Full Text Journal Articles by
Author Hajime Kinoshita

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Endovascular treatment for mycotic aneurysm using pyoktanin- applied devices.

Kei Kazuno, Hajime Kinoshita, Mariko Hori, Takamichi Yosizaki, Atsusi Tamura, Hiroshige Sato, Seiichiro Murata,

BACKGROUND:Mycotic thoracic aortic aneurysm is an extremely rare but serious disease because it can easily rupture and has a high mortality rate. The standard therapy for it comprises graft replacement and debridement using systemic antibiotics; nonetheless, this has a high mortality rate and complications. Endovascular aortic repair is considered a ... Read more >>

CVIR Endovasc (CVIR endovascular)
[2020, 3(1):55]

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[Thoracic Endovascular Aortic Repair and Abdominal Aorta Replacement to Treat Stanford Type B Acute Aortic Dissection Extending through an Abdominal Aortic Aneurysm;Report of a Case].

Seiichiro Wariishi, Eiki Fujimoto, Masashi Kano, Hajime Kinoshita, Fumio Chikugo,

A 69-year-old man developed sudden-onset chest and back pain and was brought to our hospital. Enhanced computed tomography (CT) revealed acute Stanford type B aortic dissection extending from the distal aortic arch to a 72 mm abdominal aortic aneurysm( AAA). The acute phase was managed by antihypertensive therapy, and the ... Read more >>

Kyobu Geka (Kyobu geka. The Japanese journal of thoracic surgery)
[2020, 73(6):449-452]

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[Resection of Anterior Mediastinal Tumor Followed by Left Brachiocephalic Vein Reconstruction;Report of a Case].

Seiichiro Wariishi, Toshiyuki Hirose, Keisuke Fujimoto, Hiroyuki Sumitomo, Masashi Kano, Hajime Kinoshita, Fumio Chikugo,

A 65-year-old man was referred to our hospital because of an abnormal shadow on a chest radiogram. Swelling of the face and upper limbs were noted. Enhanced computed tomography showed a 62×101 mm mass in the anterior mediastinum with invasion to the superior vena cava (SVC) and the right upper ... Read more >>

Kyobu Geka (Kyobu geka. The Japanese journal of thoracic surgery)
[2020, 73(5):384-387]

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[Emergent Endovascular Treatment of Spontaneous Rupture of the Thoracic Aorta].

Hajime Kinoshita, Mariko Hori, Atsushi Tamura, Kei Kazuno, Hiroshige Sato, Seiichiro Murata,

Spontaneous rupture of the thoracic aorta is a rare disease with a poor prognosis without obvious trauma, aortic aneurysm and aortic dissection. We report 2 cases of successful endovascular aortic repair for spontaneous rupture of the thoracic aorta. Case 1:A 79-year-old man was referred to our hospital complaining of general ... Read more >>

Kyobu Geka (Kyobu geka. The Japanese journal of thoracic surgery)
[2019, 72(12):984-987]

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[Concomitant Atrial Septal Defect Closure and Repair of Pectus Excavatum in a 50-year-old Patient;Report of a Case].

Atsushi Tamura, Hajime Kinoshita, Kei Kazuno, Hiroshige Sato, Seiichiro Murata, Hiroshi Iida,

We report a case of atrial septal defect (ASD) with severe pectus excavatum. A 50-year-old female had a stroke due to paradoxical embolism from deep vein thrombosis thorough ASD. Her preoperative computed tomography(CT) revealed a severe pectus excavatum (Haller CT index 28.6). The patient underwent ASD closure and repair of ... Read more >>

Kyobu Geka (Kyobu geka. The Japanese journal of thoracic surgery)
[2018, 71(5):380-383]

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Effects of Transplanted Human Cord Blood-Mononuclear Cells on Pulmonary Hypertension in Immunodeficient Mice and Their Distribution.

Mikio Sugano, Homare Yoshida, Hirotsugu Kurobe, Hiroki Arase, Hajime Kinoshita, Takashi Kitaichi, Noriko Sugasawa, Soichiro Nakayama, Kazuhisa Maeda, Minoru Irahara, Tetsuya Kitagawa,

To investigate the effects of human umbilical cord blood-derived mononuclear cell (hUCB-MNC) transplantation on pulmonary hypertension (PH) induced by monocrotaline (MCT) in immunodeficient mice and their distribution.MCT was administered to BALB/c Slc-nu/nu mice, and PH was induced in mice 4 weeks later. Fresh hUCB-MNCs harvested from a human donor after ... Read more >>

J. Med. Invest. (The journal of medical investigation : JMI)
[2017, 64(1.2):43-49]

Cited: 1 time

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PPAR-γ agonist attenuates inflammation in aortic aneurysm patients.

