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Author Correction: A quantitative method for proteome reallocation using minimal regulatory interventions.

Gustavo Lastiri-Pancardo, Jonathan S Mercado-Hernández, Juhyun Kim, José I Jiménez, José Utrilla,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nat Chem Biol (Nature chemical biology)
[2020, 16(11):1277]

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A quantitative method for proteome reallocation using minimal regulatory interventions.

Gustavo Lastiri-Pancardo, Jonathan S Mercado-Hernández, Juhyun Kim, José I Jiménez, José Utrilla,

Engineering resource allocation in biological systems is an ongoing challenge. Organisms allocate resources for ensuring survival, reducing the productivity of synthetic biology functions. Here we present a new approach for engineering the resource allocation of Escherichia coli by rationally modifying its transcriptional regulatory network. Our method (ReProMin) identifies the minimal ... Read more >>

Nat. Chem. Biol. (Nature chemical biology)
[2020, 16(9):1026-1033]

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A quantitative method for proteome reallocation using minimal regulatory interventions

Gustavo Lastiri-Pancardo, J.S Mercado-Hernandez, Juhyun Kim, José Jiménez, José Utrilla,

Abstract Engineering resource allocation in biological systems for synthetic biology applications is an ongoing challenge. Wild type organisms allocate abundant cellular resources for ensuring survival in changing environments, reducing the productivity of engineered functions. Here we present a novel approach for engineering the resource allocation of Escherichia coli by rationally ... Read more >>

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