Full Text Journal Articles by
Author Henry Mandeville

Advertisement

Find full text journal articles






High grade gliomas in young children: The South Thames Neuro-Oncology unit experience and recent advances in molecular biology and targeted therapies.

Janice Pearce, Komel Khabra, Henry Nanji, Joanna Stone, Karen Powell, Danielle Martin, Bassel Zebian, Samantha Hettige, Zita Reisz, Istvan Bodi, Safa Al-Sarraj, Leslie R Bridges, Matthew Clarke, Chris Jones, Henry C Mandeville, Sucheta Vaidya, Lynley V Marshall, Fernando Carceller,

High grade gliomas (HGG) have a dismal prognosis with survival rates of 15-35%. Approximately 10-12% of pediatric HGG occur in young children and their molecular biology and clinical outcomes differ from those arising at older ages. We report on four children aged <5 years newly diagnosed with non-brainstem HGG between 2011 ... Read more >>

Pediatr Hematol Oncol (Pediatric hematology and oncology)
[2021, :1-15]

Cited: 0 times

View full text PDF listing >>



Rhabdomyosarcoma.

Raphael L Yechieli, Henry C Mandeville, Susan M Hiniker, Valerie Bernier-Chastagner, Susan McGovern, Giovanni Scarzello, Suzanne Wolden, Alison Cameron, John Breneman, Raquel Davila Fajardo, Sarah S Donaldson,

Rhabdomyosarcoma is a heterogeneous disease both in presentation and histology. Improvements in a multimodality therapy resulted in the improved overall survival for patients with a low-risk and intermediate-risk disease but not for patients with a metastatic disease. We reviewed and contrasted the North American and European practice patterns, though ultimately ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68 Suppl 2:e28254]

Cited: 0 times

View full text PDF listing >>



Advertisement

Non-rhabdomyosarcoma soft-tissue sarcoma.

Sarah A Milgrom, Lynn Million, Henry Mandeville, Akmal Safwat, Ralph P Ermoian, Stephanie Terezakis,

Non-rhabdomyosarcoma soft-tissue sarcomas (NRSTS) comprise 4% of childhood cancers and consist of numerous histologic subtypes. Prognostic factors associated with poor outcome include high histologic grade, large tumor size, presence of metastases, and unresectability. Complete surgical resection is critical for the best oncologic outcomes and is prioritized in treatment algorithms. The ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68 Suppl 2:e28279]

Cited: 0 times

View full text PDF listing >>



Quality assurance in radiation oncology.

Thomas J FitzGerald, David Followill, Fran Laurie, Tom Boterberg, Richard Hanusik, Sandra Kessel, Kathryn Karolczuk, Matthew Iandoli, Kenneth Ulin, Karen Morano, Maryann Bishop-Jodoin, Stephen Kry, Jessica Lowenstein, Andrea Molineu, Janaki Moni, M Giulia Cicchetti, Fred Prior, Joel Saltz, Ashish Sharma, Henry C Mandeville, Valerie Bernier-Chastagner, Geert Janssens,

The Children's Oncology Group (COG) has a strong quality assurance (QA) program managed by the Imaging and Radiation Oncology Core (IROC). This program consists of credentialing centers and providing real-time management of each case for protocol compliant target definition and radiation delivery. In the International Society of Pediatric Oncology (SIOP), ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68 Suppl 2:e28609]

Cited: 0 times

View full text PDF listing >>



Rapid 4D-MRI reconstruction using a deep radial convolutional neural network: Dracula.

Joshua N Freedman, Oliver J Gurney-Champion, Simeon Nill, Anna-Maria Shiarli, Hannah E Bainbridge, Henry C Mandeville, Dow-Mu Koh, Fiona McDonald, Marc Kachelrieß, Uwe Oelfke, Andreas Wetscherek,

<h4>Background and purpose</h4>4D and midposition MRI could inform plan adaptation in lung and abdominal MR-guided radiotherapy. We present deep learning-based solutions to overcome long 4D-MRI reconstruction times while maintaining high image quality and short scan times.<h4>Methods</h4>Two 3D U-net deep convolutional neural networks were trained to accelerate the 4D joint MoCo-HDTV ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2021, 159:209-217]

Cited: 0 times

View full text PDF listing >>



Inter-clinician delineation variation for a new highly-conformal flank target volume in children with renal tumors: A SIOP-Renal Tumor Study Group international multicenter exercise.

