Tomer Fekete, Hermann Hinrichs, Jacobo Diego Sitt, Hans-Jochen Heinze, Oren Shriki,
The brain is universally regarded as a system for processing information. If so, any behavioral or cognitive dysfunction should lend itself to depiction in terms of information processing deficiencies. Information is characterized by recursive, hierarchical complexity. The brain accommodates this complexity by a hierarchy of large/slow and small/fast spatiotemporal loops ... Read more >>
Sci Rep (Scientific reports)
[2021, 11(1):14441]
Cited: 0 times
Catherine M Sweeney-Reed, Lars Buentjen, Jürgen Voges, Friedhelm C Schmitt, Tino Zaehle, Julia W Y Kam, Jörn Kaufmann, Hans-Jochen Heinze, Hermann Hinrichs, Robert T Knight, Michael D Rugg,
Extensive neuroanatomical connectivity between the anterior thalamic nuclei (ATN) and hippocampus and neocortex renders them well-placed for a role in memory processing, and animal, lesion, and neuroimaging studies support such a notion. The deep location and small size of the ATN have precluded their real-time electrophysiological investigation during human memory ... Read more >>
Neurosci Biobehav Rev (Neuroscience and biobehavioral reviews)
[2021, 126:146-158]
Cited: 0 times
Dominik Thuberg, Lars Buentjen, Martin Holtkamp, Jürgen Voges, Hans-Jochen Heinze, Harim Lee, Ann-Yasmin Kitay, Friedhelm C Schmitt,
<h4>Introduction</h4>Following electrode implantation, a subgroup of patients treated with deep brain stimulation (DBS) for focal epilepsy exhibits a reduction of seizure frequency before stimulation is initiated. Microlesioning of the target structure has been postulated to be the cause of this "insertional" effect (IE). We examined the occurrence and duration of ... Read more >>
Neuromodulation (Neuromodulation : journal of the International Neuromodulation Society)
[2021, 24(2):373-379]
Cited: 0 times
Johanna Rotta, Valentina Perosa, Renat Yakupov, Hugo J Kuijf, Frank Schreiber, Laura Dobisch, Jan Oltmer, Anne Assmann, Oliver Speck, Hans-Jochen Heinze, Julio Acosta-Cabronero, Emrah Duzel, Stefanie Schreiber,
<h4>Objective</h4>Cerebral microbleeds (MBs) are a common finding in patients with cerebral small vessel disease (CSVD) and Alzheimer disease as well as in healthy elderly people, but their pathophysiology remains unclear. To investigate a possible role of veins in the development of MBs, we performed an exploratory study, assessing in vivo ... Read more >>
Neurology (Neurology)
[2021, 96(16):e2048-e2057]
Cited: 1 time
Christian Wienke, Mandy V Bartsch, Lena Vogelgesang, Christoph Reichert, Hermann Hinrichs, Hans-Jochen Heinze, Stefan Dürschmid,
Mind-wandering (MW) is a subjective, cognitive phenomenon, in which thoughts move away from the task toward an internal train of thoughts, possibly during phases of neuronal sleep-like activity (local sleep, LS). MW decreases cortical processing of external stimuli and is assumed to decouple attention from the external world. Here, we ... Read more >>
Cereb Cortex Commun (Cerebral cortex communications)
[2021, 2(1):tgab001]
Cited: 0 times
Stefan Dürschmid, Andre Maric, Marcel S Kehl, Robert T Knight, Hermann Hinrichs, Hans-Jochen Heinze,
Impulsive decisions arise from preferring smaller but sooner rewards compared with larger but later rewards. How neural activity and attention to choice alternatives contribute to reward decisions during temporal discounting is not clear. Here we probed (1) attention to and (2) neural representation of delay and reward information in humans ... Read more >>
J Neurosci (The Journal of neuroscience : the official journal of the Society for Neuroscience)
[2021, 41(8):1727-1737]
Cited: 0 times
