Full Text Journal Articles by
Author Janette F Strasburger

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Complex and Novel Arrhythmias Precede Stillbirth in Fetuses With De Novo Long QT Syndrome.

Sarah Strand, Janette F Strasburger, Bettina F Cuneo, Ronald T Wakai,

BACKGROUND:Long QT syndrome (LQTS) is a leading cause of sudden cardiac death in early life and has been implicated in ≈10% of sudden infant deaths and unexplained stillbirths. The purpose of our study was to use fetal magnetocardiography to characterize the electrophysiology and rhythm phenotypes of fetuses with de novo ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2020, 13(5):e008082]

Cited: 0 times

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Predictability in Fetal Supraventricular Tachycardia Management.

Janette F Strasburger,

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 74(7):886-888]

Cited: 0 times

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Low-Cost Fetal Magnetocardiography: A Comparison of Superconducting Quantum Interference Device and Optically Pumped Magnetometers.

Sarah Strand, William Lutter, Janette F Strasburger, Vishal Shah, Oswaldo Baffa, Ronald T Wakai,

Background Fetal magnetocardiography (fMCG) is a highly effective technique for evaluation of fetuses with life-threatening arrhythmia, but its dissemination has been constrained by the high cost and complexity of Superconducting Quantum Interference Device (SQUID) instrumentation. Optically pumped magnetometers (OPMs) are a promising new technology that can replace SQUIDs for many applications. ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2019, 8(16):e013436]

Cited: 0 times

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Fetal magnetocardiogram waveform characteristics.

Sarah A Strand, Janette F Strasburger, Ronald T Wakai,

BACKGROUND:Fetal magnetocardiography (fMCG) is the most direct and precise method of assessing fetal rhythm and conduction. Although the utility of fMCG for evaluation of fetuses with serious arrhythmia is generally acknowledged, many aspects of fetal rhythm and conduction are relatively unstudied. OBJECTIVE:To record fMCG in a large group of normal ... Read more >>

Physiol Meas (Physiological measurement)
[2019, 40(3):035002]

Cited: 0 times

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Detection of Fetal Arrhythmia Using Optically-Pumped Magnetometers.

Margo Batie, Sarah Bitant, Janette F Strasburger, Vishal Shah, Orang Alem, Ronald T Wakai,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(2):284-287]

Cited: 1 time

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Prenatal diagnosis and management of junctional ectopic tachycardia.

S Javed Zaidi, Saad Siddiqui, Bettina F Cuneo, Janette F Strasburger, Robert McDuffie, Ronald T Wakai,

HeartRhythm Case Rep (HeartRhythm case reports)
[2017, 3(11):503-508]

Cited: 0 times

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Electrophysiologic features of fetal ventricular aneurysms and diverticula.

Carli Peters, Annette Wacker-Gussmann, Janette F Strasburger, Bettina F Cuneo, Nina L Gotteiner, Mehemet Gulecyuz, Ronald T Wakai,

Congenital ventricular wall defects are very rare and include congenital ventricular aneurysms (CVAs) and diverticula (CVDs).We report a series of five fetuses: three with CVAs and two with CVDs referred due to fetal arrhythmia. In addition to routine fetal echocardiography, fetal magnetocardiography (fMCG) was used. The literature in CVA and ... Read more >>

Prenat. Diagn. (Prenatal diagnosis)
[2015, 35(2):129-136]

Cited: 6 times

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The natural history of fetal long QT syndrome.

Bettina F Cuneo, Janette F Strasburger, Ronald T Wakai,

Fetal magnetocardiography (fMCG), the magnetic analog of ECG, has provided invaluable insight into the mechanisms of fetal arrhythmias. In the past 15years, we have evaluated over 300 fetuses with arrhythmia by fMCG. We review the unique characteristics and natural history of the long QT syndrome (LQTS) rhythms.We reviewed the fMCGs ... Read more >>

J Electrocardiol (Journal of electrocardiology)
[2016, 49(6):807-813]

Cited: 5 times

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Importance of Fetal Arrhythmias to the Neonatologist and Pediatrician.

Annette Wacker-Gussmann, Ronald T Wakai, Janette F Strasburger,

Sudden, unexplained death during the perinatal period remains a major, longstanding challenge. Recent advances in diagnostic techniques and genetic testing has provided evidence that a significant fraction of these deaths may result from lethal cardiac arrhythmias. In this paper, we review current methods of diagnosing arrhythmia in the fetus and ... Read more >>

Neoreviews (NeoReviews)
[2016, 17(10):e568-e578]

Cited: 0 times

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Fetal Atrial Flutter: Electrophysiology and Associations With Rhythms Involving an Accessory Pathway.