Joeri Mul, Patrick Melchior, Enrica Seravalli, Daniel Saunders, Stephanie Bolle, Alison L Cameron, Kristin Gurtner, Semi Harrabi, Yasmin Lassen-Ramshad, Naomi Lavan, Henriette Magelssen, Henry Mandeville, Tom Boterberg, Petra S Kroon, Alexis N T J Kotte, Bianca A W Hoeben, Peter S N van Rossum, Martine van Grotel, Norbert Graf, Marry M van den Heuvel-Eibrink, Christian Rübe, Geert O Janssens,

<h4>Background and purpose</h4>Recently, the SIOP-RTSG developed a highly-conformal flank target volume definition for children with renal tumors. The aims of this study were to evaluate the inter-clinician delineation variation of this new target volume definition in an international multicenter setting and to explore the necessity of quality assurance.<h4>Materials and methods</h4>Six ... Read more >>

Clin Transl Radiat Oncol (Clinical and translational radiation oncology)
[2021, 28:39-47]

Cited: 0 times

View full text PDF listing >>



Determining the incidence of interstitial pneumonitis and chronic kidney disease following full intensity haemopoetic stem cell transplant conditioned using a forward-planned intensity modulated total body irradiation technique.

Emily Durie, Emma Nicholson, Chloe Anthias, Emma M Dunne, Mike Potter, Mark Ethell, Christina Messiou, Joy Brennan, Sally Eagle, James Talbot, Gregory Smyth, Westley Ingram, Frank Saran, Henry C Mandeville,

<h4>Purpose/objective</h4>Total body irradiation (TBI) remains a key component of conditioning for allogeneic haemopoietic stem cell transplant (HSCT), with interstitial pneumonitis (IP) and chronic kidney disease (CKD) important late sequelae. We undertook a retrospective service evaluation of TBI patients treated with a forward-planned intensity modulated radiotherapy technique (FP IMRT).<h4>Material/methods</h4>74 adult patients ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2021, 158:97-103]

Cited: 0 times

View full text PDF listing >>



MBRS-33. TEMPORARY RESTORATION OF p53 ACTIVITY DURING FRACTIONATED RADIOTHERAPY IN A GROUP3 MEDULLOBLASTOMA GEMM REPRESENTS A POWERFUL TOOL FOR RADIOBIOLOGY STUDIES

Alaide Morcavallo, Henry Mandeville, Karen Barker, Stacey Richardson, Janet Lindsey, Nikita Lockett, Jessica K R Boult, Simon P Robinson, Uwe Oelfke, Daniel Williamson, Steven C Clifford, Louis Chesler,

Abstract TP53 pathway alterations are well-described events in medulloblastoma (MB) and are predictive of poor clinical outcome. Alterations are rare at diagnosis in Group3 (Gr3) and Group4, but enriched in Sonic Hedgehog and WNT subgroups. However, TP53 mutations are observed in all subgroups at relapse. Radiation therapy, along with surgery ... Read more >>

Neuro Oncol (Neuro-oncology)
[2020, 22(Suppl 3):iii404-iii404]

Cited: 0 times

View full text PDF listing >>



Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG

Diana Carvalho, Sara Temelso, Alan Mackay, Helen Pemberton, Rebecca Rogers, Ketty Kessler, Elisa Izquierdo, Lynn Bjerke, Janat Fazal Salom, Matthew Clarke, Yura Grabovska, Anna Burford, Nagore Gene Olaciregui, Jessica KR Boult, Valeria Molinari, Mariama Fofana, Paula Proszek, Elisabet Potente, Kathryn Taylor, Christopher Chandler, Bassel Zebian, Ranj Bhangoo, Andrew Martin, Bassam Dabbous, Simon Stapleton, Samantha Hettige, Lynley Marshall, Fernando Carceller, Henry Mandeville, Sucheta Vaidya, Safa Al-Sarraj, Leslie Bridges, Robert Johnston, Jane Cryan, Michael Farrell, Darach Crimmins, John Caird, Jane Pears, Giulia Pericoli, Evelina Miele, Angela Mastronuzzi, Franco Locatelli, Andrea Carai, Simon Robinson, Mike Hubank, Michelle Monje, Andrew Moore, Timothy EG Hassall, Angel Montero Carcaboso, Christopher Lord, Mara Vinci, Chris Jones,

