Full Text Journal Articles by
Author Hongli He

Advertisement

Find full text journal articles






The Cardiac Injury in Hospitalized Patients with Severe COVID-19 in Wuhan, China

Sen Lu, Hongli He, Rong an Liu, Yaqiu Wu, Lei Deng, Pin Wang, Weiwei Huang, Yong Peng, Hongwen Xiao, Gang Li, Xiaobo Huang,

Abstract Background: The Coronavirus disease 2019 (COVID-19) has caused a global pandemic since December 2019, while the date on the relationship between cardiac injury and mortality in patients with COVID-19 is limited. Methods: All consecutive lab-confirmed critically ill COVID-19 patients in intensive care unit of Wuhan Red Cross Hospital from ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



How to transform a general hospital into an "infectious disease hospital" during the epidemic of COVID-19.

Hongli He, Caiying Hu, Nian Xiong, Cheng Liu, Xiaobo Huang,

Crit Care (Critical care (London, England))
[2020, 24(1):145]

Cited: 0 times

View full text PDF listing >>



Advertisement

Elastin-like polypeptide and γ-zein fusions significantly increase recombinant protein accumulation in soybean seeds

Jing Yang, Lu Niu, Hongli He, Yunqing Cheng, Xiaofang Zhong, Qianqian Zhao, Guojie Xing, Jianfeng Liu, Xiangdong Yang,

Abstract Background Soybean seeds are an ideal host for the production of recombinant proteins because of their high content of proteins, long-term stability of seed proteins under ambient conditions, and easy establishment of efficient purification protocols. Results In this study, a polypeptide fusion strategy was applied to explore the capacity ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Therapeutic potential of mesenchymal stem/stromal cell-derived secretome and vesicles for lung injury and disease.

Airan Liu, Xiwen Zhang, Hongli He, Li Zhou, Yoshifumi Naito, Shinji Sugita, Jae-Woo Lee,

Introduction: The acute respiratory distress syndrome (ARDS) is a devastating clinical condition common in patients with respiratory failure. Based largely on numerous preclinical studies and recent Phase I/II clinical trials, administration of stem cells, specifically mesenchymal stem or stromal cells (MSC), as a therapeutic for acute lung injury (ALI) holds ... Read more >>

Expert Opin Biol Ther (Expert opinion on biological therapy)
[2020, 20(2):125-140]

Cited: 1 time

View full text PDF listing >>



Whole-Genome Re-Sequencing of Corylus heterophylla Blank-Nut Mutants Reveals Sequence Variations in Genes Associated With Embryo Abortion.

Yunqing Cheng, Siqi Jiang, Xingzheng Zhang, Hongli He, Jianfeng Liu,

Yield loss in the economically important hazelnut (Corylus spp.) occurs through the frequent formation of blank nuts. Although the condition is associated with embryo abortion, we have not yet identified the regulatory genes involved. Therefore, this study aimed to determine the genes related to embryo abortion in hazel. We performed ... Read more >>

Front Plant Sci (Frontiers in plant science)
[2019, 10:1465]

Cited: 0 times

View full text PDF listing >>



Mesenchymal Stem Cell-Derived Extracellular Vesicles Decrease Lung Injury in Mice.

Qi Hao, Varun Gudapati, Antoine Monsel, Jeong H Park, Shuling Hu, Hideya Kato, Jae H Lee, Li Zhou, Hongli He, Jae W Lee,

Human mesenchymal stem cell (MSC) extracellular vesicles (EV) can reduce the severity of bacterial pneumonia, but little is known about the mechanisms underlying their antimicrobial activity. In the current study, we found that bacterial clearance induced by MSC EV in Escherichia coli pneumonia in C57BL/6 mice was associated with high ... Read more >>

J. Immunol. (Journal of immunology (Baltimore, Md. : 1950))
[2019, 203(7):1961-1972]

Cited: 4 times

View full text PDF listing >>



Detection of pulmonary oedema by electrical impedance tomography: validation of previously proposed approaches in a clinical setting.

Zhanqi Zhao, Hongli He, Jingying Luo, Andy Adler, Xiaoqin Zhang, Rongan Liu, Yunping Lan, Sen Lu, Xiaoxiu Luo, Yu Lei, Inez Frerichs, Xiaobo Huang, Knut Möller,

OBJECTIVE:The aim of the present study was to evaluate two previously proposed approaches based on electrical impedance tomography (EIT) to assess pulmonary oedema at the bedside. APPROACH:Fourteen patients with acute respiratory distress syndrome were included and examined prospectively. Patients were rotated laterally along their longitudinal axis from supine to 45-degree ... Read more >>

Physiol Meas (Physiological measurement)
[2019, 40(5):054008]

Cited: 0 times

View full text PDF listing >>



Antibacterial and osteogenesis performances of LL37-loaded titania nanopores in vitro and in vivo.

