Full Text Journal Articles by
Author Helen M Branson


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Association of outcomes in acute flaccid myelitis with identification of enterovirus at presentation: a Canadian, nationwide, longitudinal study.

Carmen Yea, Ari Bitnun, Helen M Branson, Beyza Ciftci-Kavaklioglu, Mubeen F Rafay, Olivier Fortin, Paola Moresoli, Guillaume Sébire, Myriam Srour, Hélène Decaluwe, Louis Marois, Félixe Pelletier, Michelle Barton, Maryam Nabavi Nouri, Jason Brophy, Sunita Venkateswaran, Daniela Pohl, Kathryn Selby, Kevin Jones, Joan Robinson, Aleksandra Mineyko, Christoph Licht, Birgit Ertl-Wagner, E Ann Yeh,

BACKGROUND:Acute flaccid myelitis (AFM) is characterised by rapid onset of limb weakness with spinal cord grey-matter abnormalities on MRI scan. We aimed to assess whether detection of enterovirus in respiratory or other specimens can help predict prognosis in children with AFM. METHODS:In this nationwide, longitudinal study, we evaluated the significance ... Read more >>

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, 4(11):828-836]

Cited: 0 times

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Location and Size of Preterm Cerebellar Hemorrhage and Childhood Development.

Jarred Garfinkle, Ting Guo, Anne Synnes, Vann Chau, Helen M Branson, Steven Ufkes, Emily W Y Tam, Ruth E Grunau, Steven P Miller,

OBJECTIVE:To examine the association between cerebellar hemorrhage (CBH) size and location and preschool-age neurodevelopment in very preterm neonates. METHODS:Preterm magnetic resonance images of 221 very preterm neonates (median gestational age = 27.9 weeks) were manually segmented for CBH quantification and location. Neurodevelopmental assessments at chronological age 4.5 years included motor (Movement Assessment ... Read more >>

Ann Neurol (Annals of neurology)
[2020, 88(6):1095-1108]

Cited: 0 times

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Three-Dimensional Computed Tomography Reconstruction Unmasks Shunt Disconnection in a Child.

Jignesh K Tailor, Ian C Coulter, Michael C Dewan, Helen M Branson, Peter B Dirks, James T Rutka,

Can J Neurol Sci (The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques)
[2020, 47(6):826-827]

Cited: 0 times

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Therapeutic hypothermia for hypoxic-ischemic encephalopathy after perinatal sentinel events: less brain injury on MRI and improved neurodevelopmental outcome at 18-36 months.

Beate Grass, Amr El Shahed, Linh G Ly, Vann Chau, Helen M Branson, Susan Blaser, Kyle Runeckles, Diane Wilson, Hilary Whyte,

OBJECTIVE:To study the association between perinatal sentinel events (PSE) and brain MRI/neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy (HIE) receiving therapeutic hypothermia (TH). DESIGN:This is a retrospective single-center study. Data collection included perinatal history, brain MRI, and neurodevelopmental outcome. RESULTS:Out of the 182 neonates, 53 (29%) neonates had PSE and ... Read more >>

J Perinatol (Journal of perinatology : official journal of the California Perinatal Association)
[2020, 40(4):633-639]

Cited: 0 times

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Associations Between Age at Arterial Switch Operation, Brain Growth, and Development in Infants With Transposition of the Great Arteries.

Jessie Mei Lim, Prashob Porayette, Davide Marini, Vann Chau, Stephanie H Au-Young, Amandeep Saini, Linh G Ly, Susan Blaser, Manohar Shroff, Helen M Branson, Renee Sananes, Edward J Hickey, J William Gaynor, Glen Van Arsdell, Steven P Miller, Mike Seed,

BACKGROUND:Brain injury, impaired brain growth, and long-term neurodevelopmental problems are common in children with transposition of the great arteries. We sought to identify clinical risk factors for brain injury and poor brain growth in infants with transposition of the great arteries undergoing the arterial switch operation, and to examine their ... Read more >>

Circulation (Circulation)
[2019, 139(24):2728-2738]

Cited: 1 time

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White matter injury predicts disrupted functional connectivity and microstructure in very preterm born neonates.

Emma G Duerden, Sheliza Halani, Karin Ng, Ting Guo, Justin Foong, Torin J A Glass, Vann Chau, Helen M Branson, John G Sled, Hilary E Whyte, Edmond N Kelly, Steven P Miller,

OBJECTIVE:To determine whether the spatial extent and location of early-identified punctate white matter injury (WMI) is associated with regionally-specific disruptions in thalamocortical-connectivity in very-preterm born neonates. METHODS:37 very-preterm born neonates (median gestational age: 28.1 weeks; interquartile range [IQR]: 27-30) underwent early MRI (median age 32.9 weeks; IQR: 32-35), and WMI was identified ... Read more >>

Neuroimage Clin (NeuroImage. Clinical)
[2019, 21:101596]

Cited: 6 times

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Physical activity and dentate gyrus volume in pediatric acquired demyelinating syndromes.

