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Author Huijun Wang

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Elevated Fat Intake Increases Body Weight and the Risk of Overweight and Obesity among Chinese Adults: 1991-2015 Trends.

Liang Wang, Huijun Wang, Bing Zhang, Barry M Popkin, Shufa Du,

Studies on fat intake and obesity have been inconclusive. This study examined the associations between dietary fat intake and body weight and the risk of overweight and obesity in China. We used data from 23,859 adults aged 20-60 years who participated in the China Health and Nutrition Survey, an ongoing ... Read more >>

Nutrients (Nutrients)
[2020, 12(11):]

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Associations of sodium and potassium consumption with the gut microbiota and host metabolites in a population-based study in Chinese adults.

Yiqing Wang, Huijun Wang, Annie Green Howard, Matthew C B Tsilimigras, Christy L Avery, Katie A Meyer, Wei Sha, Shan Sun, Jiguo Zhang, Chang Su, Zhihong Wang, Bing Zhang, Anthony A Fodor, Penny Gordon-Larsen,

BACKGROUND:There is increasing evidence that sodium consumption alters the gut microbiota and host metabolome in murine models and small studies in humans. However, there is a lack of population-based studies that capture large variations in sodium consumption as well as potassium consumption. OBJECTIVE:We examined the associations of energy-adjusted dietary sodium ... Read more >>

Am J Clin Nutr (The American journal of clinical nutrition)
[2020, :]

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Evaluation of emission reduction targets contributed by BASIC countries from the perspective of global temperature control targets.

Huijun Wang, Yong Wang, Lin Qi,

In this paper, the BASIC (Brazil, South Africa, India, and China) countries, which play an increasingly significant role in combating climate change, are selected as the research objects. First, we investigate the driving factors of the evolution of carbon emissions in the BASIC group from 2000 to 2016. Second, we ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2020, :]

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Publisher Correction: A mass spectrometry-based proteome map of drug action in lung cancer cell lines.

Benjamin Ruprecht, Julie Di Bernardo, Zhao Wang, Xuan Mo, Oleg Ursu, Matthew Christopher, Rafael B Fernandez, Li Zheng, Brian D Dill, Huijun Wang, Yuting Xu, Andy Liaw, Jonathan D Mortison, Nirodhini Siriwardana, Brian Andresen, Meir Glick, James R Tata, Victoria Kutilek, Ivan Cornella-Taracido, An Chi,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nat Chem Biol (Nature chemical biology)
[2020, 16(10):1149]

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Disparities in fresh fruit and vegetable intake by sociodemographic and behavioural factors among adults in China.

Li Li, Yifei Ouyang, Huijun Wang, Feifei Huang, Yun Wang, Jiguo Zhang, Chang Su, Wenwen Du, Xiaofang Jia, Hongru Jiang, Zhihong Wang, Bing Zhang,

OBJECTIVE:To measure the associations of sociodemographic and behavioural factors with fruit and vegetable consumption among adults in China. DESIGN:A cross-sectional study. SETTING:A 2015 wave of the China Health and Nutrition Survey. PARTICIPANTS:Totally, 11 910 adults aged 18 to 64 years. RESULTS:Adjusted log binomial regression analyses showed that adults with higher ... Read more >>

Public Health Nutr (Public health nutrition)
[2020, :1-8]

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Efficacy and safety of CD19 CAR T constructed with a new anti-CD19 chimeric antigen receptor in relapsed or refractory acute lymphoblastic leukemia.

Runxia Gu, Fang Liu, Dehui Zou, Yingxi Xu, Yang Lu, Bingcheng Liu, Wei Liu, Xiaojuan Chen, Kaiqi Liu, Ye Guo, Xiaoyuan Gong, Rui Lv, Xia Chen, Chunlin Zhou, Mengjun Zhong, Huijun Wang, Hui Wei, Yingchang Mi, Lugui Qiu, Lulu Lv, Min Wang, Ying Wang, Xiaofan Zhu, Jianxiang Wang,

BACKGROUND:Recent evidence suggests that resistance to CD19 chimeric antigen receptor (CAR)-modified T cell therapy may be due to the presence of CD19 isoforms that lose binding to the single-chain variable fragment (scFv) in current use. As such, further investigation of CARs recognize different epitopes of CD19 antigen may be necessary. ... Read more >>

J Hematol Oncol (Journal of hematology & oncology)
[2020, 13(1):122]

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Tonsillar fat herniation: A novel finding in Goltz syndrome.