Xinkun Shen, Mohammed A Al-Baadani, Hongli He, Lina Cai, Zuosu Wu, Litao Yao, Xinghai Wu, Shuyi Wu, Mengyu Chen, Hualin Zhang, Jinsong Liu,

Background: Many studies have shown that the size of nanotube (NT) can significantly affect the behavior of osteoblasts on titanium-based materials. But the weak bonding strength between NT and substrate greatly limits their application. Purpose: The objective of this study was to compare the stability of NT and nanopore (NP) coatings, and ... Read more >>

Int J Nanomedicine (International journal of nanomedicine)
[2019, 14:3043-3054]

Cited: 2 times

View full text PDF listing >>



Introduction of the harpinXooc-encoding gene hrf2 in soybean enhances resistance against the oomycete pathogen Phytophthora sojae.

Lu Niu, Jing Yang, Jinhua Zhang, Hongli He, Guojie Xing, Qianqian Zhao, Dongquan Guo, Li Sui, Xiaofang Zhong, Xiangdong Yang,

Phytophthora root and stem rot (PRR) caused by an oomycete pathogen Phytophthora sojae is one of the most devastating and widespread diseases throughout soybean-producing regions worldwide. The diversity and variability of P. sojae races make effective control of the pathogen challenging. Here, we introduced an elicitor of plant defense response, ... Read more >>

Transgenic Res. (Transgenic research)
[2019, 28(2):257-266]

Cited: 0 times

View full text PDF listing >>



Over-expression of GmKR3, a TIR-NBS-LRR type R gene, confers resistance to multiple viruses in soybean.

Hongwei Xun, Xiangdong Yang, Hongli He, Meng Wang, Peng Guo, Ying Wang, Jinsong Pang, Yingshan Dong, Xianzhong Feng, Shucai Wang, Bao Liu,

KEY MESSAGE:That overexpression of GmKR3 enhances innate virus resistance by stimulating. Soybean mosaic virus (SMV) is found in many soybean production areas, and SMV infection is one of the prevalent viral diseases that can cause significant yield losses in soybean. In plants, resistance (R) genes are involved in pathogen reorganization ... Read more >>

Plant Mol. Biol. (Plant molecular biology)
[2019, 99(1-2):95-111]

Cited: 3 times

View full text PDF listing >>



Increased multiple virus resistance in transgenic soybean overexpressing the double-strand RNA-specific ribonuclease gene PAC1.

Xiangdong Yang, Lu Niu, Wei Zhang, Hongli He, Jing Yang, Guojie Xing, Dongquan Guo, Qianqian Zhao, Xiaofang Zhong, Haiyun Li, Qiyun Li, Yingshan Dong,

Viruses constitute a major constraint to soybean production worldwide and are responsible for significant yield losses every year. Although varying degrees of resistance to specific viral strains has been identified in some soybean genetic sources, the high rate of mutation in viral genomes and mixed infections of different viruses or ... Read more >>

Transgenic Res. (Transgenic research)
[2019, 28(1):129-140]

Cited: 1 time

View full text PDF listing >>



Three new species of the leafhopper genus Processina (Hemiptera: Cicadellidae: Mileewinae) from Thailand.

Hongli He, Maofa Yang, Xiaofei Yu,

Three new species of the leafhopper genus Processina Yang, Deitz Li, 2005 are described from Thailand: Processina chandrai sp. nov., P. topoarmata sp. nov. and P. kamphaengensis sp. nov. A checklist to the species of the genus and a key for their separation are provided. ... Read more >>

Zootaxa (Zootaxa)
[2018, 4531(2):279-287]

Cited: 0 times

View full text PDF listing >>



Enhanced resistance to sclerotinia stem rot in transgenic soybean that overexpresses a wheat oxalate oxidase.

Xiangdong Yang, Jing Yang, Yisheng Wang, Hongli He, Lu Niu, Dongquan Guo, Guojie Xing, Qianqian Zhao, Xiaofang Zhong, Li Sui, Qiyun Li, Yingshan Dong,

Sclerotinia stem rot (SSR), caused by the oxalate-secreting necrotrophic fungal pathogen Sclerotinia sclerotiorum, is one of the devastating diseases that causes significant yield loss in soybean (Glycine max). Until now, effective control of the pathogen is greatly limited by a lack of strong resistance in available commercial soybean cultivars. In ... Read more >>

Transgenic Res. (Transgenic research)
[2019, 28(1):103-114]

Cited: 1 time

View full text PDF listing >>



Improved oil quality in transgenic soybean seeds by RNAi-mediated knockdown of GmFAD2-1B.

