Full Text Journal Articles by
Author Ingrid Glurich

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DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter.

Keke Shao, Weilin Pu, Jianfeng Zhang, Shicheng Guo, Fei Qian, Ingrid Glurich, Qing Jin, Yanyun Ma, Shaoqing Ju, Zhao Zhang, Weifeng Ding,

<h4>Background</h4>Aberrant DNA methylation has been firmly established as a factor contributing to the pathogenesis of colorectal cancer (CRC) via its capacity to silence tumour suppressor genes. However, the methylation status of multiple tumour suppressor genes and their roles in promoting CRC metastasis are not well characterised.<h4>Methods</h4>We explored the methylation and ... Read more >>

Clin Epigenetics (Clinical epigenetics)
[2021, 13(1):89]

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Knowledge, Attitudes, Behaviors of Women Related to Pregnancy, and Early Childhood Caries Prevention: A Cross-Sectional Pilot Study.

Neel Shimpi, Ingrid Glurich, Catherine Maybury, Min Qi Wang, Kazumasa Hashimoto, Amit Acharya, Alice M Horowitz,

<h4>Objective</h4>Health education interventions during pregnancy can influence maternal oral health (OH), maternal OH-behaviors and children's OH. Interventions that can be delivered at anytime and anywhere, for example mobile-health (mHealth) provides an opportunity to address challenges of health education and support activation of women in underserved and rural communities to modify ... Read more >>

J Prim Care Community Health (Journal of primary care & community health)
[2021, 12:21501327211013302]

Cited: 0 times

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Positioning operations in the dental safety net to enhance value-based care delivery in an integrated health-care setting.

Gregory Nycz, Neel Shimpi, Ingrid Glurich, Megan Ryan, Gwen Sova, Sarah Weiner, Laurie Nichols, Amit Acharya,

<h4>Objectives</h4>Impact of implementing data-driven performance metric-tracking across a 10-dental center infrastructure established by Family Heath Center of Marshfield (FHC-M) was examined for relative impact on achieving value-based care delivery in serving a patient population characterized by 88% Medicaid representation.<h4>Methods</h4>To track progress toward national benchmarks for preventive care delivery, dental quality ... Read more >>

J Public Health Dent (Journal of public health dentistry)
[2020, 80 Suppl 2:S71-S76]

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The case for integrated oral and primary medical health care delivery: Marshfield Clinic Health System.

R Lamont Monty MacNeil, Helena Hilario, Megan M Ryan, Ingrid Glurich, Greg R Nycz, Amit Acharya,

J Dent Educ (Journal of dental education)
[2020, 84(8):924-931]

Cited: 0 times

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World Workshop on Oral Medicine VII: Prognostic biomarkers in oral leukoplakia and proliferative verrucous leukoplakia-A systematic review of retrospective studies.

Antonio Celentano, Ingrid Glurich, Wenche S Borgnakke, Camile S Farah,

<h4>Objective</h4>To systematically review retrospective studies examining prognostic potentials of candidate biomarkers to stratify malignant progression of oral leukoplakia (OL) and proliferative verrucous leukoplakia (PVL).<h4>Materials and methods</h4>A systematic literature search of PubMed, EMBASE, Evidence-Based Medicine and Web of Science databases targeted literature published through 29 March 2018. Inter-rater agreement was ascertained ... Read more >>

Oral Dis (Oral diseases)
[2021, 27(4):848-880]

Cited: 4 times

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Correlation Between Oral Health and Systemic Inflammation (COHESION): A Randomized Pilot Follow-Up Trial of a Plaque-Identifying Toothpaste.

Amit Acharya, Ingrid Glurich, Scott Hetzel, KyungMann Kim, Matthew C Tattersall, David L DeMets, Charles H Hennekens,

<h4>Background</h4>Inflammation is intimately involved in the pathogenesis of atherosclerosis and is accurately measured by high-sensitivity C-reactive protein (hs-CRP), a sensitive marker for future risk of cardiovascular disease. The Correlation between Oral Health and Systemic Inflammation (COHESION) trial was designed to test the hypothesis that PlaqueHD, a plaque-identifying toothpaste, reduces hs-CRP.<h4>Methods</h4>The ... Read more >>

Am J Med (The American journal of medicine)
[2020, 133(8):994-998]

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KIAA1217: A novel candidate gene associated with isolated and syndromic vertebral malformations.

