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Author Heng Wang

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Narcissistic self-sorting in anion-coordination-driven assemblies.

Xiaotong Zhao, Heng Wang, Boyang Li, Bo Zheng, Dong Yang, Wenhua Xu, Xiaopeng Li, Xiao-Juan Yang, Biao Wu,

Three tris-bis(urea) ligands with triphenylamine-based C<sub>3</sub>-symmetric spacers were synthesized, which assembled with sulfate or phosphate to form anionic A<sub>3</sub>L<sub>2</sub> pinwheel helices (A = anion and L = ligand) and A<sub>4</sub>L<sub>4</sub> tetrahedra, respectively. Interestingly, narcissistic self-sorting was observed in both structures from the mixture of the ligands, wherein each assembly contains ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(49):6078-6081]

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MicroRNA-378 regulates adipogenic differentiation in bovine intramuscular preadipocytes by targeting CaMKK2.

Dongwei Li, Heng Wang, Yongmin Li, Changqing Qu, Yunhai Zhang, Hongyu Liu, Xiaorong Zhang,

Intramuscular fat, as one of the most important palatability attribute of beef carcase, is the primary determinant of beef quality. The research of adipogenesis mechanism would provide new insight into intramuscular fatty deposition. Here, the role of microRNA-378 was investigated during bovine adipogenic differentiation. It was revealed that miR-378 expression ... Read more >>

Adipocyte (Adipocyte)
[2021, 10(1):483-492]

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Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model.

Peili Wang, Jiaxiang Zhang, Yanfei Chen, Haoran Zhong, Heng Wang, Jianji Li, Guoqiang Zhu, Pengpeng Xia, Luying Cui, Jun Li, Junsheng Dong, Qingqing Gao, Xia Meng,

Colibactin is synthesized by a 54-kb genomic island, leads to toxicity in eukaryotic cells, and plays a vital role in many diseases, including neonatal sepsis and meningitis. Avian pathogenic <i>Escherichia coli</i> (APEC) is speculated to be an armory of extraintestinal pathogenic <i>Escherichia coli</i> and can be a potential zoonotic bacterium ... Read more >>

Virulence (Virulence)
[2021, 12(1):2382-2399]

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A Hydrogen-Bonded Ravel Assembled by Anion Coordination.

Xiaotong Zhao, Heng Wang, Boyang Li, Wenyao Zhang, Xiaopeng Li, Wei Zhao, Christoph Janiak, Andrew W Heard, Xiao-Juan Yang, Biao Wu,

Anion-coordination-driven assembly (ACDA) is showing increasing power in the construction of anionic supramolecular architectures. Herein, by expanding the anion centers from oxoanion (phosphate or sulfate) to organic tris-carboxylates, an Archimedean solid (truncated tetrahedron) and a highly entangled, double-walled tetrahedron featuring a ravel topology have been assembled with tris-bis(urea) ligands. The ... Read more >>

Angew Chem Int Ed Engl (Angewandte Chemie (International ed. in English))
[2021, :]

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Advanced glycation end-products (AGEs) are lower in prostate tumor tissue and inversely related to proportion of West African ancestry.

Morgan L Zenner, Yves B Helou, Ryan J Deaton, Maria Sverdlov, Heng Wang, Andre Kajdacsy-Balla, Virgilia Macias, Cindy Voisine, Marcus Murray, Sarki A Abdulkadir, Adam B Murphy, Larisa Nonn,

The metabolism of normal prostate relies on glycolysis, with prostate cancer having reduced glycolysis and increased aerobic metabolism. Advanced glycation end products (AGEs) accumulate in tissues as a result of age and glycolytic rate. Differential AGE levels were recently observed in prostate cancer tissues. Herein we sought to quantify AGEs ... Read more >>

Prostate (The Prostate)
[2021, :]

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The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β.

Qi Gao, Yunlong Yang, Weipeng Quan, Jiachen Zheng, Yizhuo Luo, Heng Wang, Xiongnan Chen, Zhao Huang, Xiaojun Chen, Runda Xu, Guihong Zhang, Lang Gong,

African swine fever virus (ASFV) poses serious threats to the swine industry. The mortality rate of African swine fever (ASF) is 100%, and there is no effective vaccine currently available. Complex immune escape strategies of ASFV are crucial factors affecting immune prevention and vaccine development. CD2v and MGF360-505R genes have ... Read more >>

Vaccines (Basel) (Vaccines)
[2021, 9(11):]

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The microRNA-381(miR-381)/Spindlin1(SPIN1) axis contributes to cell proliferation and invasion of colorectal cancer cells by regulating the Wnt/β-catenin pathway.

