Full Text Journal Articles by
Author J Gallagher

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Have Legislative Interventions Impacted the Incidence of Needlestick Injuries?

G O'Sullivan, J Gallagher,

Introduction The aim of this study was to examine the impact the EU Directive for the Prevention of Sharps injuries had on the incidence of needlestick injuries (NSI) in Ireland. Methods A five-year retrospective study prior to, and after the introduction of these regulations, was conducted. Secondary data from the ... Read more >>

Ir Med J (Irish medical journal)
[2020, 112(10):1023]

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Rhetorical Appeals and Tactics in New York Times Comments About Vaccines: Qualitative Analysis.

John Gallagher, Heidi Y Lawrence,

<b>Background: </b>Improving persuasion in response to vaccine skepticism is a long-standing problem. Elective nonvaccination emerging from skepticism about vaccine safety and efficacy jeopardizes herd immunity, exposing those who are most vulnerable to the risk of serious diseases.<br><br><b>Objective: </b>This article analyzes vaccine sentiments in the New York Times as a way ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2020, 22(12):e19504]

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Oxidative Stress Responses and Nutrient Starvation in MCHM Treated Saccharomyces cerevisiae.

Michael C Ayers, Zachary N Sherman, Jennifer E G Gallagher,

In 2014, the coal cleaning chemical 4-methylcyclohexane methanol (MCHM) spilled into the water supply for 300,000 West Virginians. Initial toxicology tests showed relatively mild results, but the underlying effects on cellular biology were underexplored. Treated wildtype yeast cells grew poorly, but there was only a small decrease in cell viability. ... Read more >>

G3 (Bethesda) (G3 (Bethesda, Md.))
[2020, 10(12):4665-4678]

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A follow-up study of patients with natural rubber latex allergy.

Eilis Nic Dhonncha, Siobhán McCarthy, Lisa Roche, John Gallagher, John F Bourke,

Contact Dermatitis (Contact dermatitis)
[2020, :]

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Dental Caries Thresholds among Adolescents in England, Wales and Northern Ireland, 2013 at 12, and 15 years: Implications for Epidemiology and Clinical Care

Xiaozhe Wang, Eduardo Bernabe, Nigel Pitts, Shuguo Zheng, Jennifer Gallagher,

Abstract Background Dental caries is the most prevalent condition globally. Despite improvements over the past few decades, there remains a significant disease burden in childhood. Epidemiological surveys provide insight to disease patterns and trends, have traditionally focused on obvious decay which are inconsistent with contemporary clinical criteria. This study examined ... Read more >>

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A systematic review of contamination (aerosol, splatter and droplet generation) associated with oral surgery and its relevance to COVID-19.

Jennifer E Gallagher, Sukriti K C, Ilona G Johnson, Waraf Al-Yaseen, Rhiannon Jones, Scott McGregor, Mark Robertson, Rebecca Harris, Nicola Innes, William G Wade,

Introduction:The current COVID-19 pandemic caused by the SARS-CoV-2 virus has impacted the delivery of dental care globally and has led to re-evaluation of infection control standards. However, lack of clarity around what is known and unknown regarding droplet and aerosol generation in dentistry (including oral surgery and extractions), and their ... Read more >>

BDJ Open (BDJ open)
[2020, 6:25]

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A Clinical Review and Critical Evaluation of Imipenem-Relebactam: Evidence to Date.

Toni A Campanella, Jason C Gallagher,

Imipenem-relebactam (I-R) is a novel beta-lactam/beta-lactamase inhibitor combination given with cilastatin. It is indicated for the treatment of complicated urinary tract infections, complicated intra-abdominal infections, and hospital-acquired or ventilator-associated bacterial pneumonia. A literature search was completed to evaluate the evidence to date of I-R. I-R has in vitro activity against ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2020, 13:4297-4308]

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Dental Public Health Education in Europe: a survey of European Dental Schools to determine current practice and inform a core undergraduate programme.

N Rizvi, A Livny, I Chestnutt, J Virtanen, J E Gallagher,

<b>Objective: </b>Describe current Dental Public Health [DPH] curricula content and delivery across European dental schools and ascertain views on a core undergraduate curriculum for dental students.<br><br><b>Research design: </b>Survey of European dental schools, informed by professional and academic literature and European Association for Dental Public Health [EADPH] Special Interest Working Group ... Read more >>

Community Dent Health (Community dental health)
[2020, 37(4):275-280]

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Author Correction: Modeling COVID-19 scenarios for the United States.

