Full Text Journal Articles by
Author Helmut Neumann

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Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1215-1216]

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Evaluation of novel LCI CAD EYE system for real time detection of colon polyps.

Helmut Neumann, Andreas Kreft, Visvakanth Sivanathan, Fareed Rahman, Peter R Galle,

<h4>Background</h4>Linked color imaging (LCI) has been shown to be effective in multiple randomized controlled trials for enhanced colorectal polyp detection. Recently, artificial intelligence (AI) with deep learning through convolutional neural networks has dramatically improved and is increasingly recognized as a promising new technique for enhancing colorectal polyp detection.<h4>Aim</h4>This study aims ... Read more >>

PLoS One (PloS one)
[2021, 16(8):e0255955]

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Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

<h4>Background</h4>Irritable bowel syndrome (IBS) patients often experience meal-associated symptoms. However, the underlying mechanisms are unclear.<h4>Aim</h4>To determine small intestinal mechanisms of lipid-induced symptoms and rectal hypersensitivity in IBS METHODS: We recruited 26 IBS patients (12 IBS-C, 14 IBS-D) and 15 healthy volunteers (HV). In vivo permeability was assessed using saccharide excretion ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1179-1192]

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Artificial intelligence in gastrointestinal endoscopy for inflammatory bowel disease: a systematic review and new horizons.

Gian Eugenio Tontini, Alessandro Rimondi, Marta Vernero, Helmut Neumann, Maurizio Vecchi, Cristina Bezzio, Flaminia Cavallaro,

<h4>Introduction</h4>Since the advent of artificial intelligence (AI) in clinical studies, luminal gastrointestinal endoscopy has made great progress, especially in the detection and characterization of neoplastic and preneoplastic lesions. Several studies have recently shown the potential of AI-driven endoscopy for the investigation of inflammatory bowel disease (IBD). This systematic review provides ... Read more >>

Therap Adv Gastroenterol (Therapeutic advances in gastroenterology)
[2021, 14:17562848211017730]

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Near-focus narrow-band imaging classification of villous atrophy in suspected celiac disease: development and international validation.

Shraddha Gulati, Andrew Emmanuel, Mark Ong, Polychronis Pavlidis, Mehul Patel, Tareq El-Menabawey, Zuzana Vackova, Patrick Dubois, Alberto Murino, Jan Martinek, Amrita Sethi, Helmut Neumann, Amyn Haji, Bu'Hussain Hayee,

<h4>Background and aims</h4>There are no agreed-on endoscopic signs for the diagnosis of villous atrophy (VA) in celiac disease (CD), necessitating biopsy sampling for diagnosis. Here we evaluated the role of near-focus narrow-band imaging (NF-NBI) for the assessment of villous architecture in suspected CD with the development and further validation of ... Read more >>

Gastrointest Endosc (Gastrointestinal endoscopy)
[2021, :]

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Zenker's peroral endoscopic myotomy (Z-POEM) for recurrent Zenker diverticulum: not so fast!

Sauid Ishaq, Keith Siau, Toshio Kuwai, Chris J Mulder, Helmut Neumann,

Endoscopy (Endoscopy)
[2021, 53(7):767]

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Evaluation of a novel colonoscope offering flexibility adjuster - a retrospective observational study.

Christian Gerges, Helmut Neumann, Sauid Ishaq, Visvakanth Sivanathan, Peter R Galle, Horst Neuhaus, Helmut Neumann,

<h4>Background</h4>Although colonoscopy is the gold standard for colorectal cancer screening, colonic looping may make complete colonoscopy challenging. Commonly available stiffening device colonoscopy has been described as helpful but not effective enough to prevent looping. In this context the effect on cecal intubation time and rate was described differently in various ... Read more >>

Therap Adv Gastroenterol (Therapeutic advances in gastroenterology)
[2021, 14:17562848211013494]

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PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study.

