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Author Hao Fan

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A stable organic dye catholyte for long-life aqueous flow batteries.

Hongbin Li, Hao Fan, Mahalingam Ravivarma, Bo Hu, Yangyang Feng, Jiangxuan Song,

An organic dye, Basic blue 3 (BB3), was reported for the first time as a two-electron catholyte for aqueous redox flow batteries. The exceptional stability of BB3 enabled the full battery to achieve a high capacity retention of >99.991% per cycle during 1500 cycles. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(89):13824-13827]

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HERFD-XANES probes of electronic structures of ironII/III carbene complexes.

Meiyuan Guo, Om Prakash, Hao Fan, Lisa H M de Groot, Valtýr Freyr Hlynsson, Simon Kaufhold, Olga Gordivska, Nicolás Velásquez, Pavel Chabera, Pieter Glatzel, Kenneth Wärnmark, Petter Persson, Jens Uhlig,

Iron centered N-heterocyclic carbene (Fe-NHC) complexes have shown long-lived excited states with charge transfer character useful for light harvesting applications. Understanding the nature of the metal-ligand bond is of fundamental importance to rationally tailor the properties of transition metal complexes. The high-energy-resolution fluorescence detected X-ray absorption near edge structure (HERFD-XANES) ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2020, 22(16):9067-9073]

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Mechanism-based Inactivation of Cytochrome P450 3A4 by Benzbromarone.

Lloyd Wei Tat Tang, Ravi Kumar Verma, Hao Fan, Eric Chun Yong Chan,

Benzbromarone (BBR), a potent uricosuric agent for the management of gout, is known to cause fatal fulminant hepatitis. While the mechanism of BBR-induced idiosyncratic hepatotoxicity remains unelucidated, cytochrome P450 enzyme (CYP450)-mediated bioactivation of BBR to electrophilic reactive metabolites is commonly regarded as a key molecular-initiating event. However, apart from causing ... Read more >>

Mol Pharmacol (Molecular pharmacology)
[2021, :]

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Analysis of the external acoustic meatus for ergonomic design: part II - anthropometric variations of the external acoustic meatus by sex, age and side in Chinese population.

Hao Fan, Suihuai Yu, Mengcheng Wang, Mei Li, Xiao Zhao, Yihui Ren, Shuai Zhang, Dengkai Chen, Carisa Harris Adamson,

For devices worn inside the ear, detailed anthropometric data of the external acoustic meatus (EAM) is needed, yet lacking due to the complex and costly methodology associated with attaining such measurements. The purpose of this study was to provide the anthropometric characteristics of the EAM including variations by age group, ... Read more >>

Ergonomics (Ergonomics)
[2021, :1-12]

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Analysis of the external acoustic meatus for ergonomic design: part I - measurement of the external acoustic meatus using casting, scanning and rapid estimation approaches.

Hao Fan, Suihuai Yu, Mengcheng Wang, Mei Li, Jianjie Chu, Yishu Yan, Shuai Zhang, Dengkai Chen, Carisa Harris-Adamson,

Numerous ear-related wearables require precise measurements of the external acoustic meatus (EAM) to optimise function and comfort. The purpose of this study is to describe a novel methodology for measuring the EAM. A total of 23 measurement variables (18 novel) of the EAM from the entrance to the second bend ... Read more >>

Ergonomics (Ergonomics)
[2021, :1-18]

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From a layered iridium(iii)-cobalt(ii) organophosphonate to an efficient oxygen-evolution-reaction electrocatalyst.

Chwen-Haw Liao, Kun Fan, Song-Song Bao, Hao Fan, Xi-Zhang Wang, Zheng Hu, Mohamedally Kurmoo, Li-Min Zheng,

Bimetallic MOF precursors can produce a homogeneous distribution of mixed-metal oxides after calcination, and thus may provide high efficiency as electrocatalysts in the water splitting process. We designed a layered bimetallic-organophosphonate containing Ir, Co and P because the metal-oxides are well-known for their efficiency in the oxygen-evolution reaction (OER), especially ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2019, 55(92):13920-13923]

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Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism.

