Full Text Journal Articles by
Author Hanna Leicht

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Time to Surgery and Outcome in the Treatment of Proximal Femoral Fractures.

Hanna Leicht, Thomas Gaertner, Christian Günster, Andreas M Halder, Reinhard Hoffmann, Elke Jeschke, Jürgen Malzahn, Almut Tempka, Josef Zacher,

<h4>Background</h4>It has not been conclusively established whether, or to what extent, the time to surgery affects mortality and the risk of complications after the surgical treatment of proximal femoral fractures.<h4>Methods</h4>Data on 106 187 hospitalizations over the period 2015-2017 involving insurees of the German AOK health insurance company aged 20 and ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

Cited: 0 times

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Surgical Reintervention Rates after Invasive Treatment for Lower Urinary Tract Symptoms due to Benign Prostatic Syndrome: A Comparative Study of More than 43,000 Patients with Long-Term Followup.

Christian Gilfrich, Matthias May, Claus Fahlenbrach, Christian Günster, Elke Jeschke, Gralf Popken, Jens-Uwe Stolzenburg, Lothar Weissbach, Christoph von Zastrow, Hanna Leicht,

<h4>Purpose</h4>No large-scale comparison of the 4 most established surgical approaches for lower urinary tract symptoms due to benign prostate obstruction in terms of long-term efficacy is available. We compared photoselective vaporization, laser enucleation and open simple prostatectomy to transurethral resection with regard to 5-year surgical reintervention rates.<h4>Materials and methods</h4>A total ... Read more >>

J Urol (The Journal of urology)
[2021, 205(3):855-863]

Cited: 1 time

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Low Hospital Volume Increases Re-Revision Rate Following Aseptic Revision Total Knee Arthroplasty: An Analysis of 23,644 Cases.

Andreas M Halder, Thorsten Gehrke, Christian Günster, Karl-Dieter Heller, Hanna Leicht, Jürgen Malzahn, Fritz U Niethard, Peter Schräder, Josef Zacher, Elke Jeschke,

<h4>Background</h4>Along with rising numbers of primary total knee arthroplasty (TKA), the number of revision total knee arthroplasties (R-TKAs) has been increasing. R-TKA is a complex procedure requiring special instruments, implants, and surgical skills. Therefore it is likely that hospitals with more R-TKAs have more experience with this type of surgery ... Read more >>

J Arthroplasty (The Journal of arthroplasty)
[2020, 35(4):1054-1059]

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Low Hospital Volume Increases Revision Rate and Mortality Following Revision Total Hip Arthroplasty: An Analysis of 17,773 Cases.

Elke Jeschke, Thorsten Gehrke, Christian Günster, Karl-Dieter Heller, Hanna Leicht, Jürgen Malzahn, Fritz Uwe Niethard, Peter Schräder, Josef Zacher, Andreas M Halder,

<h4>Background</h4>With the number of primary total hip arthroplasty (THA), the amount of revision THA (R-THA) increases. R-THA is a complex procedure requiring special instruments, implants, and surgical skills. Therefore it is likely that hospitals performing a higher number of R-THAs have more experience with this type of surgery and therefore ... Read more >>

J Arthroplasty (The Journal of arthroplasty)
[2019, 34(9):2045-2050]

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The impact of social engagement on health-related quality of life and depressive symptoms in old age - evidence from a multicenter prospective cohort study in Germany.

André Hajek, Christian Brettschneider, Tina Mallon, Annette Ernst, Silke Mamone, Birgitt Wiese, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Janine Stein, Tobias Luck, Horst Bickel, Dagmar Weeg, Michael Wagner, Kathrin Heser, Wolfgang Maier, Martin Scherer, Steffi G Riedel-Heller, Hans-Helmut König, ,

<h4>Background</h4>Thus far, only a few longitudinal studies investigated the impact of social engagement on health-related quality of life (HRQoL) and depressive symptoms in old age. Therefore, we aimed to examine the impact of social engagement on HRQoL and depressive symptoms in late life.<h4>Methods</h4>Individuals aged 75 years and over at baseline were ... Read more >>

Health Qual Life Outcomes (Health and quality of life outcomes)
[2017, 15(1):140]

Cited: 11 times

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Longitudinal Predictors of Institutionalization in Old Age.

