Full Text Journal Articles by
Author Jacqueline King

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Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020.

Nicola S Lewis, Ashley C Banyard, Elliot Whittard, Talgat Karibayev, Thamer Al Kafagi, Ilya Chvala, Alex Byrne, Saduakassova Meruyert Akberovna, Jacqueline King, Timm Harder, Christian Grund, Steve Essen, Scott M Reid, Adam Brouwer, Nikolay G Zinyakov, Azimkhan Tegzhanov, Victor Irza, Anne Pohlmann, Martin Beer, Ron A M Fouchier, Sultanov Akhmetzhan Akievich, Ian H Brown,

Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected maintenance of H5N8, likely in galliform poultry since 2017/18 and both H5N5 and H5N1. ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):148-151]

Cited: 9 times

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Cattle connection: molecular epidemiology of BVDV outbreaks via rapid nanopore whole-genome sequencing of clinical samples.

Jacqueline King, Anne Pohlmann, Kamila Dziadek, Martin Beer, Kerstin Wernike,

<h4>Background</h4>As a global ruminant pathogen, bovine viral diarrhea virus (BVDV) is responsible for the disease Bovine Viral Diarrhea with a variety of clinical presentations and severe economic losses worldwide. Classified within the Pestivirus genus, the species Pestivirus A and B (syn. BVDV-1, BVDV-2) are genetically differentiated into 21 BVDV-1 and ... Read more >>

BMC Vet Res (BMC veterinary research)
[2021, 17(1):242]

Cited: 0 times

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An Examination of the Feasibility of Detecting Cocaine Use Using Smartwatches.

Emre Ertin, Nithin Sugavanam, August F Holtyn, Kenzie L Preston, Jeremiah W Bertz, Lisa A Marsch, Bethany McLeman, Dikla Shmueli-Blumberg, Julia Collins, Jacqueline S King, Jennifer McCormack, Udi E Ghitza,

As digital technology increasingly informs clinical trials, novel ways to collect study data in the natural field setting have the potential to enhance the richness of research data. Cocaine use in clinical trials is usually collected <i>via</i> self-report and/or urine drug screen results, both of which have limitations. This article ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2021, 12:674691]

Cited: 0 times

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Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1.

Jacob Schön, Angele Breithaupt, Dirk Höper, Jacqueline King, Anne Pohlmann, Rokshana Parvin, Klaus-Peter Behr, Bernd-Andreas Schwarz, Martin Beer, Jürgen Stech, Timm Harder, Christian Grund,

Repeated outbreaks due to H3N1 low pathogenicity avian influenza viruses (LPAIV) in Belgium were associated with unusually high mortality in chicken in 2019. Those events caused considerable economic losses and prompted restriction measures normally implemented for eradicating high pathogenicity avian influenza viruses (HPAIV). Initial pathology investigations and infection studies suggested ... Read more >>

PLoS Pathog (PLoS pathogens)
[2021, 17(4):e1009490]

Cited: 1 time

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Genetic and antigenic evolution of H1 swine influenza A viruses isolated in Belgium and the Netherlands from 2014 through 2019.

Sharon Chepkwony, Anna Parys, Elien Vandoorn, Wojciech Stadejek, Jiexiong Xie, Jacqueline King, Annika Graaf, Anne Pohlmann, Martin Beer, Timm Harder, Kristien Van Reeth,

Surveillance of swine influenza A viruses (swIAV) allows timely detection and identification of new variants with potential zoonotic risks. In this study, we aimed to identify swIAV subtypes that circulated in pigs in Belgium and the Netherlands between 2014 and 2019, and characterize their genetic and antigenic evolution. We subtyped ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):11276]

Cited: 0 times

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Human Infection with Eurasian Avian-Like Swine Influenza A(H1N1) Virus, the Netherlands, September 2019.