<h4>ABSTRACT</h4> Paediatric high grade glioma and diffuse midline glioma (including DIPG) are comprised of multiple biological and clinical subgroups, the majority of which urgently require novel therapies. Patient-derived in vitro primary cell cultures represent potentially useful tools for mechanistic and preclinical investigation based upon their retention of key features of ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



GCT-61. CORRELATION OF PATTERNS OF DISEASE RECURRENCE WITH RADIOTHERAPY TECHNIQUES AND DOSE IN INTRACRANIAL GERM CELL TUMOURS (icGCT): LESSONS FROM THE UK COHORT OF SIOP GCT96 STUDY

Thankamma Ajithkumar, Henry Mandeville, Fernando Carceller, Milind Ronghe, Tina Foord, Stephen Lowis, Michelle Kwok-Williams, Gabriele Calaminus, Matthew Murray, James Nicholson,

Abstract <h4>BACKGROUND</h4> There are global variations in radiotherapy approaches for icGCT. An understanding of patterns of disease recurrence correlated with radiation techniques and doses is important in standardising and improving the quality of radiotherapy using high-precision techniques. <h4>METHODS AND RESULTS</h4> Data from 20 patients with tumour recurrence after treatment within ... Read more >>

Neuro Oncol (Neuro-oncology)
[2020, 22(Suppl 3):iii340-iii340]

Cited: 0 times

View full text PDF listing >>



Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups.

Soledad Gallego, Yueh-Yun Chi, Gian Luca De Salvo, Minjie Li, Johannes H M Merks, David A Rodeberg, Sheila Terwisscha van Scheltinga, Leo Mascarenhas, Daniel Orbach, Meriel Jenney, Lynn Million, Veronique Minard-Colin, Suzanne Wolden, Ilaria Zanetti, David M Parham, Henry Mandeville, Rajkumar Venkatramani, Gianni Bisogno, Douglas S Hawkins, ,

<h4>Background</h4>Treatment of children and adolescents with alveolar rhabdomyosarcoma (ARMS) and regional nodal involvement (N1) have been approached differently by North American and European cooperative groups. In order to define a better therapeutic strategy, we analyzed two studies conducted between 2005 and 2016 by the European paediatric Soft tissue sarcoma Study ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(3):e28832]

Cited: 0 times

View full text PDF listing >>



The SIOP-Renal Tumour Study Group consensus statement on flank target volume delineation for highly conformal radiotherapy.

Geert O Janssens, Patrick Melchior, Joeri Mul, Daniel Saunders, Stephanie Bolle, Alison L Cameron, Line Claude, Kristin Gurtner, Kees P van de Ven, Martine van Grotel, Semi Harrabi, Yasmin Lassen-Ramshad, Naomi Lavan, Henriette Magelssen, Xavier Muracciole, Tom Boterberg, Henry Mandeville, Jan Godzinski, Norbert Graf, Marry M van den Heuvel-Eibrink, Christian Rübe,

For decades, radiotherapy with two opposing photon beams has been the standard technique used to cover the flank target volume in paediatric patients with renal tumours. Nowadays, many institutes are implementing advanced radiotherapy techniques that spare healthy tissue. To decrease the radiotherapy dose to healthy structures while preserving oncological efficacy, ... Read more >>

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, 4(11):846-852]

Cited: 1 time

View full text PDF listing >>



Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG-RMS2005 study.

Sheila E J Terwisscha van Scheltinga, Marc H W A Wijnen, Hélène Martelli, Timothy Rogers, Henry Mandeville, Mark N Gaze, Keiran McHugh, Nadege Corradini, Daniel Orbach, Meriel Jenney, Anna Kelsey, Julia Chisholm, Soledad Gallego, Heidi Glosli, Andrea Ferrari, Ilaria Zanetti, Gian Luca De Salvo, Veronique Minard-Colin, Giani Bisogno, Max M van Noesel, Hans H M Merks,

Rhabdomyosarcoma of the extremities present with two main challenges: correct evaluation of initial regional nodal involvement and define adequate local treatment.<h4>Methods</h4>Pediatric patients with localized rhabdomyosarcoma of the extremity included in the EpSSG-RMS2005 study between 2005 and 2014 were evaluated for staging, treatment, and survival. The outcome was compared to the ... Read more >>

Cancer Med (Cancer medicine)
[2020, 9(20):7580-7589]

Cited: 0 times

View full text PDF listing >>



Radiological pseudoprogression post-radiotherapy in a child with pineal germ cell tumour.