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A Correction to this paper has been published: https://doi.org/10.1038/s41591-020-01181-w. ... Read more >>

Nat Med (Nature medicine)
[2020, :]

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Corrigendum to "Longevity and sustainability of tropical and subtropical restored seagrass beds among Atlantic, Pacific, and Indian Oceans" [Mar. Pollut. Bull. Volume 160, November 2020, 111544].

Anitra Thorhaug, Charles Belaire, Jennifer J Verduin, Arthur Schwarz, Wawan Kiswara, Anchana Prathep, John Barry Gallagher, Xiao Ping Huang, Graeme Berlyn, Tzuen-Kiat Yap, Susan Dorward,

Mar Pollut Bull (Marine pollution bulletin)
[2020, :111802]

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COVID-19 Pandemic: The Role of EMS Physicians in a Community Response Effort.

José G Cabañas, Jefferson G Williams, John M Gallagher, Jane H Brice,

The COVID-19 pandemic is a worldwide historical event that will continue to affect nearly every aspect of ordinary life, including affecting our economic, political, and healthcare eco-systems. An effective pandemic response demands a coordinated and integrated response across community healthcare stakeholders, including Public Health and Emergency Management Officials. EMS systems ... Read more >>

Prehosp Emerg Care (Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors)
[2020, :1-8]

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Frequency, diagnosis, pathogenesis and management of osteoporosis in alkaptonuria: data analysis from the UK National Alkaptonuria Centre.

L R Ranganath, M Khedr, S Vinjamuri, J A Gallagher,

Osteoporosis and fractures are common features of alkaptonuria. INTRODUCTION:A large cohort of alkaptonuria (AKU) patients was studied to better recognise and characterise osteoporosis and fractures in AKU. METHODS:Assessments including questionnaire analysis, DEXA and CT densitometry at the neck of femur (FN), total hip (TH) and lumbar spine (LS) were performed ... Read more >>

Osteoporos Int (Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA)
[2020, :]

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Distinct Genomic Alterations in Prostate Tumors Derived from African American Men.

Wennuan Liu, S Lilly Zheng, Rong Na, Lin Wei, Jishan Sun, Johnie Gallagher, Jun Wei, W Kyle Resurreccion, Sarah Ernst, Karen S Sfanos, William B Isaacs, Jianfeng Xu,

We aim to understand, from acquired genetic alterations in tumors, why African American (AA) men are more likely to develop aggressive prostate cancer. By analyzing somatic mutations in 39 genes using deeper next-generation sequencing with an average depth of 2,522 reads for tumor DNA and genome-wide DNA copy-number alterations (CNA) ... Read more >>

Mol Cancer Res (Molecular cancer research : MCR)
[2020, 18(12):1815-1824]

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Modeling COVID-19 scenarios for the United States.

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We use COVID-19 case and mortality data from 1 February 2020 to 21 September 2020 and a deterministic SEIR (susceptible, exposed, infectious and recovered) compartmental framework to model possible trajectories of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the effects of non-pharmaceutical interventions in the United States at ... Read more >>

Nat Med (Nature medicine)
[2020, :]

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Randomized pilot trial of ipratropium versus placebo in children with critical asthma.

Kaitlyn Murphy, Nabihah Mahmood, Daniel Craven, John Gallagher, Kristie Ross, Richard Speicher, Alexandre T Rotta, Steven L Shein,

OBJECTIVE:To test the effects of inhaled ipratropium on clinical outcomes of critical asthma in the first randomized trial of this adjunctive therapy in critically ill children. DESIGN:Pilot, placebo-controlled, double-blinded, and randomized-controlled trial PATIENTS: Thirty children (15 per group) with critical asthma receiving high-intensity albuterol per a standardized pathway utilizing objective ... Read more >>

Pediatr Pulmonol (Pediatric pulmonology)
[2020, 55(12):3287-3292]

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Changing to remote management of a community heart failure population during COVID-19 - Clinician and patient perspectives'.