Annette Wacker-Gussmann, Janette F Strasburger, Sharda Srinivasan, Bettina F Cuneo, William Lutter, Ronald T Wakai,

BACKGROUND:Atrial flutter (AFl) accounts for up to one third of all fetal tachyarrhythmias and can result in premature delivery, hydrops, and fetal death in 10% of cases; however, the electrophysiology of AFl in utero is virtually unstudied. METHODS AND RESULTS:In this observational study, we reviewed 19 fetal magnetocardiography studies from ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2016, 5(6):]

Cited: 2 times

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We only find what we look for: fetal heart rate and the diagnosis of long-QT syndrome.

Bettina F Cuneo, Janette F Strasburger,

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2015, 8(4):760-762]

Cited: 2 times

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Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association.

Mary T Donofrio, Anita J Moon-Grady, Lisa K Hornberger, Joshua A Copel, Mark S Sklansky, Alfred Abuhamad, Bettina F Cuneo, James C Huhta, Richard A Jonas, Anita Krishnan, Stephanie Lacey, Wesley Lee, Erik C Michelfelder, Gwen R Rempel, Norman H Silverman, Thomas L Spray, Janette F Strasburger, Wayne Tworetzky, Jack Rychik, ,

BACKGROUND: The goal of this statement is to review available literature and to put forth a scientific statement on the current practice of fetal cardiac medicine, including the diagnosis and management of fetal cardiovascular disease. METHODS AND RESULTS: A writing group appointed by the American Heart Association reviewed the available ... Read more >>

Circulation (Circulation)
[2014, 129(21):2183-2242]

Cited: 183 times

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Diagnosis and treatment of fetal arrhythmia.

Annette Wacker-Gussmann, Janette F Strasburger, Bettina F Cuneo, Ronald T Wakai,

Detection and careful stratification of fetal heart rate (FHR) is extremely important in all pregnancies. The most lethal cardiac rhythm disturbances occur during apparently normal pregnancies where FHR and rhythm are regular and within normal or low-normal ranges. These hidden depolarization and repolarization abnormalities, associated with genetic ion channelopathies cannot ... Read more >>

Am J Perinatol (American journal of perinatology)
[2014, 31(7):617-628]

Cited: 14 times

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Fetal arrhythmias associated with cardiac rhabdomyomas.

Annette Wacker-Gussmann, Janette F Strasburger, Bettin F Cuneo, Delonia L Wiggins, Nina L Gotteiner, Ronald T Wakai,

Primary heart tumors in fetuses are rare and mainly represent rhabdomyomas. The tumors have a variable expression and can be associated with arrhythmias, including both wide and narrow QRS tachycardia. Although multiple Doppler techniques exist to assess fetal heart rhythm, it can be difficult to record precise electrophysiological abnormalities in ... Read more >>

Heart Rhythm (Heart rhythm)
[2014, 11(4):677-683]

Cited: 7 times

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In utero diagnosis of long QT syndrome by magnetocardiography.

Bettina F Cuneo, Janette F Strasburger, Suhong Yu, Hitoshi Horigome, Takayoshi Hosono, Akihiko Kandori, Ronald T Wakai,

The electrophysiology of long QT syndrome (LQTS) in utero is virtually unstudied. Our goal here was to evaluate the efficacy of fetal magnetocardiography (fMCG) for diagnosis and prognosis of fetuses at risk of LQTS.We reviewed the pre/postnatal medical records of 30 fetuses referred for fMCG because of a family history ... Read more >>

Circulation (Circulation)
[2013, 128(20):2183-2191]

Cited: 27 times

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Magnetophysiologic and echocardiographic comparison of blocked atrial bigeminy and 2:1 atrioventricular block in the fetus.

Delonia L Wiggins, Janette F Strasburger, Nina L Gotteiner, Bettina Cuneo, Ronald T Wakai,

BACKGROUND:Blocked atrial bigeminy (BAB) and second-degree atrioventricular block with 2:1 conduction block (2:1 AVB) both present as ventricular bradycardia and can be difficult to distinguish by echocardiography. Since the prognosis and clinical management of these rhythms are different, an accurate diagnosis is essential. OBJECTIVE:To identify magnetic and mechanical heart rate ... Read more >>

Heart Rhythm (Heart rhythm)
[2013, 10(8):1192-1198]

Cited: 10 times

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Independent component analysis of normal and abnormal rhythm in twin pregnancies.

