Full Text Journal Articles by
Author Hoda Al Booz


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Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial.

Hisham Mehanna, Max Robinson, Andrew Hartley, Anthony Kong, Bernadette Foran, Tessa Fulton-Lieuw, Matthew Dalby, Pankaj Mistry, Mehmet Sen, Lorcan O'Toole, Hoda Al Booz, Karen Dyker, Rafael Moleron, Stephen Whitaker, Sinead Brennan, Audrey Cook, Matthew Griffin, Eleanor Aynsley, Martin Rolles, Emma De Winton, Andrew Chan, Devraj Srinivasan, Ioanna Nixon, Joanne Grumett, C René Leemans, Jan Buter, Julia Henderson, Kevin Harrington, Christopher McConkey, Alastair Gray, Janet Dunn, ,

<h4>Background</h4>The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer, a disease affecting younger patients, is rapidly increasing. Cetuximab, an epidermal growth factor receptor inhibitor, has been proposed for treatment de-escalation in this setting to reduce the toxicity of standard cisplatin treatment, but no randomised evidence exists for the efficacy of this ... Read more >>

Lancet (Lancet (London, England))
[2019, 393(10166):51-60]

Cited: 69 times

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Completion surgery after chemoradiotherapy for cervical cancer - is there a role? UK Cancer Centre experience of hysterectomy post chemo-radiotherapy treatment for cervical cancer.

Sarah L Platt, Amit Patel, Pauline J Humphrey, Hoda Al-Booz, Jo Bailey,

The standard treatment for locally advanced cervical cancer is chemo-radiotherapy. The presence of the residual disease after treatment is directly related to the relapse risk and to poor survival. There is a lack of consensus on the role of a subsequent surgery due to morbidity concerns. Oncological and peri-operative outcomes ... Read more >>

J Obstet Gynaecol (Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology)
[2019, 39(1):68-73]

Cited: 1 time

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PET-CT Surveillance versus Neck Dissection in Advanced Head and Neck Cancer.

Hisham Mehanna, Wai-Lup Wong, Christopher C McConkey, Joy K Rahman, Max Robinson, Andrew G J Hartley, Christopher Nutting, Ned Powell, Hoda Al-Booz, Martin Robinson, Elizabeth Junor, Mohammed Rizwanullah, Sandra V von Zeidler, Hulya Wieshmann, Claire Hulme, Alison F Smith, Peter Hall, Janet Dunn, ,

<h4>Background</h4>The role of image-guided surveillance as compared with planned neck dissection in the treatment of patients with squamous-cell carcinoma of the head and neck who have advanced nodal disease (stage N2 or N3) and who have received chemoradiotherapy for primary treatment is a matter of debate.<h4>Methods</h4>In this prospective, randomized, controlled ... Read more >>

N Engl J Med (The New England journal of medicine)
[2016, 374(15):1444-1454]

Cited: 103 times

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Geographic variation in human papillomavirus-related oropharyngeal cancer: Data from 4 multinational randomized trials.

Hisham Mehanna, Natalie Franklin, Natalie Compton, Max Robinson, Ned Powell, Nigel Biswas-Baldwin, Vindh Paleri, Andrew Hartley, Lydia Fresco, Hoda Al-Booz, Elizabeth Junor, Iman El-Hariry, Sally Roberts, Kevin Harrington, K Kian Ang, Janet Dunn, Ciaran Woodman,

<h4>Background</h4>There are variations in the proportions of head and neck cancers caused by the human papillomavirus (HPV) between countries and regions. It is unclear if these are true variations or due to different study designs and assays.<h4>Methods</h4>We tested formalin-fixed paraffin-embedded diagnostic biopsies for p16 immunohistochemistry and HPV-DNA (by polymerase chain ... Read more >>

Head Neck (Head & neck)
[2016, 38 Suppl 1:E1863-9]

Cited: 11 times

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Brachytherapy in endometrial cancer: quantification of air gaps around a vaginal cylinder.

Alison L Cameron, Paul Cornes, Hoda Al-Booz,

PURPOSE: Vaginal vault brachytherapy, prescribed to 0.5 cm, is used in endometrial cancer postoperatively to reduce the risk of vault recurrence. However, it is unknown if the vaginal mucosa is closely opposed to the vaginal cylinder, or if air gaps lift the mucosa from the cylinder. The aim of this ... Read more >>

Brachytherapy (Brachytherapy)
[2008, 7(4):355-358]

Cited: 14 times

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Sigmoid colon is an unexpected organ at risk in brachytherapy for cervix cancer.

Hoda Al-Booz, Ion Boiangiu, Helen Appleby, Chris French, Helen Coomber, Pauline Humphery, Paul Cornes,

PURPOSE:To identify organs at risk (OAR) and analyze the dose volume histograms (DVHs) for intracavitary brachytherapy in cancer of the cervix. Late toxicities are our concern in treatment of cancer cervix especially as it is presenting in younger age population. MATERIAL AND METHODS:Patients with cancer of the cervix were treated ... Read more >>

J Egypt Natl Canc Inst (Journal of the Egyptian National Cancer Institute)
[2006, 18(2):156-160]

Cited: 7 times

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Spinal cord doses in palliative lung radiotherapy schedules.

Hoda Al-Booz, Carol Parton,

<h4>Aim</h4>We aim to check the safety of the standard palliative radiotherapy techniques by using the Linear quadratic model for a careful estimation of the doses received by the spinal cord, in all standard palliative lung radiotherapy fields and fractionation.<h4>Material and methods</h4>All patients surveyed at this prospective audit were treated with ... Read more >>

J Egypt Natl Canc Inst (Journal of the Egyptian National Cancer Institute)
[2006, 18(2):161-166]

Cited: 0 times

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