Ling Zhou, Heng Wang, Zhi Fang, Min Zhong, Yan He, Jianping Zou, Shanshan Huang, Junhe Li, Xiaojun Xiang, Ziling Fang,

Our study aimed to investigate the clinical significance and biological functions of Spindlin1 (SPIN1) in colorectal cancer (CRC) tumorigenesis and progression, as well as the mechanism underlying its upregulation. The expression of SPIN1 was detected by immunohistochemistry and western blotting assays. Bioinformatics prediction and dual-luciferase reporter assays were used to ... Read more >>

Bioengineered (Bioengineered)
[2021, :]

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CircRNA circ_0000554 promotes ovarian cancer invasion and proliferation by regulating miR-567.

Hui Wang, Xuezhong Zhang, Lujun Qiao, Heng Wang,

Circular RNAs (circRNAs) indicated potential modulating effects in tumor development. However, the specific role of circ_0000554 in ovarian tumor remains unknown. We found that circ_0000554 was overexpressed in ovarian tumor specimens and cells. Forced expression of circ_0000554 promoted cell growth, invasion, and epithelial to mesenchymal transition (EMT). We illustrated that ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, :]

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Extracting epsilon-near-zero wavelength of ultrathin plasmonic film.

Xinhai Dai, Heng Wang, Lixun Sun, Chao Meng, Shuang Li, Wending Zhang, Ting Mei,

Strong optical nonlinearities of plasmonic thin films exist at their epsilon-near-zero (ENZ) wavelengths, which are essential to be acquired first for the design and fabrication of ENZ photonic devices. However, it has been challenging to obtain the ENZ wavelength precisely when the film thickness is reduced to tens of nanometers ... Read more >>

Appl Opt (Applied optics)
[2021, 60(31):9774-9779]

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Sub-Gbps Key Rate Four-State Continuous-Variable Quantum Key Distribution within Metropolitan Area

Heng Wang, Yang Li, Yaodi Pi, Yan Pan, Yun Shao, Li Ma, Jie Yang, Yichen Zhang, Wei Huang, Bingjie Xu,

Continuous-variable quantum key distribution (CVQKD) has potential advantages of high secret key rate, which is very suitable for high-speed metropolitan network application. However, the reported highest secret key rates of the CVQKD systems up to now are limited in a few Mbps. Here, we address the fundamental experimental problems and ... Read more >>

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Enhanced photosynthetic nitrogen use efficiency and increased nitrogen allocation to photosynthetic machinery under cotton domestication.

Zhang-Ying Lei, Heng Wang, Ian J Wright, Xin-Guang Zhu, Ülo Niinemets, Zi-Liang Li, Dong-Sheng Sun, Ning Dong, Wang-Feng Zhang, Zhong-Li Zhou, Fang Liu, Ya-Li Zhang,

Domestication involves dramatic phenotypic and physiological diversifications due to successive selection by breeders toward high yield and quality. Although photosynthetic nitrogen use efficiency (PNUE) is a major trait for understanding leaf nitrogen economy, it is unclear whether PNUE of cotton has been improved under domestication. Here, we investigated the effect ... Read more >>

Photosynth Res (Photosynthesis research)
[2021, 150(1-3):239-250]

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Progesterone Inhibits LPS-Induced Oxidative Stress Through Nrf2/Keap1 Pathway in Bovine Endometrial Epithelial Cells

Luying Cui, Qi Zhang, Jiaqi Zhang, Heng Wang, Junsheng Dong, Jun Li, Chen Qian, Jianji Li,

<h4>Background: </h4> Postpartum uterine infection can lead to endometrial inflammation and oxidative damage. Progesterone makes the animal more susceptible to uterine infection. Progesterone has been proved to play an anti-inflammatory role in inhibiting uterine innate immunity, and to reduce tissue oxidative damage. But the effect of progesterone on the oxidative ... Read more >>

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Humidity-Sensitive PMMA Fiber Bragg Grating Sensor Probe for Soil Temperature and Moisture Measurement Based on Its Intrinsic Water Affinity.

Heng Wang, Shixin Gao, Xiaoyu Yue, Xin Cheng, Qi Liu, Rui Min, Hang Qu, Xuehao Hu,

Soil moisture measurement is very important for soil system monitoring. Compared to the traditional thermo-gravimetric technique, which is time-consuming and can be only performed in labs, the optic-fiber technique has unique advantages, such as small size, remote application in fields, fast response time and immunity to electromagnetic fields. In this ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2021, 21(21):]

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Unpacking the myth between increased government initiatives and reduced selling of dead live stocks in China: An approach towards exploring hidden danger of zoonotic diseases.

