Full Text Journal Articles by
Author Guohong Tian

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Pseudotumour Cerebri Syndrome in China: A Cohort Study.

Qian Chen, Chaoyi Feng, Guixian Zhao, Weimin Chen, Min Wang, Xinghuai Sun, Yan Sha, Zhenxin Li, Guohong Tian,

Pseudotumour cerebri syndrome (PTCS) remains to be fully investigated in Chinese patients and our study reported PTCS-related clinical differences between Chinese patients and Western patients. This study enrolled 55 consecutive patients (females: 44, median age: 37 y, age range: 14-62 y) with PTCS diagnosed from October 2015 to December 2017. Nine (16.4%, ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):1222]

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Role of Diffusional Kurtosis Imaging in Differentiating Neuromyelitis Optica-Related and Multiple Sclerosis-Related Acute Optic Neuritis: Comparison With Diffusion-Weighted Imaging.

Ping Lu, Ting Yuan, Xilan Liu, Guohong Tian, Jibin Zhang, Yan Sha,

PURPOSE:The discrimination between neuromyelitis optica (NMO)- and multiple sclerosis (MS)-related acute optic neuritis (ON) after the first presentation is difficult in clinical practice. Through a comparison with diffusion-weighted imaging using readout-segmented echo-planar imaging (RESOLVE-DWI), our aim was to determine the feasibility of diffusional kurtosis imaging (DKI) for differential diagnosis. MATERIALS ... Read more >>

J Comput Assist Tomogr (Journal of computer assisted tomography)
[2020, 44(1):47-52]

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Novel mutations and the ophthalmologic characters in Chinese patients with Wolfram Syndrome.

Youjia Zhang, Lili Feng, Xiangmei Kong, Jihong Wu, Yuhong Chen, Guohong Tian,

BACKGROUND:Wolfram Syndrome (WFS) is a rare autosomal recessive neurodegenerative disease which has a wide spectrum of manifestations including diabetes insipidus, diabetes mellitus, optic atrophy and deafness. WFS1 and CISD2 are two main causing genes of WFS. The aim of this study was to illustrate the ophthalmologic manifestations and determine the ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2019, 14(1):190]

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Giant cell arteritis presenting as bilateral anterior ischemic optic neuropathy: a biopsy-proven case report in Chinese patient.

Guohong Tian, Weimin Chen, Qian Chen, Min Wang, Guixian Zhao, Zhenxin Li, Jiong Zhang,

BACKGROUND:Giant cell arteritis (GCA) is a systemic vasculitis of medium and large-size vessels and can led to permanent visual loss in elderly patients. GCA is very rare among Asians. We report a Chinese patient presenting with acute bilateral anterior ischemic optic neuropathy, and the temporal artery biopsy proved the diagnose ... Read more >>

BMC Ophthalmol (BMC ophthalmology)
[2018, 18(1):282]

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Differentiating Neuromyelitis Optica-Related and Multiple Sclerosis-Related Acute Optic Neuritis Using Conventional Magnetic Resonance Imaging Combined With Readout-Segmented Echo-Planar Diffusion-Weighted Imaging.

Ping Lu, Guohong Tian, Xilan Liu, Feng Wang, Zhongshuai Zhang, Yan Sha,

In clinical practice, acute optic neuritis (ON) associated with the development of neuromyelitis optica (NMO) after the first attack is often indistinguishable from that associated with multiple sclerosis (MS). We aimed to determine the optimal combination of features derived from conventional magnetic resonance imaging (MRI) and diffusion-weighted imaging using readout-segmented ... Read more >>

J Comput Assist Tomogr (Journal of computer assisted tomography)
[2018, 42(4):502-509]

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Clinical Characteristics of Pediatric Optic Neuritis With Myelin Oligodendrocyte Glycoprotein Seropositive: A Cohort Study.