André Hajek, Christian Brettschneider, Carolin Lange, Tina Posselt, Birgitt Wiese, Susanne Steinmann, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Janine Stein, Tobias Luck, Horst Bickel, Edelgard Mösch, Michael Wagner, Frank Jessen, Wolfgang Maier, Martin Scherer, Steffi G Riedel-Heller, Hans-Helmut König, ,

<h4>Objective</h4>To investigate time-dependent predictors of institutionalization in old age using a longitudinal approach.<h4>Methods</h4>In a representative survey of the German general population aged 75 years and older predictors of institutionalization were observed every 1.5 years over six waves. Conditional fixed-effects logistic regressions (with 201 individuals and 960 observations) were performed to ... Read more >>

PLoS One (PloS one)
[2015, 10(12):e0144203]

Cited: 48 times

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National trends and differences in morbidity among surgical approaches for radical prostatectomy in Germany.

Jens Uwe Stolzenburg, Iason Kyriazis, Claus Fahlenbrach, Christian Gilfrich, Christian Günster, Elke Jeschke, Gralf Popken, Lothar Weißbach, Christoph von Zastrow, Hanna Leicht,

<h4>Objective</h4>In this study, we document trends in radical prostatectomy (RP) employment in Germany during the period 2005-2012 and compare the morbidity of open (ORP), laparoscopic and robotic-assisted RP based on nationwide administrative data of Allgemeine Ortskrankenkassen (AOK) German local healthcare funds.<h4>Materials and methods</h4>Administrative claims data of all AOK patients subjected ... Read more >>

World J Urol (World journal of urology)
[2016, 34(11):1515-1520]

Cited: 8 times

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Prevalence and determinants of overweight and obesity in old age in Germany.

André Hajek, Thomas Lehnert, Annette Ernst, Carolin Lange, Birgitt Wiese, Jana Prokein, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Tobias Luck, Horst Bickel, Edelgard Mösch, Kathrin Heser, Michael Wagner, Wolfgang Maier, Martin Scherer, Steffi G Riedel-Heller, Hans-Helmut König, ,

<h4>Background</h4>Mean body weight gradually increases with age. Yet, little data exists on the prevalence of excess weight in populations aged 80 years or older. Moreover, little is known about predictors of overweight and obesity in old age. Thus, the purpose of this study was: To present data on the prevalence ... Read more >>

BMC Geriatr (BMC geriatrics)
[2015, 15:83]

Cited: 14 times

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Incident Subjective Cognitive Decline Does Not Predict Mortality in the Elderly--Results from the Longitudinal German Study on Ageing, Cognition, and Dementia (AgeCoDe).

Susanne Roehr, Tobias Luck, Kathrin Heser, Angela Fuchs, Annette Ernst, Birgitt Wiese, Jochen Werle, Horst Bickel, Christian Brettschneider, Alexander Koppara, Michael Pentzek, Carolin Lange, Jana Prokein, Siegfried Weyerer, Edelgard Mösch, Hans-Helmut König, Wolfgang Maier, Martin Scherer, Frank Jessen, Steffi G Riedel-Heller, ,

<h4>Objective</h4>Subjective cognitive decline (SCD) might represent the first symptomatic representation of Alzheimer's disease (AD), which is associated with increased mortality. Only few studies, however, have analyzed the association of SCD and mortality, and if so, based on prevalent cases. Thus, we investigated incident SCD in memory and mortality.<h4>Methods</h4>Data were derived ... Read more >>

PLoS One (PloS one)
[2016, 11(1):e0147050]

Cited: 7 times

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Mortality in incident dementia - results from the German Study on Aging, Cognition, and Dementia in Primary Care Patients.

S Roehr, T Luck, H Bickel, C Brettschneider, A Ernst, A Fuchs, K Heser, H-H König, F Jessen, C Lange, E Mösch, M Pentzek, S Steinmann, S Weyerer, J Werle, B Wiese, M Scherer, W Maier, S G Riedel-Heller, ,

<h4>Objective</h4>Dementia is known to increase mortality, but the relative loss of life years and contributing factors are not well established. Thus, we aimed to investigate mortality in incident dementia from disease onset.<h4>Method</h4>Data were derived from the prospective longitudinal German AgeCoDe study. We used proportional hazards models to assess the impact ... Read more >>

Acta Psychiatr Scand (Acta psychiatrica Scandinavica)
[2015, 132(4):257-269]

Cited: 10 times

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Implementation of chronic illness care in German primary care practices--how do multimorbid older patients view routine care? A cross-sectional study using multilevel hierarchical modeling.