Ruishi Si, Xueqian Zhang, Yumeng Yao, Shuxia Zhang, Heng Wang,

Prohibiting the unsafe sale of livestock that have died in production and harmlessly disposing of them are key measures to control and prevent outbreaks of zoonotic diseases and exert a great significance for maintaining meat-derived food and public health safety. However, under the strict implementation of governmental initiatives, some farmers ... Read more >>

One Health (One health (Amsterdam, Netherlands))
[2021, 13:100344]

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ClpV1 in avian pathogenic Escherichia coli is a crucial virulence factor contributing to meningitis in a mouse model in vivo.

Haoran Zhong, Peili Wang, Yanfei Chen, Heng Wang, Jun Li, Jianji Li, Guoqiang Zhu, Luying Cui, Xia Meng,

Meningitis associated with avian pathogenic Escherichia coli (APEC) is an infectious disease of poultry that has gained significant attention because of its potential to infect humans. APEC can utilize two type Ⅵ secretion systems (T6SSs) to efficiently transport toxin effectors into hosts. ClpV1 is one of the core components of ... Read more >>

Vet Microbiol (Veterinary microbiology)
[2021, 263:109273]

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Altered metabolic state impedes limb regeneration in salamanders.

Zhe-Lun Peng, Bin-Xu Yin, Rui-Min Ren, Yin-Long Liao, Hao Cai, Heng Wang,

Salamanders are unique among tetrapods in their ability to regenerate their limbs throughout life. Like other poikilothermic amphibians, salamanders also show a remarkable capacity to survive long periods of starvation. Whether the physiological reserves necessary for tissue regeneration are preserved or sacrificed in starved salamanders is unknown. In the current ... Read more >>

Zool Res (Zoological research)
[2021, 42(6):772-782]

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LINC00265 promotes the viability, proliferation, and migration of bladder cancer cells via the miR-4677-3p/FGF6 axis.

Yunlai Zhi, Fanghu Sun, Chengkuan Cai, Haitao Li, Kunpeng Wang, Jinyu Sun, Tian He, Zhengshuai Ji, Zhaofei Liu, Heng Wang, Ruifei Cheng,

<h4>Background</h4>Bladder cancer (BCa) is a common genitourinary malignancy with higher incidence in males. Long intergenic non-protein coding RNA 265 (LINC00265) is identified as an oncogene in many malignancies, while its role in BCa development remains unknown.<h4>Purpose</h4>To explore the functions and mechanism of LINC00265 in BCa.<h4>Research design</h4>Reverse transcription quantitative polymerase chain ... Read more >>

Hum Exp Toxicol (Human & experimental toxicology)
[2021, :9603271211043479]

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Clostridium butyricum Supplement Can Ameliorate the Intestinal Barrier Roles in Broiler Chickens Experimentally Infected With Clostridium perfringens.

Xiao Xu, Shunli Yang, Joshua Seun Olajide, Zigang Qu, Zhenxing Gong, Jing Wang, Yanbing Zhang, Heng Wang, Ling Xiong, Kun Zhang, Enmin Zhou, Jianping Cai,

Necrotic enteritis (NE), caused by <i>Clostridium perfringens</i>, is an economically important disease in the broiler. Among normal flora in the broiler intestinal region, <i>Clostridium butyricum</i> has been identified as a probiotic agent that reduces the susceptibility of broilers to <i>C. perfringens</i>. However, the effects of <i>C. butyricum</i> supplement on broiler ... Read more >>

Front Physiol (Frontiers in physiology)
[2021, 12:737481]

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Systemic Inflammation Status Relates to Anti-Inflammatory Drug Benefit and Survival in Rectal Cancer.

Xue Cao, Xiaolin Wang, Heng Wang, Gaopo Xu, Huichuan Yu,

<h4>Background</h4>Systemic inflammation status has been recognized as a sensitive marker associated with survival in cancers and anti-inflammatory treatment outcomes in inflammation-derived diseases. This study aimed to investigate the role of systemic inflammation status as a predictive marker for survival and anti-inflammatory treatment benefit in rectal cancer patients.<h4>Methods</h4>A total of 475 ... Read more >>

J Surg Res (The Journal of surgical research)
[2021, 269:249-259]

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Long non‑coding RNA AL355711 promotes smooth muscle cell migration through the ABCG1/MMP3 pathway.