Federica Branchi, Rolf Klingenberg-Noftz, Kristina Friedrich, Nataly Bürgel, Severin Daum, Juliane Buchkremer, Elena Sonnenberg, Michael Schumann, Christoph Treese, Hanno Tröger, Donata Lissner, Hans-Jörg Epple, Britta Siegmund, Andrea Stroux, Andreas Adler, Winfried Veltzke-Schlieker, Daniel Autenrieth, Silke Leonhardt, Andreas Fischer, Christian Jürgensen, Ulrich-Frank Pape, Bertram Wiedenmann, Oliver Möschler, Maximilian Schreiner, Mathias Z Strowski, Volkmar Hempel, Yvonne Huber, Helmut Neumann, Christian Bojarski,

<h4>Background</h4>A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding. The aim of this pilot study was to evaluate the feasibility, safety, efficacy and indication profiles of PuraStat in a clinical setting.<h4>Methods</h4>In this prospective observational multicentre pilot study, patients with acute ... Read more >>

Surg Endosc (Surgical endoscopy)
[2021, :]

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Panintestinal capsule endoscopy in patients with celiac disease.

Friedrich Foerster, Helmut Neumann,

<h4>Introduction</h4>Capsule endoscopy has proven its utility in diagnosing villous atrophy and lymphoma in patients with celiac disease. Recently, a novel capsule endoscopy system was introduced which enables the examination of the small and large bowel. So far, it has not been evaluated in patients with celiac disease.<h4>Objective</h4>The primary objective of ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2021, :]

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A multicenter, prospective, inpatient feasibility study to evaluate the use of an intra-colonoscopy cleansing device to optimize colon preparation in hospitalized patients: the REDUCE study.

Helmut Neumann, Melissa Latorre, Tim Zimmerman, Gabriel Lang, Jason Samarasena, Seth Gross, Bhaumik Brahmbhatt, Haleh Pazwash, Vladimir Kushnir,

<h4>Background</h4>High quality bowel preparation prior to colonoscopy can be difficult to achieve in the inpatient setting. Hospitalized patients are at risk for extended hospital stays and low diagnostic yield due to inadequate bowel preparation. The Pure-Vu System is a novel device intended to fit over existing colonoscopes to improve intra-colonoscopy ... Read more >>

BMC Gastroenterol (BMC gastroenterology)
[2021, 21(1):232]

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Dynamic microangiography of the gastrointestinal mucosa using magnifying Blue Light Imaging.

Shunsuke Yamamoto, Helmut Neumann,

Endoscopy (Endoscopy)
[2021, :]

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Revising the European Society of Gastrointestinal Endoscopy (ESGE) research priorities: a research progress update.

Pradeep Bhandari, Gaius Longcroft-Wheaton, Diogo Libanio, Pedro Pimentel-Nunes, Eduardo Albeniz, Mathieu Pioche, Reena Sidhu, Cristiano Spada, Andrea Anderloni, Alessandro Repici, Rehan Haidry, Marc Barthet, Helmut Neumann, Giulio Antonelli, Alberto Testoni, Thierry Ponchon, Peter D Siersema, Lorenzo Fuccio, Cesare Hassan, Mario Dinis-Ribeiro,

<h4>Background</h4>One of the aims of the European Society of Gastrointestinal Endoscopy (ESGE) is to encourage high quality endoscopic research at a European level. In 2016, the ESGE research committee published a set of research priorities. As endoscopic research is flourishing, we aimed to review the literature and determine whether endoscopic ... Read more >>

Endoscopy (Endoscopy)
[2021, 53(5):535-554]

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Artificial intelligence in colonoscopy - Now on the market. What's next?

Yuichi Mori, Helmut Neumann, Masashi Misawa, Shin-Ei Kudo, Michael Bretthauer,

Adoption of artificial intelligence (AI) in clinical medicine is revolutionizing daily practice. In the field of colonoscopy, major endoscopy manufacturers have already launched their own AI products on the market with regulatory approval in Europe and Asia. This commercialization is strongly supported by positive evidence that has been recently established ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2021, 36(1):7-11]

Cited: 3 times

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Performance of a new integrated computer-assisted system (CADe/CADx) for detection and characterization of colorectal neoplasia.

