-Holland, Anja Reuter, Jennifer Hughes, Johnny Daniels, Busisiwe Beko, Goodman Makhanda, Virginia De Avezedo, Yulene Kock, Helen Cox, Jennifer Furin, Laura Trivino Duran, Petros Isaakidis, Gabriella Ferlazzo,

Eur Respir J (The European respiratory journal)
[2020, 56(1):]

Cited: 0 times

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The problem with vitamin D supplementation for tuberculosis.

Anja Reuter, Jennifer Furin,

Lancet HIV (The lancet. HIV)
[2020, 7(7):e450-e451]

Cited: 0 times

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Clarity with INHindsight: High-Dose Isoniazid for Drug-Resistant Tuberculosis with inhA Mutations.

Sean Wasserman, Jennifer Furin,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2020, 201(11):1331-1333]

Cited: 0 times

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Treating drug-resistant tuberculosis infection: no more excuses.

Anja Reuter, Jennifer Furin,

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

Cited: 0 times

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SARS-CoV-2 infection in a patient on chronic hydroxychloroquine therapy: Implications for prophylaxis.

Khalid M Dousa, Sharad S Malavade, Jennifer Furin, Barbara Gripshover, Marjorie Hatszegi, Leila Hojat, Elie Saade, Robert A Salata,

People exposed to COVID-19 have a risk of developing disease, and health care workers are at risk at a time when they are badly needed during a health care crisis. Hydroxychloroquine and chloroquine have been used as treatment and are being considered as prophylaxis. Our patient developed COVID-19 while on ... Read more >>

IDCases (IDCases)
[2020, 20:e00778]

Cited: 2 times

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Preventing tuberculosis in children: A global health emergency.

Anja Reuter, James A Seddon, Ben J Marais, Jennifer Furin,

It is estimated that 20 million children are exposed to tuberculosis (TB) each year, making TB a global paediatric health emergency. TB preventative efforts have long been overlooked. With the view of achieving "TB elimination" in "our lifetime", this paper explores challenges and potential solutions in the TB prevention cascade, ... Read more >>

Paediatr Respir Rev (Paediatric respiratory reviews)
[2020, 36:44-51]

Cited: 0 times

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Injectable-free regimens containing bedaquiline, delamanid, or both for adolescents with rifampicin-resistant tuberculosis in Khayelitsha, South Africa.

Erika Mohr-Holland, Anja Reuter, Jennifer Furin, Anthony Garcia-Prats, Virginia De Azevedo, Vanessa Mudaly, Yulene Kock, Laura Trivino-Duran, Petros Isaakidis, Jennifer Hughes,

Background:Limited data exist on the use of bedaquiline and delamanid in adolescents with rifampicin-resistant tuberculosis (RR-TB). We describe RR-TB treatment of adolescents (10-19 years) with injectable-free regimens containing these drugs in Khayelitsha, South Africa. Methods:This retrospective study included adolescents initiating injectable-free RR-TB treatment regimens containing bedaquiline and/or delamanid from February ... Read more >>

EClinicalMedicine (EClinicalMedicine)
[2020, 20:100290]

Cited: 0 times

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"A very humiliating illness": a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa.

Jennifer Furin, Marian Loveday, Sindisiwe Hlangu, Lindy Dickson-Hall, Sacha le Roux, Mark Nicol, Helen Cox,

BACKGROUND:Patient-centered care is pillar 1 of the "End TB" strategy, but little has been documented in the literature about what this means for people living with rifampicin-resistant (RR-TB). Optimizing care for such individuals requires a better understanding of the challenges they face and the support they need. METHODS:A qualitative study ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):76]

Cited: 0 times

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Are pretomanid-containing regimens for tuberculosis a victory or a victory narrative?

Lindsay McKenna, Jennifer Furin,

Lancet Respir Med (The Lancet. Respiratory medicine)
[2019, 7(12):999-1000]

Cited: 0 times

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The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis.

Keertan Dheda, Tawanda Gumbo, Gary Maartens, Kelly E Dooley, Megan Murray, Jennifer Furin, Edward A Nardell, Robin M Warren, ,

The Lancet Respiratory Medicine Commission on drug-resistant tuberculosis was published in 2017, which comprehensively reviewed and provided recommendations on various aspects of the disease. Several key new developments regarding drug-resistant tuberculosis are outlined in this Commission Update. The WHO guidelines on treating drug-resistant tuberculosis were updated in 2019 with a ... Read more >>

Lancet Respir Med (The Lancet. Respiratory medicine)
[2019, 7(9):820-826]

Cited: 8 times

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Challenges and controversies in childhood tuberculosis.

