Full Text Journal Articles by
Author Ivo Buschmann

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Risk Factor Management in Non-Metropolitan Patients with Coronary and Peripheral Artery Disease - A Protocol of a Prospective, Multi-Center, Quality Improvement Strategy.

Claudia Zemmrich, Peter Bramlage, Philipp Hillmeister, Mesud Sacirovic, Ivo Buschmann,

<h4>Introduction</h4>Coronary artery disease (CAD) and peripheral arterial disease (PAD) account for significant morbidity and mortality in Germany and are more prevalent in rural, non-metropolitan areas. The goal of this study is to screen patients for their current atherosclerotic status, initiate treatment according to the latest scientific findings using a standardised ... Read more >>

Vasc Health Risk Manag (Vascular health and risk management)
[2021, 17:267-272]

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Guidelines adherence in the prevention and management of chronic kidney disease in patients with diabetes mellitus on the background of recent European recommendations - a registry-based analysis.

Peter Bramlage, Stefanie Lanzinger, Sascha R Tittel, Eva Hess, Simon Fahrner, Christoph H J Heyer, Mathias Friebe, Ivo Buschmann, Thomas Danne, Jochen Seufert, Reinhard W Holl,

<h4>Background</h4>Recent European Society of Cardiology (ESC)/European Association for the Study of Diabetes (EASD) guidelines provide recommendations for detecting and treating chronic kidney disease (CKD) in diabetic patients. We compared clinical practice with guidelines to determine areas for improvement.<h4>Methods</h4>German database analysis of 675,628 patients with type 1 or type 2 diabetes, ... Read more >>

BMC Nephrol (BMC nephrology)
[2021, 22(1):184]

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Post-exercise pulsatility index indicates treatment effects in peripheral arterial occlusive disease (PAOD).

Andrej Udelnow, Maria Hawemann, Ivo Buschmann, Frank Meyer, Zuhir Halloul,

<h4>Background</h4>Hypothesis: Post-exercise measurements better discriminate PAOD-patients from healthy persons and they more sensitively detect hemodynamic improvements after treatment procedures than resting measurements.<h4>Methods</h4>A total of 19 healthy volunteers and 23 consecutive PAOD-patients underwent measurements of peak systolic velocity (PSV), end-diastolic velocity (EDV), minimal diastolic velocity (MDV), time-averaged maximum velocities (TAMAX), resistance ... Read more >>

Wien Klin Wochenschr (Wiener klinische Wochenschrift)
[2021, :]

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Impact of chemotherapeutic effects on the pathophysiology of the arterial wall - insights from peripheral arterial disease.

Christoph Lange, Njeri Ngare, Philipp Hillmeister, Peter Bramlage, Ralf Langhoff, Ivo Buschmann,

Systemic antineoplastic treatment agents represent one of the fastest developing medical fields. Oncological treatment is becoming increasingly individualized and new targets with corresponding agents, are constantly being developed. In tandem with this progress, new combinations and algorithms have evolved and patient's outcome have improved. Expanding tumors rely on a growing ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2021, 50(4):265-269]

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Type 2 diabetes in older patients: an analysis of the DPV and DIVE databases.

Gesine van Mark, Sascha R Tittel, Stefan Sziegoleit, Franz Josef Putz, Mesut Durmaz, Michaela Bortscheller, Ivo Buschmann, Jochen Seufert, Reinhard W Holl, Peter Bramlage,

<h4>Background</h4>The clinical profile differs between old and young patients with type 2 diabetes mellitus (T2DM). We explored, based on a large real-world database, patient and disease characteristics and actual treatment patterns by age.<h4>Methods</h4>The analysis was based on the DIVE and DPV registries of patients with T2DM. Patients were analyzed by ... Read more >>

Ther Adv Endocrinol Metab (Therapeutic advances in endocrinology and metabolism)
[2020, 11:2042018820958296]

Cited: 1 time

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Renal function deterioration in adult patients with type-2 diabetes.

Peter Bramlage, Stefanie Lanzinger, Eva Hess, Simon Fahrner, Christoph H J Heyer, Mathias Friebe, Ivo Buschmann, Thomas Danne, Reinhard W Holl, Jochen Seufert,

<h4>Background</h4>To explore, in a large group of patients with type-2 diabetes (T2DM), renal function decline in terms of the slope of the estimated glomerular filtration rate (eGFR) over time, and to find out how classical risk factors, such as the presence of hypertension, dyslipidemia and microalbuminuria, affect the renal function.<h4>Methods</h4>The ... Read more >>

BMC Nephrol (BMC nephrology)
[2020, 21(1):312]

Cited: 2 times

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Exercise and cardiovascular diseases.