Brian Kerr, Rebabonye B Pharithi, Matthew Barrett, Carmel Halley, Joe Gallagher, Mark Ledwidge, Kenneth McDonald,

Background:The COVID pandemic has challenged the traditional methods used in care of patients with heart failure (HF). Remote management of HF patients has been recommended in order to maintain routine standards of care, but satisfaction with this platform of care is unknown. We set out to address the physician and ... Read more >>

Int J Cardiol Heart Vasc (International journal of cardiology. Heart & vasculature)
[2020, 31:100665]

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Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients.

Annie M Racine, Douglas Tommet, Madeline L D'Aquila, Tamara G Fong, Yun Gou, Patricia A Tabloski, Eran D Metzger, Tammy T Hshieh, Eva M Schmitt, Sarinnapha M Vasunilashorn, Lisa Kunze, Kamen Vlassakov, Ayesha Abdeen, Jeffrey Lange, Brandon Earp, Bradford C Dickerson, Edward R Marcantonio, Jon Steingrimsson, Thomas G Travison, Sharon K Inouye, Richard N Jones, ,

BACKGROUND:Our objective was to assess the performance of machine learning methods to predict post-operative delirium using a prospective clinical cohort. METHODS:We analyzed data from an observational cohort study of 560 older adults (≥ 70 years) without dementia undergoing major elective non-cardiac surgery. Post-operative delirium was determined by the Confusion Assessment Method supplemented ... Read more >>

J Gen Intern Med (Journal of general internal medicine)
[2020, :]

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Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces.

Juliette H Hughes, Craig M Keenan, Hazel Sutherland, Henry R Edwards, Peter J M Wilson, Lakshminarayan R Ranganath, Jonathan C Jarvis, George Bou-Gharios, James A Gallagher,

Alkaptonuria (AKU) is characterised by increased circulating homogentisic acid and deposition of ochronotic pigment in collagen-rich connective tissues (ochronosis), stiffening the tissue. This process over many years leads to a painful and severe osteoarthropathy, particularly affecting the cartilage of the spine and large weight bearing joints. Evidence in human AKU ... Read more >>

Calcif Tissue Int (Calcified tissue international)
[2020, :]

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Coastal and estuarine blue carbon stocks in the greater Southeast Asia region: Seagrasses and mangroves per nation and sum of total.

A Thorhaug, John Barry Gallagher, W Kiswara, Anchana Prathep, Xiaoping Huang, Tzuen-Kiat Yap, Sue Dorward, Graeme Berlyn,

Climate Change solutions include CO2 extraction from atmosphere and water with burial by living habitats in sediment/soil. Nowhere on the planet are blue carbon plants which carry out massive carbon extraction and permanent burial more intensely concentrated than in SE Asia. For the first time we make a national and ... Read more >>

Mar Pollut Bull (Marine pollution bulletin)
[2020, 160:111168]

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Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer.

Stephan B Dreyer, Rosie Upstill-Goddard, Viola Paulus-Hock, Clara Paris, Eirini-Maria Lampraki, Eloise Dray, Bryan Serrels, Giuseppina Caligiuri, Selma Rebus, Dennis Plenker, Zachary Galluzzo, Holly Brunton, Richard Cunningham, Mathias Tesson, Craig Nourse, Ulla-Maja Bailey, Marc Jones, Kim Moran-Jones, Derek W Wright, Fraser Duthie, Karin Oien, Lisa Evers, Colin J McKay, Grant A McGregor, Aditi Gulati, Rachel Brough, Ilirjana Bajrami, Stephan Pettitt, Michele L Dziubinski, Juliana Candido, Frances Balkwill, Simon T Barry, Robert Grützmann, Lola Rahib, , , Amber Johns, Marina Pajic, Fieke E M Froeling, Phillip Beer, Elizabeth A Musgrove, Gloria M Petersen, Alan Ashworth, Margaret C Frame, Howard C Crawford, Diane M Simeone, Chris Lord, Debabrata Mukhopadhyay, Christian Pilarsky, David A Tuveson, Susanna L Cooke, Nigel B Jamieson, Jennifer P Morton, Owen J Sansom, Peter J Bailey, Andrew V Biankin, David K Chang,

BACKGROUND & AIMS:Continuing recalcitrance to therapy cements pancreatic cancer (PC) as the most lethal malignancy, which is set to become the second leading cause of cancer death in our society. The study aim was to investigate the association between DNA damage response (DDR), replication stress, and novel therapeutic response in ... Read more >>

Gastroenterology (Gastroenterology)
[2020, :]

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Longevity and sustainability of tropical and subtropical restored seagrass beds among Atlantic, Pacific, and Indian Oceans.