Chun-Min Kang, Wei-Kang Li, Ke-Wei Yu, Xue-Heng Li, Rui-Ying Huang, Pei-Feng Ke, Xing Jin, Shun-Wang Cao, Ying-Shi Yuan, Heng Wang, Jun Yan, Wei-Ye Chen, Xian-Zhang Huang, Jing-Jing Zhao,

Atherosclerosis and related cardiovascular diseases pose severe threats to human health worldwide. There is evidence to suggest that at least 50% of foam cells in atheromas are derived from vascular smooth muscle cells (VSMCs); the first step in this process involves migration to human atherosclerotic lesions. Long non‑coding RNAs (lncRNAs) ... Read more >>

Int J Mol Med (International journal of molecular medicine)
[2021, 48(6):]

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Improving Fast and Safe Transfer of Lithium Ions in Solid-State Lithium Batteries by Porosity and Channel Structure of Polymer Electrolyte.

Libo Li, Yuhang Shan, Furi Wang, Xiaochuan Chen, Yangmingyue Zhao, Da Zhou, Heng Wang, Wenjun Cui,

Solid-state lithium batteries using solid polymer electrolytes can improve the safety and energy density of batteries. Smoother lithium-ion channels are necessary for solid polymer electrolytes with high ionic conductivity. The porosity and channel structure of the polymer film affect the transfer of lithium ions. However, their controllable synthesis remains a ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, :]

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Regulating Te Vacancies through Dopant Balancing via Excess Ag Enables Rebounding Power Factor and High Thermoelectric Performance in p‐Type PbTe (Adv. Sci. 20/2021)

Hanhwi Jang, Jong Ho Park, Ho Seong Lee, Byungki Ryu, Su‐Dong Park, Hyeon‐Ah Ju, Sang‐Hyeok Yang, Young‐Min Kim, Woo Hyun Nam, Heng Wang, James Male, Gerald Jeffrey Snyder, Minjoon Kim, Yeon Sik Jung, Min‐Wook Oh,

Defect Engineering In article number 2100895, Yeon Sik Jung, Min‐Wook Oh, and co‐workers demonstrate the underlying defect chemistry on the rebounding power factor of an Na and Ag co‐doped PbTe. Excess Ag doping is proven to be effective to be the Te vacancy scavenger by forming interstitial Ag clusters, which ... Read more >>

(Advanced Science)
[2021, 8(20):]

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Evidence-Based Research Strategy of Traditional Chinese Medicine for Amyotrophic Lateral Sclerosis.

Hao Pan, Heng Wang, Yanlin Tao, Jinfeng Yuan, Sanbin Xu, Jianli Ni, Meiqin Huang, Xiaojun Wu, Te Liu,

Among adult-onset motor neuron diseases, amyotrophic lateral sclerosis (ALS) is the most common. ALS involves the increasing loss of lower and upper motor neurons. Within a few years of onset, ALS causes patient death via progressive paralysis of respiratory muscles. However, the current drugs used to treat ALS, riluzole, edaravone, ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2021, 2021:3402753]

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Health-Related Quality of Life and Fatigue in Children and Adults with Pyruvate Kinase Deficiency.

Hanny Al-Samkari, Eduard J van Beers, D Holmes Morton, Stefan Eber, Satheesh Chonat, Kevin H M Kuo, Nina Kollmar, Heng Wang, Vicky Breakey, Sujit Sheth, Mukta Sharma, Peter W Forbes, Robert Klaassen, Rachael F Grace,

Pyruvate kinase deficiency (PKD) is the most common cause of congenital non-spherocytic hemolytic anemia. Although recognition of the disease spectrum has recently expanded, data describing its impact on health-related quality of life (HRQoL) are limited. In this prospective international cohort of 254 patients (131 adults and 123 children) with PKD, ... Read more >>

Blood Adv (Blood advances)
[2021, :]

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A 3-Gene-Based Diagnostic Signature in Alzheimer's Disease.

Huimin Wang, Yanqiu Zhang, Chengyao Zheng, Songqi Yang, Xiuju Chen, Heng Wang, Sheng Gao,

<h4>Background</h4>Alzheimer's disease (AD) is a chronic neurodegenerative disease. In this study, potential diagnostic biomarkers were identified for AD.<h4>Methods</h4>All AD samples and healthy samples were collected from 2 datasets in the GEO database, in which differentially expressed genes (DEGs) were analyzed by using the limma package of R language. GO and ... Read more >>

Eur Neurol (European neurology)
[2021, :1-8]

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