Full Text Journal Articles by
Author Ingrid M Libman

Advertisement

Find full text journal articles






Modern diabetes devices in the school setting: Perspectives from school nurses.

Christine A March, Michelle Nanni, Traci M Kazmerski, Linda M Siminerio, Elizabeth Miller, Ingrid M Libman,

OBJECTIVE:To explore the experiences, practices, and attitudes of school nurses related to modern diabetes devices (insulin pumps, continuous glucose monitors, and hybrid-closed loop systems). RESEARCH DESIGN AND METHODS:Semistructured interviews were conducted with 40 public school nurses caring for children in elementary and middle schools. Developed with stakeholder input, the interview ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2020, 21(5):832-840]

Cited: 0 times

View full text PDF listing >>



Excess BMI Accelerates Islet Autoimmunity in Older Children and Adolescents.

Christine Ferrara-Cook, Susan Michelle Geyer, Carmella Evans-Molina, Ingrid M Libman, Dorothy J Becker, Stephen E Gitelman, Maria Jose Redondo, ,

OBJECTIVE:Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. RESEARCH DESIGN AND METHODS:We studied 706 single autoantibody-positive pediatric TrialNet participants (ages 1.6-18.6 years at baseline). Cumulative ... Read more >>

Diabetes Care (Diabetes care)
[2020, 43(3):580-587]

Cited: 0 times

View full text PDF listing >>



Advertisement

Liraglutide in Children and Adolescents with Type 2 Diabetes.

William V Tamborlane, Margarita Barrientos-Pérez, Udi Fainberg, Helle Frimer-Larsen, Mona Hafez, Paula M Hale, Muhammad Y Jalaludin, Margarita Kovarenko, Ingrid Libman, Jane L Lynch, Paturi Rao, Naim Shehadeh, Serap Turan, Daniel Weghuber, Timothy Barrett, ,

BACKGROUND:Metformin is the regulatory-approved treatment of choice for most youth with type 2 diabetes early in the disease. However, early loss of glycemic control has been observed with metformin monotherapy. Whether liraglutide added to metformin (with or without basal insulin treatment) is safe and effective in youth with type 2 ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2019, 381(7):637-646]

Cited: 1 time

View full text PDF listing >>



Adiposity and Asthma in a Nationwide Study of Children and Adults in the United States.

Erick Forno, Yueh-Ying Han, Ingrid M Libman, Radhika H Muzumdar, Juan C Celedón,

RATIONALE:Although obesity has been associated with asthma, body mass index is suboptimal to fully characterize adiposity. OBJECTIVES:We examined the relation between adiposity and asthma in a large sample of the U.S. population, using indices defined by dual-energy X-ray absorptiometry. METHODS:We analyzed data from 8,886 children (aged 8-19 yr) and 12,795 ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2018, 15(3):322-330]

Cited: 6 times

View full text PDF listing >>



Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study.

Anna E Long, Isabel V Wilson, Dorothy J Becker, Ingrid M Libman, Vincent C Arena, F Susan Wong, Andrea K Steck, Marian J Rewers, Liping Yu, Peter Achenbach, Rosaura Casas, Johnny Ludvigsson, Alistair J K Williams, Kathleen M Gillespie,

AIMS/HYPOTHESIS:Multiple islet autoimmunity increases risk of diabetes, but not all individuals positive for two or more islet autoantibodies progress to disease within a decade. Major islet autoantibodies recognise insulin (IAA), GAD (GADA), islet antigen-2 (IA-2A) and zinc transporter 8 (ZnT8A). Here we describe the baseline characteristics of a unique cohort ... Read more >>

Diabetologia (Diabetologia)
[2018, 61(6):1484-1490]

Cited: 3 times

View full text PDF listing >>



The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1.

Jay M Sosenko, Susan Geyer, Jay S Skyler, Lisa E Rafkin, Heba M Ismail, Ingrid M Libman, Yuk-Fun Liu, Linda A DiMeglio, Carmella Evans-Molina, Jerry P Palmer,

BACKGROUND/OBJECTIVE:The extent of influence of BMI and age on C-peptide at the diagnosis of type 1 diabetes (T1D) is unknown. We thus studied the impact of body mass index Z-scores (BMIZ) and age on C-peptide measures at and soon after the diagnosis of T1D. METHODS:Data from Diabetes Prevention Trial-Type 1 ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2018, 19(3):403-409]

Cited: 3 times

View full text PDF listing >>



The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults.

