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Author Hiroshi Hayashi

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A 15-Month-old Boy With Kawasaki Disease-like Symptoms.

Hiroshi Hayashi, Kazuhiro Uda, Keiji Akamine, Nanako Kawata, Shogo Akahoshi, Masaki Shimizu, Yuho Horikoshi, Hiroshi Hataya,

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(2):173-174]

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Monitoring of residual antibacterial agents in animal and fishery products in Tokyo from 2003 to 2019: application and verification of a screening strategy based on microbiological methods.

Hiroshi Koike, Maki Kanda, Hiroshi Hayashi, Yoko Matsushima, Takayuki Nakajima, Souichi Yoshikawa, Yumi Ohba, Momoka Hayashi, Chieko Nagano, Kotaro Sekimura, Kenji Otsuka, Tsuneo Hashimoto, Takeo Sasamoto,

Residual antibacterial agents in 5909 animal and fishery products in Tokyo, Japan, were investigated over 17 consecutive years (2003-2019). Monitoring of 32 antibacterial agents (lincosamides, macrolides, penicillins, quinorones and tetracyclines) per product was accomplished via two steps: screening (by microbiological methods) and confirmation (by instrumental methods). Microbiological screening methods identified ... Read more >>

Food Addit Contam Part B Surveill (Food additives & contaminants. Part B, Surveillance)
[2021, :1-8]

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Usefulness of the gracilis muscle flap for reconstruction of large perineal defects following total pelvic exenteration with sacrectomy.

Kazuhito Sasaki, Fuyo Yoshimi, Hiroshi Kawasaki, Hiroshi Hayashi, Masaya Hiyoshi, Hideo Nagai, Soichiro Ishihara,

ANZ J Surg (ANZ journal of surgery)
[2021, :]

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Comparison of Alzheimer's disease patients and healthy controls in the easy Z-score imaging system with differential image reconstruction methods using SPECT/CT: verification using normal database of our institution.

Makoto Ohba, Ryota Kobayashi, Kazukuni Kirii, Kyosuke Fujita, Chika Kanezawa, Hiroshi Hayashi, Shinobu Kawakatsu, Koichi Otani, Masafumi Kanoto, Koji Suzuki,

<h4>Objective</h4>The easy Z-score imaging system (eZIS) analysis is used for the diagnosis of dementia by cerebral blood flow on single photon emission computed tomography (SPECT). Differences in the acquisition and reconstruction conditions in SPECT may affect the eZIS analysis results. The present study aimed to construct our institutional normal database ... Read more >>

Ann Nucl Med (Annals of nuclear medicine)
[2021, :]

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Clinical outcomes of ablation versus non-ablation therapy for atrial fibrillation in Japan: analysis of pooled data from the AF Frontier Ablation Registry and SAKURA AF Registry.

Kazuki Iso, Koichi Nagashima, Masaru Arai, Ryuta Watanabe, Katsuaki Yokoyama, Naoya Matsumoto, Takayuki Otsuka, Shinya Suzuki, Akio Hirata, Masato Murakami, Mitsuru Takami, Masaomi Kimura, Hidehira Fukaya, Shiro Nakahara, Takeshi Kato, Hiroshi Hayashi, Yu-Ki Iwasaki, Wataru Shimizu, Ikutaro Nakajima, Tomoo Harada, Junjiroh Koyama, Ken Okumura, Michifumi Tokuda, Teiichi Yamane, Kojiro Tanimoto, Yukihiko Momiyama, Noriko Nonoguchi, Kyoko Soejima, Koichiro Ejima, Nobuhisa Hagiwara, Masahide Harada, Kazumasa Sonoda, Masaru Inoue, Koji Kumagai, Hidemori Hayashi, Yoshinao Yazaki, Kazuhiro Satomi, Yuji Watari, Yasuo Okumura, ,

Whether ablation for atrial fibrillation (AF) is, in terms of clinical outcomes, beneficial for Japanese patients has not been clarified. Drawing data from 2 Japanese AF registries (AF Frontier Ablation Registry and SAKURA AF Registry), we compared the incidence of clinically relevant events (CREs), including stroke/transient ischemic attack (TIA), major ... Read more >>

Heart Vessels (Heart and vessels)
[2020, :]

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Prognostic impact of newly detected atrial fibrillation in patients with hypertrophic cardiomyopathy following cardiac implantable electronic device implantation.