Noura Al Dhaheri, Nan Wu, Sen Zhao, Zhihong Wu, Robert D Blank, Jianguo Zhang, Cathy Raggio, Matthew Halanski, Jianxiong Shen, Ken Noonan, Guixing Qiu, Blaise Nemeth, Sarah Sund, Sally L Dunwoodie, Gavin Chapman, Ingrid Glurich, Robert D Steiner, Elizabeth Wohler, Renan Martin, Nara Lygia Sobreira, Philip F Giampietro,

Vertebral malformations (VMs) are caused by alterations in somitogenesis and may occur in association with other congenital anomalies. The genetic etiology of most VMs remains unknown and their identification may facilitate the development of novel therapeutic and prevention strategies. Exome sequencing was performed on both the discovery cohort of nine ... Read more >>

Am J Med Genet A (American journal of medical genetics. Part A)
[2020, 182(7):1664-1672]

Cited: 3 times

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Solutions to dental access disparity: Blueprint of an innovative community health center-based model for rurally based communities.

Gregory Nycz, Amit Acharya, Ingrid Glurich,

Dr. David Satcher issued the first Surgeon General Report on oral health in the United States in 2000, drawing attention to a prevailing oral health access crisis. Dr. Satcher's report resonated in Wisconsin where a statewide growing dental access crisis was in progress and inspired grassroots efforts by a Family ... Read more >>

J Public Health Dent (Journal of public health dentistry)
[2020, 80(1):4-8]

Cited: 0 times

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Response to "prognostic biomarkers in oral leukoplakia".

Alessandro Villa, Antonio Celentano, Ingrid Glurich, Wenche S Borgnakke, Siri Beier Jensen, Douglas E Peterson, Konstantina Delli, David Ojeda, Arjan Vissink, Camile S Farah,

Oral Dis (Oral diseases)
[2019, 25(8):2048-2049]

Cited: 0 times

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Development of non-invasive diabetes risk prediction models as decision support tools designed for application in the dental clinical environment.

Harshad Hegde, Neel Shimpi, Aloksagar Panny, Ingrid Glurich, Pamela Christie, Amit Acharya,

The objective was to develop a predictive model using medical-dental data from an integrated electronic health record (iEHR) to identify individuals with undiagnosed diabetes mellitus (DM) in dental settings. Retrospective data retrieved from Marshfield Clinic Health System's data-warehouse was pre-processed prior to conducting analysis. A subset was extracted from the ... Read more >>

Inform Med Unlocked (Informatics in medicine unlocked)
[2019, 17:]

Cited: 1 time

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Updates from the Evidence Base Examining Association between Periodontal Disease and Type 2 Diabetes Mellitus: Current Status and Clinical Relevance.

Ingrid Glurich, Amit Acharya,

PURPOSE OF THE REVIEW:Epidemiological surveillance documents an escalating epidemic prevalence of both type 2 diabetes (T2DM) and periodontal disease (PD). The principal goals of this review are to: 1) re-examine the clinical significance of associations between PD and T2DM, based on strength of collective evidence as determined by systematic review ... Read more >>

Curr Diab Rep (Current diabetes reports)
[2019, 19(11):121]

Cited: 4 times

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Knowledgeability, attitude, and practice behaviors of primary care providers toward managing patients' oral health care in medical practice: Wisconsin statewide survey.

Neel Shimpi, Ingrid Glurich, Aloksagar Panny, Amit Acharya,

<h4>Background</h4>In this study, the authors sought to explore the receptivity, preparedness, and rates of adoption of integrated medical-dental models of care (MOCs) in the practice setting among primary care providers (PCPs) treating patients with diabetes mellitus (DM).<h4>Methods</h4>The authors conducted an anonymous statewide survey targeting PCPs across a range of Wisconsin-based ... Read more >>

J Am Dent Assoc (Journal of the American Dental Association (1939))
[2019, 150(10):863-872]

Cited: 2 times

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World Workshop on Oral Medicine VII: Prognostic biomarkers in oral leukoplakia: A systematic review of longitudinal studies.