Philipp Hillmeister, Marijana Tadic, Njeri Ngare, Nikolaos Pagonas, Ivo Buschmann,

Acta Physiol (Oxf) (Acta physiologica (Oxford, England))
[2020, 229(2):e13476]

Cited: 1 time

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Individual shear rate therapy (ISRT)-further development of external counterpulsation for decreasing blood pressure in patients with symptomatic coronary artery disease (CAD).

Frauke Picard, Petroula Panagiotidou, Anamaria Wolf-Pütz, Ivo Buschmann, Eva Buschmann, Maximilian Steffen, Hanno Peters, Rolf Michael Klein,

Individual shear rate therapy (ISRT) evolved from external counterpulsation with individual treatment pressures based on Doppler ultrasound measurements. In this study, we assessed the effect of ISRT on blood pressure (BP) in patients with coronary artery disease (CAD). Eighty-four patients with symptomatic CAD were included in the study. Forty-one patients ... Read more >>

Hypertens Res (Hypertension research : official journal of the Japanese Society of Hypertension)
[2020, 43(3):186-196]

Cited: 1 time

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Loop Diuretics in Acute Kidney Injury Prevention, Therapy, and Risk Stratification.

Daniel Patschan, Susann Patschan, Ivo Buschmann, Oliver Ritter,

<h4>Background</h4>Loop diuretics (LD) are widely used in emergency and intensive care medicine.<h4>Summary</h4>The substances increase the clearance of electrolytes and water; thus, they allow us to control hypervolemia and to prevent patients from pulmonary edema. LD are also frequently applied to patients with an acute decrease in glomerular filtration rate, namely, ... Read more >>

Kidney Blood Press Res (Kidney & blood pressure research)
[2019, 44(4):457-464]

Cited: 5 times

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Listen to your physiologist!

Philipp Hillmeister, Ivo Buschmann, Anja Bondke Persson,

Acta Physiol (Oxf) (Acta physiologica (Oxford, England))
[2019, 225(4):e13265]

Cited: 0 times

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Cardiovascular drugs attenuated myocardial resistance against ischaemia-induced and reperfusion-induced injury in a rat model of repetitive occlusion.

Nora Gatzke, Nadija Güc, Philipp Hillmeister, André Dülsner, Ferdinand Le Noble, Eva Elina Buschmann, Maja Ingwersen, Peter Bramlage, Ivo R Buschmann,

<h4>Objective</h4>We investigated the impact of cardioprotective drugs on ST-elevation, arrhythmias and infarct size in a rat model of repetitive coronary artery occlusion.<h4>Methods</h4>Seventy Sprague-Dawley rats were randomised to two control and five treatment groups. Placebo was either implantation of a pneumatic occluder onto the left anterior descending coronary artery (LAD) without ... Read more >>

Open Heart (Open heart)
[2018, 5(2):e000889]

Cited: 1 time

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Recanalization of bilateral axillaris/brachialis artery occlusion in a patient with Takayashu arteritis: First case report on using a novel drug-coated nitinol "chocolate" balloon catheter.

Mariatu Binta Leigh, Samad Kor, Petar Czantrak, Mesud Sacirovic, Nikolaos Pagonas, Philipp Hillmeister, Gabriele Zeidler, Peter Bramlage, Ivo Buschmann,

When fibrosis develops in Takayasu arteritis (TA), endovascular treatment may become necessary. A 63-year-old woman with TA underwent PTA with a nitinol-structured (chocolate-like) drug-coated balloon (C-DEB PTA). She remained in remission for >1 year. The case may foster research into the use of C-DEB PTA in TA. ... Read more >>

Clin Case Rep (Clinical case reports)
[2018, 6(12):2490-2494]

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Nitroglycerin application and coronary arteriogenesis.

Nora Gatzke, Philipp Hillmeister, André Dülsner, Nadija Güc, Rica Dawid, Katherine H Smith, Nikolaos Pagonas, Peter Bramlage, Michaela Gorath, Ivo R Buschmann,

BACKGROUND:In the presence of a coronary occlusion, pre-existing small collateral vessels (arterioles) develop into much larger arteries (biological bypasses) that have the potential to allow a certain level of perfusion distal to the blockage. Termed arteriogenesis, this phenomenon proceeds via a complex combination of events, with nitric oxide (NO) playing ... Read more >>

PLoS One (PloS one)
[2018, 13(8):e0201597]

Cited: 4 times

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A novel computer-aided diagnostic approach for detecting peripheral arterial disease in patients with diabetes.