Hiroshi Hayashi, Yu-Ki Iwasaki, Toshiki Arai, Rei Mimuro, Masato Hachisuka, Yujin Maru, Yuhi Fujimoto, Eiichiro Oka, Kanako Hagiwara, Yoichi Imori, Teppei Yamamoto, Hiroshige Murata, Kenji Yodogawa, Hitoshi Takano, Wataru Shimizu,

Atrial fibrillation (AF) is the most common arrhythmia in patients with hypertrophic cardiomyopathy (HCM). The present study aimed to investigate the incidence and prognostic impact of newly detected AF after cardiac implantable electronic device (CIED) implantation with HCM patients. Fifty-six patients (33 men, age 57 ± 17 years) with HCM who underwent CIED ... Read more >>

Heart Vessels (Heart and vessels)
[2020, :]

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Clinical Outcomes of Off-Label Underdosing of Direct Oral Anticoagulants After Ablation for Atrial Fibrillation.

Yuji Wakamatsu, Koichi Nagashima, Ryuta Watanabe, Masaru Arai, Katsuaki Yokoyama, Naoya Matsumoto, Takayuki Otsuka, Shinya Suzuki, Akio Hirata, Masato Murakami, Mitsuru Takami, Masaomi Kimura, Hidehira Fukaya, Shiro Nakahara, Takeshi Kato, Hiroshi Hayashi, Yu-Ki Iwasaki, Wataru Shimizu, Ikutaro Nakajima, Tomoo Harada, Junjiroh Koyama, Ken Okumura, Michifumi Tokuda, Teiichi Yamane, Kojiro Tanimoto, Yukihiko Momiyama, Noriko Nonoguchi, Kyoko Soejima, Koichiro Ejima, Nobuhisa Hagiwara, Masahide Harada, Kazumasa Sonoda, Masaru Inoue, Koji Kumagai, Hidemori Hayashi, Yoshinao Yazaki, Kazuhiro Satomi, Yuji Watari, Yasuo Okumura,

Direct oral anticoagulants (DOACs) are sometimes prescribed at off-label under-doses for patients who have undergone ablation for atrial fibrillation (AF). This practice may be an attempt to balance the risk of bleeding against that of stroke or AF recurrence.We examined outcomes of 1163 patients who continued use of a DOAC ... Read more >>

Int Heart J (International heart journal)
[2020, 61(6):1165-1173]

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Transvenous implantable cardioverter-defibrillator implantation in a patient with arrhythmogenic cardiomyopathy and massive right atrial thrombus.

Hiroshi Hayashi, Yu-Ki Iwasaki, Toshiki Seki, Kanako Hagiwara, Yasuo Miyagi, Wataru Shimizu,

HeartRhythm Case Rep (HeartRhythm case reports)
[2020, 6(12):951-954]

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Recognition of the coronavirus disease 2019 pandemic and face mask wearing in patients with Alzheimer's disease: an investigation at a medical centre for dementia in Japan.

Ryota Kobayashi, Hiroshi Hayashi, Shinobu Kawakatsu, Daichi Morioka, Satomi Aso, Masayuki Kimura, Koichi Otani,

Psychogeriatrics (Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society)
[2020, 20(6):923-925]

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Familial dementia with Lewy bodies with VPS13C mutations.