Andra C Dumitru, R N V Krishna Deepak, Heng Liu, Melanie Koehler, Cheng Zhang, Hao Fan, David Alsteens,

A current challenge to produce effective therapeutics is to accurately determine the location of the ligand-biding site and to characterize its properties. So far, the mechanisms underlying the functional activation of cell surface receptors by ligands with a complex binding mechanism remain poorly understood due to a lack of suitable ... Read more >>

Commun Biol (Communications biology)
[2020, 3(1):786]

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Meta-Analysis of Randomized Controlled Trials of Xueshuantong Injection in Prevention of Deep Venous Thrombosis of Lower Extremity after Orthopedic Surgery.

Shu-Ting Yan, Feng Gao, Tai-Wei Dong, Hao Fan, Miao-Miao Xi, Feng Miao, Pei-Feng Wei,

<h4>Objective</h4>To systematically evaluate the clinical efficacy of Xueshuantong injection (<i>Panax notoginseng</i> saponins) in preventing deep venous thrombosis (DVT) of lower extremity after orthopedic surgery.<h4>Methods</h4>The randomized controlled trials (RCTs) of Xueshuantong injection in prevention of lower extremity DVT after orthopedic surgery were retrieved from CNKI, Wanfang database, VIP, PubMed, and Cochrane ... Read more >>

Evid Based Complement Alternat Med (Evidence-based complementary and alternative medicine : eCAM)
[2020, 2020:8877791]

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Disparities of perceived wellness by smoking and professional status among young individuals in Brasov, Brasov County, Romania.

Hao Fan, Xiang Gao, Haiping Wang, Mihaela Idomir, Liliana Rogozea, Ana-Maria Cazan, Aurelian Bidulescu, Mihaela Badea,

<h4>Objective</h4>We aimed to evaluate the association of risk factors such as smoking and professional status (students vs employed) as determinants of disparities in perceived wellness among Romanian individuals.<h4>Methods</h4>We conducted a cross-sectional study in which 145 participants were enrolled from December 2017 to February 2018, in Brasov, Brasov County, Transylvania, Romania. ... Read more >>

SAGE Open Med (SAGE open medicine)
[2020, 8:2050312120973483]

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In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation.

Kishore Reddy Venkata Thappeta, Li Na Zhao, Choy Eng Nge, Sharon Crasta, Chung Yan Leong, Veronica Ng, Yoganathan Kanagasundaram, Hao Fan, Siew Bee Ng,

Sortase A (SrtA) is a membrane-associated enzyme that anchors surface-exposed proteins to the cell wall envelope of Gram-positive bacteria such as <i>Staphylococcus aureus</i>. As SrtA is essential for Gram-positive bacterial pathogenesis but dispensable for microbial growth or viability, SrtA is considered a favorable target for the enhancement of novel anti-infective ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(22):]

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Acupuncture attenuates cognitive deficits through α7nAChR mediated anti-inflammatory pathway in chronic cerebral hypoperfusion rats.

Yan Cao, Lu Wang, Li-Ting Lin, Xue-Rui Wang, Si-Ming Ma, Na-Na Yang, Hao Fan, Marc Fisher, Jing-Wen Yang,

<h4>Aims</h4>Chronic cerebral hypoperfusion (CCH) elicits inflammatory response, which contributes to the pathology of cognitive impairment. Several studies demonstrate that the alpha-7 nicotinic acetylcholine receptor (α7nAChR) can be a key component to modulate the inflammatory responses. We have reported previously that acupuncture attenuated cognitive deficits induced by CCH. In present study, ... Read more >>

Life Sci (Life sciences)
[2020, 266:118732]

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The Comparison of STA-MCA Bypass and BMT for Symptomatic Internal Carotid Artery Occlusion Disease A Systematic Review and Meta-analysis of Long-term Outcome

Xinyu Yang, Shifei Cai, Hao Fan, Chao Peng, Yuzhang Wu,

<h4>Background: </h4> Superficial temporal artery (STA) - middle cerebral artery (MCA) bypass surgery now being widely used in moyamoya disease, and its therapeutic value in SICAO remains divergent. <h4>Methods: </h4> A systematic search was performed in PUBMED, EMBASE and Cochrane Databases in Feb.2020, and updated in Jun.2019. We have strict ... Read more >>

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Structure-Activity Relationships of Noncovalent Immunoproteasome β5i-Selective Dipeptides.