Nico Lehmann, Norman Aye, Jörn Kaufmann, Hans-Jochen Heinze, Emrah Düzel, Gabriel Ziegler, Marco Taubert,
Diffusion-weighted magnetic resonance imaging (DWI) is undergoing constant evolution with the ambitious goal of developing in-vivo histology of the brain. A recent methodological advancement is Neurite Orientation Dispersion and Density Imaging (NODDI), a histologically validated multi-compartment model to yield microstructural features of brain tissue such as geometric complexity and neurite ... Read more >>
Neuroscience (Neuroscience)
[2021, 457:165-185]
Cited: 1 time
Christoph Reichert, Igor Fabian Tellez Ceja, Catherine M Sweeney-Reed, Hans-Jochen Heinze, Hermann Hinrichs, Stefan Dürschmid,
Regaining communication abilities in patients who are unable to speak or move is one of the main goals in decoding brain waves for brain-computer interface (BCI) control. Many BCI approaches designed for communication rely on attention to visual stimuli, commonly applying an oddball paradigm, and require both eye movements and ... Read more >>
Front Neurosci (Frontiers in neuroscience)
[2020, 14:591777]
Cited: 0 times
Vincent Scheumann, Frank Schreiber, Valentina Perosa, Anne Assmann, Christian Mawrin, Cornelia Garz, Hans-Jochen Heinze, Michael Görtler, Emrah Düzel, Stefan Vielhaber, Andreas Charidimou, Stefanie Schreiber,
<h4>Objective</h4>To investigate underlying cerebral small vessel disease (CSVD) in patients with mixed cerebral hemorrhages patterns and phenotype them according to the contribution of the two most common sporadic CSVD subtypes: cerebral amyloid angiopathy (CAA) vs. hypertensive arteriopathy (HA).<h4>Methods</h4>Brain MRIs of patients with intracerebral hemorrhages (ICHs) and/or cerebral microbleeds (CMBs) were ... Read more >>
J Neurol Sci (Journal of the neurological sciences)
[2020, 419:117173]
Cited: 0 times
Christoph Reichert, Stefan Dürschmid, Mandy V Bartsch, Jens-Max Hopf, Hans-Jochen Heinze, Hermann Hinrichs,
<h4>Objective</h4>One of the main goals of brain-computer interfaces (BCI) is to restore communication abilities in patients. BCIs often use event-related potentials (ERPs) like the P300 which signals the presence of a target in a stream of stimuli. The P300 and related approaches, however, are inherently limited, as they require many ... Read more >>
J Neural Eng (Journal of neural engineering)
[2020, 17(5):056012]
Cited: 0 times
Jana Klimpke, Dorothea Henkel, Hans-Jochen Heinze, Max-Philipp Stenner,
Cerebellar ataxia is associated with an implicit motor learning dysfunction, specifically, a miscalibration of internal models relating motor commands to state changes of the body. Explicit cognitive strategies could compensate for deficits in implicit calibration. Surprisingly, however, patients with cerebellar ataxia use insufficient strategies compared to healthy controls. We report ... Read more >>
Cited: 0 times
Florin Gandor, Manfred Tesch, Hannelore Neuhauser, Doreen Gruber, Hans-Jochen Heinze, Georg Ebersbach, Thomas Lempert,
The article Diagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo‑ocular reflex: when nothing else matters, written by Florin Gandor, Manfred Tesch, Hannelore Neuhauser, Doreen Gruber, Hans‑Jochen Heinze, Georg Ebersbach and Thomas Lempert, was originally published electronically on the publisher's internet portal on 01 ... Read more >>
J Neurol (Journal of neurology)
[2020, 267(10):3118]
Cited: 0 times
Lena Vogelgesang, Christoph Reichert, Hermann Hinrichs, Hans-Jochen Heinze, Stefan Dürschmid,