Inês Alves, Istvan Bodi, Jozef Jarosz, Henry Mandeville, Bassel Zebian, Fernando Carceller,

Little is known about pseudoprogression in brain tumours other than gliomas. A 9-year-old male child with a pineal teratoma/germinoma underwent surgical resection followed by adjuvant chemo-radiotherapy. The magnetic resonance imaging scan 4 months post-radiotherapy showed a contrast-enhancing lesion within the surgical cavity suspicious of recurrence. These radiological findings subsequently resolved ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2020, 67(7):e28407]

Cited: 0 times

View full text PDF listing >>



Estimating brain volume loss after radiation therapy in children treated for posterior fossa tumors (Corpus callosum and whole brain volume changes following radiotherapy in children).

Elwira Szychot, Kiran K. Seunarine, Carlos Andrés Robles, Henry Mandeville, Kshitij Mankad, Christopher Clark, Jaroslaw Peregud-Pogorzelski, Nandita Desouza,

<h4>Background</h4>More than half of pediatric tumors of central nervous system (CNS) primarily originate in the posterior fossa and are conventionally treated with radiation therapy (RT).<h4>Objectives</h4>The objective of this study was to establish whether corpus callosum volumes (CCV) and whole brain volumes (WBV) are correlated and to determine the impact of ... Read more >>

Adv Clin Exp Med (Advances in clinical and experimental medicine : official organ Wroclaw Medical University)
[2020, 29(3):331-337]

Cited: 1 time

View full text PDF listing >>



A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations.

Sally L George, Elisa Izquierdo, James Campbell, Eleni Koutroumanidou, Paula Proszek, Sabri Jamal, Deborah Hughes, Lina Yuan, Lynley V Marshall, Fernando Carceller, Julia C Chisholm, Sucheta Vaidya, Henry Mandeville, Paola Angelini, Ajla Wasti, Tomas Bexelius, Khin Thway, Susanne A Gatz, Matthew Clarke, Bissan Al-Lazikani, Giuseppe Barone, John Anderson, Deborah A Tweddle, David Gonzalez, Brian A Walker, Jack Barton, Sarita Depani, Jessica Eze, Saira W Ahmed, Lucas Moreno, Andrew Pearson, Janet Shipley, Chris Jones, Darren Hargrave, Thomas S Jacques, Michael Hubank, Louis Chesler,

BACKGROUND:For children with cancer, the clinical integration of precision medicine to enable predictive biomarker-based therapeutic stratification is urgently needed. METHODS:We have developed a hybrid-capture next-generation sequencing (NGS) panel, specifically designed to detect genetic alterations in paediatric solid tumours, which gives reliable results from as little as 50 ng of DNA extracted ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2019, 121:224-235]

Cited: 5 times

View full text PDF listing >>



A step and shoot intensity modulated technique for total body irradiation.

Lotte S Fog, Vibeke N Hansen, Flemming Kjær-Kristoffersen, Tim Egholm Berlon, Peter Meidahl Petersen, Henry Mandeville, Lena Specht,

Introduction:Total body irradiation (TBI) is a part of the conditioning regimen for bone marrow transplant.At the Royal Marsden (Sutton, UK) and Rigshospitalet (Copenhagen, Denmark), we introduced a step and shoot IMRT (SS IMRT) technique for TBI. This technique requires no equipment other than that used to deliver other external beam ... Read more >>

Tech Innov Patient Support Radiat Oncol (Technical innovations & patient support in radiation oncology)
[2019, 10:1-7]

Cited: 1 time

View full text PDF listing >>



Managing peritoneal involvement in children and young people with rhabdomyosarcoma: A single-center experience from the United Kingdom.