Anna Parys, Elien Vandoorn, Jacqueline King, Annika Graaf, Anne Pohlmann, Martin Beer, Timm Harder, Kristien Van Reeth,

We report a zoonotic infection of a pig farmer in the Netherlands with a Eurasian avian-like swine influenza A(H1N1) virus that was also detected in the farmed pigs. Both viruses were antigenically and genetically characterized. Continued surveillance of swine influenza A viruses is needed for risk assessment in humans and ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2021, 27(3):939-943]

Cited: 2 times

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SARS-CoV-2 spike D614G change enhances replication and transmission.

Bin Zhou, Tran Thi Nhu Thao, Donata Hoffmann, Adriano Taddeo, Nadine Ebert, Fabien Labroussaa, Anne Pohlmann, Jacqueline King, Silvio Steiner, Jenna N Kelly, Jasmine Portmann, Nico Joel Halwe, Lorenz Ulrich, Bettina Salome Trüeb, Xiaoyu Fan, Bernd Hoffmann, Li Wang, Lisa Thomann, Xudong Lin, Hanspeter Stalder, Berta Pozzi, Simone de Brot, Nannan Jiang, Dan Cui, Jaber Hossain, Malania M Wilson, Matthew W Keller, Thomas J Stark, John R Barnes, Ronald Dijkman, Joerg Jores, Charaf Benarafa, David E Wentworth, Volker Thiel, Martin Beer,

During the evolution of SARS-CoV-2 in humans, a D614G substitution in the spike glycoprotein (S) has emerged; virus containing this substitution has become the predominant circulating variant in the COVID-19 pandemic<sup>1</sup>. However, whether the increasing prevalence of this variant reflects a fitness advantage that improves replication and/or transmission in humans ... Read more >>

Nature (Nature)
[2021, 592(7852):122-127]

Cited: 67 times

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Establishment of a Challenge Model for Sheeppox Virus Infection.

Janika Wolff, Sahar Abd El Rahman, Jacqueline King, Mohamed El-Beskawy, Anne Pohlmann, Martin Beer, Bernd Hoffmann,

Sheeppox virus (SPPV) together with goatpox virus and lumpy skin disease virus form the genus <i>Capripoxvirus</i> of the <i>Poxviridae</i> family. Due to their great economic importance and major impact on livelihood of small-scale farmers, OIE guidelines classify capripox viruses as notifiable diseases. In the present study, we examined pathogenesis of ... Read more >>

Microorganisms (Microorganisms)
[2020, 8(12):]

Cited: 3 times

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SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

Bin Zhou, Tran Thi Nhu Thao, Donata Hoffmann, Adriano Taddeo, Nadine Ebert, Fabien Labroussaa, Anne Pohlmann, Jacqueline King, Jasmine Portmann, Nico Joel Halwe, Lorenz Ulrich, Bettina Salome Trüeb, Jenna Kelly, Xiaoyu Fan, Bernd Hoffmann, Silvio Steiner, Li Wang, Lisa Thomann, Xudong Lin, Hanspeter Stalder, Berta Pozzi, Simone de Brot, Nannan Jiang, Dan Cui, Jaber Hossain, Malania Wilson, Matthew Keller, Thomas Stark, John Barnes, Ronald Dijkman, Joerg Jores, Charaf Benarafa, David Wentworth, Volker Thiel, Martin Beer,

During the evolution of SARS-CoV-2 in humans a D614G substitution in the spike (S) protein emerged and became the predominant circulating variant (S-614G) of the COVID-19 pandemic 1 . However, whether the increasing prevalence of the S-614G variant represents a fitness advantage that improves replication and/or transmission in humans or ... Read more >>

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Experimental Infection and Genetic Characterization of Two Different Capripox Virus Isolates in Small Ruminants.

