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Femtosecond laser semi-assisted Descemet stripping endothelial keratoplasty: 2-year outcomes of endothelial cell loss and graft survival.

Ting Wang, Peiyan Shi, Fengjie Li, Hua Gao, Suxia Li, Tong Liu, Weiyun Shi,

<h4>Purpose</h4>To assess 2-year endothelial cell loss and graft survival after femtosecond laser semi-assisted Descemet stripping endothelial keratoplasty (FLS-DSEK).<h4>Methods</h4>In this prospective and noncomparative study carried out at Eye Hospital of Shandong First Medical University, 85 eyes (84 patients) with endothelial dysfunction receiving FLS-DSEK (n=62, 75.9%) or FLS-DSEK combined with phacoemulsification cataract ... Read more >>

Graefes Arch Clin Exp Ophthalmol (Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie)
[2021, :]

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0.75 Gbit/s high-speed classical key distribution with mode-shift keying chaos synchronization of Fabry-Perot lasers.

Hua Gao, Anbang Wang, Longsheng Wang, Zhiwei Jia, Yuanyuan Guo, Zhensen Gao, Lianshan Yan, Yuwen Qin, Yuncai Wang,

High-speed physical key distribution is diligently pursued for secure communication. In this paper, we propose and experimentally demonstrate a scheme of high-speed key distribution using mode-shift keying chaos synchronization between two multi-longitudinal-mode Fabry-Perot lasers commonly driven by a super-luminescent diode. Legitimate users dynamically select one of the longitudinal modes according ... Read more >>

Light Sci Appl (Light, science & applications)
[2021, 10(1):172]

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Evolution of Acinetobacter baumannii in Clinical Bacteremia Patients.

Henan Li, Jiangang Zhang, Zhiren Wang, Yuyao Yin, Hua Gao, Ruobing Wang, Longyang Jin, Qi Wang, Chunjiang Zhao, Zhanwei Wang, Hui Wang,

<h4>Introduction</h4>Colonization of the respiratory tract by <i>Acinetobacter baumannii</i> has been established as an independent risk factor for bacteremia. However, within-host evolution of <i>A. baumannii</i> in bacteremia has not been extensively investigated.<h4>Methods</h4>We performed whole-genome sequencing to discover the evolutionary characteristics that accompany the transition from respiratory tract carriage to bloodstream infection ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2021, 14:3553-3562]

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A New Accurate, Simple and Less Radiation Exposure Device for Distal Locking of Femoral Intramedullary Nails.

Hua Gao, Zhenyu Liu, Gang Wang, Baojun Wang,

<h4>Background</h4>Due to the metal elasticity of intramedullary nails (IMs) and irregularities of the long bone marrow cavity and other reasons, one of the greatest challenges for surgeons is to position the distal locking screw. Therefore, a novel laser guiding navigation device was designed for the distal locking of femoral IMs. ... Read more >>

Int J Gen Med (International journal of general medicine)
[2021, 14:4145-4153]

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Expression and Significance of miR-654-3p/ARL4C in Patients with Glioma

Hua Gao, Yang Zhongjin, Li Zhenye, Li Zhenzong,

<h4>Background: </h4> ADP-ribosylation-like factor4C (ARL4C) is overexpressed in several cancer tissues and is involved in cancer development. Increasing evidence reveals that aberrant microRNAs (miRNAs) expression play a crucial role in the tumorigenesis of cancers. Nevertheless, the exact mechanism that regulates ARL4C expression in glioma has not been fully elucidated. The ... Read more >>

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Limitations of the transmitted photonic spin Hall effect through layered structure

Chong Miao, Dongxue Wang, Eric Herrmann, Zhiyuan Zheng, Haochong Huang, Hua Gao,

In this paper, we show theoretically that the spin-dependent transverse shift of the transmitted photonic spin Hall effect (SHE) through layered structure cannot exceed half of the incident beam waist. Three conditions for obtaining the upper limit of the transmitted SHE are clarified in detail. In addition, different from the ... Read more >>

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Effect of Pramipexole on Inflammatory Response in Central Nervous System of Parkinson's Disease Rat Model.

Sen Jiang, Hua Gao, Yuxuan Yong, Huaxiong Zhang, Peishan Li, Yanxia Li, Qin Luo, Xinling Yang,

<h4>Background</h4>Pramipexole is the dopamine receptor agonist commonly used for treatment of PD, the effect of which on immunity played an important role in pathological process is also deserved to be further studied.<h4>Aim of study</h4>We observed the effect of pramipexole on behavior and central nervous system (CNS) inflammatory cytokines of Parkinson's ... Read more >>

Arch Med Res (Archives of medical research)
[2021, :]

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Functional specificity, diversity, and redundancy of Arabidopsis JAZ family repressors in jasmonate and COI1-regulated growth, development, and defense.

