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Author Hui Dong

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Potentiometric analysis of sialic acid with a flexible carbon cloth based on boronate affinity and molecularly imprinted polymers.

Yanli Zhou, Huijie Huangfu, Jie Yang, Hui Dong, Lantao Liu, Maotian Xu,

An electrochemical platform was proposed for highly sensitive and selective analysis of sialic acid based on molecularly imprinted polymers (MIPs), which were electropolymerized with the monomer molecules of 3-aminophenylboronic acid (ABA) on a carbon cloth (CC) electrode in the presence of template molecules. The fabricated sensor, named the PABA/CC-based MIP ... Read more >>

Analyst (The Analyst)
[2019, 144(21):6432-6437]

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Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice.

Mao-Yun Yuan, Ze-Ka Chen, Jian Ni, Tian-Xiao Wang, Shi-Yu Jiang, Hui Dong, Wei-Min Qu, Zhi-Li Huang, Rui-Xi Li,

RATIONALE:Major depression is a serious, but common, psychological disorder, which consists of a long-lasting depressive mood, feelings of helplessness, anhedonia, and sleep disturbances. It has been reported that rats with bilateral olfactory bulbectomies (OBXs) exhibit depressive-like behaviors which indicates that the olfactory bulb (OB) plays an important role in the ... Read more >>

Psychopharmacology (Berl.) (Psychopharmacology)
[2020, :]

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The Receptor Kinase BRI1 promotes cell proliferation in Arabidopsis by phosphorylation-mediated inhibition of the growth repressing peptidase DA1

Hui Dong, Caroline Smith, Rachel Prior, Ross Carter, Jack Dumenil, Gerhard Saalbach, Neil McKenzie, Michael Bevan,

Summary Brassinosteroids (BR) have centrally important functions in plant growth by promoting cell proliferation and cell expansion through phosphorylation-mediated regulatory cascades that are initiated by perception of BR by receptor-like kinases of the BRI1 family. These BR-mediated growth responses have been explained by transcriptional controls mediated by phosphorylation of BES1/BZR1 ... Read more >>

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Eimeria tenella Eimeria-specific protein that interacts with apical membrane antigen 1 (EtAMA1) is involved in host cell invasion

Cong Li, Qiping Zhao, Shunhai Zhu, Qingjie Wang, Haixia Wang, Shuilan Yu, Yu Yu, Shashan Liang, Huanzhi Zhao, Bing Huang, Hui Dong, Hongyu Han,

Abstract Background: Avian coccidiosis is a widespread, economically significant disease of poultry, caused by several species of the protozoan parasite Eimeria . Among these species, E. tenella causes hemorrhagic pathologies and high mortality. These parasites have complex and diverse lifestyles that require the invasion of their host cells. This is ... Read more >>

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Isolated Pancreatic Metastasis From Squamous Cell Lung Cancer Mimicking Primary Pancreatic Ductal Adenocarcinoma on FDG PET/CT.

Wei Zhou, Hui Dong, Aisheng Dong,

Isolated pancreatic metastasis from lung cancer is rare. We present a case of isolated pancreatic metastasis from squamous cell lung cancer. The pancreatic tumor showed hypovascularity on enhanced MRI and intense FDG uptake on FDG PET/CT mimicking primary pancreatic ductal adenocarcinoma. This case indicates pancreatic metastasis should be considered as ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2020, 45(5):420-422]

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Molecular Mechanism of Mesenchyme Homeobox 1 in Transforming Growth Factor β1-Induced P311 Gene Transcription in Fibrosis.

Zhiyuan Wei, Chao Han, Haisheng Li, Weifeng He, Junyi Zhou, Hui Dong, Yuzhang Wu, Yi Tian, Gaoxing Luo,

Organ fibrosis is characterized by excessive fibroblast, and extracellular matrix and the molecular basis are not fully elucidated. Recent studies have proven that P311, an 8-kDa conserved protein, could promote various organ fibrosis, such as skin, kidney, liver, and lung, partially through upregulating transforming growth factor β1 (TGF-β1) translation. However, ... Read more >>

Front Mol Biosci (Frontiers in Molecular Biosciences)
[2020, 7:59]

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Molecular characterization of serine/threonine protein phosphatase of Eimeria tenella.