Nirmalya Roy Moulik, Sucheta Vaidya, Henry Mandeville, Julia C Chisholm,

We describe our experience in managing nine children and adolescents with rhabdomyosarcoma (RMS) and peritoneal involvement. The radiological pattern of peritoneal involvement was diverse from only ascites to solid peritoneal mass/omental caking. Treatment included systemic chemotherapy in all, surgery in three, and radiotherapy in eight. Two patients with presumed nonmalignant ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2019, 66(9):e27805]

Cited: 0 times

View full text PDF listing >>



Post-radiotherapy apparent diffusion coefficient (ADC) in children and young adults with high-grade gliomas and diffuse intrinsic pontine gliomas.

Fernando Carceller, Neil P Jerome, Lucy A Fowkes, Komel Khabra, Andrew Mackinnon, Francisco Bautista, Lynley V Marshall, Sucheta Vaidya, Henry Mandeville, Veronica Morgan, Martin O Leach, Dow-Mu Koh,

<b>Objectives</b>: Diffusion-weighted magnetic resonance imaging (DW-MRI) offers potential to monitor response and predict survival in high-grade gliomas (HGG) and diffuse intrinsic pontine gliomas (DIPG). We hypothesized that post-radiotherapy DW-MRI may provide prognostic imaging biomarkers in children and young adults with these tumors. <b>Methods</b>: Patients aged ≤21 years diagnosed between 2005 and ... Read more >>

Pediatr Hematol Oncol (Pediatric hematology and oncology)
[2019, 36(2):103-112]

Cited: 2 times

View full text PDF listing >>



Psychosocial well-being of long-term survivors of pediatric head-neck rhabdomyosarcoma.

Bas Vaarwerk, Reineke A Schoot, Heleen Maurice-Stam, Olga Slater, Benjamin Hartley, Peerooz Saeed, Eva Gajdosova, Michiel W van den Brekel, Alfons J M Balm, Marinka L F Hol, Stefanie van Jaarsveld, Leontien C M Kremer, Cecile M Ronckers, Henry C Mandeville, Bradley R Pieters, Mark N Gaze, Raquel Davila Fajardo, Simon D Strackee, David Dunaway, Ludi E Smeele, Julia C Chisholm, Huib N Caron, Martha A Grootenhuis, Johannes H M Merks,

<h4>Background</h4>Head and neck rhabdomyosarcoma (HNRMS) survivors are at risk to develop adverse events (AEs). The impact of these AEs on psychosocial well-being is unclear. We aimed to assess psychosocial well-being of HNRMS survivors and examine whether psychosocial outcomes were associated with burden of therapy.<h4>Procedure</h4>Sixty-five HNRMS survivors (median follow-up: 11.5 years), ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2019, 66(2):e27498]

Cited: 1 time

View full text PDF listing >>



Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicentre, open-label, randomised controlled, phase 3 trial.

Gianni Bisogno, Meriel Jenney, Christophe Bergeron, Soledad Gallego Melcón, Andrea Ferrari, Odile Oberlin, Modesto Carli, Michael Stevens, Anna Kelsey, Angela De Paoli, Mark N Gaze, Helene Martelli, Christine Devalck, Johannes H Merks, Myriam Ben-Arush, Heidi Glosli, Julia Chisholm, Daniel Orbach, Veronique Minard-Colin, Gian Luca De Salvo, ,

<h4>Background</h4>Rhabdomyosarcoma is an aggressive tumour that can develop in almost any part of the body. Doxorubicin is an effective drug against rhabdomyosarcoma, but its role in combination with an established multidrug regimen remains controversial. Therefore, we aimed to evaluate the possible benefit of early dose intensification with doxorubicin in patients ... Read more >>

Lancet Oncol (The Lancet. Oncology)
[2018, 19(8):1061-1071]

Cited: 20 times

View full text PDF listing >>



Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

Mara Vinci, Anna Burford, Valeria Molinari, Ketty Kessler, Sergey Popov, Matthew Clarke, Kathryn R Taylor, Helen N Pemberton, Christopher J Lord, Alice Gutteridge, Tim Forshew, Diana Carvalho, Lynley V Marshall, Elizabeth Y Qin, Wendy J Ingram, Andrew S Moore, Ho-Keung Ng, Saoussen Trabelsi, Dorra H'mida-Ben Brahim, Natacha Entz-Werle, Stergios Zacharoulis, Sucheta Vaidya, Henry C Mandeville, Leslie R Bridges, Andrew J Martin, Safa Al-Sarraj, Christopher Chandler, Mariona Sunol, Jaume Mora, Carmen de Torres, Ofelia Cruz, Angel M Carcaboso, Michelle Monje, Alan Mackay, Chris Jones,

