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Author Hennie Lombaard

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Maternal characteristics and pregnancy outcomes of hospitalized pregnant women with SARS-CoV-2 infection in South Africa: An International Network of Obstetric Survey Systems-based cohort study.

Samantha Budhram, Valerie Vannevel, Tanita Botha, Lawrence Chauke, Shastra Bhoora, Gaynor M Balie, Natalie Odell, Hennie Lombaard, Amy Wise, Chrysanthi Georgiou, Nondumiso Ngxola, Emma Wynne, Unati Mbewu, Mfundo Mabenge, Sibusiso Phinzi, Nontsikelelo Gubu-Ntaba, Gareth Goldman, Kay Tunkyi, Sudhir Prithipal, Keshree Naidoo, Santhi Venkatachalam, Terence Moodley, Sean Mould, Mzuvele Hlabisa, Logie Govender, Charlene Maistry, John P Habineza, Priya Israel, Serantha Foolchand, Nomandla V Tsibiyane, Mala Panday, Priya Soma-Pillay, Sumaiya Adam, Felicia Molokoane, Matthew S Mojela, Elizabeth J van Rensburg, Tshililo Mashamba, Mushi Matjila, Sue Fawcus, Ayesha Osman, Mareli Venter, Gregory Petro, Ahminah Fakier, Eduard Langenegger, Catherine A Cluver, Adrie Bekker, Liesl de Waard, Chantal Stewart, Nnabuike C Ngene, Ongombe Lunda, Sylvia N Cebekhulu, Siva Moodley, Mama-Asu Koranteng-Peprah, Emmanuel M C Ati, Salome Maswime, Laura M Yates,

<h4>Objective</h4>To describe risk factors and outcomes of pregnant women infected with SARS-CoV-2 admitted to South African healthcare facilities.<h4>Methods</h4>A population-based cohort study was conducted utilizing an amended International Obstetric Surveillance System protocol. Data on pregnant women with SARS-CoV-2 infection, hospitalized between April 14, 2020, and November 24, 2020, were analyzed.<h4>Results</h4>A total ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, :]

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Deaths Attributed to Respiratory Syncytial Virus in Young Children in High-Mortality Rate Settings: Report from Child Health and Mortality Prevention Surveillance (CHAMPS).

Dianna M Blau, Vicky L Baillie, Toyah Els, Sana Mahtab, Portia Mutevedzi, Adama Mamby Keita, Karen L Kotloff, Ashka Mehta, Samba O Sow, Milagritos D Tapia, Beth A Tippett Barr, Benard O Oluoch, Clayton Onyango, Gunturu Revathi, Jennifer R Verani, Mahlet Abayneh, Nega Assefa, Lola Madrid, Joseph O Oundo, J Anthony G Scott, Quique Bassat, Inacio Mandomando, Antonio Sitoe, Marta Valente, Rosauro Varo, Ima-Abasi Bassey, Carrie Jo Cain, Amara Jambai, Ikechukwu Ogbuanu, Julius Ojulong, Muntasir Alam, Shams El Arifeen, Emily S Gurley, Afruna Rahman, Mustafizur Rahman, Jessica L Waller, Betsy Dewey, Robert F Breiman, Cynthia G Whitney, Shabir A Madhi, ,

<h4>Background</h4>Lower respiratory tract infections are a leading cause of death in young children, but few studies have collected the specimens needed to define the role of specific causes. The Child Health and Mortality Prevention Surveillance (CHAMPS) platform aims to investigate causes of death in children aged <5 years in high-mortality ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2021, 73(Supplement_3):S218-S228]

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Initial findings from a novel population-based child mortality surveillance approach: a descriptive study.