Qian Chen, Guixian Zhao, Yongheng Huang, Zhenxin Li, Xinghuai Sun, Ping Lu, Yan San, Min Wang, Guohong Tian,

BACKGROUND:The clinical characteristics of patients with pediatric optic neuritis with seropositive myelin oligodendrocyte glycoprotein antibodies in Asia have not been reported. METHODS:Patients ≤18 years-old with acute-onset optic neuritis were enrolled. Serum myelin oligodendrocyte glycoprotein and aquaporin-4 antibodies were detected and patients were followed for at least six months. The clinical features ... Read more >>

Pediatr. Neurol. (Pediatric neurology)
[2018, 83:42-49]

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Analysis of Genetic Mutations in a Cohort of Hereditary Optic Neuropathy in Shanghai, China.

Dekang Gan, Mengwei Li, Jihong Wu, Xinghuai Sun, Guohong Tian,

To evaluate the clinical classification and characteristics of hereditary optic neuropathy patients in a single center in China.Retrospective case study. Patients diagnosed with hereditary optic neuropathy between January 2014 and December 2015 in the neuro-ophthalmology division in Shanghai Eye and ENT Hospital of Fudan University were recruited. Clinical features as ... Read more >>

J Ophthalmol (Journal of ophthalmology)
[2017, 2017:6186052]

Cited: 1 time

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Clinical characteristics of myelin oligodendrocyte glycoprotein seropositive optic neuritis: a cohort study in Shanghai, China.

Guixian Zhao, Qian Chen, Yongheng Huang, Zhenxin Li, Xinghuai Sun, Ping Lu, S Yan, Min Wang, Guohong Tian,

Qualitative and quantitative visual outcomes of Asian optic neuritis (ON) patients with seropositive myelin oligodendrocyte glycoprotein (MOG) antibodies remain unknown. We retrospectively evaluated a cohort of new-onset ON patients in Shanghai, China between January 2015 and December 2016. Serum MOG and aquaporin-4 (AQP4) antibodies were detected using cell-based assays, and ... Read more >>

J. Neurol. (Journal of neurology)
[2018, 265(1):33-40]

Cited: 6 times

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Assessment of nonarteritic anterior ischemic optic neuropathy with intravoxel incoherent motion diffusion-weighted imaging using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition.

Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tian, Wenlin Tang,

PURPOSE:To determine the feasibility of intravoxel incoherent motion (IVIM) for characterizing perfusion properties and its potential diagnostic utility for nonarteritic anterior ischemic optic neuropathy (NAION). IVIM diffusion-weighted imaging is a promising technique that can measure perfusion and diffusion characteristics simultaneously in a noninvasive manner. MATERIALS AND METHODS:Orbital IVIM in a ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2017, 46(6):1760-1766]

Cited: 3 times

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High-resolution transbulbar ultrasonography helping differentiate intracranial hypertension in bilateral optic disc oedema patients.

Qian Chen, Weimin Chen, Min Wang, Xinghuai Sun, Yan Sha, Zhenxin Li, Guohong Tian,

The enlargement of optic nerve sheath diameter (ONSD) has been proven to be related with raised intracranial pressure (ICP). No prospective study has been focused on utilizing retrobulbar ultrasonography in optic disc oedema patient presented to ophthalmologist.High-resolution transbulbar ultrasonography was performed in a cohort of patient presented with bilateral optic ... Read more >>

Acta Ophthalmol (Acta ophthalmologica)
[2017, 95(6):e481-e485]

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Role of coronal high-resolution diffusion-weighted imaging in acute optic neuritis: a comparison with axial orientation.

Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tian,

Through a comparison with the axial orientation, we aimed to evaluate the role of coronal high-resolution diffusion-weighted imaging (DWI) in acute optic neuritis based on diagnostic accuracy and the reproducibility of apparent diffusion coefficient (ADC) measurements.Orbital DWI, using readout-segmented, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-DWI), was performed on 49 ... Read more >>

Neuroradiology (Neuroradiology)
[2017, 59(8):737-745]

Cited: 3 times

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Takayasu arteritis presenting as isolated anterior ischemic optic neuropathy.