The failure to develop effective therapies for pediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to quantitatively assess the extent to which this was present in these tumors through subclonal genomic analyses and to determine whether distinct tumor subpopulations ... Read more >>

Nat Med (Nature medicine)
[2018, 24(8):1204-1215]

Cited: 33 times

View full text PDF listing >>



HGG-23. DRUG SCREENING LINKED TO MOLECULAR PROFILING IDENTIFIES NOVEL DEPENDENCIES IN PATIENT-DERIVED PRIMARY CULTURES OF PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

Alan Mackay, Valeria Molinari, Diana Carvalho, Helen Pemberton, Sara Temelso, Anna Burford, Matthew Clarke, Mariama Fofana, Jessica Boult, Elisa Izquierdo, Kathryn Taylor, Lynn Bjerke, Janat Fazal Salom, Ketty Kessler, Rebecca Rogers, Christopher Chandler, Bassel Zebian, Andrew Martin, Simon Stapleton, Samatha Hettige, Lynley Marshall, Fernando Carceller, Henry Mandeville, Sucheta Vaidya, Leslie Bridges, Safa Al-Sarraj, Jane Pears, Angela Mastronuzzi, Andrea Carai, Francesca del Bufalo, Carmen de Torres, Mariona Sunol, Ofelia Cruz, Jaume Mora, Andrew Moore, Simon Robinson, Christopher Lord, Angel Montero Carcaboso, Maria Vinci, Chris Jones,

Abstract Paediatric high grade glioma and diffuse midline glioma (including DIPG) are comprised of multiple biological and clinical subgroups, the majority of which urgently require novel therapies. Patient-derived in vitro primary cell cultures represent potentially useful tools for mechanistic and preclinical investigation based upon their retention of key features of ... Read more >>

Neuro Oncol (Neuro-oncology)
[2018, 20(Suppl 2):i93-i94]

Cited: 0 times

View full text PDF listing >>



Fusion status in patients with lymph node-positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG).

Soledad Gallego, Ilaria Zanetti, Daniel Orbach, Dominique Ranchère, Janet Shipley, Angelica Zin, Christophe Bergeron, Gian Luca de Salvo, Julia Chisholm, Andrea Ferrari, Meriel Jenney, Henry C Mandeville, Timothy Rogers, Johannes H M Merks, Peter Mudry, Heidi Glosli, Giuseppe Maria Milano, Sima Ferman, Gianni Bisogno, ,

BACKGROUND:Alveolar rhabdomyosarcoma (aRMS) with lymph node involvement (N1 classification) accounts for up to 10% of all cases of RMS. The prognosis is poor, and is comparable to that of distant metastatic disease. In the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) RMS2005 protocol, patients with a histologic diagnosis of ... Read more >>

Cancer (Cancer)
[2018, 124(15):3201-3209]

Cited: 10 times

View full text PDF listing >>



HGG-13. SURVIVAL OUTCOMES OF CHILDREN AND ADOLESCENTS WITH BI-THALAMIC GLIOMAS: THE SOUTH THAMES NEURO-ONCOLOGY UNIT EXPERIENCE

Ajla Wasti, Tineke Boesten, Karen Powell, Lynley Marshall, Sucheta Vaidya, Paola Angelini, Henry Mandeville, Frank Saran, Julia Chisholm, Chris Jones, Chris Chandler, Simon Stapleton, Leslie Bridges, Safa Al-Sarraj, Fernando Carceller,

Abstract <h4>BACKGROUND</h4> Bithalamic gliomas (BG) are rare brain tumours typically with a dismal prognosis, irrespective of histological grading. Limited information is available on survival outcomes for children and adolescents with BG. <h4>METHODS</h4> Review of patients aged ≤18 years with clinico-radiological diagnosis of BG between 1995-2017 at our institution. Clinical, radiological, ... Read more >>

Neuro Oncol (Neuro-oncology)
[2018, 20(Suppl 2):i91-i91]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1153 s