Zijuan Wang, Huijun Wang, Zhimiao Lin,

Indian J Dermatol Venereol Leprol (Indian journal of dermatology, venereology and leprology)
[2020, :]

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A Novel, Recurrent, 3.6-kb Deletion in the PYGL Gene Contributes to Glycogen Storage Disease Type VI.

Bo Liu, Bingbing Wu, Yi Lu, Ping Zhang, Feifan Xiao, Gang Li, Huijun Wang, Xinran Dong, Renchao Liu, Yuchuan Li, Xinbao Xie, Wenhao Zhou, Jianshe Wang, Yulan Lu,

The PYGL gene is the only established gene known to cause glycogen storage disease type VI (GSD6), which is a rare autosomal recessive disorder associated with hepatomegaly, elevated levels of hepatic transaminases, and hypoglycemia. Extended bioinformatics analysis was performed on the exome sequencing data of 5 patients who were clinically ... Read more >>

J Mol Diagn (The Journal of molecular diagnostics : JMD)
[2020, :]

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Urbanization in China is associated with pronounced perturbation of plasma metabolites.

Yiqing Wang, Wei Sha, Huijun Wang, Annie Green Howard, Matthew C B Tsilimigras, Jiguo Zhang, Chang Su, Zhihong Wang, Bing Zhang, Anthony A Fodor, Penny Gordon-Larsen,

INTRODUCTION:Urbanization is associated with major changes in environmental and lifestyle exposures that may influence metabolic signatures. OBJECTIVES:We investigated cross-sectional urban and rural differences in plasma metabolome analyzed by liquid chromatography/mass spectrometry platform in 500 Chinese adults aged 25-68 years from two neighboring southern Chinese provinces. METHODS:We first examined the overall metabolome ... Read more >>

Metabolomics (Metabolomics : Official journal of the Metabolomic Society)
[2020, 16(10):103]

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Intra-Individual Double Burden of Malnutrition among Adults in China: Evidence from the China Health and Nutrition Survey 2015.

Qiumin Huang, Liusen Wang, Hongru Jiang, Huijun Wang, Bing Zhang, Jiguo Zhang, Xiaofang Jia, Zhihong Wang,

Few studies have focused on quantifying the double burden of malnutrition (DBM) phenomenon in China. We aimed to clarify the prevalence of DBM among Chinese adults as well as to examine whether usual daily dietary micronutrient status varies by body mass index (BMI) categories. In this study, a sample of ... Read more >>

Nutrients (Nutrients)
[2020, 12(9):]

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Early diagnosis of WT1 nephropathy and follow up in a Chinese multicenter cohort.

Shuzhen Sun, Linan Xu, Yunli Bi, Jing Wang, Zhiqing Zhang, Xiaoshan Tang, Qi Cao, Yihui Zhai, Jing Chen, Xiaoyan Fang, Jialu Liu, Ye Fang, Tianchao Xiang, Yanyan Qian, Bingbing Wu, Huijun Wang, Wenhao Zhou, Jian Shen, Kuiran Dong, Xiaorong Liu, Bixia Zheng, Aihua Zhang, Xiaowen Wang, Yubing Wu, Duan Ma, Qian Shen, Jia Rao, Hong Xu,

BACKGROUND:WT1 mutations cause a wide spectrum of renal and extrarenal manifestations concerning urogenital development and the development of tumors. METHODS:We retrospectively collected the information on the genotype and phenotype of WT1 nephropathy from the multicenter registry since 2014 to 2019. All patients were stratified by renal function decline status or ... Read more >>

Eur J Med Genet (European journal of medical genetics)
[2020, 63(11):104047]

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Genotype-Phenotype Correlation of TRPV3-Related Olmsted Syndrome.

Weilong Zhong, Linghan Hu, Xu Cao, Jiahui Zhao, Xianning Zhang, Mingyang Lee, Huijun Wang, Jie Zhang, Quan Chen, Cheng Feng, Lina Duo, Xiuli Wang, Li Tang, Zhimiao Lin, Yong Yang,

We have previously shown that gain-of-function mutations in TRPV3 underlay Olmsted syndrome (OS), a rare hyperkeratotic skin channelopathy. Here, we attempt to establish a genotype-phenotype correlation in OS, which has been unclear due to the rarity and heterogeneity of the condition. We identified five previously unreported TRPV3 mutations (R416Q, R416W, ... Read more >>

J. Invest. Dermatol. (The Journal of investigative dermatology)
[2020, :]

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Energy intake and energy contributions of macronutrients and major food sources among Chinese adults: CHNS 2015 and CNTCS 2015.