Giulia Longoni, Robert A Brown, Berengere Aubert-Broche, Stephanie A Grover, Helen M Branson, Dumitru Fetco, Amit Bar-Or, Ruth Ann Marrie, Robert W Motl, D Louis Collins, Sridar Narayanan, Douglas L Arnold, Brenda Banwell, E Ann Yeh,

To assess the association between daily moderate-to-vigorous physical activity (MVPA) and dentate gyrus volume (DGv) in pediatric patients with acquired demyelinating syndromes (ADSs) of the CNS.Cross-sectional analysis of accelerometry (7 days) and research protocol MRI data from 12 pediatric MS and 18 children with monophasic ADS (monoADS). Total brain and ... Read more >>

Neurol Neuroimmunol Neuroinflamm (Neurology(R) neuroimmunology & neuroinflammation)
[2018, 5(6):e499]

Cited: 1 time

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MRI and laboratory features and the performance of international criteria in the diagnosis of multiple sclerosis in children and adolescents: a prospective cohort study.

Giulia Fadda, Robert A Brown, Giulia Longoni, Denise A Castro, Julia O'Mahony, Leonard H Verhey, Helen M Branson, Patrick Waters, Amit Bar-Or, Ruth Ann Marrie, E Ann Yeh, Sridar Narayanan, Douglas L Arnold, Brenda Banwell, ,

BACKGROUND:MRI and laboratory features have been incorporated into international diagnostic criteria for multiple sclerosis. We assessed the pattern of MRI lesions and contributions of cerebrospinal fluid (CSF) and serum antibody findings that best identifies children with multiple sclerosis, and the applicability of international diagnostic criteria in the paediatric context. METHODS:In ... Read more >>

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2018, 2(3):191-204]

Cited: 7 times

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Quantitative assessment of white matter injury in preterm neonates: Association with outcomes.

Ting Guo, Emma G Duerden, Elysia Adams, Vann Chau, Helen M Branson, M Mallar Chakravarty, Kenneth J Poskitt, Anne Synnes, Ruth E Grunau, Steven P Miller,

To quantitatively assess white matter injury (WMI) volume and location in very preterm neonates, and to examine the association of lesion volume and location with 18-month neurodevelopmental outcomes.Volume and location of WMI was quantified on MRI in 216 neonates (median gestational age 27.9 weeks) who had motor, cognitive, and language ... Read more >>

Neurology (Neurology)
[2017, 88(7):614-622]

Cited: 28 times

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Stochastic process for white matter injury detection in preterm neonates.

Irene Cheng, Steven P Miller, Emma G Duerden, Kaiyu Sun, Vann Chau, Elysia Adams, Kenneth J Poskitt, Helen M Branson, Anup Basu,

Preterm births are rising in Canada and worldwide. As clinicians strive to identify preterm neonates at greatest risk of significant developmental or motor problems, accurate predictive tools are required. Infants at highest risk will be able to receive early developmental interventions, and will also enable clinicians to implement and evaluate ... Read more >>

Neuroimage Clin (NeuroImage. Clinical)
[2015, 7:622-630]

Cited: 3 times

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Multicystic demyelinating myelopathy: widening spectrum of pediatric aquaporin-4 autoimmunity.

Giulia Longoni, Sandra Bigi, Helen M Branson, Cynthia Hawkins, James T Rutka, Massimo Filippi, E Ann Yeh,

Neurology (Neurology)
[2014, 82(10):902-903]

Cited: 0 times

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Normal myelination: a practical pictorial review.

Helen M Branson,

MRI is currently the best imaging modality to assess myelin maturation in the human brain. Myelin is the insulator for nerves and is present in both the peripheral nervous system and the central nervous system (CNS). In the CNS, it is a modified extension of the oligodendrocyte cell and is ... Read more >>

Neuroimaging Clin. N. Am. (Neuroimaging clinics of North America)
[2013, 23(2):183-195]

Cited: 11 times

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Childhood transverse myelitis and its mimics.

Terrence Thomas, Helen M Branson,

Childhood transverse myelitis is an acute inflammatory disorder of the spinal cord with a risk of permanent disability. A timely and accurate diagnosis is imperative, and the radiologist needs to discern between a variety of extra-axial and spinal cord abnormalities that produce similar symptoms but require vastly differing treatments. This ... Read more >>

Neuroimaging Clin. N. Am. (Neuroimaging clinics of North America)
[2013, 23(2):267-278]

Cited: 2 times

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Temporal and occipital lobe features in children with hypochondroplasia/FGFR3 gene mutation.

Cristina M Philpott, Elysa Widjaja, Charles Raybaud, Helen M Branson, Peter Kannu, Susan Blaser,

Thanatophoric dysplasia (TD) and hypochondroplasia are both caused by FGFR3 (fibroblast growth factor receptor 3) gene mutations. Temporal lobe dysplasia has been well described in thanatophoric dysplasia; however, only a couple of anecdotal cases of temporal lobe dysplasia in hypochondroplasia have been described.To define temporal lobe abnormalities in patients with ... Read more >>

Pediatr Radiol (Pediatric radiology)
[2013, 43(9):1190-1195]

Cited: 12 times

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2010 McDonald criteria for diagnosing pediatric multiple sclerosis.

