Full Text Journal Articles by
Author Jakob Schmitt

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DXA reference values of the humanoid sheep model in preclinical studies.

Christoph Biehl, Jakob Schmitt, Sabine Stoetzel, Deeksha Malhan, Fathi Hassan, Gero Knapp, Christian Heiss, Thaqif El Khassawna,

<h4>Background</h4>Merino land sheep are a popular pre-clinical large animal model in research on systemic skeletal diseases such as osteoporosis. Interpretation of studies is difficult because many reference parameters are missing or not established. This study aims to determine the reference parameters of the skeletal system (peak bone mass = PBM, ... Read more >>

PeerJ (PeerJ)
[2021, 9:e11183]

Cited: 0 times

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A New Clinically Relevant T-Score Standard to Interpret Bone Status in a Sheep Model.

Christian Heiss, Stefanie Kern, Deeksha Malhan, Wolfgang Böcker, Markus Engelhardt, Diaa Eldin S Daghma, Sabine Stoetzel, Jakob Schmitt, Matthias Ivo, Vivien Kauschke, Katrin S Lips, Kamen Tushtev, Kurosch Rezwan, Thaqif El Khassawna,

BACKGROUND Osteoporosis is diagnosed by bone loss using a radiological parameter called T-score. Preclinical studies use DXA to evaluate bone status were the T-score is referenced on bone mineral density (BMD) values of the same animals before treatment. Clinically, the reference BMD represents values of an independent group of healthy ... Read more >>

Med Sci Monit Basic Res (Medical science monitor basic research)
[2017, 23:326-335]

Cited: 5 times

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