Alessandro Villa, Antonio Celentano, Ingrid Glurich, Wenche S Borgnakke, Siri Beier Jensen, Douglas E Peterson, Konstantina Delli, David Ojeda, Arjan Vissink, Camile S Farah,

<h4>Objective</h4>To identify the prognostic biomarker candidates for stratification and long-term surveillance of oral leukoplakia progressing to cancer via a systematic literature review.<h4>Materials and methods</h4>Systematic searches with no date restrictions were conducted on March 29, 2018, targeting the databases PubMed (Ovid), EMBASE (Ovid), EBM (Ovid), and Web of Science (ISI). Bias ... Read more >>

Oral Dis (Oral diseases)
[2019, 25 Suppl 1:64-78]

Cited: 7 times

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World Workshop on Oral Medicine VII: Biomarkers predicting lymphoma in the salivary glands of patients with Sjögren's syndrome-A systematic review.

Konstantina Delli, Alessandro Villa, Camile S Farah, Antonio Celentano, David Ojeda, Douglas E Peterson, Siri B Jensen, Ingrid Glurich, Arjan Vissink,

<h4>Objective</h4>To conduct a systematic review of studies exploring potential biomarkers for development, course, and efficacy of treatment of lymphomas in salivary glands of patients with Sjögren's syndrome.<h4>Material and methods</h4>Eligible studies were identified through a comprehensive search of two databases, that is, PubMed and EMBASE. Quality of included articles was assessed ... Read more >>

Oral Dis (Oral diseases)
[2019, 25 Suppl 1:49-63]

Cited: 5 times

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Patient Awareness of Association of Diabetes and Periodontal Disease.

Neel Shimpi, Ingrid Glurich, Dixie Schroeder, Callahan Katrak, Po-Huang Chyou, Amit Acharya,

This cross-sectional study sought to assess the current awareness, knowledge, and behavior regarding diabetes mellitus (DM) and periodontal disease (PD) association among a convenience sample of patients from a large Wisconsin-based integrated medical-dental health care organization serving largely rurally based communities. An anonymous 10-question survey was distributed at regional medical ... Read more >>

Health Promot Pract (Health promotion practice)
[2020, 21(3):464-472]

Cited: 0 times

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Patient awareness/knowledge towards oral cancer: a cross-sectional survey.

Neel Shimpi, Monica Jethwani, Aditi Bharatkumar, Po-Huang Chyou, Ingrid Glurich, Amit Acharya,

BACKGROUND:Oral cancer (OC) is associated with multiple risk factors and high mortality rates and substantially contributes to the global cancer burden despite being highly preventable. This cross-sectional study sought to assess current knowledge, awareness, and behaviors of patients in rural communities surrounding OC risk. METHODS:An anonymous 21-question survey was distributed ... Read more >>

BMC Oral Health (BMC oral health)
[2018, 18(1):86]

Cited: 3 times

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Screening for dysglycaemia in dental primary care practice settings: systematic review of the evidence.

Ingrid Glurich, Barbara Bartkowiak, Richard L Berg, Amit Acharya,

INTRODUCTION:Increasing prevalence of diabetes and periodontal disease is prompting identification of additional clinical settings to identify patients at risk for dysglycaemia. A systematic review of studies that have examined feasibility of screening for at-risk patients in general dentistry settings at point-of-care (POC) was undertaken. MATERIALS AND METHODS:Systematic review of pragmatic ... Read more >>

Int Dent J (International dental journal)
[2018, 68(6):369-377]

Cited: 2 times

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Knowledgeability, Attitude and Behavior of Primary Care Providers Towards Oral Cancer: a Pilot Study.

Neel Shimpi, Aditi Bharatkumar, Monica Jethwani, Po-Huang Chyou, Ingrid Glurich, Jake Blamer, Amit Acharya,

The objective of this study was to assess current knowledgeability, attitudes, and practice behaviors of primary care providers (PCPs) towards oral cancer screening. Applying a cross-sectional design, a 14-question survey was emailed to 307 PCPs practicing at a large, multi-specialty, rurally based healthcare system. Survey data were collected and managed ... Read more >>

J Cancer Educ (Journal of cancer education : the official journal of the American Association for Cancer Education)
[2018, 33(2):359-364]

Cited: 5 times

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Need for diagnostic-centric care in dentistry: A case study from the Marshfield Clinic Health System.