Anja Reuter, Jennifer Hughes, Jennifer Furin,

Children bear a substantial burden of suffering when it comes to tuberculosis. Ironically, they are often left out of the scientific and public health advances that have led to important improvements in tuberculosis diagnosis, treatment, and prevention over the past decade. This Series paper describes some of the challenges and ... Read more >>

Lancet (Lancet (London, England))
[2019, 394(10202):967-978]

Cited: 1 time

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Quality of drug-resistant tuberculosis care: Gaps and solutions.

Zarir Udwadia, Jennifer Furin,

Drug-resistant forms of tuberculosis (DR-TB) are a significant cause of global morbidity and mortality and the treatment of DR-TB is characterized by long and toxic regimens that result in low rates of cure. There are few formal studies documenting the quality of DR-TB treatment services provided globally, but the limited ... Read more >>

J Clin Tuberc Other Mycobact Dis (Journal of clinical tuberculosis and other mycobacterial diseases)
[2019, 16:100101]

Cited: 1 time

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The STREAM trial: missed opportunities and lessons for future clinical trials.

Marian Loveday, Anja Reuter, Jennifer Furin, James A Seddon, Helen Cox,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2019, 19(4):351-353]

Cited: 1 time

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Protecting those who serve: are we doing enough to prevent tuberculosis in healthcare workers?

Jennifer Furin, Giovanni Sotgiu,

Eur. Respir. J. (The European respiratory journal)
[2019, 53(4):]

Cited: 0 times

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Building a tuberculosis-free world: The Lancet Commission on tuberculosis.

Michael J A Reid, Nimalan Arinaminpathy, Amy Bloom, Barry R Bloom, Catharina Boehme, Richard Chaisson, Daniel P Chin, Gavin Churchyard, Helen Cox, Lucica Ditiu, Mark Dybul, Jeremy Farrar, Anthony S Fauci, Endalkachew Fekadu, Paula I Fujiwara, Timothy B Hallett, Christy L Hanson, Mark Harrington, Nick Herbert, Philip C Hopewell, Chieko Ikeda, Dean T Jamison, Aamir J Khan, Irene Koek, Nalini Krishnan, Aaron Motsoaledi, Madhukar Pai, Mario C Raviglione, Almaz Sharman, Peter M Small, Soumya Swaminathan, Zelalem Temesgen, Anna Vassall, Nandita Venkatesan, Kitty van Weezenbeek, Gavin Yamey, Bruce D Agins, Sofia Alexandru, Jason R Andrews, Naomi Beyeler, Stela Bivol, Grania Brigden, Adithya Cattamanchi, Danielle Cazabon, Valeriu Crudu, Amrita Daftary, Puneet Dewan, Laurie K Doepel, Robert W Eisinger, Victoria Fan, Sara Fewer, Jennifer Furin, Jeremy D Goldhaber-Fiebert, Gabriela B Gomez, Stephen M Graham, Devesh Gupta, Maureen Kamene, Sunil Khaparde, Eunice W Mailu, Enos O Masini, Lorrie McHugh, Ellen Mitchell, Suerie Moon, Michael Osberg, Tripti Pande, Lea Prince, Kirankumar Rade, Raghuram Rao, Michelle Remme, James A Seddon, Casey Selwyn, Priya Shete, Kuldeep S Sachdeva, Guy Stallworthy, Juan F Vesga, Valentina Vilc, Eric P Goosby,

Lancet (Lancet (London, England))
[2019, 393(10178):1331-1384]

Cited: 42 times

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Healthcare Provider Discrimination toward Pregnant Women with Rifampin-Resistant Tuberculosis.

Marian Loveday, Sindisiwe Hlangu, Jennifer Furin,

Little is known about the treatment experiences of pregnant women with rifampin-resistant tuberculosis. We conducted qualitative interviews with 10 women who had this condition; 9 reported facing discrimination from healthcare providers. Our findings underscore an urgent need to ensure a human-rights-based, patient-centered approach for women with rifampin-resistant tuberculosis who are ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2019, 25(3):609-610]

Cited: 1 time

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A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment.