Tatsuo Motoki, Hirotsugu Kurobe, Yoichiro Hirata, Taisuke Nakayama, Hajime Kinoshita, Kevin A Rocco, Hitoshi Sogabe, Takaki Hori, Masataka Sata, Tetsuya Kitagawa,

Peroxisome proliferator-activated receptor (PPAR) -γ agonist, which is an anti-diabetes drug and reduces expression of tumor necrosis factor (TNF)-α, reported to have the effects for anti-inflammation in our body. In cardiovascular fields, this PPAR-γ agonist already reported to suppress progression of coronary atherosclerosis. Various cytokines, which is secreted from fat ... Read more >>

Gen Thorac Cardiovasc Surg (General thoracic and cardiovascular surgery)
[2015, 63(10):565-571]

Cited: 11 times

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Efficacy and Optimal Timing of Endovascular Treatment for Type B Aortic Dissection.

Hajime Kinoshita, Eiki Fujimoto, Hiroki Arase, Hirotsugu Kurobe, Fumio Chikugo, Hitoshi Sogabe, Takashi Kitaichi, Tetsuya Kitagawa,

OBJECTIVES:To determine the efficacy and the optimal timing of thoracic endovascular aortic repair (TEVAR) for closing the primary entry in uncomplicated patients with chronic type B aortic dissection and a patent false lumen (FL). METHODS:Thirteen patients underwent TEVAR for aortic dissection between 2008 and 2012. These patients had chronic dissection ... Read more >>

(Annals of vascular diseases)
[2015, 8(4):307-313]

Cited: 3 times

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Structure and properties of binder gels formed in the system Mg(OH)2-SiO2-H2O for immobilisation of Magnox sludge.

Sam A Walling, Hajime Kinoshita, Susan A Bernal, Nick C Collier, John L Provis,

A cementitious system for the immobilisation of magnesium rich Magnox sludge was produced by blending an Mg(OH)2 slurry with silica fume and an inorganic phosphate dispersant. The Mg(OH)2 was fully consumed after 28 days of curing, producing a disordered magnesium silicate hydrate (M-S-H) with cementitious properties. The structural characterisation of ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2015, 44(17):8126-8137]

Cited: 3 times

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Extraction of Mg(OH)2 from Mg silicate minerals with NaOH assisted with H2O: implications for CO2 capture from exhaust flue gas.

Silvia Madeddu, Michael Priestnall, Erik Godoy, R Vasant Kumar, Sugat Raymahasay, Michael Evans, Ruofan Wang, Seabelo Manenye, Hajime Kinoshita,

The utilisation of Mg(OH)2 to capture exhaust CO2 has been hindered by the limited availability of brucite, the Mg(OH)2 mineral in natural deposits. Our previous study demonstrated that Mg(OH)2 can be obtained from dunite, an ultramafic rock composed of Mg silicate minerals, in highly concentrated NaOH aqueous systems. However, the ... Read more >>

Faraday Discuss (Faraday discussions)
[2015, 183:369-387]

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[Reconstruction of pulmonary blood flow in the Norwood procedure; Blalock-Taussig shunt; from bench to surgery].

Takashi Kitaichi, Mikio Sugano, Hajime Kinoshita, Taisuke Nakayama, Hirotsugu Kurobe, Tamotsu Kanbara, Eiki Fujimoto, Tetsuya Kitagawa,

Although the right-ventricle to pulmonary artery( RV-PA) shunt as a source of pulmonary blood supply of Norwood procedure has improved early outcomes, disadvantages including right ventricular dysfunction or arrhythmias have been reported. So it has been still remained controversial whether BT shunt or RV-PA conduit should be selected. We examined ... Read more >>

Kyobu Geka (Kyobu geka. The Japanese journal of thoracic surgery)
[2014, 67(4):274-277]

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Iliac access conduit facilitates endovascular aortic aneurysm repair and ipsilateral iliofemoral bypass.

Hajime Kinoshita, Eiki Fujimoto, Hitoshi Sogabe, Hiroshi Fujita, Taisuke Nakayama, Mikio Sugano, Hirotsugu Kurobe, Tamotsu Kanbara, Takashi Kitaichi, Tetsuya Kitagawa,

It may be difficult to access a route to deliver a stent-graft for abdominal aortic aneurysm in high-risk patients with bilateral iliofemoral occlusive disease. These two patients underwent both endovascular aortic aneurysm repair by a modified iliac access conduit technique and sequential ipsilateral iliofemoral artery bypass using the conduit, which ... Read more >>

J. Med. Invest. (The journal of medical investigation : JMI)
[2014, 61(1-2):204-207]

Cited: 0 times

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Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodelling.

Taisuke Nakayama, Hirotsugu Kurobe, Noriko Sugasawa, Hajime Kinoshita, Mayuko Higashida, Yuki Matsuoka, Yasushi Yoshida, Yoichiro Hirata, Mie Sakata, Mark W Maxfield, Michio Shimabukuro, Yousuke Takahama, Masataka Sata, Toshiaki Tamaki, Tetsuya Kitagawa, Shuhei Tomita,

AIMS: Excessive vascular remodelling leads to progression of a wide range of vasculopathies, and the immune response to intimal injuries is crucial in this process. This vascular remodelling occurs in the hypoxic microenvironment and is closely related to the immune system. Macrophages play a key role in immunological-cell-mediated arterial remodelling. ... Read more >>

Cardiovasc. Res. (Cardiovascular research)
[2013, 99(4):705-715]

Cited: 20 times

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Delayed-onset severe heparin-induced thrombocytopenia after total arch replacement under cardiopulmonary bypass.