Jing Yang, Guojie Xing, Lu Niu, Hongli He, Dongquan Guo, Qian Du, Xueyan Qian, Yao Yao, Haiyun Li, Xiaofang Zhong, Xiangdong Yang,

Soybean oil contains approximately 20% oleic acid and 63% polyunsaturated fatty acids, which limits its uses in food products and industrial applications because of its poor oxidative stability. Increasing the oleic acid content in soybean seeds provides improved oxidative stability and is also beneficial to human health. Endoplasmic reticulum-associated delta-12 ... Read more >>

Transgenic Res. (Transgenic research)
[2018, 27(2):155-166]

Cited: 1 time

View full text PDF listing >>



Robust RNAi-mediated resistance to infection of seven potyvirids in soybean expressing an intron hairpin NIb RNA.

Xiangdong Yang, Lu Niu, Wei Zhang, Hongli He, Jing Yang, Guojie Xing, Dongquan Guo, Qian Du, Xueyan Qian, Yao Yao, Qiyun Li, Yingshan Dong,

Viral pathogens, such as soybean mosaic virus (SMV), are a major constraint in soybean production and often cause significant yield loss and quality deterioration. Engineering resistance by RNAi-mediated gene silencing is a powerful strategy for controlling viral diseases. In this study, a 248-bp inverted repeat of the replicase (nuclear inclusion ... Read more >>

Transgenic Res. (Transgenic research)
[2017, 26(5):665-676]

Cited: 1 time

View full text PDF listing >>



RNAi-mediated SMV P3 cistron silencing confers significantly enhanced resistance to multiple Potyvirus strains and isolates in transgenic soybean.

Xiangdong Yang, Lu Niu, Wei Zhang, Jing Yang, Guojie Xing, Hongli He, Dongquan Guo, Qian Du, Xueyan Qian, Yao Yao, Qiyun Li, Yingshan Dong,

Robust RNAi-mediated resistance to multiple Potyvirus strains and isolates, but not to Secovirus BPMV, was conferred by expressing a short SMV P3 hairpin in soybean plants. Engineering resistance to multiple Potyvirus strains is of great interest because of a wide variability of the virus strains, and mixed infections of multiple ... Read more >>

Plant Cell Rep. (Plant cell reports)
[2018, 37(1):103-114]

Cited: 6 times

View full text PDF listing >>



Over-expression of GmSN1 enhances virus resistance in Arabidopsis and soybean.

Hongli He, Xiangdong Yang, Hongwei Xun, Xue Lou, Shuzhen Li, Zhibin Zhang, Lili Jiang, Yingshan Dong, Shucai Wang, Jinsong Pang, Bao Liu,

GmSN1 enhances virus resistance in plants most likely by affecting the expression of signal transduction and immune response genes. Soybean mosaic virus (SMV) infection causes severe symptom and leads to massive yield loss in soybean (Glycine max). By comparative analyzing gene expression in the SMV-resistant soybean cultivar Rsmv1 and the ... Read more >>

Plant Cell Rep. (Plant cell reports)
[2017, 36(9):1441-1455]

Cited: 0 times

View full text PDF listing >>



Gallium and silicon synergistically promote osseointegration of dental implant in patients with osteoporosis.

Jinsong Liu, Zuosu Wu, Hongli He, Kaiyong Cai, Hualin Zhang, Lihua Xu,

Over the last few decades, a wide variety of dental implants have been successfully placed in jaw bones to restore tooth function. But major challenges still remain in patients with osteoporosis involving compromised osseointegration, and the therapeutic methods is far from optimism. Gallium can directly inhibit bone osteolysis, prevent bone ... Read more >>

Med. Hypotheses (Medical hypotheses)
[2017, 103:35-38]

Cited: 0 times

View full text PDF listing >>



Overexpression of a GmCnx1 gene enhanced activity of nitrate reductase and aldehyde oxidase, and boosted mosaic virus resistance in soybean.

Zheng Zhou, Hongli He, Luping Ma, Xiaoqian Yu, Qian Mi, Jingsong Pang, Guixiang Tang, Bao Liu,

Molybdenum cofactor (Moco) is required for the activities of Moco-dependant enzymes. Cofactor for nitrate reductase and xanthine dehydrogenase (Cnx1) is known to be involved in the biosynthesis of Moco in plants. In this work, a soybean (Glycine max L.) Cnx1 gene (GmCnx1) was transferred into soybean using Agrobacterium tumefaciens-mediated transformation ... Read more >>

PLoS ONE (PloS one)
[2015, 10(4):e0124273]

Cited: 2 times

View full text PDF listing >>



Therapeutic Effects of Bone Marrow-Derived Mesenchymal Stem Cells in Models of Pulmonary and Extrapulmonary Acute Lung Injury.