Hongru Jiang, Ji Zhang, Wenwen Du, Chang Su, Bing Zhang, Huijun Wang,

BACKGROUND:Excessive energy intake and unbalanced food choices are major health concerns associated with obesity and related chronic diseases. This study evaluates the levels of dietary energy intake and the energy contributions of macronutrients, major food sources, and various eating occasions and processed food among Chinese adults. METHODS:The study examined a ... Read more >>

Eur J Clin Nutr (European journal of clinical nutrition)
[2020, :]

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Circulating Short-Chain Fatty Acids Are Positively Associated with Adiposity Measures in Chinese Adults.

Yiqing Wang, Huijun Wang, Annie Green Howard, Katie A Meyer, Matthew C B Tsilimigras, Christy L Avery, Wei Sha, Shan Sun, Jiguo Zhang, Chang Su, Zhihong Wang, Bing Zhang, Anthony A Fodor, Penny Gordon-Larsen,

Epidemiological studies suggest a positive association between obesity and fecal short-chain fatty acids (SCFAs) produced by microbial fermentation of dietary carbohydrates, while animal models suggest increased energy harvest through colonic SCFA production in obesity. However, there is a lack of human population-based studies with dietary intake data, plasma SCFAs, gut ... Read more >>

Nutrients (Nutrients)
[2020, 12(7):]

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Nutrition transition and related health challenges over decades in China.

Lina Huang, Zhihong Wang, Huijun Wang, Liyun Zhao, Hongru Jiang, Bing Zhang, Gangqiang Ding,

Since the Opening of China, the country's economy has continuously and rapidly improved. Various economic, educational, and health policies have been implemented to shape the development of society, which may have greatly affected the Chinese diet and related malnutrition issues. The objective of the present review was to comprehensively review ... Read more >>

Eur J Clin Nutr (European journal of clinical nutrition)
[2020, :]

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[Analysis of genetic and environmental risk factors in pediatric OSA].

Huijun Wang, Yanru Li, Fei Gao, Guoqiang Zhao, Minmin Su, Dan Kang, Wen Xu, Demin Han,

Objective:To investigate the genetic and family environmental risk factors of obstructive sleep apnea(OSA) in children with habitual snoring. Method:Children with habitual snoring who underwent overnight PSG were recruited. Subjects were divided into the snoring group and OSA group according to the criteria of the International Classification of Sleep Disorder(ICSD-3). The ... Read more >>

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery)
[2020, 34(8):678-682]

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[Feasibility analysis of new dry electrode EEG sleep monitoring].

Pengfei Ye, Yanru Li, Xingjun Wang, Xiu Ding, Dan Kang, Hongguang Li, Huijun Wang, Adhikari Sharma, Wen Xu, Demin Han,

Objective:To evaluate the accuracy of the new carbon black polyurethane dry electrode electroencephalogram and clarify the value of the new dry electrode electroencephalogram. Method:Forty-three male-adult patients in the group were wearing both Ag/AgCl wet electrode and new dry electrode for sleep monitoring. The wet electrode recording was used as the ... Read more >>

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery)
[2020, 34(7):622-625]

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A mass spectrometry-based proteome map of drug action in lung cancer cell lines.

Benjamin Ruprecht, Julie Di Bernardo, Zhao Wang, Xuan Mo, Oleg Ursu, Matthew Christopher, Rafael B Fernandez, Li Zheng, Brian D Dill, Huijun Wang, Yuting Xu, Andy Liaw, Jonathan D Mortison, Nirodhini Siriwardana, Brian Andresen, Meir Glick, James R Tata, Victoria Kutilek, Ivan Cornella-Taracido, An Chi,

Mass spectrometry-based discovery proteomics is an essential tool for the proximal readout of cellular drug action. Here, we apply a robust proteomic workflow to rapidly profile the proteomes of five lung cancer cell lines in response to more than 50 drugs. Integration of millions of quantitative protein-drug associations substantially improved ... Read more >>

Nat. Chem. Biol. (Nature chemical biology)
[2020, 16(10):1111-1119]

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Roles of gut microbiota and metabolites in a homogalacturonan-type pectic polysaccharide from Ficus pumila Linn. fruits mediated amelioration of obesity.