Wenhu Zhan, Pradeep K Singh, Yi Ban, Xiaoping Qing, Marie Dominique Ah Kioon, Hao Fan, Quanju Zhao, Rong Wang, George Sukenick, Jane Salmon, J David Warren, Xiaojing Ma, Franck J Barrat, Carl F Nathan, Gang Lin,

The immunoproteasome (i-20S) has emerged as a therapeutic target for autoimmune and inflammatory disorders and hematological malignancies. Inhibition of the chymotryptic β5i subunit of i-20S inhibits T cell activation, B cell proliferation, and dendritic cell differentiation in vitro and suppresses immune responses in animal models of autoimmune disorders and allograft ... Read more >>

J Med Chem (Journal of medicinal chemistry)
[2020, 63(21):13103-13123]

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The effectiveness of moxibustion for treating of low back pain: A protocol for systematic review and meta-analysis.

Siyuan Zhu, Jun Xiong, Jun Chen, Genhua Tang, Zhiying Zhong, LunBin Lu, Xingchen Zhou, Han Guo, Hao Fan,

<h4>Background</h4>Low back pain is a common clinical chronic disease with symptoms of back soreness, numbness, and pain. The incidence of low back pain is high, and gradually increases with age. It is mainly middle-aged and has a high recurrence rate. It is considered to be one of the common diseases ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(43):e22522]

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An electrochemical Hg2+ sensor based on signal amplification strategy of target recycling.

You Quan Zhong, Tian Jiao Ning, Lin Cheng, Wei Xiong, Guo Bing Wei, Fu Sheng Liao, Guang Qiang Ma, Nian Hong, Han Feng Cui, Hao Fan,

In this work, an unmodified homogeneous electrochemical sensor based on electrochemical bonding and catalytic hairpin assembly (CHA) was first constructed for the high sensitivity detection of Hg<sup>2+</sup>. Herein, tetraferrocene, a synthesized compound, was used as a signal marker that modified both ends of the hairpin probe to amplify the electrochemical ... Read more >>

Talanta (Talanta)
[2021, 223(Pt 1):121709]

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Radical Charge Population and Energy: Critical Role in Redox Potential and Cycling Life of Piperidine Nitroxyl Radical Cathodes in Aqueous Zinc Hybrid Flow Batteries.

Hao Fan, Jiahui Zhang, Mahalingam Ravivarma, Hongbin Li, Bo Hu, Jiafeng Lei, Yangyang Feng, Shizhao Xiong, Cheng He, Jianying Gong, Tieyu Gao, Jiangxuan Song,

Redox-active 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) derivatives have recently been investigated to expand the choice of catholyte for aqueous flow batteries (AFBs). However, the effects of substituent R in 4-position on redox potential and corresponding capacity fading mechanism are still unclear. Here, we conduct comparative studies of four R-TEMPO with R = -OH, ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(39):43568-43575]

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Effectiveness and Safety of Plum - Blossom Needle in the Treatment of Myopia:A Protocol for Systematic Review and Meta-analysis

Siyuan Zhu, Jun Xiong, Jun Chen, Genhua Tang, Lunbin Lu, Zhiying Zhong, Xingchen Zhou, Han Guo, Hao Fan,

<h4>Background: </h4> In recent years, the prevalence of myopia has increased significantly, and it has become one of the major eye diseases that cause visual impairment in the world,which is particularly prominent among young people. And uncorrected myopia is the leading cause of blindness.The purpose of this study is to ... Read more >>

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Modification and utility of a rat burn wound model.

Xiaoyan Hu, Xingxia Wang, Xudong Hong, Hao Fan, Xudong Zhang, Aifen Chen, Guangyi Wang, Jian Jin, Zhaofan Xia,

This study aimed to improve the conventional rat burn wound model and to validate its utility. In total, 60 Sprague-Dawley rats were divided equally into the control and experimental groups. Altogether, 60 burn wound models with zones of stasis were created in each group. Gross visual assessments of the burn ... Read more >>

Wound Repair Regen (Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society)
[2020, 28(6):797-811]

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Atmospheric inverse estimates of CO emissions from Zhengzhou, China.

Hao Fan, Chuanfeng Zhao, Zhanshan Ma, Yikun Yang,

Carbon monoxide (CO) is an important gas that affects human health and causes air pollution. However, the estimates of CO emissions in China are still subject to large uncertainties. Based on the CO mass concentration and the coupled Weather Research and Forecast (WRF) and Stochastic Time-Inverted Lagrangian Transport (STILT) model ... Read more >>

Environ Pollut (Environmental pollution (Barking, Essex : 1987))
[2020, 267:115164]

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Virtual screening of potentially endocrine-disrupting chemicals against nuclear receptors and its application to identify PPARγ-bound fatty acids.