Ryota Kobayashi, Hiroya Naruse, Shingo Koyama, Shinobu Kawakatsu, Hiroshi Hayashi, Hiroyuki Ishiura, Jun Mitsui, Yasuyuki Ohta, Tatsushi Toda, Shoji Tsuji, Koichi Otani,

Parkinsonism Relat Disord (Parkinsonism & related disorders)
[2020, 81:31-33]

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Recognition of the coronavirus disease 2019 pandemic and face mask wearing in patients with Alzheimer's disease: an investigation at a medical centre for dementia in Japan

Ryota Kobayashi, Hiroshi Hayashi, Shinobu Kawakatsu, Daichi Morioka, Satomi Aso, Masayuki Kimura, Koichi Otani,

Psychogeriatrics (Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society)
[2020, :]

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Placebo-Controlled, Double-Blind Study of Empagliflozin (EMPA) and Implantable Cardioverter-Defibrillator (EMPA-ICD) in Patients with Type 2 Diabetes (T2DM): Rationale and Design.

Shinya Fujiki, Kenichi Iijima, Masaaki Okabe, Shinichi Niwano, Kenichi Tsujita, Shigeto Naito, Kenji Ando, Kengo Kusano, Ritsushi Kato, Junichi Nitta, Tetsuji Miura, Takeshi Mitsuhashi, Kazuomi Kario, Yusuke Kondo, Masaki Ieda, Nobuhisa Hagiwara, Toyoaki Murohara, Kazuyoshi Takahashi, Hirofumi Tomita, Yasuchika Takeishi, Toshihisa Anzai, Wataru Shimizu, Masafumi Watanabe, Yoshihiro Morino, Takeshi Kato, Hiroshi Tada, Yoshihisa Nakagawa, Masafumi Yano, Koji Maemura, Takeshi Kimura, Hisako Yoshida, Keiko Ota, Takahiro Tanaka, Nobutaka Kitamura, Koichi Node, Yoshifusa Aizawa, Ippei Shimizu, Daisuke Izumi, Kazuyuki Ozaki, Tohru Minamino, ,

<h4>Introduction</h4>Type 2 diabetes (T2DM) is associated with cardiovascular death, including sudden cardiac death due to arrhythmias. Patients with an implantable cardioverter-defibrillator (ICD) are also at high risk of developing a clinically significant ventricular arrhythmia. It has been reported that sodium-glucose cotransporter 2 (SGLT2) inhibitors can reduce cardiovascular deaths; however, the physiological mechanisms ... Read more >>

Diabetes Ther (Diabetes therapy : research, treatment and education of diabetes and related disorders)
[2020, 11(11):2739-2755]

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Efficacy of bezafibrate for preventing myopathic attacks in patients with very long-chain acyl-CoA dehydrogenase deficiency.

Hideaki Shiraishi, Kenji Yamada, Kiyoshi Egawa, Mika Ishige, Fumihiro Ochi, Asami Watanabe, Sanae Kawakami, Kazuyo Kuzume, Kenji Watanabe, Koji Sameshima, Kiyotaka Nakamagoe, Akira Tamaoka, Naoko Asahina, Saki Yokoshiki, Keiko Kobayashi, Takashi Miyakoshi, Koji Oba, Toshiyuki Isoe, Hiroshi Hayashi, Seiji Yamaguchi, Norihiro Sato,

<h4>Background</h4>Very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) is a mitochondrial fatty acid oxidation disorder that causes episodic attacks, such as general fatigue, hypotonia, myalgia, and rhabdomyolysis accompanied by lack of energy. As yet, there are no preventative drugs for these VLCADD-associated metabolic attacks.<h4>Patients and methods</h4>We conducted an open-label, non-randomized, multi-center study ... Read more >>

Brain Dev (Brain & development)
[2021, 43(2):214-219]

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Value of laboratory results in addition to vital signs in a machine learning algorithm to predict in-hospital cardiac arrest: A single-center retrospective cohort study.

Ryo Ueno, Liyuan Xu, Wataru Uegami, Hiroki Matsui, Jun Okui, Hiroshi Hayashi, Toru Miyajima, Yoshiro Hayashi, David Pilcher, Daryl Jones,

<h4>Background</h4>Although machine learning-based prediction models for in-hospital cardiac arrest (IHCA) have been widely investigated, it is unknown whether a model based on vital signs alone (Vitals-Only model) can perform similarly to a model that considers both vital signs and laboratory results (Vitals+Labs model).<h4>Methods</h4>All adult patients hospitalized in a tertiary care ... Read more >>

PLoS One (PloS one)
[2020, 15(7):e0235835]

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Detection of reduced dopamine transporter availability by 123 I-N-omega-fluoropropyl-2-beta-carbomethoxy-3-beta (4-iodophenyl) nortropane single-photon emission computed tomography in a patient of frontotemporal dementia with motor neuron disease.