Malvika Verma, Karan Vishwanath, Feyisope Eweje, Niclas Roxhed, Tyler Grant, Macy Castaneda, Christoph Steiger, Hormoz Mazdiyasni, Taylor Bensel, Daniel Minahan, Vance Soares, John A F Salama, Aaron Lopes, Kaitlyn Hess, Cody Cleveland, Daniel J Fulop, Alison Hayward, Joy Collins, Siddartha M Tamang, Tiffany Hua, Chinonyelum Ikeanyi, Gal Zeidman, Elizabeth Mule, Sooraj Boominathan, Ellena Popova, Jonathan B Miller, Andrew M Bellinger, David Collins, Dalia Leibowitz, Shelly Batra, Sandeep Ahuja, Manju Bajiya, Sonali Batra, Rohit Sarin, Upasna Agarwal, Sunil D Khaparde, Neeraj K Gupta, Deepak Gupta, Anuj K Bhatnagar, Kamal K Chopra, Nandini Sharma, Ashwani Khanna, Jayeeta Chowdhury, Robert Stoner, Alexander H Slocum, Michael J Cima, Jennifer Furin, Robert Langer, Giovanni Traverso,

Multigram drug depot systems for extended drug release could transform our capacity to effectively treat patients across a myriad of diseases. For example, tuberculosis (TB) requires multimonth courses of daily multigram doses for treatment. To address the challenge of prolonged dosing for regimens requiring multigram drug dosing, we developed a ... Read more >>

Sci Transl Med (Science translational medicine)
[2019, 11(483):]

Cited: 2 times

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Treatment Outcomes in Global Systematic Review and Patient Meta-Analysis of Children with Extensively Drug-Resistant Tuberculosis.

Muhammad Osman, Elizabeth P Harausz, Anthony J Garcia-Prats, H Simon Schaaf, Brittany K Moore, Robert M Hicks, Jay Achar, Farhana Amanullah, Pennan Barry, Mercedes Becerra, Domnica I Chiotan, Peter C Drobac, Jennifer Flood, Jennifer Furin, Medea Gegia, Petros Isaakidis, Andrei Mariandyshev, Iveta Ozere, N Sarita Shah, Alena Skrahina, Elena Yablokova, James A Seddon, Anneke C Hesseling, ,

Extensively drug-resistant tuberculosis (XDR TB) has extremely poor treatment outcomes in adults. Limited data are available for children. We report on clinical manifestations, treatment, and outcomes for 37 children (<15 years of age) with bacteriologically confirmed XDR TB in 11 countries. These patients were managed during 1999-2013. For the 37 ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2019, 25(3):441-450]

Cited: 0 times

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Tuberculosis.

Jennifer Furin, Helen Cox, Madhukar Pai,

Tuberculosis remains the leading cause of death from an infectious disease among adults worldwide, with more than 10 million people becoming newly sick from tuberculosis each year. Advances in diagnosis, including the use of rapid molecular testing and whole-genome sequencing in both sputum and non-sputum samples, could change this situation. ... Read more >>

Lancet (Lancet (London, England))
[2019, 393(10181):1642-1656]

Cited: 27 times

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Universal regimens or universal access to drug susceptibility testing for tuberculosis?

Rebecca Acquah, Jennifer Furin,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2019, 19(3):224-225]

Cited: 1 time

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Making the case: developing innovative adherence solutions for the treatment of tuberculosis.

Malvika Verma, Jennifer Furin, Robert Langer, Giovanni Traverso,

BMJ Glob Health (BMJ global health)
[2019, 4(1):e001323]

Cited: 2 times

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Demanding an end to tuberculosis: treatment of tuberculosis infection among persons living with and without HIV.

Justine Fargher, Anja Reuter, Jennifer Furin,

PURPOSE OF REVIEW:More than two billion people are infected with Mycobacterium tuberculosis and few of them are ever offered therapy in spite of such treatment being associated with reduced rates of morbidity and mortality. This article reviews the current recommendations on the diagnosis and treatment of TB infection (or what ... Read more >>

Curr Opin HIV AIDS (Current opinion in HIV and AIDS)
[2019, 14(1):21-27]

Cited: 0 times

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