Christine T Ferrara, Susan M Geyer, Carmella Evans-Molina, Ingrid M Libman, Dorothy J Becker, John M Wentworth, Antoinette Moran, Stephen E Gitelman, Maria J Redondo, ,

Background:Given the global rise in both type 1 diabetes incidence and obesity, the role of body mass index (BMI) on type 1 diabetes pathophysiology has gained great interest. Sustained excess BMI in pediatric participants of the TrialNet Pathway to Prevention (PTP) cohort increased risk for progression to type 1 diabetes, ... Read more >>

J. Clin. Endocrinol. Metab. (The Journal of clinical endocrinology and metabolism)
[2017, 102(12):4596-4603]

Cited: 3 times

View full text PDF listing >>



Insulin Sensitivity and Diabetic Kidney Disease in Children and Adolescents With Type 2 Diabetes: An Observational Analysis of Data From the TODAY Clinical Trial.

Petter Bjornstad, Edward Nehus, Laure El Ghormli, Fida Bacha, Ingrid M Libman, Siripoom McKay, Steven M Willi, Lori Laffel, Silva Arslanian, Kristen J Nadeau, ,

BACKGROUND:Diabetic kidney disease is a major cause of premature mortality in type 2 diabetes mellitus (T2DM). Worsening insulin sensitivity independent of glycemic control may contribute to the development of diabetic kidney disease. We investigated the longitudinal association of insulin sensitivity with hyperfiltration and increased albumin excretion in adolescents with T2DM. ... Read more >>

Am. J. Kidney Dis. (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2018, 71(1):65-74]

Cited: 6 times

View full text PDF listing >>



The shape of the glucose concentration curve during an oral glucose tolerance test predicts risk for type 1 diabetes.

Heba M Ismail, Ping Xu, Ingrid M Libman, Dorothy J Becker, Jennifer B Marks, Jay S Skyler, Jerry P Palmer, Jay M Sosenko, ,

AIMS/HYPOTHESIS:We aimed to examine: (1) whether specific glucose-response curve shapes during OGTTs are predictive of type 1 diabetes development; and (2) the extent to which the glucose-response curve is influenced by insulin secretion. METHODS:Autoantibody-positive relatives of people with type 1 diabetes whose baseline OGTT met the definition of a monophasic ... Read more >>

Diabetologia (Diabetologia)
[2018, 61(1):84-92]

Cited: 5 times

View full text PDF listing >>



Excess BMI in Childhood: A Modifiable Risk Factor for Type 1 Diabetes Development?

Christine Therese Ferrara, Susan Michelle Geyer, Yuk-Fun Liu, Carmella Evans-Molina, Ingrid M Libman, Rachel Besser, Dorothy J Becker, Henry Rodriguez, Antoinette Moran, Stephen E Gitelman, Maria J Redondo, ,

OBJECTIVE:We aimed to determine the effect of elevated BMI over time on the progression to type 1 diabetes in youth. RESEARCH DESIGN AND METHODS:We studied 1,117 children in the TrialNet Pathway to Prevention cohort (autoantibody-positive relatives of patients with type 1 diabetes). Longitudinally accumulated BMI above the 85th age- and ... Read more >>

Diabetes Care (Diabetes care)
[2017, 40(5):698-701]

Cited: 15 times

View full text PDF listing >>



Health Care Transition Preparation and Experiences in a U.S. National Sample of Young Adults With Type 1 Diabetes.

Katharine C Garvey, Nicole C Foster, Shivani Agarwal, Linda A DiMeglio, Barbara J Anderson, Sarah D Corathers, Marisa E Desimone, Ingrid M Libman, Sarah K Lyons, Anne L Peters, Jennifer K Raymond, Lori M Laffel,

OBJECTIVE:Young adults with type 1 diabetes transitioning from pediatric to adult care are at risk for adverse outcomes. We developed a survey to evaluate transition experiences in two groups of young adults with type 1 diabetes, before (PEDS) and after (ADULT) transition to adult care. RESEARCH DESIGN AND METHODS:We fielded ... Read more >>

Diabetes Care (Diabetes care)
[2017, 40(3):317-324]

Cited: 9 times

View full text PDF listing >>



Treatable Diabetic Retinopathy Is Extremely Rare Among Pediatric T1D Exchange Clinic Registry Participants.

Giovanna Beauchamp, Claire T Boyle, William V Tamborlane, Kellee M Miller, Ingrid M Libman, Michael J Haller, Roy W Beck, ,

Diabetes Care (Diabetes care)
[2016, 39(12):e218-e219]

Cited: 3 times

View full text PDF listing >>



Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical Trial.