Jochen Weigt, Alessandro Repici, Giulio Antonelli, Ahmed Afifi, Leon Kliegis, Loredana Correale, Cesare Hassan, Helmut Neumann,

<h4>Background</h4> Use of artificial intelligence may increase detection of colorectal neoplasia at colonoscopy by improving lesion recognition (CADe) and reduce pathology costs by improving optical diagnosis (CADx).<h4>Methods</h4> A multicenter library of ≥ 200 000 images from 1572 polyps was used to train a combined CADe/CADx system. System testing was performed on two independent image ... Read more >>

Endoscopy (Endoscopy)
[2021, :]

Cited: 1 time

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Artificial intelligence: Thinking outside the box.

Gian Eugenio Tontini, Helmut Neumann,

Artificial intelligence (AI) for luminal gastrointestinal endoscopy is rapidly evolving. To date, most applications have focused on colon polyp detection and characterization. However, the potential of AI to revolutionize our current practice in endoscopy is much more broadly positioned. In this review article, the Authors provide new ideas on how ... Read more >>

Best Pract Res Clin Gastroenterol (Best practice & research. Clinical gastroenterology)
[2021, 52-53:101720]

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Long-term success of flexible endoscopic septal division with the stag beetle knife for Zenker's diverticulum: a tertiary center study.

Sauid Ishaq, Keith Siau, Minhong Lee, Haleema Sultan, Shalmani H Mohaghegh, Toshio Kuwai, Chris J Mulder, Helmut Neumann,

<h4>Objectives</h4>Flexible endoscopic septum division is an established treatment for Zenker's diverticulum (ZD); however, long-term outcome data are lacking. We aimed to evaluate the long-term efficacy of flexible endoscopic septal division (FESD) using the stag beetle knife for ZD and identify predictors of symptom recurrence.<h4>Methods</h4>Patients undergoing the procedure between 2013 and ... Read more >>

Dis Esophagus (Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus)
[2020, 33(11):]

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Water-assisted colonoscopy: an international modified Delphi review on definitions and practice recommendations.

Sergio Cadoni, Sauid Ishaq, Cesare Hassan, Přemysl Falt, Lorenzo Fuccio, Keith Siau, Joseph W Leung, John Anderson, Kenneth F Binmoeller, Franco Radaelli, Matt D Rutter, Shinya Sugimoto, Humayun Muhammad, Pradeep Bhandari, Peter V Draganov, Piet de Groen, Andrew Y Wang, Andrew W Yen, Chris Hamerski, Henrik Thorlacius, Helmut Neumann, Francisco Ramirez, Chris J J Mulder, Eduardo Albéniz, Arnaldo Amato, Makoto Arai, Adrian Bak, Maximilien Barret, Putut Bayupurnama, Ramsey Cheung, Hey-Long Ching, Hartley Cohen, Sunil Dolwani, Shai Friedland, Hideaki Harada, Yu-Hsi Hsieh, Bu Hayee, Toshio Kuwai, Vicente Lorenzo-Zúñiga, Mauro Liggi, Takeshi Mizukami, Donatella Mura, David Nylander, Snorri Olafsson, Silvia Paggi, Yanglin Pan, Adolfo Parra-Blanco, Rupert Ransford, Joaquìn Rodriguez-Sanchez, Hakan Senturk, Noriko Suzuki, Chih-Wei Tseng, Hugo Uchima, Noriya Uedo, Felix W Leung,

<h4>Background and aims</h4>Since 2008, a plethora of research studies has compared the efficacy of water-assisted (aided) colonoscopy (WAC) and underwater resection (UWR) of colorectal lesions with standard colonoscopy. We reviewed and graded the research evidence with potential clinical application. We conducted a modified Delphi consensus among experienced colonoscopists on definitions ... Read more >>

Gastrointest Endosc (Gastrointestinal endoscopy)
[2021, 93(6):1411-1420.e18]

Cited: 1 time

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Real-time unblinding for validation of a new CADe tool for colorectal polyp detection.

Pieter Sinonquel, Tom Eelbode, Cesare Hassan, Giulio Antonelli, Federica Filosofi, Helmut Neumann, Ingrid Demedts, Philip Roelandt, Frederik Maes, Raf Bisschops,

Gut (Gut)
[2021, 70(4):641-643]

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Axis-keeping shortening technique for colonic intubation.