Anitra Thorhaug, Charles Belaire, Jennifer J Verduin, Arthur Schwarz, Wawan Kiswara, Anchana Prathep, John Barry Gallagher, Xiao Ping Huang, Graeme Berlyn, Tzuen-Kiat Yap, Susan Dorward,

Seagrass longevity up to 47 years in well-restored, well-sited seagrass restorations are demonstrated from 253 trials at 83 regional sites in tropical and subtropical portions of three oceans (Atlantic, Pacific, Indian Oceans). These trials include over 3.04 million planted units into 306.3 ha. Approximately 12% of the total global tropical restored seagrass ... Read more >>

Mar Pollut Bull (Marine pollution bulletin)
[2020, 160:111544]

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Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.

, Peter Horby, Marion Mafham, Louise Linsell, Jennifer L Bell, Natalie Staplin, Jonathan R Emberson, Martin Wiselka, Andrew Ustianowski, Einas Elmahi, Benjamin Prudon, Tony Whitehouse, Timothy Felton, John Williams, Jakki Faccenda, Jonathan Underwood, J Kenneth Baillie, Lucy C Chappell, Saul N Faust, Thomas Jaki, Katie Jeffery, Wei Shen Lim, Alan Montgomery, Kathryn Rowan, Joel Tarning, James A Watson, Nicholas J White, Edmund Juszczak, Richard Haynes, Martin J Landray,

<b>Background:</b>Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from uncontrolled studies and small, randomized trials.<br><br><b>Methods:</b>In this randomized, controlled, open-label platform trial comparing a range of possible treatments with usual care in patients hospitalized with Covid-19, we ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 383(21):2030-2040]

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Incidence of venous thromboembolism in coronavirus disease 2019: An experience from a single large academic center.

Parth Rali, Oisin O'Corragain, Lawrence Oresanya, Daohai Yu, Omar Sheriff, Robert Weiss, Catherine Myers, Parag Desai, Nadia Ali, Anthony Stack, Michael Bromberg, Andrea L Lubitz, Joseph Panaro, Riyaz Bashir, Vladimir Lakhter, Roberto Caricchio, Rohit Gupta, Chandra Dass, Kumaran Maruti, Xiaoning Lu, A Koneti Rao, Gary Cohen, Gerard J Criner, Eric T Choi, ,

BACKGROUND:Infection with the novel severe acute respiratory syndrome coronavirus 2 has been associated with a hypercoagulable state. Emerging data from China and Europe have consistently shown an increased incidence of venous thromboembolism (VTE). We aimed to identify the VTE incidence and early predictors of VTE at our high-volume tertiary care ... Read more >>

J Vasc Surg Venous Lymphat Disord (Journal of vascular surgery. Venous and lymphatic disorders)
[2020, :]

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Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis.

Aaron I Gardner, Iram J Haq, A John Simpson, Katrin A Becker, John Gallagher, Vinciane Saint-Criq, Bernard Verdon, Emily Mavin, Alexandra Trigg, Michael A Gray, Albert Koulman, Melissa J McDonnell, Andrew J Fisher, Elizabeth L Kramer, John P Clancy, Christopher Ward, Edward H Schuchman, Erich Gulbins, Malcolm Brodlie,

Rationale: In cystic fibrosis the major cause of morbidity and mortality is lung disease characterized by inflammation and infection. The influence of sphingolipid metabolism is poorly understood with a lack of studies using human airway model systems.Objectives: To investigate sphingolipid metabolism in cystic fibrosis and the effects of treatment with ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2020, 202(8):1133-1145]

Cited: 1 time

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Is our bTB policy one of the worst attempts to control a major notifiable disease ever seen?

John Gallagher, Roger W Blowey, Roger Sainsbury, Linda Farrant, John Head, Neil M Howie, Richard H Thomas,

A group of experienced vets argue that the lack of control of endemically TB-infected communities of badgers has resulted in a bovine TB dilemma that is worse now than it was 50 years ago. ... Read more >>

Vet Rec (The Veterinary record)
[2020, 187(7):281]

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