Bei Liu, Kyungyong Seong, Shihai Pang, Junqiao Song, Hua Gao, Cuili Wang, Jiaqi Zhai, Yue Zhang, Shang Gao, Xuedong Li, Tiancong Qi, Susheng Song,

In response to jasmonates (JAs), the JA receptor Coronatine Insensitive 1 (COI1) recruits JA-zinc-finger inflorescence meristem (ZIM)-domain (JAZ) family repressors for destruction to regulate plant growth, development, and defense. As Arabidopsis encodes 13 JAZ repressors, their functional specificity, diversity, and redundancy in JA/COI1-mediated responses remain unclear. We generated a broad range ... Read more >>

New Phytol (The New phytologist)
[2021, 231(4):1525-1545]

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A semiconductor/molecular catalyst hybrid photoanode with FeOOH as an electron transfer relay.

Zhifeng Zhao, Guoquan Liu, Yong Zhu, Hua Gao, Fei Li,

A Fe<sub>2</sub> O<sub>3</sub> /FeOOH/poly-Ru(bda)(vpy) (bda = 2,2'-bipyridine-6,6'-dicarboxylate,vpy = 4-vinylpyridine) photoanode has been fabricated by electropolymerization of molecular Ru(bda)(vpy) catalyst on FeOOH modified Fe<sub>2</sub> O<sub>3</sub> , in which a thin layer of FeOOH replicates the role of tyrosine residue in PSII as an efficient electron transfer mediator. The ternary hybrid photoanode ... Read more >>

Chem Asian J (Chemistry, an Asian journal)
[2021, 16(13):1745-1749]

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Comparison of complications and visual outcomes between big-bubble deep anterior lamellar keratoplasty and penetrating keratoplasty for fungal keratitis.

Xiunian Chen, Xiaofeng Li, Xiaoyu Zhang, Xiaoting Guo, Xiaolin Qi, Suxia Li, Weiyun Shi, Hua Gao,

<h4>Background</h4>To compare the postoperative complications and visual outcomes of big-bubble deep anterior lamellar keratoplasty (BB-DALK) and penetrating keratoplasty (PK) for fungal keratitis (FK).<h4>Methods</h4>This retrospective study included 94 cases of BB-DALK for FK and 161 cases of PK for FK from a tertiary ophthalmology care centre.<h4>Results</h4>The most common FK pathogens were ... Read more >>

Clin Exp Ophthalmol (Clinical & experimental ophthalmology)
[2021, 49(6):550-559]

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Genotype Profile of Global EYS-Associated Inherited Retinal Dystrophy and Clinical Findings in a Large Chinese Cohort.

Ke Xu, De-Fu Chen, Haoyu Chang, Ren-Juan Shen, Hua Gao, Xiao-Fang Wang, Zhuo-Kun Feng, Xiaohui Zhang, Yue Xie, Yang Li, Zi-Bing Jin,

<h4>Purpose</h4>The aim of this study was to probe the global profile of the EYS-associated genotype-phenotype trait in the worldwide reported IRD cases and to build a model for predicting disease progression as a reference for clinical consultation.<h4>Methods</h4>This retrospective study of 420 well-documented IRD cases with mutations in the <i>EYS</i> gene ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2021, 9:634220]

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Overexpression of the Apple (Malus × domestica) MdERF100 in Arabidopsis Increases Resistance to Powdery Mildew.

Yiping Zhang, Li Zhang, Hai Ma, Yichu Zhang, Xiuming Zhang, Miaomiao Ji, Steve van Nocker, Bilal Ahmad, Zhengyang Zhao, Xiping Wang, Hua Gao,

APETALA2/ETHYLENE RESPONSIVE FACTOR (AP2/ERF) transcription factors play important roles in plant development and stress response. Although <i>AP2/ERF</i> genes have been extensively investigated in model plants such as <i>Arabidopsis thaliana</i>, little is known about their role in biotic stress response in perennial fruit tree crops such as apple (<i>Malus × domestica</i>). ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2021, 22(11):]

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Identification of a Novel Hybrid Plasmid Encoding KPC-2 and Virulence Factors in Klebsiella pneumoniae Sequence Type 11.