Guohong Tian, Qian Chen, Wenji Wang,

Takayasu arteritis (TA) is a systemic vasculitis of unknown etiology that affects the aorta and its primary branches or large arteries in the proximal upper or lower extremities. Ocular manifestations of TA include microaneurysm formation, small-vessel dilation, arteriovenous anastomosis, retinal ischemia, and neovascular glaucoma. We herein report a case involving ... Read more >>

Int Ophthalmol (International ophthalmology)
[2018, 38(2):823-828]

Cited: 0 times

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Diffusion-weighted imaging helps differentiate multiple sclerosis and neuromyelitis optica-related acute optic neuritis.

Hailin Wan, Huijin He, Fang Zhang, Yan Sha, Guohong Tian,

PURPOSE:To evaluate the apparent diffusion coefficient (ADC) values between multiple sclerosis (MS) and neuromyelitis optica (NMO)-related acute optic neuritis (ON) patients and predict their optic nerve atrophy of optic coherence tomography (OCT) parameters. MATERIALS AND METHODS:Nineteen MS and 15 NMO-related acute ON patients who underwent a diffusion-weighted imaging sequence in ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2017, 45(6):1780-1785]

Cited: 3 times

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Fundus autofluorescence and optical coherence tomography of a macular cherry-red spot in a case report of sialidosis.

Wenjun Zou, Xin Wang, Guohong Tian,

Sialidosis is a rare lysosomal storage disorder characterized by deficiency of alpha-N-acetyl neuraminidase. The macular cherry-red spot, which could be important for diagnosis, is a distinctive feature of its ocular manifestation. We evaluated the fundus autofluorescence (FAF) and optical coherence tomography (OCT) images of a juvenile patient who presented with ... Read more >>

BMC Ophthalmol (BMC ophthalmology)
[2016, 16:30]

Cited: 1 time

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Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort.

Guohong Tian, Zhenxin Li, Guixian Zhao, Chaoyi Feng, Mengwei Li, Yongheng Huang, Xinghuai Sun,

We evaluate a cohort of optic neuritis and neuromyelitis optica (NMO) spectrum disorders patients in a territory hospital in China. The peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (GCC) were measured using spectral-domain OCT after 6 months of acute onset. The results showed that both the ... Read more >>

J Ophthalmol (Journal of ophthalmology)
[2015, 2015:832784]

Cited: 4 times

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Lesion Activity on Brain MRI in a Chinese Population with Unilateral Optic Neuritis.

Chuntao Lai, Qinglin Chang, Guohong Tian, Jiawei Wang, Hongxia Yin, Wu Liu,

Longitudinal studies have shown that brain white matter lesions are strong predictors of the conversion of unilateral optic neuritis to multiple sclerosis (MS) in Caucasian populations. Consequently brain MRI criteria have been developed to improve the prediction of the development of clinically definite multiple sclerosis (CDMS). In Asian populations, optic ... Read more >>

PLoS ONE (PloS one)
[2015, 10(10):e0141005]

Cited: 1 time

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Diffusion-weighted imaging using readout-segmented echo-planar imaging, parallel imaging, and two-dimensional navigator-based reacquisition in detecting acute optic neuritis.

Hailin Wan, Yan Sha, Fang Zhang, Rujian Hong, Guohong Tian, Heng Fan,

To evaluate the accuracy of diffusion-weighted imaging (DWI) in comparison to contrast-enhanced, fat-suppressed T1 -weighted imaging (CET1WI) in detecting acute optic neuritis (ON).The clinical data and magnetic resonance imaging (MRI) findings of 42 patients who presented with decreased vision were retrospectively reviewed. Both 3.0T MRI DWI and CET1WI orbital imaging ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2016, 43(3):655-660]

Cited: 8 times

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Papilledema as the initial presentation of Castleman disease.

Guohong Tian, Yun Jing, Hanqiu Jiang, Jingwen Wang, Xiaojun Zhang,

Castleman disease is a rare lymphoproliferative disorder that has many presentations ranging from unifocal or multifocal mass lesions to a monoclonal gammopathy. It has features that may overlap with osteosclerotic myeloma or POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes) syndrome. We report a patient with papilledema, enlarged lymph nodes, ... Read more >>

J Neuroophthalmol (Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society)
[2014, 34(2):169-172]

Cited: 1 time

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Intracranial pressure fluctuations: a potential risk factor for glaucoma?

