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Author Huawei Lin

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Effects of Docetaxel Combined with Icotinib on Serum Tumor Markers and Quality of Life of Patients with Advanced Non-Small Cell Lung Cancer.

Huawei Lin, Jing Chang, Jun Li,

<h4>Background</h4>To investigate the effects of docetaxel combined with icotinib on tumor markers in serum and quality of life of patients with advanced non-small cell lung cancer (NSCLC).<h4>Methods</h4>Overall, 121 patients with advanced NSCLC, admitted to the Third Affiliated Hospital of Shandong First Medical University, China from 2017-2018 were selected as subjects. ... Read more >>

Iran J Public Health (Iranian journal of public health)
[2020, 49(10):1885-1893]

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Longitudinal tracing of neurochemical metabolic disorders in working memory neural circuit and optogenetics modulation in rats with vascular cognitive impairment.

Huawei Lin, Tingting Jin, Lewen Chen, Yaling Dai, Weiwei Jia, Xiaojun He, Minguang Yang, Jianhong Li, Shengxiang Liang, Jinsong Wu, Jia Huang, Lidian Chen, Weilin Liu, Jing Tao,

Chronic cerebral ischemia leads to vascular cognitive impairment (VCI) that exacerbates along with ischemia time and eventually develops into dementia. Recent advances in molecular neuroimaging contribute to understand its pathological characteristics. We previously traced the anisotropic diffusion of water molecules suggests that chronic cerebral ischemia leads to irreversible progressive damage ... Read more >>

Brain Res Bull (Brain research bulletin)
[2021, 170:174-186]

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Longitudinal tracing of neurochemical metabolic disorders in working memory neural circuit and optogenetics modulation in rats with vascular cognitive impairment

Huawei Lin, Tingting Jin, Lewen Chen, Yaling Dai, Weiwei Jia, Xiaojun He, Minguang Yang, Jianhong Li, Shengxiang Liang, Jinsong Wu, Jia Huang, Lidian Chen, Weilin Liu, Jing Tao,

<h4>Objective: </h4> Chronic cerebral ischemia leads to vascular cognitive impairment (VCI) that exacerbates along with ischemia time and eventually develops into dementia. Recent advances in molecular neuroimaging contribute to understand its pathological characteristics. We previously traced the anisotropic diffusion of water molecules suggests that chronic cerebral ischemia leads to irreversible ... Read more >>

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Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke.

Shenghang Zhang, Tingting Jin, Lulu Wang, Weilin Liu, Yuhao Zhang, Yi Zheng, Yunjiao Lin, Minguang Yang, Xiaojun He, Huawei Lin, Lidian Chen, Jing Tao,

Background: Evidences indicate that exosomes-mediated delivery of microRNAs (miRNAs or miRs) is involved in the neurogenesis of stroke. This study was to investigate the role of exosomal miRNAs in non-drug therapy of electro-acupuncture (EA) regulating endogenous neural stem cells for stroke recovery. Methods: The model of focal cerebral ischemia and ... Read more >>

Front Cell Neurosci (Frontiers in cellular neuroscience)
[2020, 14:223]

Cited: 2 times

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Neurogranin as a cognitive biomarker in cerebrospinal fluid and blood exosomes for Alzheimer's disease and mild cognitive impairment.

Weilin Liu, Huawei Lin, Xiaojun He, Lewen Chen, Yaling Dai, Weiwei Jia, Xiehua Xue, Jing Tao, Lidian Chen,

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with clinical, biological, and pathological features occurring along a continuum from normal to end-stage disease. Currently, the diagnosis of AD depends on clinical assessments and post-mortem neuropathology, which is unbenefited early diagnosis and progressive monitoring. In recent years, clinical studies have reported ... Read more >>

Transl Psychiatry (Translational psychiatry)
[2020, 10(1):125]

Cited: 3 times

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Shanghai cognitive intervention of mild cognitive impairment for delaying progress with longitudinal evaluation-a prospective, randomized controlled study (SIMPLE): rationale, design, and methodology.

Yiqi Lin, Binyin Li, Huidong Tang, Qun Xu, Yuncheng Wu, Qi Cheng, Chunbo Li, Shifu Xiao, Lu Shen, Weiguo Tang, Hui Yu, Naying He, Huawei Lin, Fuhua Yan, Wenwei Cao, Shilin Yang, Ye Liu, Wei Zhao, Dong Lu, Bin Jiao, Xuewen Xiao, Lin Zhou, Shengdi Chen,

<h4>Background</h4>Mild cognitive impairment is an early stage of Alzheimer's disease. Increasing evidence has indicated that cognitive training could improve cognitive abilities of MCI patients in multiple cognitive domains, making it a promising therapeutic approach for MCI. However, the effect of long-time training has not been widely explored. It is also ... Read more >>

BMC Neurol (BMC neurology)
[2018, 18(1):103]

Cited: 3 times

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[Treatment of autotransplantation of NT-3 gene modified OECs and NSCs complex adhering to scaffold on spontaneous cerebral hemorrhage].

Chunjuan Wang, Jinshan Yang, Huawei Lin, Peicai Fu, Shougang Guo, Ronghua Tang,

<h4>Objective</h4>To explore the effects of autotransplantation of NT-3 gene modified olfactory ensheathing cell (OEC) and neural stem cell (NSC) complex adhering to collagen protein-heparin sulfate scaffold on motor function of rats with cerebral hemorrhage.<h4>Methods</h4>The cerebral hemorrhage model was established with caudate nucleus bleeding in Wistar rats. The animals were randomly ... Read more >>

Zhonghua Yi Xue Za Zhi (Zhonghua yi xue za zhi)
[2014, 94(19):1483-1487]

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Arterial stiffness and asymptomatic intracranial large arterial stenosis and calcification in hypertensive chinese.

Jin Zhang, Yan Li, Yan Wang, Wenquan Niu, Yi Zhang, Pingjin Gao, Liyun Zhang, Huawei Lin, Kemin Chen, Dingliang Zhu,

<h4>Background</h4>Intracranial large artery disease (ICLAD), such as stenosis and calcification, is common in Chinese patients with stroke. However, little is known about ICLAD and its association with large arterial stiffness in hypertensive patients.<h4>Methods</h4>We recruited 270 (mean age 61.0 years, 45.6% male) untreated hypertensive patients without stroke from a community in ... Read more >>

Am J Hypertens (American journal of hypertension)
[2011, 24(3):304-309]

Cited: 27 times

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