Longyang Jin, Ruobing Wang, Hua Gao, Qi Wang, Hui Wang,

Recent emergence of carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) coharboring <i>bla</i> <sub>KPC-2</sub> and pLVPK-like virulence plasmids represented a novel clinical challenge. In the present study, we characterized a <i>bla</i> <sub>KPC-2</sub> and virulence hybrid plasmid, designated pCRHV-C2244, from a clinical ST11-K64 CRKP strain. pCRHV-C2244 was non-self-transmissible due to incomplete conjugative elements but mobilizable ... Read more >>

Antimicrob Agents Chemother (Antimicrobial agents and chemotherapy)
[2021, 65(6):]

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Endocrinological and metabolic characteristics in patients who are non-obese and have polycystic ovary syndrome and different types of a family history of type 2 diabetes mellitus.

Yuan Wang, Hua Gao, Wen Di, Zhuowei Gu,

<h4>Objective</h4>We aimed to investigate whether patients with polycystic ovary syndrome (PCOS) and a family history (FH) of type 2 diabetes mellitus (T2DM) are at increased risk of endocrinological and metabolic abnormalities, and whether this risk differs between first-degree and second-degree relatives, and between maternal and paternal transmission.<h4>Methods</h4>A total of 680 ... Read more >>

J Int Med Res (The Journal of international medical research)
[2021, 49(5):3000605211016672]

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Different Indicators of Adiposity and Fat Distribution and Cardiometabolic Risk Factors in Patients with Type 2 Diabetes.

Li Ding, Yuxin Fan, Jing He, Ruodan Wang, Qing He, Jingqiu Cui, Zhongshu Ma, Fangqiu Zheng, Hua Gao, Chenlin Dai, Hongyan Wei, Jun Li, Yuming Cao, Gang Hu, Ming Liu,

<h4>Objective</h4>This study aimed to evaluate the effect of adiposity and fat distribution on the odds of elevated cardiovascular risk factors among adults with type 2 diabetes mellitus.<h4>Methods</h4>The present cross-sectional study included 2,427 adults with type 2 diabetes mellitus. Body fat was assessed by dual-energy x-ray absorptiometry. Multivariate-adjusted logistic regression was ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2021, 29(5):837-845]

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Pramipexole attenuates 6-OHDA-induced Parkinson's disease by mediating the Nurr1/NF-κB pathway.

Hua Gao, Dan Wang, Yu-Ling Wang, Jie-Ping Mao, Sen Jiang, Xin-Ling Yang,

Neuroinflammation is the key factor associated with the progression of Parkinson's disease (PD). Pramipexole (PPX) has anti-inflammatory and antioxidant properties. This study explored the effects of PPX on PD and its related mechanisms. A PD rat model was established using 6-hydroxydopamine (6-OHDA). Thirty rats were divided into the following three ... Read more >>

Mol Biol Rep (Molecular biology reports)
[2021, 48(4):3079-3087]

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Postoperative corneal biomechanics and influencing factors during femtosecond-assisted laser in situ keratomileusis (FS-LASIK) and laser-assisted subepithelial keratomileusis (LASEK) for high myopia.

Mingna Liu, Weiyun Shi, Xin Liu, Na Li, Tong Chen, Hua Gao,

The purpose of this study is to compare the postoperative corneal biomechanics and assess the influence factors after femtosecond-assisted laser in situ keratomileusis (FS-LASIK) and laser-assisted subepithelial keratomileusis (LASEK) for high myopia. In this retrospective study, patients who completed 1-year follow-up were included. The corneal biomechanical parameters, including deformation amplitude ... Read more >>

Lasers Med Sci (Lasers in medical science)
[2021, 36(8):1709-1717]

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Teprotumumab: The Dawn of Therapies in Moderate-to-Severe Thyroid-Associated Ophthalmopathy.

Yizhi Ding, Shaoqin Yang, Hua Gao,

Thyroid-associated ophthalmopathy (TAO) is a potentially sight-threatening ocular disease. About 3-5% of patients with TAO have severe disease with intense pain, inflammation, and sight-threatening corneal ulceration or compressive optic neuropathy. The current treatments of TAO are often suboptimal, mainly because the existing therapies do not target the pathogenesis of the ... Read more >>

Horm Metab Res (Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme)
[2021, 53(4):211-218]

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NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.