Janika Wolff, Jacqueline King, Tom Moritz, Anne Pohlmann, Donata Hoffmann, Martin Beer, Bernd Hoffmann,

Capripox viruses, with their members "lumpy skin disease virus (LSDV)", "goatpox virus (GTPV)" and "sheeppox virus (SPPV)", are described as the most serious pox diseases of production animals. A GTPV isolate and a SPPV isolate were sequenced in a combined approach using nanopore MinION sequencing to obtain long reads and ... Read more >>

Viruses (Viruses)
[2020, 12(10):]

Cited: 4 times

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The genetics of highly pathogenic avian influenza viruses of subtype H5 in Germany, 2006-2020.

Jacqueline King, Timm Harder, Franz J Conraths, Martin Beer, Anne Pohlmann,

The H5 A/Goose/Guangdong/1/1996 (gs/GD) lineage emerged in China in 1996. Rooted in the respective gs/GD lineage, the hemagglutinin (HA) gene of highly pathogenic avian influenza viruses (HPAIV) has genetically diversified into a plethora of clades and subclades and evolved into an assortment of sub- and genotypes. Some caused substantial losses ... Read more >>

Transbound Emerg Dis (Transboundary and emerging diseases)
[2021, 68(3):1136-1150]

Cited: 1 time

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Rapid multiplex MinION nanopore sequencing workflow for Influenza A viruses.

Jacqueline King, Timm Harder, Martin Beer, Anne Pohlmann,

<h4>Background</h4>Due to the frequent reassortment and zoonotic potential of influenza A viruses, rapid gain of sequence information is crucial. Alongside established next-generation sequencing protocols, the MinION sequencing device (Oxford Nanopore Technologies) has become a serious competitor for routine whole-genome sequencing. Here, we established a novel, rapid and high-throughput MinION multiplexing ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2020, 20(1):648]

Cited: 3 times

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The Cost of Pre-Analytical Errors in INR Testing at a Tertiary-Care Hospital Laboratory: Potential for Significant Cost Savings.

Sumedha Kulkarni, Dina Piraino, Rachel Strauss, Eva Proctor, Suzanne Waldman, Jacqueline King, Rita Selby,

<h4>Background</h4>Preanalytical errors account for most laboratory errors. Although the frequencies of preanalytical errors are well characterized in the literature, little is known regarding the costs of these errors to the laboratory.<h4>Objective</h4>To analyze costs associated with preanalytical errors associated with the international normalized ratio (INR) test.<h4>Methods</h4>We performed a retrospective analysis of ... Read more >>

Lab Med (Laboratory medicine)
[2020, 51(3):320-324]

Cited: 0 times

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Novel HPAIV H5N8 Reassortant (Clade 2.3.4.4b) Detected in Germany.

Jacqueline King, Christoph Schulze, Andreas Engelhardt, Andreas Hlinak, Sara-Lisa Lennermann, Kerstin Rigbers, Jasmin Skuballa, Christoph Staubach, Thomas C Mettenleiter, Timm Harder, Martin Beer, Anne Pohlmann,

A novel H5N8 highly pathogenic avian influenza virus (HPAIV) was detected in a greater white-fronted goose in January 2020 in Brandenburg, Germany, and, in February 2020, in domestic chickens belonging to a smallholding in Baden-Wuerttemberg, Germany. Full-genome sequencing was conducted on the MinION platform, enabling further phylogenetic analyses. The virus ... Read more >>

Viruses (Viruses)
[2020, 12(3):]

Cited: 14 times

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Novel Reassortant Highly Pathogenic Avian Influenza A(H5N2) Virus in Broiler Chickens, Egypt.

Kareem E Hassan, Jacqueline King, Magdy El-Kady, Manal Afifi, Hassanein H Abozeid, Anne Pohlmann, Martin Beer, Timm Harder,

We detected a novel reassortant highly pathogenic avian influenza A(H5N2) virus in 3 poultry farms in Egypt. The virus carried genome segments of a pigeon H9N2 influenza virus detected in 2014, a nucleoprotein segment of contemporary chicken H9N2 viruses from Egypt, and hemagglutinin derived from the 2.3.4.4b H5N8 virus clade. ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2020, 26(1):129-133]

Cited: 4 times

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Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.