Juliana J Petersen, Michael A Paulitsch, Karola Mergenthal, Jochen Gensichen, Heike Hansen, Siegfried Weyerer, Steffi G Riedel-Heller, Angela Fuchs, Wolfgang Maier, Horst Bickel, Hans-Helmut König, Birgitt Wiese, Hendrik van den Bussche, Martin Scherer, Anne Dahlhaus, ,

<h4>Background</h4>In primary care, patients with multiple chronic conditions are the rule rather than the exception. The Chronic Care Model (CCM) is an evidence-based framework for improving chronic illness care, but little is known about the extent to which it has been implemented in routine primary care. The aim of this ... Read more >>

BMC Health Serv Res (BMC health services research)
[2014, 14:336]

Cited: 6 times

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A comparison of GP and GDS diagnosis of depression in late life among multimorbid patients - results of the MultiCare study.

Michaela Schwarzbach, Melanie Luppa, Heike Hansen, Hans-Helmut König, Jochen Gensichen, Juliana J Petersen, Gerhard Schön, Birgitt Wiese, Siegfried Weyerer, Horst Bickel, Angela Fuchs, Wolfgang Maier, Hendrik van den Bussche, Martin Scherer, Steffi G Riedel-Heller, ,

<h4>Background</h4>The objective of the study was to compare General Practitioners׳ (GPs) diagnosis of depression and depression diagnosis according to Geriatric Depression Scale (GDS) and to identify potential factors associated with both depression diagnosis methods.<h4>Methods</h4>The data were derived from the baseline wave of the German MultiCare1 study, which is a multicentre, ... Read more >>

J Affect Disord (Journal of affective disorders)
[2014, 168:276-283]

Cited: 6 times

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The costs of dementia from the societal perspective: is care provided in the community really cheaper than nursing home care?

Hans-Helmut König, Hanna Leicht, Christian Brettschneider, Cadja Bachmann, Horst Bickel, Angela Fuchs, Frank Jessen, Mirjam Köhler, Melanie Luppa, Edelgard Mösch, Michael Pentzek, Jochen Werle, Siegfried Weyerer, Birgitt Wiese, Martin Scherer, Wolfgang Maier, Steffi G Riedel-Heller, ,

<h4>Objective</h4>To compare the costs of care for community-dwelling dementia patients with the costs of care for dementia patients living in nursing homes from the societal perspective.<h4>Design</h4>Cross-sectional bottom-up cost of illness study nested within the multicenter German AgeCoDe-cohort.<h4>Setting</h4>Community and nursing homes.<h4>Participants</h4>One hundred twenty-eight community-dwelling dementia patients and 48 dementia patients living ... Read more >>

J Am Med Dir Assoc (Journal of the American Medical Directors Association)
[2014, 15(2):117-126]

Cited: 14 times

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Self-efficacy in multimorbid elderly patients with osteoarthritis in primary care--influence on pain-related disability.

Sven Schulz, Katja Brenk-Franz, Anne Kratz, Juliana J Petersen, Steffi G Riedel-Heller, Ingmar Schäfer, Siegfried Weyerer, Birgitt Wiese, Angela Fuchs, Wolfgang Maier, Horst Bickel, Hans-Helmut König, Martin Scherer, Hendrik van den Bussche, Jochen Gensichen, ,

The impact of self-efficacy on pain-related disability in multimorbid elderly patients in primary care is not known. The aim of our study was to analyze the influence of self-efficacy on the relation between pain intensity and pain-related disability, controlled for age and disease count, in aged multimorbid primary care patients ... Read more >>

Clin Rheumatol (Clinical rheumatology)
[2015, 34(10):1761-1767]

Cited: 4 times

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Predictors of costs in dementia in a longitudinal perspective.

Hanna Leicht, Hans-Helmut König, Nina Stuhldreher, Cadja Bachmann, Horst Bickel, Angela Fuchs, Kathrin Heser, Frank Jessen, Mirjam Köhler, Melanie Luppa, Edelgard Mösch, Michael Pentzek, Steffi Riedel-Heller, Martin Scherer, Jochen Werle, Siegfried Weyerer, Birgitt Wiese, Wolfgang Maier, ,

<h4>Objective</h4>To analyse predictors of costs in dementia from a societal perspective in a longitudinal setting.<h4>Method</h4>Healthcare resource use and costs were assessed retrospectively using a questionnaire in four waves at 6-month intervals in a sample of dementia patients (N = 175). Sociodemographic data, dementia severity and comorbidity at baseline, cognitive impairment and impairment ... Read more >>

PLoS One (PloS one)
[2013, 8(7):e70018]

Cited: 26 times

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Relative impact of multimorbid chronic conditions on health-related quality of life--results from the MultiCare Cohort Study.