Eva Elina Buschmann, Lulu Li, Michèle Brix, Andreas Zietzer, Philipp Hillmeister, Andreas Busjahn, Peter Bramlage, Ivo Buschmann,

Peripheral arterial disease (PAD) is an important manifestation of systemic atherosclerosis, with diabetes being one of its most significant risk factors. Owing to medial arterial calcification (MAC), the ankle-brachial index (ABI) is not always a reliable tool for detecting PAD. Arterial Doppler flow parameters, such as systolic maximal acceleration (ACCmax) ... Read more >>

PLoS One (PloS one)
[2018, 13(6):e0199374]

Cited: 2 times

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Cell-Based Therapies in Acute Kidney Injury (AKI).

Daniel Patschan, Ivo Buschmann, Oliver Ritter, Andreas Kribben,

Acute kidney injury frequently occurs in hospitalized patients all over the world. The prognosis remains poor since specific therapies for promoting kidney regeneration/repair are still missing. In recent years cell-based strategies have improved AKI outcomes under experimental circumstances. Four groups of cells, each of them displaying certain biological and functional ... Read more >>

Kidney Blood Press Res (Kidney & blood pressure research)
[2018, 43(3):673-681]

Cited: 7 times

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Induction of extracranial arteriogenesis by an arteriovenous fistula in a pig model.

Eva Elina Buschmann, Eun-Ji Lee, Dorit Jacobi, Anne-Katrin Woischnig, Susann Ulusans, Martin Schumacher, Katherine H Smith, Nikolaos Pagonas, Peter Bramlage, Joachim Klisch, Philipp Hillmeister, Ivo R Buschmann,

BACKGROUND AND AIMS:Arteriogenesis, the positive outward remodeling and growth of pre-existent collateral vessels, holds potential as a novel treatment for ischemic vascular disease. An extracranial arteriogenesis model in a pig will allow us to study molecular changes in a complex arteriolar network in a more clinically relevant large-animal model. To ... Read more >>

Atherosclerosis (Atherosclerosis)
[2018, 272:87-93]

Cited: 1 time

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Insights into coronary collateral formation from a novel porcine semiacute infarction model.

Florian Krackhardt, Jonathan M Harnoss, Matthias W Waliszewski, Zully Ritter, Susanne Granzow, Dieter Felsenberg, Konrad Neumann, Lilian O Lerman, Philipp Hillmeister, Rolf Gebker, Ingo Paetsch, Fabian Riediger, Peter Bramlage, Ivo R Buschmann,

BACKGROUND:For patients with severe ischemic heart disease, complete revascularization by a percutaneous coronary intervention or coronary artery bypass grafting is often not achieved and may still cause residual angina. In case of progressive coronary artery occlusions, therapeutic arteriogenesis constitutes a promising strategy for increasing blood supply to the ischemic myocardium. ... Read more >>

Coron Artery Dis (Coronary artery disease)
[2018, 29(2):127-137]

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A Triple Obstetric Challenge of Thoracopagus-Type Conjoined Twins, Eclampsia, and Obstructed Labor: A Case Report from Sub-Saharan Africa.

Mariatu Binta Leigh, Valerie John-Cole, Mike Kamara, Alimamy Philip Koroma, Michael Momoh Koroma, Edward Ejiro Emuveyan, Peter Bramlage, Ivo Buschmann,

Conjoined twins are very rarely seen. We present a case of thoracopagus that was undiagnosed prior to delivery and combined with eclampsia and obstructed labor in a low-resource setting in sub-Saharan Africa. A 27-year-old pregnant woman was presented to the maternity emergency unit of Princess Christian Maternity Hospital (PCMH) in ... Read more >>

Case Rep Obstet Gynecol (Case reports in obstetrics and gynecology)
[2017, 2017:6815748]

Cited: 1 time

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Usefulness of Individual Shear Rate Therapy, New Treatment Option for Patients With Symptomatic Coronary Artery Disease.