Anne Pohlmann, Donata Hoffmann, Christian Grund, Susanne Koethe, Daniela Hüssy, Simone M Meier, Jacqueline King, Jan Schinköthe, Reiner Ulrich, Timm Harder, Martin Beer,

We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment. ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2019, 25(10):1973-1976]

Cited: 5 times

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Validation of the TAPS-1: A Four-Item Screening Tool to Identify Unhealthy Substance Use in Primary Care.

Jan Gryczynski, Jennifer McNeely, Li-Tzy Wu, Geetha A Subramaniam, Dace S Svikis, Lauretta A Cathers, Gaurav Sharma, Jacqueline King, Eve Jelstrom, Courtney D Nordeck, Anjalee Sharma, Shannon G Mitchell, Kevin E O'Grady, Robert P Schwartz,

<h4>Background</h4>The Tobacco, Alcohol, Prescription Medication, and Other Substance use (TAPS) tool is a combined two-part screening and brief assessment developed for adult primary care patients. The tool's first-stage screening component (TAPS-1) consists of four items asking about past 12-month use for four substance categories, with response options of never, less ... Read more >>

J Gen Intern Med (Journal of general internal medicine)
[2017, 32(9):990-996]

Cited: 8 times

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A randomized placebo-controlled trial of N-acetylcysteine for cannabis use disorder in adults.

Kevin M Gray, Susan C Sonne, Erin A McClure, Udi E Ghitza, Abigail G Matthews, Aimee L McRae-Clark, Kathleen M Carroll, Jennifer S Potter, Katharina Wiest, Larissa J Mooney, Albert Hasson, Sharon L Walsh, Michelle R Lofwall, Shanna Babalonis, Robert W Lindblad, Steven Sparenborg, Aimee Wahle, Jacqueline S King, Nathaniel L Baker, Rachel L Tomko, Louise F Haynes, Ryan G Vandrey, Frances R Levin,

<h4>Background</h4>Cannabis use disorder (CUD) is a prevalent and impairing condition, and established psychosocial treatments convey limited efficacy. In light of recent findings supporting the efficacy of N-acetylcysteine (NAC) for CUD in adolescents, the objective of this trial was to evaluate its efficacy in adults.<h4>Methods</h4>In a 12-week double-blind randomized placebo-controlled trial, ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2017, 177:249-257]

Cited: 40 times

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Comparing adult cannabis treatment-seekers enrolled in a clinical trial with national samples of cannabis users in the United States.

Erin A McClure, Jacqueline S King, Aimee Wahle, Abigail G Matthews, Susan C Sonne, Michelle R Lofwall, Aimee L McRae-Clark, Udi E Ghitza, Melissa Martinez, Kasie Cloud, Harvir S Virk, Kevin M Gray,

<h4>Background</h4>Cannabis use rates are increasing among adults in the United States (US) while the perception of harm is declining. This may result in an increased prevalence of cannabis use disorder and the need for more clinical trials to evaluate efficacious treatment strategies. Clinical trials are the gold standard for evaluating ... Read more >>

Drug Alcohol Depend (Drug and alcohol dependence)
[2017, 176:14-20]

Cited: 7 times

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Baseline Factors Associated With 6-Month Visual Acuity and Retinal Thickness Outcomes in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion or Hemiretinal Vein Occlusion: SCORE2 Study Report 4.

Ingrid U Scott, Paul C VanVeldhuisen, Michael S Ip, Barbara A Blodi, Neal L Oden, Jacqueline King, Andrew N Antoszyk, Mark A Peters, Michael Tolentino, ,

<h4>Importance</h4>Macular edema (ME) is the leading cause of decreased visual acuity (VA) associated with retinal vein occlusion (RVO). Identifying factors associated with better outcomes in RVO eyes treated with anti-vascular endothelial growth factor (VEGF) therapy may provide information useful in counseling patients.<h4>Objective</h4>To investigate baseline characteristics associated with 6-month VA and ... Read more >>

JAMA Ophthalmol (JAMA ophthalmology)
[2017, 135(6):639-649]

Cited: 9 times

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Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion: The SCORE2 Randomized Clinical Trial.