Christian Brettschneider, Hanna Leicht, Horst Bickel, Anne Dahlhaus, Angela Fuchs, Jochen Gensichen, Wolfgang Maier, Steffi Riedel-Heller, Ingmar Schäfer, Gerhard Schön, Siegfried Weyerer, Birgitt Wiese, Hendrik van den Bussche, Martin Scherer, Hans-Helmut König, ,

<h4>Background</h4>Multimorbidity has a negative impact on health-related quality of life (HRQL). Previous studies included only a limited number of conditions. In this study, we analyse the impact of a large number of conditions on HRQL in multimorbid patients without preselecting particular diseases. We also explore the effects of these conditions ... Read more >>

PLoS One (PloS one)
[2013, 8(6):e66742]

Cited: 69 times

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A comparative study demonstrated that prevalence figures on multimorbidity require cautious interpretation when drawn from a single database.

Hendrik van den Bussche, Ingmar Schäfer, Birgitt Wiese, Anne Dahlhaus, Angela Fuchs, Jochen Gensichen, Susanne Höfels, Heike Hansen, Hanna Leicht, Daniela Koller, Melanie Luppa, Anna Nützel, Jochen Werle, Martin Scherer, Karl Wegscheider, Gerd Glaeske, Gerhard Schön,

<h4>Objective</h4>We investigated the degree of comparability of the prevalence of chronic diseases and disease combinations in the elderly in two databases comparable with regard to diseases included, sex and age of the patients (65-85 years), and cutoff score for case definition.<h4>Study design and setting</h4>One study is based on chart-supported interviews ... Read more >>

J Clin Epidemiol (Journal of clinical epidemiology)
[2013, 66(2):209-217]

Cited: 30 times

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AD dementia risk in late MCI, in early MCI, and in subjective memory impairment.

Frank Jessen, Steffen Wolfsgruber, Birgitt Wiese, Horst Bickel, Edelgard Mösch, Hanna Kaduszkiewicz, Michael Pentzek, Steffi G Riedel-Heller, Tobias Luck, Angela Fuchs, Siegfried Weyerer, Jochen Werle, Hendrik van den Bussche, Martin Scherer, Wolfgang Maier, Michael Wagner, ,

<h4>Objective</h4>To compare the risk of developing Alzheimer's disease (AD) dementia in late mild cognitive impairment (LMCI), early MCI (EMCI), and subjective memory impairment (SMI) with normal test performance.<h4>Methods</h4>The baseline sample (n = 2892) of the prospective cohort study in nondemented individuals (German Study on Aging, Cognition and Dementia in Primary ... Read more >>

Alzheimers Dement (Alzheimer's & dementia : the journal of the Alzheimer's Association)
[2014, 10(1):76-83]

Cited: 163 times

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Effects of multiple chronic conditions on health care costs: an analysis based on an advanced tree-based regression model.

Hans-Helmut König, Hanna Leicht, Horst Bickel, Angela Fuchs, Jochen Gensichen, Wolfgang Maier, Karola Mergenthal, Steffi Riedel-Heller, Ingmar Schäfer, Gerhard Schön, Siegfried Weyerer, Birgitt Wiese, Hendrik van den Bussche, Martin Scherer, Matthias Eckardt, ,

<h4>Background</h4>To analyze the impact of multimorbidity (MM) on health care costs taking into account data heterogeneity.<h4>Methods</h4>Data come from a multicenter prospective cohort study of 1,050 randomly selected primary care patients aged 65 to 85 years suffering from MM in Germany. MM was defined as co-occurrence of ≥3 conditions from a ... Read more >>

BMC Health Serv Res (BMC health services research)
[2013, 13:219]

Cited: 18 times

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The CERAD neuropsychological assessment battery total score detects and predicts Alzheimer disease dementia with high diagnostic accuracy.

Steffen Wolfsgruber, Frank Jessen, Birgitt Wiese, Janine Stein, Horst Bickel, Edelgard Mösch, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Mirjam Köhler, Cadja Bachmann, Steffi G Riedel-Heller, Martin Scherer, Wolfgang Maier, Michael Wagner, ,

<h4>Objectives</h4>To establish the diagnostic accuracy of the Total Score of the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological assessment battery (CERAD-NP) both for cross-sectional discrimination of Alzheimer disease (AD) dementia and short-term prediction of incident AD dementia.<h4>Design</h4>Longitudinal cohort study with two assessments at a 1.5-year interval.<h4>Setting</h4>Primary care sample ... Read more >>

Am J Geriatr Psychiatry (The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry)
[2014, 22(10):1017-1028]

Cited: 20 times

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Age of major depression onset, depressive symptoms, and risk for subsequent dementia: results of the German study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe).