Yu Yu, Qiping Zhao, Shunhai Zhu, Hui Dong, Bing Huang, Shanshan Liang, Qingjie Wang, Haixia Wang, Shuilan Yu, Hongyu Han,

Avian coccidiosis is a widespread and economically significant poultry disease caused by several Eimeria species, including Eimeria tenella. Previously, E. tenella serine/threonine protein phosphatase (EtSTP) was found to be differentially expressed in drug-sensitive (DS) and drug-resistant strains using RNA-seq. In the present study, we found that transcription and translation levels of ... Read more >>

J. Eukaryot. Microbiol. (The Journal of eukaryotic microbiology)
[2020, :]

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Proteomics Profiling Reveals Insulin-Like Growth Factor 1, Collagen Type VI α-2 Chain, and Fermitin Family Homolog 3 as Potential Biomarkers of Plaque Erosion in ST-Segment Elevated Myocardial Infarction.

Jinxin Liu, Shanjie Wang, Jingbo Hou, Hengxuan Cai, Weili Pan, Haimeng Dong, Rong Sun, Hui Dong, Shaohong Fang, Bo Yu,

BACKGROUND:Plaque erosion (PE) has been considered a secondary pathogenesis of ST-segment elevated myocardial infarction (STEMI) following plaque rupture (PR). Previous studies demonstrated that they had different demographic and histology characteristics and need different treatment strategy. But there are few non-invasive plasma biomarkers for distinguishing them. The present study aimed to ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(6):985-993]

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18F-FDG PET/CT and 68Ga-DOTATOC PET/CT in Diffuse Pancreatic Neuroendocrine Tumor.

Xia Ji, Aisheng Dong, Qi He, Hui Dong, Changjing Zuo,

We present 2 cases of pancreatic neuroendocrine tumor with diffuse involvement of the entire pancreas. One case with G2 pancreatic neuroendocrine tumor showed nearly normal pancreatic shape and signal intensity on MRI, normal pancreatic FDG uptake, and diffuse pancreatic Ga-DOTATOC uptake. The other case with G3 pancreatic neuroendocrine tumor showed ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2020, 45(5):e245-e248]

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Relationship between elevated plasma ceramides and plaque rupture in patients with ST-segment elevation myocardial infarction.

Weili Pan, Meng Sun, Jianjun Wu, Hui Dong, Jinxin Liu, Rui Gao, Shaohong Fang, Lei Xing, Sining Hu, Bo Yu,

BACKGROUND AND AIMS:Ceramides (Cer) are an atherogenic substance. However, the associations between specific plasma Cer levels and culprit plaque morphology in ST-segment elevation myocardial infarction (STEMI) patients are unclear. METHODS:The study consisted of two parallel cohorts. 100 consecutive patients with STEMI were screened as discovery cohort. In the validation cohort, ... Read more >>

Atherosclerosis (Atherosclerosis)
[2020, 302:8-14]

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Enhancing the magnetic relaxivity of MRI contrast agents via the localized superacid microenvironment of graphene quantum dots.

Yongqiang Li, Hui Dong, Quan Tao, Caichao Ye, Mengmeng Yu, Jipeng Li, Huifang Zhou, Siwei Yang, Guqiao Ding, Xiaoming Xie,

The design of contrast agents (CAs) with high magnetic relaxivities is a key issue in the field of magnetic resonance imaging (MRI). The traditional strategy employed is aimed at optimizing the structural design of the magnetic atoms in the CA. However, it is difficult to obtain an agent with magnetic ... Read more >>

Biomaterials (Biomaterials)
[2020, 250:120056]

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A case of adult-onset neuronal intranuclear inclusion disease without abnormal high-intensity signal in the corticomedullary junction in diffusion-weighted imaging.

Hui Dong, Guang Ji, Peipei Liu, Yuehong Li, Yun Tian, Lu Shen, Yaling Liu, Xueqin Song,

Neurol. Sci. (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2020, :]

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An integrated platform for the capture of circulating tumor cells and in situ SERS profiling of membrane proteins through rational spatial organization of multi-functional cyclic RGD nanopatterns.