Hua Gao, Dan Wang, Sen Jiang, Jieping Mao, Xinling Yang,

Parkinson's disease (PD) is one of the most disabling diseases of the central nervous system, seriously affecting health and quality of life for the elderly. The present study aimed to explore the effects of nuclear receptor subfamily 4 group A member 2 (Nurr1) and nuclear factor‑κB (NF‑κB) on the progression of Parkinson's disease ... Read more >>

Mol Med Rep (Molecular medicine reports)
[2021, 23(6):]

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Genome-wide identification and expression analysis of the B-box transcription factor gene family in grapevine (Vitis vinifera L.).

Xiuming Zhang, Li Zhang, Miaomiao Ji, Yifei Wu, Songlin Zhang, Yanxun Zhu, Jin Yao, Zhi Li, Hua Gao, Xiping Wang,

<h4>Background</h4>B-box (BBX) zinc-finger transcription factors play important roles in plant growth, development, and stress response. Although these proteins have been studied in model plants such as Arabidopsis thaliana or Oryza sativa, little is known about the evolutionary history or expression patterns of BBX proteins in grapevine (Vitis vinifera L.).<h4>Results</h4>We identified ... Read more >>

BMC Genomics (BMC genomics)
[2021, 22(1):221]

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Natural products as pharmacological modulators of mitochondrial dysfunctions for the treatments of Alzheimer's disease: A comprehensive review.

Xin Jin, Jia-Ling Guo, Lin Wang, Xin Zhong, Wei-Fan Yao, Hua Gao, Ming-Yan Liu,

Alzheimer's disease (AD) is the most common progressive neurodegenerative disorder characterized by neuronal loss and cognitive impairment that harshly affect the elderly individuals. Currently, the available anti-AD pharmacological approaches are purely symptomatic to alleviate AD symptoms, and the curative effects of novel anti-AD drugs focused on Aβ target are disappointing. ... Read more >>

Eur J Med Chem (European journal of medicinal chemistry)
[2021, 218:113401]

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Control of seed size by jasmonate.

Shuai Hu, Haitao Yang, Hua Gao, Jianbin Yan, Daoxin Xie,

Seed size, an important agronomic trait determining crop yield, is regulated by multiple plant hormones. Jasmonate (JA) is a key phytohormone required for various plant defenses and diverse developmental processes. Here, we defined an essential role for JA in control of seed size. Through comprehensive analysis of genetic mutants in ... Read more >>

Sci China Life Sci (Science China. Life sciences)
[2021, 64(8):1215-1226]

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Comparative Study of Volatile Compounds and Expression of Related Genes in Fruit from Two Apple Cultivars during Different Developmental Stages.

Shuaishuai Feng, Chengtai Yan, Tianhao Zhang, Miaomiao Ji, Ru Tao, Hua Gao,

Aromatic volatile compounds are important contributors to fruit quality that vary among different cultivars. Herein, headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry was used to determine changes in volatile compounds and related gene expression patterns in "Ruixue" and "Fuji" apples (<i>Malus domestica</i> Borkh.) during fruit development and maturation. Volatile ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2021, 26(6):]

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Kilometers Long Graphene-Coated Optical Fibers for Fast Thermal Sensing.

Yiyong Guo, Bing Han, Junting Du, Shanshan Cao, Hua Gao, Ning An, Yiwei Li, Shujie An, Zengling Ran, Yue Lin, Wencai Ren, Yunjiang Rao, Baicheng Yao,

The combination of optical fiber with graphene has greatly expanded the application regimes of fiber optics, from dynamic optical control and ultrafast pulse generation to high precision sensing. However, limited by fabrication, previous graphene-fiber samples are typically limited in the micrometer to centimeter scale, which cannot take the inherent advantage ... Read more >>

Research (Wash D C) (Research (Washington, D.C.))
[2021, 2021:5612850]

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Association of neonatal blood levels of brain-derived neurotrophic factor with development of autism spectrum disorder: a systematic review and meta-analysis.

Ya-Kun Liu, Hua Gao, Shao-Bin Jin, Wen-Jun Tu, Ya-Jun Chen,

<h4>Background</h4>Our goal was to evaluate the association between neonatal blood brain-derived neurotrophic factor (BDNF) level and autism spectrum disorder (ASD) diagnosis later in life.<h4>Methods</h4>MEDLINE and Web of Science databases were searched from inception until September 16, 2020. Reference lists of all relevant articles also were reviewed. Mean blood BDNF concentrations, ... Read more >>

World J Pediatr (World journal of pediatrics : WJP)
[2021, 17(2):164-170]

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