Frauke Picard, Petroula Panagiotidou, Ana Wolf-Pütz, Ivo Buschmann, Eva Buschmann, Maximilian Steffen, Rolf Michael Klein,

The aim of this study was to elucidate if patients with coronary artery disease (CAD), who fail to respond to revascularization procedures, can improve from individual shear rate therapy (ISRT). The ISRT is an adaptation of the external counterpulsation with lower individual treatment pressures based on Doppler-ultrasound measurements during counterpulsation. ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2018, 121(4):416-422]

Cited: 2 times

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Porcine arteriogenesis based on vasa vasorum in a novel semi-acute occlusion model using high-resolution imaging.

Jonathan M Harnoss, Florian Krackhardt, Zully Ritter, Susanne Granzow, Dieter Felsenberg, Konrad Neumann, Lilach O Lerman, Fabian Riediger, Philipp Hillmeister, Peter Bramlage, Ivo R Buschmann,

Bridging collaterals (BC) develop in several chronic total artery occlusion diseases, and can prevent extensive myocardial necrosis. Yet, their origin, growth process, and histo-morphology are still unclear. Since vasa vasorum (VV) may take part in collateralization, we hypothesized that VV are the basis for BCs. To comprehensively investigate this arteriogenesis ... Read more >>

Heart Vessels (Heart and vessels)
[2017, 32(11):1400-1409]

Cited: 3 times

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Long-term individual shear rate therapy counterpulsation enhances plasma nitrite release in patients with PAD.

Michèle Brix, Eva-Elina Buschmann, Andreas Zietzer, Jonnel Anthony Jaurigue, Lulu Li, Constantin Jungk, Ivo Buschmann, Doreen Janke, Philipp Hillmeister,

<h4>Background</h4>Individual shear rate therapy (ISRT) has been designed as a novel non-invasive treatment option for peripheral artery disease (PAD) patients and has been shown to improve endothelial function and walking distance. The aim of this study was to elucidate the impact of ISRT on the level of nitric oxide in ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2017, 46(1):37-45]

Cited: 2 times

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Adaptation of external counterpulsation based on individual shear rate therapy improves endothelial function and claudication distance in peripheral artery disease.

Eva-Elina Buschmann, Michele Brix, Lulu Li, Janke Doreen, Andreas Zietzer, Meijing Li, Ivo Buschmann, Philipp Hillmeister,

<h4>Background</h4>External counterpulsation therapy enhances blood flow and was shown to improve endothelial function and quality of life in coronary artery disease patients. However, high pressures of up to 300 mmHg may lead to malperfusion of the ischaemic limb. To improve the clinical outcome of patients with peripheral artery disease (PAD), ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2016, 45(4):317-324]

Cited: 4 times

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Role of short-acting nitroglycerin in the management of ischemic heart disease.

William E Boden, Santosh K Padala, Katherine P Cabral, Ivo R Buschmann, Mandeep S Sidhu,

Nitroglycerin is the oldest and most commonly prescribed short-acting anti-anginal agent; however, despite its long history of therapeutic usage, patient and health care provider education regarding the clinical benefits of the short-acting formulations in patients with angina remains under-appreciated. Nitrates predominantly induce vasodilation in large capacitance blood vessels, increase epicardial ... Read more >>

Drug Des Devel Ther (Drug design, development and therapy)
[2015, 9:4793-4805]

Cited: 10 times

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Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats.

Ivo Buschmann, Daniel Hackbusch, Nora Gatzke, André Dülsner, Manuela Trappiel, Markus Dagnell, Arne Ostman, Rob Hooft van Huijsduijnen, Kai Kappert,

<h4>Unlabelled</h4>Arteriogenesis involves the rapid proliferation of preexisting arterioles to fully functional arteries as a compensatory mechanism to overcome circulatory deficits. Stimulation of arteriogenesis has therefore been considered a treatment concept in arterial occlusive disease. Here, we investigated the impact of inhibition of protein tyrosine phosphatases (PTPs) on cerebral arteriogenesis in ... Read more >>

J Mol Med (Berl) (Journal of molecular medicine (Berlin, Germany))
[2014, 92(9):983-994]

Cited: 2 times

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Induction of cerebral arteriogenesis in mice.

André Duelsner, Nora Gatzke, Anja Bondke Persson, Ivo R Buschmann,

Unilateral common carotid artery occlusion (CCAO) is a standardized method to initiate collateral artery growth (arteriogenesis) in mouse brain. After CCAO is induced, blood circulation in the circle of Willis is changed and increases shear stress, which triggers increased arterial diameter and improvements in cerebrovascular reserve capacity. Functional improvement can ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2014, 1135:121-125]

Cited: 0 times

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