Nana Aba Mensah-Brown, William J Lutter, Silvia Comani, Janette F Strasburger, Ronald T Wakai,

We investigated the utility of ICA for evaluation of fetal rhythm in five uncomplicated twin pregnancies and in five twin pregnancies complicated by fetal arrhythmia. Using objective and subjective criteria, we sought to determine how the signal-to-noise ratio, signal fidelity and interference rejection are affected when synthesizing the fetal signal ... Read more >>

Physiol Meas (Physiological measurement)
[2011, 32(1):51-64]

Cited: 2 times

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Fetal cardiac arrhythmia detection and in utero therapy.

Janette F Strasburger, Ronald T Wakai,

The human fetal heart develops arrhythmias and conduction disturbances in response to ischemia, inflammation, electrolyte disturbances, altered load states, structural defects, inherited genetic conditions, and many other causes. Yet sinus rhythm is present without altered rate or rhythm in some of the most serious electrophysiological diseases, which makes detection of ... Read more >>

Nat Rev Cardiol (Nature reviews. Cardiology)
[2010, 7(5):277-290]

Cited: 38 times

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Assessment of left ventricular pre-ejection period in the fetus using simultaneous magnetocardiography and echocardiography.

Nana Aba Mensah-Brown, Ronald T Wakai, Bageshree Cheulkar, Shardha Srinivasan, Janette F Strasburger,

Fetal magnetocardiography (fMCG) is a promising new technique for assessing fetal rhythm; however, no prior studies have utilized fMCG to evaluate human fetal electromechanical physiology. Pre-ejection period (PEP) is an important measure of the electromechanical activation of the heart, and is altered by disease states and arrhythmias.A novel technique was ... Read more >>

Fetal. Diagn. Ther. (Fetal diagnosis and therapy)
[2010, 28(3):167-174]

Cited: 9 times

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Meeting the research infrastructure needs of micropolitan and rural communities.

Janette F Strasburger,

In the 1800s, this country chose to establish land-grant colleges to see that the working class could attain higher education, and that the research needs of the agricultural and manufacturing segments of this country could be met. It seems contrary to our origins to see so little support at present ... Read more >>

WMJ (WMJ : official publication of the State Medical Society of Wisconsin)
[2009, 108(3):133-138]

Cited: 1 time

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An expanded phenotype of maternal SSA/SSB antibody-associated fetal cardiac disease.

Bettina F Cuneo, Janette F Strasburger, Alisa Niksch, Marc Ovadia, Ronald T Wakai,

Conventional manifestations of fetal Sjogren's antibodies (SSA/SSB) associated cardiac disease include atrioventricular block (AVB), transient sinus bradycardia, endocardial fibroelastosis (EFE) and dilated cardiomyopathy. We describe other manifestations of cardiac disease.We describe three fetuses with unique myocardial and conduction system disease.One had isolated EFE with subsequent mitral and tricuspid valve chordal ... Read more >>

J. Matern. Fetal. Neonatal. Med. (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2009, 22(3):233-238]

Cited: 18 times

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Magnetocardiography for fetal arrhythmias.

Janette F Strasburger, Bageshree Cheulkar, Ronald T Wakai,

Heart Rhythm (Heart rhythm)
[2008, 5(7):1073-1076]

Cited: 20 times

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Magnetocardiography-guided management of an unusual case of isoimmune complete atrioventricular block complicated by ventricular tachycardia.

Bibhuti Das, Bettina F Cuneo, Mark Ovadia, Janette F Strasburger, Christopher Johnsrude, Ronald T Wakai,

A fetus who was diagnosed at 25 weeks of gestation with isoimmune AV block presented at 34 weeks with a precipitous fall in ventricular rate and periods of tachycardia. Magnetocardiography revealed the tachycardia to be ventricular. After delivery, nonsustained ventricular tachycardia continued. The baby then successfully paced, and at higher ... Read more >>

Fetal. Diagn. Ther. (Fetal diagnosis and therapy)
[2008, 24(3):282-285]

Cited: 1 time

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Fetal electrophysiology.

Janette F Strasburger,

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2008, 31(9):1087-1088]

Cited: 0 times

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Perinatal arrhythmias: diagnosis and management.

Janette F Strasburger, Bageshree Cheulkar, Heather J Wichman,

The final common pathway to death in all of us is an arrhythmia, yet we still know far too little about the contribution of conduction abnormalities and arrhythmias to the compromised states of the human fetus. At no other time in the human life cycle is the human being at ... Read more >>

Clin Perinatol (Clinics in perinatology)
[2007, 34(4):627-52, vii-viii]

Cited: 17 times

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