Hui Dong, Dazhi Yao, Qi Zhou, Limin Zhang, Yang Tian,

It is significant to in situ monitor membrane proteins at the single-cell level for understanding the cell function. Herein, an integrated platform was designed and constructed for highly efficient cell capture and in situ sensitive SERS determination of HER2 activity in cells through rational spatial organization of multi-functional cyclic RGD ... Read more >>

Chem. Commun. (Camb.) (Chemical communications (Cambridge, England))
[2019, 55(12):1730-1733]

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Effect of regular intravenous immunoglobulin therapy on prognosis of severe pneumonia in patients with COVID-19.

Yun Xie, Song Cao, Hui Dong, Qingyun Li, Erzhen Chen, Wenkai Zhang, Luyu Yang, Shouzhi Fu, Ruilan Wang,

J. Infect. (The Journal of infection)
[2020, :]

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Comprehensive Analysis of the Genetic and Epigenetic Mechanisms of Osteoporosis and Bone Mineral Density.

Hui Dong, Wenyang Zhou, Pingping Wang, Enjun Zuo, Xiaoxia Ying, Songling Chai, Tao Fei, Laidi Jin, Chen Chen, Guowu Ma, Huiying Liu,

Osteoporosis is a skeletal disorder characterized by a systemic impairment of bone mineral density (BMD). Genome-wide association studies (GWAS) have identified hundreds of susceptibility loci for osteoporosis and BMD. However, the vast majority of susceptibility loci are located in non-coding regions of the genome and provide limited information about the ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2020, 8:194]

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The Role of HBx Gene Mutations in PLA 2R Positive Hepatitis-B-associated Membranous Nephropathy.

Hui Dong, Yan Xu, Ting Xu, Jing Yi Sun, Quan Dong Bu, Yan Fei Wang, Lin Che, Long Zhao, Wei Jiang,

Biomed. Environ. Sci. (Biomedical and environmental sciences : BES)
[2020, 33(4):269-272]

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Plasma Ceramides in Relation to Coronary Plaque Characterization Determined by Optical Coherence Tomography.

Weili Pan, Hui Dong, Rong Sun, Linlin Zhao, Meng Sun, Longyan Li, Xianghao Yu, Jinxin Liu, Jianjun Wu, Fan Yang, Bo Yu,

Plasma ceramides (Cer), a subset of bioactive lipids, have mechanistic links to development of atherosclerosis and are related to major adverse cardiovascular events (MACEs). Previous researches have demonstrated vulnerable plaques contribute to acute cardiovascular events and poor prognosis. This study aimed to explore the associations between Cer and culprit plaque ... Read more >>

J Cardiovasc Transl Res (Journal of cardiovascular translational research)
[2020, :]

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New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo

Fangmiao Sun, Jingheng Zhou, Bing Dai, Tongrui Qian, Jianzhi Zeng, Xuelin Li, Yizhou Zhuo, Yajun Zhang, Ke Tan, Jiesi Feng, Hui Dong, Cheng Qian, Dayu Lin, Guohong Cui, Yulong Li,

The monoamine neuromodulator dopamine (DA) plays a critical role in the brain, and the ability to directly measure dopaminergic activity is essential for understanding its physiological functions. We therefore developed the first red fluorescent GPCR-activation–based DA (GRAB DA ) sensors and optimized versions of green fluorescent GRAB DA sensors following ... Read more >>

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An Electrochemophysiological Microarray for Real-Time Monitoring and Quantification of Multiple Ions in the Brain of a Freely Moving Rat.

Fan Zhao, Yuandong Liu, Hui Dong, Shiqing Feng, Guoyue Shi, Longnian Lin, Yang Tian,

Herein, we present an electrochemophysiological microarray (ECPM) for real-time mapping and simultaneous quantification of chemical signals for multiple ions in the deep brain of a freely moving rat, in which microelectrode arrays were developed for direct determination of multiple ions using open-circuit potentiometry. Specific recognition ionophores were synthesized and optimized ... Read more >>

Angew. Chem. Int. Ed. Engl. (Angewandte Chemie (International ed. in English))
[2020, :]

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Protective effects of new aryl sulfone derivatives against radiation-induced hematopoietic injury.