Allan W Taylor, Dianna M Blau, Quique Bassat, Dickens Onyango, Karen L Kotloff, Shams El Arifeen, Inacio Mandomando, Richard Chawana, Vicky L Baillie, Victor Akelo, Milagritos D Tapia, Navit T Salzberg, Adama Mamby Keita, Timothy Morris, Shailesh Nair, Nega Assefa, Anna C Seale, J Anthony G Scott, Reinhard Kaiser, Amara Jambai, Beth A Tippet Barr, Emily S Gurley, Jaume Ordi, Sherif R Zaki, Samba O Sow, Farzana Islam, Afruna Rahman, Scott F Dowell, Jeffrey P Koplan, Pratima L Raghunathan, Shabir A Madhi, Robert F Breiman, ,

<h4>Background</h4>Sub-Saharan Africa and south Asia contributed 81% of 5·9 million under-5 deaths and 77% of 2·6 million stillbirths worldwide in 2015. Vital registration and verbal autopsy data are mainstays for the estimation of leading causes of death, but both are non-specific and focus on a single underlying cause. We aimed ... Read more >>

Lancet Glob Health (The Lancet. Global health)
[2020, 8(7):e909-e919]

Cited: 12 times

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Growth Forms of Gardnerella spp. and Lactobacillus spp. on Vaginal Cells.

Hyunsul Jung, Marthie M Ehlers, Remco P H Peters, Hennie Lombaard, Mathys J Redelinghuys, Johanna E Bezuidenhoudt, Marleen M Kock,

Bacterial vaginosis (BV) is a common vaginal condition in women of reproductive age. During BV development, BV-associated bacteria may form a polymicrobial biofilm, which predispose women to recurrent BV. The aim of the study was to investigate the growth forms of <i>Gardnerella</i> spp. and <i>Lactobacillus</i> spp. and to determine the ... Read more >>

Front Cell Infect Microbiol (Frontiers in cellular and infection microbiology)
[2020, 10:71]

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Odon device for instrumental vaginal deliveries: results of a medical device pilot clinical study.

Javier A Schvartzman, Hugo Krupitzki, Mario Merialdi, Ana Pilar Betrán, Jennifer Requejo, My Huong Nguyen, Effy Vayena, Angel E Fiorillo, Enrique C Gadow, Francisco M Vizcaino, Felicitas von Petery, Victoria Marroquin, María Luisa Cafferata, Agustina Mazzoni, Valerie Vannevel, Robert C Pattinson, A Metin Gülmezoglu, Fernando Althabe, Mercedes Bonet, ,

<h4>Background</h4>A prolonged and complicated second stage of labour is associated with serious perinatal complications. The Odon device is an innovation intended to perform instrumental vaginal delivery presently under development. We present an evaluation of the feasibility and safety of delivery with early prototypes of this device from an early terminated ... Read more >>

Reprod Health (Reproductive health)
[2018, 15(1):45]

Cited: 4 times

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Etiology of bacterial vaginosis and polymicrobial biofilm formation.

Hyun-Sul Jung, Marthie M Ehlers, Hennie Lombaard, Mathys J Redelinghuys, Marleen M Kock,

Microorganisms in nature rarely exist in a planktonic form, but in the form of biofilms. Biofilms have been identified as the cause of many chronic and persistent infections and have been implicated in the etiology of bacterial vaginosis (BV). Bacterial vaginosis is the most common form of vaginal infection in ... Read more >>

Crit Rev Microbiol (Critical reviews in microbiology)
[2017, 43(6):651-667]

Cited: 24 times

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Autologous intrauterine transfusion in a case of anti-U.

Sumaiya Adam, Hennie Lombaard,

<h4>Background</h4>Minor red blood cell antibodies are becoming a more common cause of hemolytic disease of the newborn. Anti-U are a rare alloantibody found almost exclusively in people of black descent. There is limited experience to guide the management of pregnancies complicated by anti-U. Furthermore, there is often no suitable cross-matched ... Read more >>

Transfusion (Transfusion)
[2016, 56(12):3029-3032]

Cited: 2 times

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Discordant monoamniotic twins with Pena-Shokeir phenotype.

Sumaiya Adam, Hennie Lombaard, Careni Spencer,

Pena-Shokeir phenotype is a rare disorder. However, its etiology is incompletely understood. It may be familial or may be due to anoxic-ischemic etiology. Although rare, it can affect one twin in a monoamniotic pregnancy, most likely due to early cord entanglement. ... Read more >>

Clin Case Rep (Clinical case reports)
[2016, 4(10):919-921]

Cited: 1 time

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Evaluating current knowledge of legislation and practice of obstetricians and gynaecologists in the management of fetal remains in South Africa.