Ingrid M Libman, Kellee M Miller, Linda A DiMeglio, Kathleen E Bethin, Michelle L Katz, Avni Shah, Jill H Simmons, Michael J Haller, Sripriya Raman, William V Tamborlane, Julie K Coffey, Ashleigh M Saenz, Roy W Beck, Kristen J Nadeau, ,

Previous studies assessing the effect of metformin on glycemic control in adolescents with type 1 diabetes have produced inconclusive results.To assess the efficacy and safety of metformin as an adjunct to insulin in treating overweight adolescents with type 1 diabetes.Multicenter (26 pediatric endocrinology clinics), double-blind, placebo-controlled randomized clinical trial involving ... Read more >>

JAMA (JAMA)
[2015, 314(21):2241-2250]

Cited: 53 times

View full text PDF listing >>



Hyponatremia due to Severe Primary Hypothyroidism in an Infant.

Nickolas T Agathis, Ingrid M Libman, Michael L Moritz,

Hyponatremia has been reported in the elderly with hypothyroidism and myxedema, but this has not been a universal finding in clinical studies and there have been only a few reports in children. We report a case of an infant who developed hyponatremia due to severe primary hypothyroidism. A 4-month-old ex-preterm ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2015, 3:96]

Cited: 2 times

View full text PDF listing >>



Prevalence of cardiovascular risk factors in youth with type 1 diabetes and elevated body mass index.

Maria J Redondo, Nicole C Foster, Ingrid M Libman, Sanjeev N Mehta, Joanne M Hathway, Kathleen E Bethin, Brandon M Nathan, Michelle A Ecker, Avni C Shah, Stephanie N DuBose, William V Tamborlane, Robert P Hoffman, Jenise C Wong, David M Maahs, Roy W Beck, Linda A DiMeglio,

The prevalence of cardiovascular risk factors in children with type 1 diabetes and elevated BMI in the USA is poorly defined. We aimed to test the hypothesis that children with type 1 diabetes who are overweight or obese have increased frequencies of hypertension, dyslipidemia, and micro-/macroalbuminuria compared to their healthy ... Read more >>

Acta Diabetol (Acta diabetologica)
[2016, 53(2):271-277]

Cited: 9 times

View full text PDF listing >>



Obesity, islet cell autoimmunity, and cardiovascular risk factors in youth at onset of type 1 autoimmune diabetes.

Maribel Cedillo, Ingrid M Libman, Vincent C Arena, Lei Zhou, Massimo Trucco, Diego Ize-Ludlow, Massimo Pietropaolo, Dorothy J Becker,

The current increase in childhood type 1 diabetes (T1D) and obesity has led to two conflicting hypotheses and conflicting reports regarding the effects of overweight on initiation and spreading of islet cell autoimmunity vs earlier clinical manifestation of preexisting autoimmune β-cell damage driven by excess weight.The objective of the study ... Read more >>

J. Clin. Endocrinol. Metab. (The Journal of clinical endocrinology and metabolism)
[2015, 100(1):E82-6]

Cited: 9 times

View full text PDF listing >>



Relationship of adiponectin and leptin with autoimmunity in children with new-onset type 1 diabetes: a pilot study.

Natalie Hecht Baldauff, Hala Tfayli, Wenxiu Dong, Vincent C Arena, Nursen Gurtunca, Massimo Pietropaolo, Dorothy J Becker, Ingrid M Libman,

To explore racial differences in adiponectin, and leptin and their relationship with islet autoimmunity in children with new-onset type 1 diabetes (T1D).Medical records were reviewed from a cohort of new-onset clinically diagnosed T1D subjects matched by race, age, gender, and year of diagnosis. Sera were available for 156 subjects (77 ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2016, 17(4):249-256]

Cited: 2 times

View full text PDF listing >>



Clinical review: Diabetes in the adolescent: transitional issues.

Sarah K Lyons, Ingrid M Libman, Mark A Sperling,

Orchestrating a seamless transition from pediatric to adult care can be a daunting task in caring for youth with diabetes mellitus. This clinical review focuses on physical and psychosocial aspects affecting the care of adolescents and young adults with diabetes, evaluates how these aspects can be barriers in the process ... Read more >>

J. Clin. Endocrinol. Metab. (The Journal of clinical endocrinology and metabolism)
[2013, 98(12):4639-4645]

Cited: 21 times

View full text PDF listing >>



Most youth with type 1 diabetes in the T1D Exchange Clinic Registry do not meet American Diabetes Association or International Society for Pediatric and Adolescent Diabetes clinical guidelines.