Neel Shimpi, Zhan Ye, Rajesh Koralkar, Ingrid Glurich, Amit Acharya,

BACKGROUND:The study objective was to evaluate the workflow of dental providers who use the existing electronic dental record (EDR) system at a large regional health care system to establish a diagnostic-centric culture as part of their dental practice. A further goal focused on identifying when improvements to the workflow and design ... Read more >>

J Am Dent Assoc (Journal of the American Dental Association (1939))
[2018, 149(2):122-131]

Cited: 2 times

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Tobacco use status from clinical notes using Natural Language Processing and rule based algorithm.

Harshad Hegde, Neel Shimpi, Ingrid Glurich, Amit Acharya,

<h4>Background</h4>This cross-sectional retrospective study utilized Natural Language Processing (NLP) to extract tobacco-use associated variables from clinical notes documented in the Electronic Health Record (EHR).<h4>Objecitve</h4>To develop a rule-based algorithm for determining the present status of the patient's tobacco-use.<h4>Methods</h4>Clinical notes (n= 5,371 documents) from 363 patients were mined and classified by NLP ... Read more >>

Technol Health Care (Technology and health care : official journal of the European Society for Engineering and Medicine)
[2018, 26(3):445-456]

Cited: 1 time

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Integrating Medical-Dental Care for Diabetic Patients: Qualitative Assessment of Provider Perspectives.

Ingrid Glurich, Kelsey M Schwei, Sara Lindberg, Neel Shimpi, Amit Acharya,

Globally, periodontal disease and diabetes have achieved epidemic proportions and have become a top health care priority. Mutual bidirectional exacerbation of these conditions is promoting creation of cross-disciplinary integrated care delivery (ICD) models that bridge the traditionally siloed health care domains of dentistry and medicine. By engaging focus groups inclusive ... Read more >>

Health Promot Pract (Health promotion practice)
[2018, 19(4):531-541]

Cited: 4 times

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Status Update on Translation of Integrated Primary Dental-Medical Care Delivery for Management of Diabetic Patients.

Ingrid Glurich, Gregory Nycz, Amit Acharya,

Escalating prevalence of both diabetes and periodontal disease, two diseases associated with bi-directional exacerbation, has been reported. Periodontal disease represents a modifiable risk factor that may reduce diabetes onset or progression, and integrated models of cross-disciplinary care are needed to establish and manage glycemic control in affected patients. An ad-hoc ... Read more >>

Clin Med Res (Clinical medicine & research)
[2017, 15(1-2):21-32]

Cited: 5 times

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Medical Providers' Oral Health Knowledgeability, Attitudes, and Practice Behaviors: An Opportunity for Interprofessional Collaboration.

Neel Shimpi, Dixie Schroeder, Joseph Kilsdonk, Po-Huang Chyou, Ingrid Glurich, Eric Penniman, Amit Acharya,

<h4>Objective</h4>Evaluation of current knowledgeability, attitudes, and practice behaviors of medical providers from a large health care system toward oral health was undertaken as a pilot effort to better understand and integrate oral health into the overall health care delivery.<h4>Methods</h4>Invitations to complete a 28-question survey, designed in a web-based platform (SurveyMonkey(®)), ... Read more >>

J Evid Based Dent Pract (The journal of evidence-based dental practice)
[2016, 16(1):19-29]

Cited: 14 times

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Progress in oral personalized medicine: contribution of 'omics'.

Ingrid Glurich, Amit Acharya, Murray H Brilliant, Sanjay K Shukla,

BACKGROUND:Precision medicine (PM), representing clinically applicable personalized medicine, proactively integrates and interprets multidimensional personal health data, including clinical, 'omics', and environmental profiles, into clinical practice. Realization of PM remains in progress. OBJECTIVE:The focus of this review is to provide a descriptive narrative overview of: 1) the current status of oral ... Read more >>

J Oral Microbiol (Journal of oral microbiology)
[2015, 7:28223]

Cited: 1 time

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Type 2 diabetes mellitus, glycemic control, and cancer risk.

Adedayo A Onitilo, Rachel V Stankowski, Richard L Berg, Jessica M Engel, Ingrid Glurich, Gail M Williams, Suhail A Doi,

Type 2 diabetes mellitus is characterized by prolonged hyperinsulinemia, insulin resistance, and progressive hyperglycemia. Disease management relies on glycemic control through diet, exercise, and pharmacological intervention. The goal of the present study was to examine the effects of glycemic control and the use of glucose-lowering medication on the risk of ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2014, 23(2):134-140]

Cited: 35 times

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