Lorraine Du Toit-Prinsloo, Camilla Pickles, Hennie Lombaard,

<h4>Background</h4>In the clinical setting, the main legislative provisions governing the management and 'disposal' of fetal remains in South Africa are the Choice on Termination of Pregnancy Act 92 of 1996 and the Births and Deaths Registration Act 51 of 1992.<h4>Objectives</h4>To determine obstetricians' and gynaecologists' current knowledge of this legislation. Current ... Read more >>

S Afr Med J (South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde)
[2016, 106(4):56]

Cited: 0 times

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Global obstetric medicine: Collaborating towards global progress in maternal health.

Tabassum Firoz, Oier Ateka-Barrutia, Jose Antonio Rojas-Suarez, Chandrika Wijeyaratne, Eliana Castillo, Hennie Lombaard, Laura A Magee,

Globally, the nature of maternal mortality and morbidity is shifting from direct obstetric causes to an increasing proportion of indirect causes due to chronic conditions and ageing of the maternal population. Obstetric medicine can address an important gap in the care of women by broadening its scope to include colleagues, ... Read more >>

Obstet Med (Obstetric medicine)
[2015, 8(3):138-145]

Cited: 4 times

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An audit of the initial resuscitation of severely ill patients presenting with septic incomplete miscarriages at a tertiary hospital in South Africa.

Hennie Lombaard, Sumaiya Adam, Jennifer Makin, Patricia Sebola,

<h4>Background</h4>Septic incomplete miscarriages remain a cause of maternal deaths in South Africa. There was an initial decline in mortality when a strict protocol based approach and the Choice of Termination of Pregnancy Act in South Africa were implemented in this country. However, a recent unpublished audit at the Pretoria Academic ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2015, 15:82]

Cited: 1 time

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Antimicrobial susceptibility patterns of Ureaplasma species and Mycoplasma hominis in pregnant women.

Mathys J Redelinghuys, Marthie M Ehlers, Andries W Dreyer, Hennie A Lombaard, Marleen M Kock,

<h4>Background</h4>Genital mycoplasmas colonise up to 80% of sexually mature women and may invade the amniotic cavity during pregnancy and cause complications. Tetracyclines and fluoroquinolones are contraindicated in pregnancy and erythromycin is often used to treat patients. However, increasing resistance to common antimicrobial agents is widely reported. The purpose of this ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2014, 14:171]

Cited: 29 times

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Comparison of the new Mycofast Revolution assay with a molecular assay for the detection of genital mycoplasmas from clinical specimens.

Mathys J Redelinghuys, Marthie M Ehlers, Andries W Dreyer, Hennie A Lombaard, Marleen M Kock,

<h4>Background</h4>Genital mycoplasmas are opportunistic bacteria that are associated with undesirable gynaecologic and reproductive events. Mycoplasmas are fastidious bacteria with increasing resistance to routine antimicrobials and often fail to grow on conventional culture methods. The commercial Mycofast Revolution assay permits the phenotypic detection and identification of genital mycoplasmas. Antimicrobial susceptibility testing ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2013, 13:453]

Cited: 8 times

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Pilot social feasibility study for the establishment of a public human umbilical cord blood stem cell bank in South Africa.

Madelein Meissner-Roloff, Wendy Young, Isabella Rangaka, Hennie Lombaard, Ames Dhai, Norma Tsotsi, Michael S Pepper,

There is a large unmet need in South Africa for bone marrow transplantation. Umbilical cord blood (UCB) is an important source of stem cells for the treatment of haematological and non-haematological diseases. Access to the two existing private umbilical cord blood stem cell banks (UCB SCBs) in South Africa is ... Read more >>

Stem Cell Rev Rep (Stem cell reviews and reports)
[2012, 8(4):1066-1075]

Cited: 1 time

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Randomised trial of cervical cerclage, with and without occlusion, for the prevention of preterm birth in women suspected for cervical insufficiency.

