Full Text Journal Articles by
Author Jennifer Black

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Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial.

Aaron R Weiss, Yen-Lin Chen, Thomas J Scharschmidt, Yueh-Yun Chi, Jing Tian, Jennifer O Black, Jessica L Davis, Julie C Fanburg-Smith, Eduardo Zambrano, James Anderson, Robin Arens, Odion Binitie, Edwin Choy, Justin W Davis, Andrea Hayes-Jordan, Simon C Kao, Mark L Kayton, Sandy Kessel, Ruth Lim, William H Meyer, Lynn Million, Scott H Okuno, Andrew Ostrenga, Marguerite T Parisi, Daniel A Pryma, R Lor Randall, Mark A Rosen, Mary Schlapkohl, Barry L Shulkin, Ethan A Smith, Joel I Sorger, Stephanie Terezakis, Douglas S Hawkins, Sheri L Spunt, Dian Wang,

BACKGROUND:Outcomes for children and adults with advanced soft tissue sarcoma are poor with traditional therapy. We investigated whether the addition of pazopanib to preoperative chemoradiotherapy would improve pathological near complete response rate compared with chemoradiotherapy alone. METHODS:In this joint Children's Oncology Group and NRG Oncology multicentre, randomised, open-label, phase 2 ... Read more >>

Lancet Oncol. (The Lancet. Oncology)
[2020, 21(8):1110-1122]

Cited: 3 times

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Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.

Caroline M Robb, Smit Kour, Jacob I Contreras, Ekta Agarwal, Carter J Barger, Sandeep Rana, Yogesh Sonawane, Beth K Neilsen, Margaret Taylor, Smitha Kizhake, Rhishikesh N Thakare, Sanjib Chowdhury, Jing Wang, Jennifer D Black, Michael A Hollingsworth, Michael G Brattain, Amarnath Natarajan,

[This corrects the article DOI: 10.18632/oncotarget.23749.]. ... Read more >>

Oncotarget (Oncotarget)
[2020, 11(25):2462-2463]

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Lunch on School Days in Canada: Examining Contributions to Nutrient and Food Group Intake and Differences across Eating Locations.

Claire N Tugault-Lafleur, Jennifer L Black,

BACKGROUND:Recent federal proposals in Canada have called for changes in the delivery and funding of school lunches. Yet little evidence has documented the nutritional quality of meals eaten by school children, which is needed to inform school lunch reforms. OBJECTIVES:To assess the dietary contributions of lunch foods to daily food ... Read more >>

J Acad Nutr Diet (Journal of the Academy of Nutrition and Dietetics)
[2020, :]

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Lunch on School Days in Canada: Examining Contributions to Nutrient and Food Group Intakes and Differences Across Eating Locations.

Claire Tugault-Lafleur, Jennifer Black,

AbstractObjectivesRecent federal proposals in Canada have called for changes in the delivery and funding of school lunches. Yet little evidence has documented the nutritional quality of meals eaten by school children needed to inform school lunch reforms. This study assessed the dietary contributions of lunch foods to daily food and ... Read more >>

Curr Dev Nutr (Current developments in nutrition)
[2020, 4(Suppl 2):1497-1497]

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Using an Established Outbreak Response Plan and Molecular Epidemiology Methods in an HIV Transmission Cluster Investigation, Tennessee, January-June 2017.

Lindsey Sizemore, Mary-Margaret Fill, Samantha A Mathieson, Jennifer Black, Meredith Brantley, Kelly Cooper, Joy Garrett, William M Switzer, Philip J Peters, Carolyn Wester,

INTRODUCTION:In April 2017, the Tennessee Department of Health (TDH) was notified of an increase in the number of persons newly diagnosed with HIV in eastern Tennessee in the same month. Two were identified as persons with a history of injection drug use (IDU) and named each other as syringe-sharing partners, ... Read more >>

Public Health Rep (Public health reports (Washington, D.C. : 1974))
[2020, 135(3):329-333]

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Salivary Gland NUT Carcinoma with Prolonged Survival in Children: Case Illustration and Systematic Review of Literature.