Taisuke Nakayama, Hajime Kinoshita, Mikio Sugano, Hirotsugu Kurobe, Tamotsu Kanbara, Eiki Fujimoto, Takashi Kitaichi, Hiroshi Fujita, Hitoshi Sogabe, Tetsuya Kitagawa,

An extremely rare case with delayed-onset heparin-induced thrombocytopenia (HIT) is described. A 46-year-old man underwent arch replacement for aortic dissection under cardiopulmonary bypass and initial exposure of unfractionated heparin. In post operative 7 days, persistent atrial fibrillation was occurred, so a continuous infusion of heparin (10000 IU/day) and Vitamine K ... Read more >>

J. Med. Invest. (The journal of medical investigation : JMI)
[2013, 60(1-2):154-158]

Cited: 0 times

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Autologous peripheral blood-derived mononuclear cells induced by erythropoietin improve critical ischemic limbs.

Tamotsu Kanbara, Hirotsugu Kurobe, Takashi Kitaichi, Mikio Sugano, Taisuke Nakayama, Hajime Kinoshita, Takashi Iwase, Masafumi Akaike, Masahiro Abe, Masataka Sata, Toshio Matsumoto, Tetsuya Kitagawa,

PURPOSE:Efficient and secure collection of CD34+ cells are crucial for the angiogenic therapies. We have developed autologous peripheral blood-mononuclear cell (MNC) transplantation induced by erythropoietin (rhEPO) for critical ischemic limbs. METHODS:Seven patients, including five with arteriosclerosis obliterans, one with Buerger's disease and one with progressive systemic sclerosis, underwent ten cell ... Read more >>

(Annals of vascular diseases)
[2012, 5(1):52-60]

Cited: 0 times

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Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress.

Hirotsugu Kurobe, Ken-ichi Aihara, Mayuko Higashida, Yoichiro Hirata, Masako Nishiya, Yuki Matsuoka, Tamotsu Kanbara, Taisuke Nakayama, Hajime Kinoshita, Mikio Sugano, Eiki Fujimoto, Ayako Kurobe, Noriko Sugasawa, Takashi Kitaichi, Masashi Akaike, Masataka Sata, Toshio Matsumoto, Tetsuya Kitagawa,

AIM:Ezetimibe, an inhibitor of cholesterol intestinal absorption, is a lipid lowering agent. However, anti-atherogenic effects of ezetimibe have not been fully elucidated. Therefore, the objective in this study was to clarify the vascular protective effects of ezetimibe in patients with hypercholesterolemia. METHODS:Ezetimibe was administered to 20 patients with hypercholesterolemia (group ... Read more >>

J. Atheroscler. Thromb. (Journal of atherosclerosis and thrombosis)
[2011, 18(12):1080-1089]

Cited: 10 times

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In situ spectroscopy and spectroelectrochemistry of uranium in high-temperature alkali chloride molten salts.

Ilya B Polovov, Vladimir A Volkovich, John M Charnock, Brett Kralj, Robert G Lewin, Hajime Kinoshita, Iain May, Clint A Sharrad,

Soluble uranium chloride species, in the oxidation states of III+, IV+, V+, and VI+, have been chemically generated in high-temperature alkali chloride melts. These reactions were monitored by in situ electronic absorption spectroscopy. In situ X-ray absorption spectroscopy of uranium(VI) in a molten LiCl-KCl eutectic was used to determine the ... Read more >>

Inorg Chem (Inorganic chemistry)
[2008, 47(17):7474-7482]

Cited: 5 times

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Molecular cloning and functional analyses of OAT1 and OAT3 from cynomolgus monkey kidney.

Harunobu Tahara, Masayuki Shono, Hiroyuki Kusuhara, Hajime Kinoshita, Eiichi Fuse, Akira Takadate, Masaki Otagiri, Yuichi Sugiyama,

The functional characterization of monkey OAT1 (SLC22A6) and OAT3 (SLC22A8) was carried out to elucidate species differences in the OAT1- and OAT3-mediated transport between monkey and human.The cDNAs of monkey OAT1 and OAT3 were isolated from monkey kidney, and their stable transfectants were established in HEK293 cells (mkOAT1- and mkOAT3-HEK). ... Read more >>

Pharm. Res. (Pharmaceutical research)
[2005, 22(4):647-660]

Cited: 32 times

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Uranium oligomerization in chloride-based high temperature melts: in situ XAS studies.

Anand I Bhatt, Erwan du Fou de Kerdaniel, Hajime Kinoshita, Francis R Livens, Iain May, Ilya B Polovov, Clint A Sharrad, Vladimir A Volkovich, John M Charnock, Robert G Lewin,

In situ EXAFS spectroscopic studies of uranium compounds in high temperature alkali chloride melts indicate the presence of oligomeric species. An investigation into UCl(3) and UCl(4) dissolved in LiCl reveals long range ordering of uranium atoms in the molten state which is not maintained on quenching. Studies of uranium dioxide ... Read more >>

Inorg Chem (Inorganic chemistry)
[2005, 44(1):2-4]

Cited: 1 time

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