Unique to humans is the ability to report subjective awareness of a broad repertoire of external and internal events. Even when asked to focus on external information, the human's mind repeatedly wanders to task-unrelated thoughts, which limits reading comprehension or the ability to withhold automated manual responses. This led to ... Read more >>
Front Neurosci (Frontiers in neuroscience)
[2020, 14:552637]
Cited: 0 times
Frank Schreiber, Cornelia Garz, Hans-Jochen Heinze, Susanne Petri, Stefan Vielhaber, Stefanie Schreiber,
Ultrasound has revealed cross-sectional nerve area (CSA) reduction in amyotrophic lateral sclerosis (ALS), but little is known about the sonographic nerve texture beyond CSA alterations. In a large cohort of 177 ALS patients and 57 control subjects, we investigated the covariance and disease-specific signature of several sonographic texture features of ... Read more >>
Muscle Nerve (Muscle & nerve)
[2020, 62(5):601-610]
Cited: 0 times
Florin Gandor, Annemarie Vogel, Inga Claus, Sigrid Ahring, Doreen Gruber, Hans-Jochen Heinze, Rainer Dziewas, Georg Ebersbach, Tobias Warnecke,
<h4>Background</h4>Multiple system atrophy (MSA) is a rare neurodegenerative disorder, and its parkinsonian variant can be difficult to delineate from Parkinson's disease (PD). Despite laryngeal dysfunction being associated with decreased life expectancy and quality of life, systematic assessments of laryngeal dysfunction in large cohorts are missing.<h4>Objectives</h4>The objective of this study was ... Read more >>
Mov Disord (Movement disorders : official journal of the Movement Disorder Society)
[2020, 35(12):2174-2183]
Cited: 2 times
Marc Dörner, Frank Schreiber, Heike Stephanik, Claus Tempelmann, Natalie Winter, Jan-Hendrik Stahl, Julia Wittlinger, Sophia Willikens, Magdalena Kramer, Hans-Jochen Heinze, Stefan Vielhaber, Thomas Schelle, Alexander Grimm, Stefanie Schreiber,
<h4>Background</h4>Diagnosis of immune-mediated neuropathies and their differentiation from amyotrophic lateral sclerosis (ALS) can be challenging, especially at early disease stages. Accurate diagnosis is, however, important due to the different prognosis and available treatment options. We present one patient with a left-sided dorsal flexor paresis and initial suspicion of ALS and ... Read more >>
Diagnostics (Basel) (Diagnostics (Basel, Switzerland))
[2020, 10(8):]
Cited: 1 time
Christian Gronemann, Stephan Hause, Anne Assmann, Jens Neumann, Stefanie Schreiber, Hans-Jochen Heinze, Michael Goertler,
<h4>Introduction</h4>Approximately 1 out of 4 stroke patients suffers ischemic stroke secondary to atrial fibrillation (AF). Although indicated, withholding of anticoagulants for secondary prevention is a widespread phenomenon.<h4>Objective</h4>We examined the longitudinal change of recommendation and prescription of secondary preventive anticoagulation in AF patients in an acute stroke center setting focusing on ... Read more >>
Cerebrovasc Dis (Cerebrovascular diseases (Basel, Switzerland))
[2020, 49(4):412-418]
Cited: 0 times
Christoph Reichert, Stefan Dürschmid, Mandy Bartsch, Jens-Max Hopf, Hans-Jochen Heinze, Hermann Hinrichs,
<h4>Objective</h4> One of the main goals of brain-computer interfaces (BCI) is to restore communication abilities in patients. BCIs often use event-related potentials (ERPs) like the P300 which signals the presence of a target in a stream of stimuli. The P300 and related approaches, however, are inherently limited, as they require ... Read more >>
Cited: 0 times
Philipp Ruhnau, Katharina S Rufener, Hans-Jochen Heinze, Tino Zaehle,
<h4>Background</h4>One key mechanism thought to underlie speech processing is the alignment of cortical brain rhythms to the acoustic input, a mechanism termed entrainment. Recent work showed that transcranial electrical stimulation (tES) in speech relevant frequencies or adapted to the speech envelope can in fact enhance speech processing. However, it is ... Read more >>