Huiying Wang, Vivian L Weiss, Robert D Hoffman, Ty Abel, Richard H Ho, Scott C Borinstein, Kyle Mannion, Julia A Bridge, Jennifer Black, Jiancong Liang,

NUT (midline) carcinoma is a rare, highly aggressive, poorly differentiated carcinoma that characteristically harbors a rearrangement of the NUTM1 gene. Most of these tumors occur in adolescents and young adults, arise from the midline structures of the thorax, head, and neck, and are associated with extremely poor outcomes. Rare cases ... Read more >>

Head Neck Pathol (Head and neck pathology)
[2020, :]

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Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens.

Jennifer Ann Black, Kathryn Crouch, Leandro Lemgruber, Craig Lapsley, Nicholas Dickens, Luiz R O Tosi, Jeremy C Mottram, Richard McCulloch,

Trypanosoma brucei evades mammalian immunity by using recombination to switch its surface-expressed variant surface glycoprotein (VSG), while ensuring that only one of many subtelomeric multigene VSG expression sites are transcribed at a time. DNA repair activities have been implicated in the catalysis of VSG switching by recombination, not transcriptional control. ... Read more >>

Cell Rep (Cell reports)
[2020, 30(3):836-851.e5]

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Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer.

Premila D Leiphrakpam, Audrey J Lazenby, Sanjib Chowdhury, Lynette M Smith, Michelle Mathiesen, Michael G Brattain, Jing Wang, Jennifer D Black, Chandrakanth Are,

BACKGROUND:Na+ /H+ exchanger regulatory factor 1 (NHERF1) has been implicated in the tumorigenesis of several cancer types and is a potential therapeutic target. The current study evaluated the relationship between NHERF1 expression and clinical outcome in colorectal cancer (CRC). METHODS:NHERF1 expression was evaluated by immunohistochemistry in 167 patients with CRC primary ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2020, 121(3):547-560]

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Right to legal capacity in therapeutic jurisprudence: Insights from critical disability theory and the convention on the rights of persons with disabilities.

Anna Arstein-Kerslake, Jennifer Black,

This article addresses whether autonomy is being adequately protected within therapeutic jurisprudence models. It first outlines the history and theory of therapeutic jurisprudence - noting that protection for autonomy has been theorised as a key component of therapeutic jurisprudence. It then examines therapeutic jurisprudence in light of critical disability theory ... Read more >>

Int J Law Psychiatry (International journal of law and psychiatry)
[2020, 68:101535]

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Next-Generation Analysis of Trypanosomatid Genome Stability and Instability.

Emma M Briggs, Catarina A Marques, Joao Reis-Cunha, Jennifer Black, Samantha Campbell, Jeziel Damasceno, Daniella Bartholomeu, Kathryn Crouch, Richard McCulloch,

Understanding the rate and patterns of genome variation is becoming ever more amenable to whole-genome analysis through advances in DNA sequencing, which may, at least in some circumstances, have supplanted more localized analyses by cellular and genetic approaches. Whole-genome analyses can utilize both short- and long-read sequence technologies. Here we ... Read more >>

Methods Mol. Biol. (Methods in molecular biology (Clifton, N.J.))
[2020, 2116:225-262]

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A risk-based treatment strategy for non-rhabdomyosarcoma soft-tissue sarcomas in patients younger than 30 years (ARST0332): a Children's Oncology Group prospective study.

Sheri L Spunt, Lynn Million, Yueh-Yun Chi, James Anderson, Jing Tian, Emily Hibbitts, Cheryl Coffin, M Beth McCarville, R Lor Randall, David M Parham, Jennifer O Black, Simon C Kao, Andrea Hayes-Jordan, Suzanne Wolden, Fran Laurie, Roseanne Speights, Ellen Kawashima, Stephen X Skapek, William Meyer, Alberto S Pappo, Douglas S Hawkins,

BACKGROUND:Tumour grade, tumour size, resection potential, and extent of disease affect outcome in paediatric non-rhabdomyosarcoma soft-tissue sarcoma (NRSTS), but no risk stratification systems exist and the standard of care is poorly defined. We developed a risk stratification system from known prognostic factors and assessed it in the context of risk-adapted ... Read more >>

Lancet Oncol. (The Lancet. Oncology)
[2020, 21(1):145-161]

Cited: 0 times

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Pregnancy Status, Risk Factors, and Opportunities for Referral to Care Among Reproductive-Aged Women With Newly Reported Chronic Hepatitis C Virus Infection in Tennessee.