Yair Sadaka, Leonard H Verhey, Manohar M Shroff, Helen M Branson, Douglas L Arnold, Sridar Narayanan, John G Sled, Amit Bar-Or, A Dessa Sadovnick, Melissa McGowan, Ruth Ann Marrie, Brenda Banwell, ,

OBJECTIVE: The diagnosis of multiple sclerosis (MS) rests on confirmation of central nervous system inflammatory disease that is disseminated in space and time, as evidenced clinically or by magnetic resonance imaging (MRI). The 2010 McDonald criteria simplified MRI requirements, and newly proposed that the criteria are also suitable for the ... Read more >>

Ann Neurol (Annals of neurology)
[2012, 72(2):211-223]

Cited: 54 times

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The demographic, clinical, and magnetic resonance imaging (MRI) features of transverse myelitis in children.

Terrence Thomas, Helen M Branson, Leonard H Verhey, Manohar Shroff, Derek Stephens, Sandra Magalhaes, Brenda Banwell,

The authors collected demographic, clinical, and neuroimaging data prospectively on 38 children with transverse myelitis. One child died during the illness. The female:male ratio was 1.2:1 for children under age 10 years and 2.6:1 over age 10 years. Twenty-eight (74%) reported a prodromal event. Twenty-two patients (58%) had longitudinally extensive ... Read more >>

J. Child Neurol. (Journal of child neurology)
[2012, 27(1):11-21]

Cited: 22 times

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Craniosynostosis and 3-dimensional computed tomography.

Helen M Branson, Manohar M Shroff,

Craniosynostosis is when cranial sutures fuse prematurely. It causes cosmetic deformity and may limit brain growth with more serious consequences, such as hydrocephalus. It may involve one or more sutures, may be syndromic, and is thought most likely to result from genetic causes. Specific sutural closures result in reproducible cranial ... Read more >>

Semin. Ultrasound CT MR (Seminars in ultrasound, CT, and MR)
[2011, 32(6):569-577]

Cited: 7 times

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MRI parameters for prediction of multiple sclerosis diagnosis in children with acute CNS demyelination: a prospective national cohort study.

Leonard H Verhey, Helen M Branson, Manohar M Shroff, David Ja Callen, John G Sled, Sridar Narayanan, A Dessa Sadovnick, Amit Bar-Or, Douglas L Arnold, Ruth Ann Marrie, Brenda Banwell, ,

BACKGROUND: Multiple sclerosis (MS) diagnostic criteria incorporate MRI features that can be used to predict later diagnosis of MS in adults with acute CNS demyelination. To identify MRI predictors of a subsequent MS diagnosis in a paediatric population, we created a standardised scoring method and applied it to MRI scans ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2011, 10(12):1065-1073]

Cited: 64 times

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Magnetic resonance imaging features of the spinal cord in pediatric multiple sclerosis: a preliminary study.

Leonard H Verhey, Helen M Branson, Monica Makhija, Manohar Shroff, Brenda Banwell,

Spinal cord lesions in adults with multiple sclerosis (MS) are thought to contribute to disability. The magnetic resonance imaging (MRI) appearance and clinical correlates of spinal cord lesions in children with MS have not been reported.T1-weighted pre- and post-gadolinium and T2-weighted TSE/FSE spine MR images of 36 children (age, 14.3 ... Read more >>

Neuroradiology (Neuroradiology)
[2010, 52(12):1153-1162]

Cited: 24 times

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Best cases from the AFIP: Trilateral retinoblastoma.

Susan H James, William C Halliday, Helen M Branson,

Radiographics (Radiographics : a review publication of the Radiological Society of North America, Inc)
[2010, 30(3):833-837]

Cited: 4 times

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Transient visual loss and isolated disk edema in juvenile nasopharyngeal angiofibroma.

Anamika Tandon, Helen M Branson, J Raymond Buncic,

Juvenile nasopharyngeal angiofibroma is a well-described but rare benign tumor that mainly affects adolescent boys. Although it is capable of extravagant local extension and tissue destruction, the tumor is amenable to effective therapy. Ocular or visual complications have been little noted in the literature. We report a case whose sole ... Read more >>

J AAPOS (Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus)
[2010, 14(1):90-92]

Cited: 1 time

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The brain in children: is contrast enhancement really needed after obtaining normal unenhanced CT results?

Helen M Branson, Andrea S Doria, Rahim Moineddin, Manohar M Shroff,

PURPOSE: To retrospectively determine and compare the sensitivity and specificity of unenhanced and contrast material-enhanced computed tomography (CT) (reference standard) in the diagnosis of brain abnormalities and to evaluate any change in diagnosis that resulted from the contrast-enhanced study. MATERIALS AND METHODS: This study was approved by the local research ... Read more >>

Radiology (Radiology)
[2007, 244(3):838-844]

Cited: 4 times

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