Chaitanya K Jaladanki, Yang He, Li Na Zhao, Sebastian Maurer-Stroh, Lit-Hsin Loo, Haiwei Song, Hao Fan,

Nuclear receptors (NRs) are key regulators of energy homeostasis, body development, and sexual reproduction. Xenobiotics binding to NRs may disrupt natural hormonal systems and induce undesired adverse effects in the body. However, many chemicals of concerns have limited or no experimental data on their potential or lack-of-potential endocrine-disrupting effects. Here, ... Read more >>

Arch Toxicol (Archives of toxicology)
[2021, 95(1):355-374]

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The Effectiveness of Acupuncture and Moxibustion for Rheumatoid Arthritis: A Protocol of an Overview of Systematic Reviews and Meta-analysis

Genhua Tang, Jun Xiong, Siyuan Zhu, Zhiying Zhong, Jun Chen, Lunbin Lu, Han Guo, Xingchen Zhou, Hao Fan,

<h4>Background: </h4> Rheumatoid Arthritis(RA) is a common chronic disease with an annual incidence of 25 per 10000 of the population, which will result in severe joint damage,disability and death. It is strongly supported by systematic reviews (SRs) as part of the treatment of these patients. However, the evidence has not ... Read more >>

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Peroxisome proliferator-activated receptor-γ mediates the antihypertensive effects of acupuncture in spontaneously hypertensive rats.

Hao Fan, Jing-Wen Yang, Jin Huang, Lu Wang, Na-Na Yang, Jian-Feng Tu, Cun-Zhi Liu,

We investigated a central antihypertensive effect of acupuncture in rostral ventrolateral medulla (RVLM) in spontaneously hypertensive rats (SHRs). In total, 56 rats were randomly divided into seven groups as follows: the SHR group, SHR+acupuncture (SHR+Acu) group, SHR+nonacupuncture (SHR+Non-acu) group, GW9662+acupuncture (GW9662+Acu) group, GW9662+GW1929 group, GW9662 group, and 2% DMSO group ... Read more >>

Neuroreport (Neuroreport)
[2020, 31(13):952-958]

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A Protocol to Develop Practical Guidelines for Management of Primary Dysmenorrhea with Moxibustion

Shouqiang Huang, Jun Xiong, Yong Fu, Fanghui Hua, Jie Xiang, Hao Fan, Yunfeng Jiang, Xiaohong Zhou, Kai Liao, Lingling Xu, Haifeng Zhang,

<h4>Background: </h4> Primary dysmenorrhea (PD) is a common gynecological disease characterized by lower abdominal pain. Moxibustion as a traditional Chinese treatment, can effectively treat PD with few adverse reactions. Nowadays, there is still no standard guideline for moxibustion treatment of PD, so related clinical practice guidelines (CPG) need to be ... Read more >>

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Associations of dietary habits and sleep in older adults: a 9-year follow-up cohort study.

Hao Fan, Yen-Han Lee, Yen-Chang Chang, Mack Shelley,

<h4>Purpose</h4>China has faced rapid growth of its older adult population, shifting dietary landscape, and sleep-related problems. However, knowledge regarding the associations of dietary behavior on sleep-related outcomes with longitudinal data remains limited. This study investigates the relationships of dietary habits with sleep quality and duration.<h4>Methods</h4>Using data from the Chinese Longitudinal ... Read more >>

Eur Geriatr Med (European geriatric medicine)
[2020, :]

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Enhanced thermal stability of lactic acid bacteria during spray drying by intracellular accumulation of calcium

Yan Wang, Fan Hao, Wenjie Lu, Xiangshu Suo, Elise Bellenger, Nan Fu, Romain Jeantet, Xiao Dong Chen,

Lactococcus lactis ssp. cremoris and Lactobacillus acidophilus NCFM were cultured in growth media supplemented with CaCl2 to induce intracellular accumulation of Ca2+. Both strains grown with 10 mM Ca2+ demonstrated enhanced thermal stability, with increased survival after spray drying from 49.9% to 64.9% for the coccus and from 35.5% to ... Read more >>

(Journal of food engineering.)
[2020, 279:Not Available]

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