Shunsuke Yamamoto, Yasushi Sano, Nima Mottacki, Helmut Neumann,

VideoGIE (VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy)
[2020, 5(12):630-633]

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Curriculum for optical diagnosis training in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

Evelien Dekker, Britt B S L Houwen, Ignasi Puig, Marco Bustamante-Balén, Emmanuel Coron, Daniela E Dobru, Roman Kuvaev, Helmut Neumann, Gavin Johnson, Pedro Pimentel-Nunes, David S Sanders, Mario Dinis-Ribeiro, Marianna Arvanitakis, Thierry Ponchon, James E East, Raf Bisschops,

Endoscopy (Endoscopy)
[2020, 52(10):C10]

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Curriculum for optical diagnosis training in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

Evelien Dekker, Britt B S L Houwen, Ignasi Puig, Marco Bustamante-Balén, Emmanuel Coron, Daniela E Dobru, Roman Kuvaev, Helmut Neumann, Gavin Johnson, Pedro Pimentel-Nunes, David S Sanders, Mario Dinis-Ribeiro, Marianna Arvanitakis, Thierry Ponchon, James E East, Raf Bisschops,

This manuscript represents an official Position Statement of the European Society of Gastrointestinal Endoscopy (ESGE) aiming to guide general gastroenterologists to develop and maintain skills in optical diagnosis during endoscopy. In general, this requires additional training beyond the core curriculum currently provided in each country. In this context, ESGE have ... Read more >>

Endoscopy (Endoscopy)
[2020, 52(10):899-923]

Cited: 3 times

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Reopening Endoscopy after the COVID-19 Outbreak: Indications from a High Incidence Scenario.

Luca Elli, Gian Eugenio Tontini, Lucia Scaramella, Paolo Cantù, Matilde Topa, Bernardo Dell'Osso, Antonio Muscatello, Andrea Gori, Helmut Neumann, Maurizio Vecchi, Roberto Penagini,

. ... Read more >>

J Gastrointestin Liver Dis (Journal of gastrointestinal and liver diseases : JGLD)
[2020, 29(3):295-299]

Cited: 1 time

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Covid-19 pandemic impact on colonoscopy service and suggestions for managing recovery.

Sergio Cadoni, Sauid Ishaq, Cesare Hassan, Pradeep Bhandari, Helmut Neumann, Toshio Kuwai, Noriya Uedo, Adolfo Parra-Blanco, Chris J J Mulder, Kenneth F Binmoeller, Felix W Leung,

Background and aim  As the post-peak phase of the epidemic is approaching, there is an urgent need of an action plan to help resume endoscopy activity. To manage the Covid-19 pandemic-imposed backlog of postponed colonoscopy examinations, an efficient approach is needed. The practice of on-demand sedation with benzodiazepines and/or opiates ... Read more >>

Endosc Int Open (Endoscopy international open)
[2020, 8(7):E985-E989]

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Correction: Endoscopic management of gastrointestinal motility disorders - part 2: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Bas L A M Weusten, Maximilien Barret, Albert J Bredenoord, Pietro Familiari, Jean-Michel Gonzalez, Jeanin E van Hooft, Vicente Lorenzo-Zúñiga, Hubert Louis, Jan Martinek, Suzanne van Meer, Helmut Neumann, Daniel Pohl, Frederic Prat, Daniel von Renteln, Edoardo Savarino, Rami Sweis, Jan Tack, Radu Tutuian, Sauid Ishaq,

Endoscopy (Endoscopy)
[2020, 52(7):C7]

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Correction: Endoscopic management of gastrointestinal motility disorders - part 1: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Bas L A M Weusten, Maximilien Barret, Albert J Bredenoord, Pietro Familiari, Jan-Michel Gonzalez, Jeanin E van Hooft, Sauid Ishaq, Vicente Lorenzo-Zúñiga, Hubert Louis, Suzanne van Meer, Helmut Neumann, Daniel Pohl, Frederic Prat, Daniel von Renteln, Edoardo Savarino, Rami Sweis, Jan Tack, Radu Tutuian, Jan Martinek,

Endoscopy (Endoscopy)
[2020, 52(6):C6]

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