K Heser, F Tebarth, B Wiese, M Eisele, H Bickel, M Köhler, E Mösch, S Weyerer, J Werle, H-H König, H Leicht, M Pentzek, A Fuchs, S G Riedel-Heller, M Luppa, J Prokein, M Scherer, W Maier, M Wagner, ,

<h4>Background</h4>Whether late-onset depression is a risk factor for or a prodrome of dementia remains unclear. We investigated the impact of depressive symptoms and early- v. late-onset depression on subsequent dementia in a cohort of elderly general-practitioner patients (n = 2663, mean age = 81.2 years).<h4>Method</h4>Risk for subsequent dementia was estimated ... Read more >>

Psychol Med (Psychological medicine)
[2013, 43(8):1597-1610]

Cited: 29 times

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Direct costs associated with depressive symptoms in late life: a 4.5-year prospective study.

Melanie Luppa, Hans-Helmut König, Dirk Heider, Hanna Leicht, Tom Motzek, Georg Schomerus, Steffi G Riedel-Heller,

<h4>Background</h4>Depression in old age is common. Only few studies examined the association of depressive symptoms and direct costs in the elderly in a cross-sectional way. This study aims to investigate prospectively health service use and direct costs over a course of 4.5 years considering also different courses of depressive symptomatology.<h4>Methods</h4>305 ... Read more >>

Int Psychogeriatr (International psychogeriatrics)
[2013, 25(2):292-302]

Cited: 16 times

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Effect of cardiovascular and metabolic disease on cognitive test performance and cognitive change in older adults.

Mirjam Köhler, Matthias Kliegel, Hanna Kaduszkiewicz, Cadja Bachmann, Birgitt Wiese, Horst Bickel, Edelgard Mösch, Siegfried Weyerer, Jochen Werle, Angela Fuchs, Michael Pentzek, Hanna Leicht, Hans-Helmut König, Melanie Luppa, Steffi Riedel-Heller, Frank Jessen, Wolfgang Maier, Martin Scherer, Michael Wagner, ,

<h4>Objectives</h4>To examine the effect of cardiovascular and metabolic diseases on initial cognitive test performance and rate of change in three cognitive measures.<h4>Design</h4>Prospective cohort study.<h4>Setting</h4>General practices in six towns throughout Germany.<h4>Participants</h4>Three thousand three hundred twenty-seven participants aged 75 and older (average 79.7 ± 3.6).<h4>Measurements</h4>Data were collected during home visits every 18 ... Read more >>

J Am Geriatr Soc (Journal of the American Geriatrics Society)
[2012, 60(7):1286-1291]

Cited: 10 times

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The assessment of changes in cognitive functioning in the elderly: age- and education-specific reliable change indices for the SIDAM.

Janine Stein, Melanie Luppa, Wolfgang Maier, Franziska Tebarth, Kathrin Heser, Martin Scherer, Thomas Zimmermann, Marion Eisele, Horst Bickel, Edelgard Mösch, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Birgitt Wiese, Jana Prokein, Hans-Helmut König, Hanna Leicht, Steffi G Riedel-Heller, ,

BACKGROUND/AIMS: The diagnostic criteria for dementia include reliable evidence of cognitive deterioration over time measured by cognitive tests. The Structured Interview for the Diagnosis of Dementia of the Alzheimer Type, Multi-infarct Dementia and Dementia of other Etiology according to DSM-III-R, DSM-IV and ICD-10 (SIDAM) is a neuropsychological instrument to determine ... Read more >>

Dement Geriatr Cogn Disord (Dementia and geriatric cognitive disorders)
[2012, 33(2-3):73-83]

Cited: 7 times

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Prediction of incident dementia: impact of impairment in instrumental activities of daily living and mild cognitive impairment-results from the German study on ageing, cognition, and dementia in primary care patients.

Tobias Luck, Melanie Luppa, Birgit Wiese, Wolfgang Maier, Hendrik van den Bussche, Marion Eisele, Frank Jessen, Dagmar Weeg, Siegfried Weyerer, Michael Pentzek, Hanna Leicht, Mirjam Koehler, Franziska Tebarth, Julia Olbrich, Sandra Eifflaender-Gorfer, Angela Fuchs, Hans-Helmut Koenig, Steffi G Riedel-Heller, ,

<h4>Objectives</h4>There is an increasing call for a stronger consideration of impairment in instrumental activities of daily living (IADL) in the diagnostic criteria of Mild Cognitive Impairment (MCI) to improve the prediction of dementia. Thus, the aim of the study was to determine the predictive capability of MCI and IADL impairment ... Read more >>

Am J Geriatr Psychiatry (The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry)
[2012, 20(11):943-954]

Cited: 22 times

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