Jamie R Wood, Kellee M Miller, David M Maahs, Roy W Beck, Linda A DiMeglio, Ingrid M Libman, Maryanne Quinn, William V Tamborlane, Stephanie E Woerner, ,

To assess the proportion of youth with type 1 diabetes under the care of pediatric endocrinologists in the United States meeting targets for HbA1c, blood pressure (BP), BMI, and lipids.Data were evaluated for 13,316 participants in the T1D Exchange clinic registry younger than 20 years old with type 1 diabetes ... Read more >>

Diabetes Care (Diabetes care)
[2013, 36(7):2035-2037]

Cited: 175 times

View full text PDF listing >>



β-cell autoimmunity in overweight non-diabetic youth: any implications?

Ingrid M Libman, E Barinas-Mitchell, S Marcovina, F Bacha, T Hannon, H Tfayli, S J Lee, S Bansal, R Robertson, S Arslanian,

BACKGROUND AND OBJECTIVE:The presence of β-cell antibodies is associated with a high risk of type 1 diabetes. With increasing rates of obesity, the distinction between obese T1DM and T2DM has become difficult. Moreover, increasing body mass index (BMI) in at-risk children has been proposed not only as a possible contributor ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2011, 12(3 Pt 2):207-211]

Cited: 3 times

View full text PDF listing >>



Fasting and 2-hour plasma glucose and insulin: relationship with risk factors for cardiovascular disease in overweight nondiabetic children.

Ingrid M Libman, Emma Barinas-Mitchell, Andrea Bartucci, Diego Chaves-Gnecco, Robert Robertson, Silva Arslanian,

To determine whether elevated fasting or 2-h plasma glucose and/or insulin better reflects the presence of cardiovascular disease (CVD) risk markers in an overweight pediatric population with normal glucose tolerance.A total of 151 overweight youths (8-17 years old) were evaluated with oral glucose tolerance tests and measurement of CVD risk ... Read more >>

Diabetes Care (Diabetes care)
[2010, 33(12):2674-2676]

Cited: 10 times

View full text PDF listing >>



Thyroid autoimmunity in children with features of both type 1 and type 2 diabetes.

Ingrid M Libman, Kang Sun, Thomas P Foley, Dorothy J Becker,

AIM/HYPOTHESIS: To assess the prevalence of autoimmune thyroid disease (ATD) in insulin-treated youth with clinical features of type 2 diabetes mellitus (T2DM). METHODS: We evaluated prevalence of thyroid peroxidase (TPO) and thyroglobulin (TGA) antibodies at onset of insulin-treated diabetes and follow-up in 183 White and Black children. Of these, 136 ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2008, 9(4 Pt 1):266-271]

Cited: 8 times

View full text PDF listing >>



Increased Expression of Monocyte CD11b (Mac-1) in Overweight Recent-Onset Type 1 Diabetic Children.

Vincenza Cifarelli, Ingrid M Libman, Angela Deluca, Dorothy Becker, Massimo Trucco, Patrizia Luppi,

AIM:Compelling evidence implicates inflammation in the pathogenesis of type 1 diabetes mellitus (T1DM) and associated vascular complications. Obesity is also characterized by low-grade systemic inflammation. In this study, we characterized the inflammatory response in diabetes by analyzing the expression of a panel of activation markers on the surface of peripheral ... Read more >>

Rev Diabet Stud (The review of diabetic studies : RDS)
[2007, 4(2):112-117]

Cited: 14 times

View full text PDF listing >>



Prevention and treatment of type 2 diabetes in youth.

Ingrid M Libman, Silva A Arslanian,

Parallel to the increase in obesity worldwide, there has been a rise in the prevalence of type 2 diabetes mellitus (T2DM) in children and adolescents. The etiology of T2DM in youth, similar to adults, is multifactorial including genetic and environmental factors, among them obesity, sedentary lifestyle, family history of the ... Read more >>

Horm. Res. (Hormone research)
[2007, 67(1):22-34]

Cited: 19 times

View full text PDF listing >>



Changing trends in epidemiology of type 1 diabetes mellitus throughout the world: how far have we come and where do we go from here.

Ingrid M Libman, Ronald E LaPorte,

Pediatr Diabetes (Pediatric diabetes)
[2005, 6(3):119-121]

Cited: 8 times

View full text PDF listing >>



Advertisement

Disclaimer
1.8745 s