Full Text Journal Articles by
Author Hermann Haller

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Single-Cell versus Single-Nucleus: Transcriptome differences in murine kidney after ischemia-reperfusion injury.

Svenja Gaedcke, Julius Sinning, Oliver Dittrich-Breiholz, Hermann Haller, Inga Soerensen-Zender, Chieh Ming Liao, Alexandra Nordlohne, Payel Sen, Sibylle von Vietinghoff, David S DeLuca, Roland Schmitt,

The kidney is a complex organ, which consists of multiple components with highly diverse cell types. A detailed understanding of these cell types in health and disease is crucial for future development of preventive and curative treatment strategies. In recent years, single cell RNA sequencing (scRNAseq) and single nucleus RNA ... Read more >>

Am J Physiol Renal Physiol (American journal of physiology. Renal physiology)
[2022, :]

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Induction of ferroptosis selectively eliminates senescent tubular cells.

Chieh M Liao, Vera C Wulfmeyer, Rongjun Chen, Zulrahman Erlangga, Julius Sinning, Anne von Mässenhausen, Inga Sörensen-Zender, Kristina Beer, Sibylle von Vietinghoff, Hermann Haller, Andreas Linkermann, Anette Melk, Roland Schmitt,

The accumulation of senescent cells is an important contributor to kidney aging, chronic renal disease, and poor outcome after kidney transplantation. Approaches to eliminate senescent cells with senolytic compounds have been proposed as novel strategies to improve marginal organs. While most existing senolytics induce senescent cell clearance by apoptosis, we ... Read more >>

Am J Transplant (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2022, :]

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