Cassandra Oliver, Jennifer Black, Shannon De Pont, Lindsey Sizemore, Carolyn Wester,

OBJECTIVES:From 2006 through 2012, the number of acute hepatitis C virus (HCV) infections increased 364% among persons aged ≤30, including reproductive-aged women, in Central Appalachian states. Outreach to reproductive-aged women with newly diagnosed HCV infection affords a unique opportunity to provide counseling, further testing, and linkage to treatment. We modeled ... Read more >>

Public Health Rep (Public health reports (Washington, D.C. : 1974))
[2020, 135(1):90-96]

Cited: 0 times

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Correction: Tugault-Lafleur C.N. and Black J.L. "Differences in the Quantity and Types of Foods and Beverages Consumed by Canadians between 2004 and 2015" Nutrients 2019, 11, 526.

Claire N Tugault-Lafleur, Jennifer L Black,

We would like to submit the following corrections to our recently published paper [...]. ... Read more >>

Nutrients (Nutrients)
[2019, 11(9):]

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Examining differences in school hour and school day dietary quality among Canadian children between 2004 and 2015.

Claire N Tugault-Lafleur, Susan I Barr, Jennifer L Black,

OBJECTIVE:The present study aimed to: (i) evaluate changes in Canadian children's dietary quality during school hours and on school days between 2004 and 2015; and (ii) explore whether changes in dietary quality over time were moderated by sociodemographic characteristics. DESIGN:Nationally representative 24 h dietary recall data were obtained from the ... Read more >>

Public Health Nutr (Public health nutrition)
[2019, 22(16):3051-3062]

Cited: 0 times

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Selective Inhibition of Histone Deacetylases 1/2/6 in Combination with Gemcitabine: A Promising Combination for Pancreatic Cancer Therapy.

Richard S Laschanzky, Lisa E Humphrey, Jihyun Ma, Lynette M Smith, Thomas J Enke, Surendra K Shukla, Aneesha Dasgupta, Pankaj K Singh, Gillian M Howell, Michael G Brattain, Quan P Ly, Adrian R Black, Jennifer D Black,

Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of <10% due in part to a lack of effective therapies. Pan-histone deacetylase (HDAC) inhibitors have shown preclinical efficacy against PDAC but have failed in the clinic due to toxicity. Selective HDAC inhibitors may reduce toxicity while retaining therapeutic efficacy. However, ... Read more >>

Cancers (Basel) (Cancers)
[2019, 11(9):]

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Protocol for a Noninferiority Comparative Effectiveness Trial of Home-Based Palliative Care (HomePal).

Huong Q Nguyen, Richard A Mularski, Paula E Edwards, Joanne Lynn, Mary T Machado, Mary Ann McBurnie, Carmit McMullen, Brian S Mittman, Lynn R Reinke, Ernest Shen, Susan E Wang, Henry S Werch, ,

Introduction: As health care systems strive to meet the growing needs of seriously ill patients with high symptom burden and functional limitations, they need evidence about how best to deliver home-based palliative care (HBPC). We compare a standard HBPC model that includes routine home visits by nurses and prescribing clinicians ... Read more >>

J Palliat Med (Journal of palliative medicine)
[2019, 22(S1):20-33]

Cited: 0 times

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Public Health Surveillance: Electronic Reporting as a Point of Reference.

Jennifer Black, Rachel Hulkower, Walter Suarez, Shreya Patel, Brandon Elliott,

Federal, state, and local laws shape the use of health information for public health purposes, such as the mandated collection of data through electronic disease reporting systems. Health professionals can leverage these data to better anticipate and plan for the needs of communities, which is seen in the use of ... Read more >>

J Law Med Ethics (The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics)
[2019, 47(2_suppl):19-22]

Cited: 0 times

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Retrospective Surveillance of Perinatal Hepatitis C Virus Exposure – Tennessee, 2013-2017.