Jian Cao, Hongyan Li, Renbin Yuan, Yinping Dong, Jing Wu, Meifang Wang, Deguan Li, Hongqi Tian, Hui Dong,

The hematopoietic system is sensitive to radiation. In this research, new aryl sulfone derivatives (XH-201 and XH-202) containing a nitrogen heterocycle were designed and synthesized and their radio-protective efficacies with regard to the hematopoietic system were evaluated. XH-201 administration significantly increased the survival rate of mice after 8.0 Gy total body ... Read more >>

J. Radiat. Res. (Journal of radiation research)
[2020, 61(3):388-398]

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CT scores predict mortality in 2019-nCoV pneumonia

Yun Xie, Luyu Yang, Hui Dong, Hu Peng, Yuetian Yu, Guowei Tu, Qingyun Li, Shouzhi Fu, Ruilan Wang,

Abstract Background: While 2019-nCoV nucleic acid swab tests has high false positives rate, How to diagnose 2019-nCoV pneumonia and predict prognosis by CT is very important. Methods: In this retrospective single-center study, we consecutively included suspected 2019-nCoV pneumonia critical cases in the intensive care unit of Wuhan third hospital ... Read more >>

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Correlation Analysis Between Disease Severity and Inflammation-related Parameters in Patients with COVID-19 Pneumonia

Jing Gong, Hui Dong, Song Qing Xia, Yi Zhao Huang, Dingkun Wang, Yan Zhao, Wenhua Liu, Shenghao Tu, Mingmin Zhang, Qi Wang, Fuer Lu,

Aim: The new coronavirus pneumonia (COVID-19) outbreaking at the end of 2019 is highly contagious. Crude mortality rate reached 49% in critical patients. Inflammation matters on disease progression. This study analyzed blood inflammation indicators among mild, severe and critical patients, helping to identify severe or critical patients early. Methods: In ... Read more >>

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Polarizing Graphene Quantum Dots toward Long-Acting Intracellular Reactive Oxygen Species Evaluation and Tumor Detection.

Anli Xu, Peng He, Caichao Ye, Zhiduo Liu, Bingli Gu, Bo Gao, Yongqiang Li, Hui Dong, Da Chen, Gang Wang, Siwei Yang, Guqiao Ding,

The evaluation of intracellular reactive oxygen species (ROS) would greatly deepen the understanding of cell metabolism/proliferation and tumor detection. However, current long-acting level tracking techniques for intracellular ROS remain unsuited to practical applications. To solve this problem, we synthesized cyclotriphosphazene-doped graphene quantum dots (C-GQDs) whose quantum yield is highly sensitive ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(9):10781-10790]

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Optimal clutch size for quality control of bisexual and Wolbachia-infected thelytokous lines of Trichogramma dendrolimi Matsumura (Hymenoptera: Trichogrammatidae) mass reared on eggs of a substitutive host, Antheraea pernyi Guérin-Méneville (Lepidoptera: Saturniidae).

Jin-Cheng Zhou, Quan-Quan Liu, Qian-Ru Wang, Su-Fang Ning, Wu-Nan Che, Hui Dong,

BACKGROUND:Trichogramma dendrolimi has been widely used in augmentative biocontrol of lepidopteran pests in China. In mass production of T. dendrolimi using Antheraea pernyi eggs as substitutive hosts, which are large in size, as clutch size is a parameter of importance to produce high quality parasitoids. Here, we aimed to determine ... Read more >>

Pest Manag. Sci. (Pest management science)
[2020, :]

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Silencing of long noncoding RNA LEF1-AS1 prevents the progression of hepatocellular carcinoma via the crosstalk with microRNA-136-5p/WNK1.

Hui Dong, Peng Jian, Mengchu Yu, Lixin Wang,

Long noncoding RNAs (lncRNAs) have been recognized as cancer-associated biological molecules, favoring hepatocellular carcinoma (HCC) progression. This study was conducted to elucidate the effects lncRNA lymphoid enhancer-binding Factor 1 antisense RNA (LEF1-AS1) on the pathological development of HCC, along with the crosstalk involving microRNA-136-5p (miR-136-5p) and with-no-K (lysine) kinase 1 ... Read more >>

J. Cell. Physiol. (Journal of cellular physiology)
[2020, :]

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