Ling Liu, Hongli He, Airan Liu, Jingyuan Xu, Jibin Han, Qihong Chen, Shuling Hu, Xiuping Xu, Yingzi Huang, Fengmei Guo, Yi Yang, Haibo Qiu,

Bone marrow-derived mesenchymal stem cells (MSCs) offer a promising therapy for acute lung injury (ALI). However, whether the same MSC treatments possess similar potential for different ALI models is not fully clear. The present study evaluated the distribution and therapeutic effects of intravenous MSC administration for the treatment of intratracheal ... Read more >>

Cell Transplant (Cell transplantation)
[2015, 24(12):2629-2642]

Cited: 12 times

View full text PDF listing >>



Mesenchymal Stem Cells Overexpressing Angiotensin-Converting Enzyme 2 Rescue Lipopolysaccharide-Induced Lung Injury.

Hongli He, Ling Liu, Qihong Chen, Airan Liu, Shixia Cai, Yi Yang, Xiaomin Lu, Haibo Qiu,

Bone marrow-derived mesenchymal stem cells (MSCs), which have beneficial effects in acute lung injury (ALI), can serve as a vehicle for gene therapy. Angiotensin-converting enzyme 2 (ACE2), a counterregulatory enzyme of ACE that degrades angiotensin (Ang) II into Ang 1-7, has a protective role against ALI. Because ACE2 expression is ... Read more >>

Cell Transplant (Cell transplantation)
[2015, 24(9):1699-1715]

Cited: 25 times

View full text PDF listing >>



[Losartan modulates T helper type 1 cells and T helper type 17 cells-mediated responses in a mouse model of lipopolysaccharide-induced acute lung injury].

Jun Liu, Pengshu Zhang, Hongli He, Tao Yu, Ling Liu, Fengmei Guo, Yingzi Huang, Yi Yang, Haibo Qiu,

OBJECTIVE: To assess the effect of losartan, angiotensin II receptor type 1 (AT1) receptor antagonist, on the pulmonary T helper (Th) cell polarization response in acute lung injury (ALI) mice. METHODS: C57BL/6 mice were randomized into control group, ALI group and ALI + losartan group, which respectively were administrated with ... Read more >>

Zhonghua Nei Ke Za Zhi (Zhonghua nei ke za zhi)
[2014, 53(10):804-808]

Cited: 0 times

View full text PDF listing >>



Overexpression of GmAKT2 potassium channel enhances resistance to soybean mosaic virus.

Lian Zhou, Hongli He, Ruifang Liu, Qiang Han, Huixia Shou, Bao Liu,

BACKGROUND: Soybean mosaic virus (SMV) is the most prevalent viral disease in many soybean production areas. Due to a large number of SMV resistant loci and alleles, SMV strains and the rapid evolution in avirulence/effector genes, traditional breeding for SMV resistance is complex. Genetic engineering is an effective alternative method ... Read more >>

BMC Plant Biol. (BMC plant biology)
[2014, 14:154]

Cited: 10 times

View full text PDF listing >>



Wnt5a through noncanonical Wnt/JNK or Wnt/PKC signaling contributes to the differentiation of mesenchymal stem cells into type II alveolar epithelial cells in vitro.

Airan Liu, Song Chen, Shixia Cai, Liang Dong, Le Liu, Yi Yang, Fengmei Guo, Xiaomin Lu, Hongli He, Qihong Chen, Shuling Hu, Haibo Qiu,

The differentiation of mesenchymal stem cells (MSCs) into type II alveolar epithelial (AT II) cells is critical for reepithelization and recovery in acute respiratory distress syndrome (ARDS), and Wnt signaling was considered to be the underlying mechanisms. In our previous study, we found that canonical Wnt pathway promoted the differentiation ... Read more >>

PLoS ONE (PloS one)
[2014, 9(3):e90229]

Cited: 23 times

View full text PDF listing >>



[Effects of sucralfate and acid-suppressive drugs on preventing ventilator- associated pneumonia of mechanically ventilated patients: a meta-analysis].

Hongli He, Shuling Hu, Qihong Chen, Ling Liu, Yingzi Huang, Yi Yang, Haibo Qiu,

OBJECTIVE: To evaluate the effect of sucralfate and acid-suppressive drugs on preventing ventilator-associated pneumonia (VAP) in mechanically ventilated patients. METHODS: All randomized controlled trials (RCTs), which studied the effect of sucralfate and acid-suppressive drugs on the incidence of VAP in mechanically ventilated patients, were searched from PubMed, Embase and the ... Read more >>

Zhonghua Nei Ke Za Zhi (Zhonghua nei ke za zhi)
[2014, 53(1):48-54]

Cited: 2 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1733 s