Heather E. Wingate, Lindsey Sizemore, Jennifer Black, Zachary Heth, Carolyn Wester,

Online J Public Health Inform (Online journal of public health informatics)
[2019, 11(1):]

Cited: 0 times

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Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors.

Jessica L Davis, Christina M Lockwood, Bradley Stohr, Carolin Boecking, Alyaa Al-Ibraheemi, Steven G DuBois, Sara O Vargas, Jennifer O Black, Michael C Cox, Mark Luquette, Brian Turpin, Sara Szabo, Theodore W Laetsch, Catherine M Albert, David M Parham, Douglas S Hawkins, Erin R Rudzinski,

Pediatric mesenchymal tumors harboring variant NTRK fusions (ETV6-negative) are being increasingly described; however, the histologic and clinical features of these variant NTRK tumors and their relationship to classic infantile fibrosarcoma are not well characterized. A better understanding of the clinicopathologic features of these tumors is necessary, and would aid in ... Read more >>

Am. J. Surg. Pathol. (The American journal of surgical pathology)
[2019, 43(4):435-445]

Cited: 3 times

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Correction: A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.

Isabel Z Fernandez, Ryan M Baxter, Josselyn E Garcia-Perez, Elena Vendrame, Thanmayi Ranganath, Daniel S Kong, Karl Lundquist, Tom Nguyen, Sidney Ogolla, Jennifer Black, Csaba Galambos, James C Gumbart, Noor Dawany, Judith R Kelsen, Edwin F de Zoeten, Ralph Quinones, Hesham Eissa, Michael R Verneris, Kathleen E Sullivan, Rosemary Rochford, Catherine A Blish, Ross M Kedl, Cullen M Dutmer, Elena W Y Hsieh,

J. Exp. Med. (The Journal of experimental medicine)
[2019, 216(6):1465]

Cited: 1 time

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Differences in the Quantity and Types of Foods and Beverages Consumed by Canadians between 2004 and 2015.

Claire N Tugault-Lafleur, Jennifer L Black,

This study examined differences in food and beverage intake estimated from nationally representative surveys of Canadians in 2004 and 2015 collected through the Canadian Community Health Surveys. Differences in mean daily energy intake and amounts of food consumed were compared between 2004 and 2015 and across age groups for all ... Read more >>

Nutrients (Nutrients)
[2019, 11(3):]

Cited: 5 times

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Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs.

Charles O Nnadi, Godwin U Ebiloma, Jennifer A Black, Ngozi J Nwodo, Leandro Lemgruber, Thomas J Schmidt, Harry P de Koning,

Treatment of animal African trypanosomiasis (AAT) requires urgent need for safe, potent and affordable drugs and this has necessitated this study. We investigated the trypanocidal activities and mode of action of selected 3-aminosteroids against Trypanosoma brucei brucei. The in vitro activity of selected compounds of this series against T. congolense ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2019, 24(2):]

Cited: 1 time

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Sudden Death due to Complete Airway Obstruction by Bronchial Casts.

Ahmed Gilani, Jennifer O Black, Jason P Weinman, Csaba Galambos,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2019, 199(3):380]

Cited: 0 times

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Assessing exposure to food and beverage advertisements surrounding schools in Vancouver, BC.

Cayley E Velazquez, Madeleine I G Daepp, Jennifer L Black,

Recent policy initiatives call for restricting food marketing to children, yet little is known about children's current exposure to outdoor advertisements. This paper describes the prevalence and characteristics of food- or beverage-related advertisements surrounding 25 public elementary and secondary schools in Vancouver, Canada and assesses whether the informational food environment ... Read more >>

Health Place (Health & place)
[2019, 58:102066]

Cited: 1 time

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The ATR kinase of Trypanosoma brucei links DNA damage signalling and monoallelic control of surface antigen gene expression during antigenic variation

Jennifer Ann Black, Kathryn Crouch, Leandro Lemgruber, Craig Lapsley, Nicholas Dickens, Jeremy Mottram, Richard McCulloch,

Abstract To evade mammalian immunity, Trypanosoma brucei switches the variant surface glycoprotein (VSG) expressed on its surface. Key to this reaction are controls exerted to ensure only one of many subtelomeric multigene VSG expression sites are transcribed at a time. DNA repair activities have to date been implicated only in ... Read more >>

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