Ingrid U Scott, Paul C VanVeldhuisen, Michael S Ip, Barbara A Blodi, Neal L Oden, Carl C Awh, Derek Y Kunimoto, Dennis M Marcus, John J Wroblewski, Jacqueline King, ,

<h4>Importance</h4>Studies have established the efficacy and safety of aflibercept for the treatment of macular edema due to central retinal vein occlusion. Bevacizumab is used off-label to treat this condition despite the absence of supporting data.<h4>Objective</h4>To investigate whether bevacizumab is noninferior to aflibercept for the treatment of macular edema secondary to ... Read more >>

JAMA (JAMA)
[2017, 317(20):2072-2087]

Cited: 58 times

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Performance of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) Tool for Substance Use Screening in Primary Care Patients.

Jennifer McNeely, Li-Tzy Wu, Geetha Subramaniam, Gaurav Sharma, Lauretta A Cathers, Dace Svikis, Luke Sleiter, Linnea Russell, Courtney Nordeck, Anjalee Sharma, Kevin E O'Grady, Leah B Bouk, Carol Cushing, Jacqueline King, Aimee Wahle, Robert P Schwartz,

<h4>Background</h4>Substance use, a leading cause of illness and death, is underidentified in medical practice.<h4>Objective</h4>The Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS) tool was developed to address the need for a brief screening and assessment instrument that includes all commonly used substances and fits into clinical workflows. The goal ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2016, 165(10):690-699]

Cited: 47 times

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The European System for Cardia Operative Risk Evaluation (Euroscore) II as a Predictor of Prolonged Extubation in Patients Undergoing Valvular Surgery

Chunrong Lin, Jacqueline King, Jamie Rubin, Samuel Evans,

<h4>Introduction</h4> The EuroSCORE II was updated from the EuroSCORE I and validated this year as a predictor for in-hospital mortality after cardiac surgery. The EuroSCORE I was previously shown in multiple studies to be a good predictor of delayed extubation in patients undergoing coronary artery bypass graft (CABG) surgery. In ... Read more >>

Hawaii J Med Public Health (Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health)
[2013, 72(9 Suppl 4):45-45]

Cited: 0 times

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Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study.

M Cristina Kenney, Dieter Hertzog, Garrick Chak, Shari R Atilano, Nikan Khatibi, Kyaw Soe, Andrew Nobe, Elizabeth Yang, Marilyn Chwa, Feilin Zhu, Masood Memarzadeh, Jacqueline King, Jonathan Langberg, Kent Small, Anthony B Nesburn, David S Boyer, Nitin Udar,

<h4>Background</h4>Age-related macular degeneration (AMD) is the leading cause of vision loss in elderly, Caucasian populations. There is strong evidence that mitochondrial dysfunction and oxidative stress play a role in the cell death found in AMD retinas. The purpose of this study was to examine the association of the Caucasian mitochondrial ... Read more >>

BMC Med Genet (BMC medical genetics)
[2013, 14:4]

Cited: 23 times

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Insulin pump therapy: guidelines for successful outcomes.

Gary Scheiner, Robert J Sobel, Daphne E Smith, Anthony J Pick, Davida Kruger, Jacqueline King, Karen Green,

<h4>Purpose</h4>Current forms of insulin delivery used in the treatment of diabetes mellitus (diabetes) include syringes, pens, and insulin pumps. Technical advantages of insulin pump therapy, or continuous subcutaneous insulin delivery (CSII), include precise and flexible insulin dosing. In the context of intensive diabetes management, insulin pumps can facilitate improved long-term ... Read more >>

Diabetes Educ (The Diabetes educator)
[2009, 35 Suppl 2:29S-41S; quiz 28S, 42S-43S]

Cited: 27 times

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