N Brix, N J Secher, C D McCormack, R B Helmig, M Hein, T Weber, S Mittal, W Kurdi, M Palacio, T B Henriksen, ,

<h4>Objective</h4>To evaluate the effect of cerclage, with and without cervical occlusion.<h4>Design</h4>Multicentre, stratified, randomised controlled trial.<h4>Setting</h4>Hospital-based multicentre study with 18 tertiary centres from nine countries.<h4>Population</h4>Women with a history of cervical insufficiency (prophylactic trial) and women with a short cervix (therapeutic trial) were recruited from August 2006 to August 2011.<h4>Methods</h4>A centralised telephone ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2013, 120(5):613-620]

Cited: 8 times

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P37. Non-invasive haemodynamic monitoring using transthoracic echocardiography in pregnancy: Validation against cardiac catheterisation.

Jerome Cornette, Hennie Lombaard, Jolien Roos, Wim Hop, Robert C Pattinson,

Pregnancy Hypertens (Pregnancy hypertension)
[2011, 1(3-4):289-290]

Cited: 1 time

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Managing acute collapse in pregnant women.

Hennie Lombaard, Priya Soma-Pillay, El-Marie Farrell,

The most important causes of acute collapse in pregnancy are pulmonary embolism, amniotic fluid embolism, acute coronary syndrome, thrombosed mechanical prosthetic heart valves, acute aortic dissection, cerebrovascular incidents and anaesthetic complications like failed intubation, anaphylaxis, and problems relating to regional or local anaesthetic agents. The management is based on supporting ... Read more >>

Best Pract Res Clin Obstet Gynaecol (Best practice & research. Clinical obstetrics & gynaecology)
[2009, 23(3):339-355]

Cited: 4 times

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Common errors and remedies in managing postpartum haemorrhage.

Hennie Lombaard, Robert C Pattinson,

Postpartum haemorrhage (PPH) is a major contributor to maternal morbidity and mortality. By only examining mortality, the full extent of the problem is not revealed and also it is important to evaluate the avoidable factors. This will identify the areas that need attention. The common errors include not treating anaemia ... Read more >>

Best Pract Res Clin Obstet Gynaecol (Best practice & research. Clinical obstetrics & gynaecology)
[2009, 23(3):317-326]

Cited: 11 times

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Underlying medical conditions.

Hennie Lombaard, Robert C Pattinson,

More than half of maternal deaths in the UK are due to pre-existing medical conditions, and medical emergencies often mimic acute obstetric conditions. An acute flare of systemic lupus erythaematosus, a thyroid storm or a phaeochromocytoma have many of the signs and symptoms of imminent eclampsia. Similarly, severe postpartum haemorrhage ... Read more >>

Best Pract Res Clin Obstet Gynaecol (Best practice & research. Clinical obstetrics & gynaecology)
[2008, 22(5):847-864]

Cited: 5 times

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The obstetrician's view: ethical and societal implications of non-invasive prenatal diagnosis.

Richard P Smith, Hennie Lombaard, Peter W Soothill,

We believe non-invasive prenatal diagnosis is about to have a massive impact on the way fetal medicine is practised. There will be many great advantages and improvements, but the technology also has the potential to be used for non-medical reasons such as sex selection and paternity testing. We discuss some ... Read more >>

Prenat Diagn (Prenatal diagnosis)
[2006, 26(7):631-634]

Cited: 13 times

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Evaluation of a strict protocol approach in managing women with severe disease due to hypertension in pregnancy: a before and after study.

Hennie Lombaard, Robert C Pattinson, Fèbè Backer, Peter Macdonald,

<h4>Background</h4>To evaluate whether the introduction of a strict protocol based on the systemic evaluation of critically ill pregnant women with complications of hypertension affected the outcome of those women.<h4>Method</h4><h4>Study group</h4>Indigent South African women managed in the tertiary hospitals of the Pretoria Academic Complex. Since 1997 a standard definition of women ... Read more >>

Reprod Health (Reproductive health)
[2005, 2:7]

Cited: 2 times

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