Jianjun Wu, Yongbin Xu, Juan Su, Bo Zhu, Siqi Wang, Kaohua Liu, Huijun Wang, Songshan Shi, Qiaoyan Zhang, Luping Qin, Shunchun Wang,

In this study, the beneficial effects of a homogalacturonan(HG)-type pectic polysaccharide from Ficus pumila L. fruits (FPLP) in obese mice were investigated. The 17-week FPLP treatment effectively attenuated obesity, as mainly demonstrated by the reductions of body weight, serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels in high-fat ... Read more >>

Carbohydr Polym (Carbohydrate polymers)
[2020, 248:116780]

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Effects of heat shock treatment on the survival rate of Lactobacillus acidophilus after freeze-drying.

Ni Zhen, Xiaoqun Zeng, Huijun Wang, Jing Yu, Daodong Pan, Zhen Wu, Yuxing Guo,

Herein we investigated the effects of heat shock treatment on the resistance of Lactobacillus acidophilus ATCC4356 to freeze-drying and the underlying mechanisms. We assessed the survival rate, cell morphology, enzyme activities, and metabolites in glycometabolism and energy metabolism. Heat shock treated at 45 °C for 30 min has increased the survival rate ... Read more >>

Food Res Int (Food research international (Ottawa, Ont.))
[2020, 136:109507]

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Coexistence of Recurrent Chromosomal Abnormalities and the Philadelphia Chromosome in Acute and Chronic Myeloid Leukemias: Report of Five Cases and Review of Literature

Jinying Gong, Zhenhao Zhang, Wei Zhang, Huijun Wang, Xiaofang Feng, Ji Zhou, Guoqing Zhu,

Abstract Progression of chronic myelogenous leukemia (CML) is frequently accompanied by cytogenetic evolution. Additional genetic abnormalities are seen in 10-20 % of CML cases at the time of diagnosis, and in 60–80 % of cases of advanced disease. Unbalanced chromosomal changes such as an extra copy of the Philadelphia chromosome ... Read more >>

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High-Efficiency [email protected](Fe) Electrochemiluminescence Emitters Coupled with Ti3C2 Nanosheets as a Matrix for a Highly Sensitive Cardiac Troponin I Assay.

Xinya Jiang, Huijun Wang, Yaqin Chai, Wenbing Shi, Ruo Yuan,

Synthesis of a highly efficient electrochemiluminescence (ECL) luminescent material is one of the effective means to improve the sensitivity of the sensor. In this study, an efficient ECL luminescent nanomaterial, carbon nitride nanosheet (CNNS) decorated amino-functional metal-organic frameworks ([email protected](Fe)) were synthesized for sensitive ECL detection of cardiac troponin I (cTn-I). ... Read more >>

Anal. Chem. (Analytical chemistry)
[2020, 92(13):8992-9000]

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Differential Association of Cereal Intake Patterns with Cardiometabolic Risk Factors Among the Adults in China.

Zhihong Wang, Qiumin Huang, Rui Wang, Liusen Wang, Hongru Jiang, Bing Zhang, Huijun Wang, Xiao-Fang Jia, Feifei Huang, Gangqiang Ding,

AbstractObjectivesThis study examined the association between cereal intake patterns and major CM risk factors among Chinese adults.MethodsWe linked the dietary intake and covariates measured in China Health and Nutrition Survey (CHNS) 2011 with CM risk factors measured in CHNS 2015 among 4706 Chinese adults aged ≥18 years. Dietary intake was ... Read more >>

(Current developments in nutrition)
[2020, 4(Suppl 2):1504-1504]

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Correction to: Psychometric properties of the perceived stress scale in a community sample of Chinese.

Feifei Huang, Huijun Wang, Zhihong Wang, Jiguo Zhang, Wenwen Du, Chang Su, Xiaofang Jia, Yifei Ouyang, Yun Wang, Li Li, Hongru Jiang, Bing Zhang,

An amendment to this paper has been published and can be accessed via the original article. ... Read more >>

BMC Psychiatry (BMC psychiatry)
[2020, 20(1):260]

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Arsenic in the Pathway to Cardiovascular Diseases: Arsenic May Mediate Lipid Profile in Adults.

Shufa Du, Liping Liu, Huijun Wang, Bing Zhang, Barry Popkin,

AbstractObjectivesRecent studies indicate arsenic exposure may increase the risk of cardiovascular diseases, but the mechanism of this association is still unknown. This study explores the relationship between urine arsenic levels and serum cholesterol and triglycerides. Our hypothesis is that greater arsenic levels may be associated with dyslipidemia.MethodsWe used data from ... Read more >>

(Current developments in nutrition)
[2020, 4(Suppl 2):1630-1630]

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