Ryota Kobayashi, Hiroshi Hayashi, Shinobu Kawakatsu, Hiroki Nagasawa, Shingo Koyama, Kenichi Ishizawa, Koichi Otani,

Psychogeriatrics (Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society)
[2020, 20(5):799-801]

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Early prediction model of organ/space surgical site infection after elective gastrointestinal or hepatopancreatobiliary cancer surgery.

Jun Okui, Ryo Ueno, Hiroki Matsui, Wataru Uegami, Hiroshi Hayashi, Toru Miyajima, Hiroshi Kusanagi,

BACKGROUND:Organ/space SSI is a significant clinical problem. However, early detection of organ/space SSI is difficult, and previous predictive models are limited in their prognostic ability. We aimed to develop and validate a prediction model of organ/space surgical site infection (SSI) using postoperative day 3 laboratory data in patients who underwent ... Read more >>

J Infect Chemother (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2020, 26(9):916-922]

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Utility of Easy Z-Score Imaging System-Assisted SPECT in Detecting Onset Age-Dependent Decreases in Cerebral Blood Flow in the Posterior Cingulate Cortex, Precuneus, and Parietal Lobe in Alzheimer's Disease with Amyloid Accumulation.

Hiroshi Hayashi, Ryota Kobayashi, Shinobu Kawakatsu, Daichi Morioka, Koichi Otani,

<h4>Background</h4>Easy <i>Z</i>-score imaging system (eZIS)-assisted SPECT accurately detects decreases in cerebral blood flow in the posterior cingulate cortex (PCC), precuneus, and parietal lobe, the cerebral regions deeply implicated in Alzheimer's disease (AD). Several studies suggested onset age-dependent decreases in cerebral blood flow in these regions in AD, but these studies ... Read more >>

Dement Geriatr Cogn Dis Extra (Dementia and geriatric cognitive disorders extra)
[2020, 10(2):63-68]

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Significance of fragmented QRS complexes for predicting new-onset atrial fibrillation after cavotricuspid isthmus-dependent atrial flutter ablation.

Yuhi Fujimoto, Kenji Yodogawa, Eiichiro Oka, Hiroshi Hayashi, Teppei Yamamoto, Hiroshige Murata, Yu-Ki Iwasaki, Meiso Hayashi, Wataru Shimizu,

<h4>Background</h4>Atrial fibrillation (AF) and cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) are 2 separate entities that coexist in a significant proportion of patients. In patients with CTI ablation of AFL, the decision to hold anticoagulation often becomes an issue.<h4>Objectives</h4>This study aimed to describe the incidence of the development of AF after ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(9):1493-1499]

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Characterization of plant immunity-activating mechanism by a pyrazole derivative.

Miyuki Kusajima, Moeka Fujita, Hiromoto Yamakawa, Tsukasa Ushiwatari, Takamasa Mori, Kazuki Tsukamoto, Hiroshi Hayashi, Akiko Maruyama-Nakashita, Fang-Sik Che, Hideo Nakashita,

A newly identified chemical, 4-{3-[(3,5-dichloro-2-hydroxybenzylidene)amino]propyl}-4,5-dihydro-1H-pyrazol-5-one (BAPP) was characterized as a plant immunity activator. BAPP enhanced disease resistance in rice against rice blast disease and expression of a defense-related gene without growth inhibition. Moreover, BAPP was able to enhance disease resistance in dicotyledonous tomato and Arabidopsis plants against bacterial pathogen without ... Read more >>

Biosci Biotechnol Biochem (Bioscience, biotechnology, and biochemistry)
[2020, 84(7):1427-1435]

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Phenoconversion from rapid eye movement sleep behaviour disorder to multiple system atrophy is predicted by abnormal dopamine transporter imaging combined with normal 123 I-metaiodobenzylguanidine myocardial scintigraphy: a case report.