Brain Stimul (Brain stimulation)
[2020, 13(5):1402-1411]
Cited: 1 time
Stefan Dürschmid, Christoph Reichert, Nike Walter, Hermann Hinrichs, Hans-Jochen Heinze, Frank W Ohl, Giulio Tononi, Matthias Deliano,
Brain function requires the flexible coordination of billions of neurons across multiple scales. This could be achieved by scale-free, critical dynamics balanced at the edge of order and disorder. Criticality has been demonstrated in several, often reduced neurophysiological model systems. In the intact human brain criticality has yet been only ... Read more >>
PLoS One (PloS one)
[2020, 15(6):e0233589]
Cited: 0 times
Heinrich Maximilian Scheifele, Philipp Ulbrich, Cornelia Garz, Roxana Octavia Carare, Hans-Jochen Heinze, Stefanie Schreiber, Solveig Jandke,
<b>Introduction:</b> The initial disease stages of hypertensive arteriopathy (HA) and cerebral amyloid angiopathy (CAA), the two main forms of sporadic human cerebral small vessel diseases (CSVD), are too subtle to be detectable on clinical routine imaging. Small vessel disease (SVD) is a systemic condition, affecting not only the brain, but ... Read more >>
Front Neurol (Frontiers in neurology)
[2020, 11:533]
Cited: 0 times
Christian Wienke, Mandy Bartsch, Lena Vogelgesang, Christoph Reichert, Hermann Hinrichs, Hans-Jochen Heinze, Stefan Dürschmid,
Mind wandering (MW) is a subjective, cognitive phenomenon, in which thoughts move away from the task towards an internal train of thoughts, possibly during phases of neuronal sleep-like activity (local sleep, LS). MW decreases cortical processing of external stimuli and is assumed to decouple attention from the external world. Here, ... Read more >>
Cited: 0 times
Florin Gandor, Manfred Tesch, Hannelore Neuhauser, Doreen Gruber, Hans-Jochen Heinze, Georg Ebersbach, Thomas Lempert,
<h4>Objective</h4>Validation of a bedside test to objectify the fixation suppression of the vestibulo-ocular reflex (FS-VOR) in patients with a cerebellar syndrome and healthy controls.<h4>Methods</h4>The vestibulo-ocular reflex and its fixation suppression were assessed by video-nystagmography (VNG) in 20 healthy subjects (mean age 56 ± 15) and 19 patients with a cerebellar syndrome (mean ... Read more >>
J Neurol (Journal of neurology)
[2020, 267(7):2159-2163]
Cited: 1 time
Susanne Vogt, Stefanie Schreiber, Giselher Pfau, Katja Kollewe, Hans-Jochen Heinze, Reinhard Dengler, Susanne Petri, Stefan Vielhaber, Michael Brinkers,
<h4>Context</h4>There is no evidence-based treatment for fatigue in amyotrophic lateral sclerosis (ALS), and identification of treatable causes determines management strategies. Although dyspnea is a key symptom of ALS and effectively treatable, it has not been sufficiently investigated whether dyspnea may be a fatigue-promoting factor.<h4>Objectives</h4>To determine the level of fatigue in ... Read more >>
J Pain Symptom Manage (Journal of pain and symptom management)
[2020, 60(2):430-438.e1]
Cited: 0 times
Hermann Hinrichs, Michael Scholz, Anne Katrin Baum, Julia W Y Kam, Robert T Knight, Hans-Jochen Heinze,
Dry electrode electroencephalogram (EEG) recording combined with wireless data transmission offers an alternative tool to conventional wet electrode EEG systems. However, the question remains whether the signal quality of dry electrode recordings is comparable to wet electrode recordings in the clinical context. We recorded the resting state EEG (rsEEG), the ... Read more >>
Sci Rep (Scientific reports)
[2020, 10(1):5218]
Cited: 8 times