Ryota Kobayashi, Hiroshi Hayashi, Shinobu Kawakatsu, Daichi Morioka, Chifumi Iseki, Kenichi Ishizawa, Koichi Otani,

Psychogeriatrics (Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society)
[2020, 20(5):807-809]

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Equivalent clinical outcome after vitrified-thawed blastocyst transfer using semi-automated embryo vitrification system compared with manual vitrification method.

Atsuko Miwa, Yukiko Noguchi, Kayo Hosoya, Yuusuke Mori, Takuma Sato, Yuta Kasahara, Miwa Hidaka, Hiroshi Hayashi,

Purpose:This study compared Gavi®, an automated system for the equilibration and dehydration steps of vitrification, and a manual vitrification procedure in terms of effects on clinical outcomes. Methods:The authors retrospectively compared survival rate, and clinical and perinatal outcomes after vitrified-thawed single blastocyst transfer between Gavi® (G method) in 398 cases ... Read more >>

Reprod Med Biol (Reproductive medicine and biology)
[2020, 19(2):164-170]

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Idiopathic ventricular fibrillation and the V1764fsX1786 frameshift mutation of the SCN5A gene in a myotonic dystrophy type 1 patient.

Takashi Shimoyama, Hiroshi Hayashi, Fumiaki Suzuki, Yasuhiro Nishiyama, Yoshihiro Miyamoto, Takeshi Aiba, Wataru Shimizu, Kazumi Kimura,

Myotonic dystrophy type 1 (DM1) is an autosomal dominant inherited muscular dystrophy caused by an expanded CTG repeat in the dystrophia myotonica protein kinase (DMPK) gene. Cardiac involvements in DM1 are characterized by cardiac conduction delays and atrial or ventricular tachycardia, which increase the risk of sudden cardiac death when ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 74:242-244]

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[Determination of Antibacterial Agents for Animals in Swine Muscles by Microbiological Screening and LC-MS/MS].

Kotaro Sekimura, Maki Kanda, Hiroshi Hayashi, Yoko Matsushima, Souichi Yoshikawa, Yumi Ohba, Hiroshi Koike, Momoka Hayashi, Chieko Nagano, Kenji Otsuka, Tsuneo Hashimoto, Takeo Sasamoto,

The determination of antibacterial agents for animals in swine muscles was improved by microbiological screening and liquid chromatography-mass spectrometry (LC-MS/MS) analyses. In the first instance, the residual drugs were extracted from the samples using the Na<sub>2</sub>EDTA-McIlvaine buffer (pH 6.0). Subsequently, the agents were purified utilizing a PLS-3 cartridge and extracted ... Read more >>

Shokuhin Eiseigaku Zasshi (Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
[2020, 61(4):109-118]

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[Prevalence of Cereulide-Producing Bacillus cereus in Pasteurized Milk].

Yukako Shimojima, Yukihiro Kodo, Kana Soeda, Hiroshi Koike, Maki Kanda, Hiroshi Hayashi, Yukari Nishino, Rie Fukui, Sumiyo Kuroda, Akihiko Hirai, Jun Suzuki, Kenji Sadamasu,

To recognize the risk of Bacillus cereus in pasteurized milk, we investigated the prevalence of B. cereus and the rate of the production of cereulide from B. cereus isolates. B. cereus was found in 66 out of 101 (65.3%) domestically pasteurized milk samples in Japan. The ces gene was identified ... Read more >>

Shokuhin Eiseigaku Zasshi (Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
[2020, 61(5):178-182]

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Thought visualization occurring in a patient of dementia with Lewy bodies.

Ryota Kobayashi, Daichi Morioka, Hiroshi Hayashi, Akihito Suzuki, Koichi Otani,

Asian J Psychiatr (Asian journal of psychiatry)
[2020, 48:101882]

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