Zheng Zhang, Xiaolei Wang, Jost B Jonas, Huaizhou Wang, Xiaojun Zhang, Xiaoxia Peng, Robert Ritch, Guohong Tian, Diya Yang, Lei Li, Junfa Li, Ningli Wang,

Acta Ophthalmol (Acta ophthalmologica)
[2015, 93(1):e84-5]

Cited: 2 times

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Valsalva manoeuver, intra-ocular pressure, cerebrospinal fluid pressure, optic disc topography: Beijing intracranial and intra-ocular pressure study.

Zheng Zhang, Xiaolei Wang, Jost B Jonas, Huaizhou Wang, Xiaojun Zhang, Xiaoxia Peng, Robert Ritch, Guohong Tian, Diya Yang, Lei Li, Junfa Li, Ningli Wang,

PURPOSE: To assess whether a Valsalva manoeuver influences intra-ocular pressure (IOP), cerebrospinal fluid pressure (CSF-P) and, by a change in the trans-laminar cribrosa pressure difference, optic nerve head morphology. METHODS: In the first part of the study, 20 neurological patients (study group 'A') underwent measurement of IOP and lumbar CSF-P ... Read more >>

Acta Ophthalmol (Acta ophthalmologica)
[2014, 92(6):e475-80]

Cited: 28 times

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Noninvasive intracranial pressure estimation by orbital subarachnoid space measurement: the Beijing Intracranial and Intraocular Pressure (iCOP) study.

Xiaobin Xie, Xiaojun Zhang, Jidi Fu, Huaizhou Wang, Jost B Jonas, Xiaoxia Peng, Guohong Tian, Junfang Xian, Robert Ritch, Lei Li, Zefeng Kang, Shoukang Zhang, Diya Yang, Ningli Wang, ,

INTRODUCTION: The orbital subarachnoid space surrounding the optic nerve is continuous with the circulation system for cerebrospinal fluid (CSF) and can be visualized by using magnetic resonance imaging (MRI). We hypothesized that the orbital subarachnoid space width (OSASW) is correlated with and can serve as a surrogate for intracranial pressure ... Read more >>

Crit Care (Critical care (London, England))
[2013, 17(4):R162]

Cited: 41 times

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Central retinal artery occlusion and recurrent papillitis in a patient with incomplete Behçet disease.

Guohong Tian, Ning Lu, Rong Yan, Xiaojun Zhang,

A 40-year-old man presented with painless sudden visual loss due to a central retinal artery occlusion (CRAO) in his right eye. Three months later, he had painless acute visual loss in his left eye with visual acuity of 20/100 and a swollen optic disc. After oral prednisone treatment, the disc ... Read more >>

J Neuroophthalmol (Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society)
[2011, 31(3):244-247]

Cited: 4 times

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Cerebrospinal fluid pressure correlated with body mass index.

Ruojin Ren, Ningli Wang, Xiaojun Zhang, Guohong Tian, Jost B Jonas,

Graefes Arch. Clin. Exp. Ophthalmol. (Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie)
[2012, 250(3):445-446]

Cited: 22 times

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Neuromyelitis optica antibodies in patients with severe optic neuritis in China.

Chuntao Lai, Guohong Tian, Toshiyuki Takahashi, Wu Liu, Ling Yang, Xiaojun Zhang,

BACKGROUND: Severe visual loss is seen in both multiple sclerosis-associated optic neuritis (ON) and neuromyelitis optica (NMO)-associated ON. NMO (aquaporin 4) antibodies have been reported to have diagnostic and prognostic value for visual and neurological outcomes of recurrent ON. We performed this study to investigate the frequency of NMO antibodies ... Read more >>

J Neuroophthalmol (Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society)
[2011, 31(1):16-19]

Cited: 15 times

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Clinical characteristics, therapeutic outcomes of isolated atypical optic neuritis in China.

Chuntao Lai, Guohong Tian, Wu Liu, Wenbing Wei, Toshiyuki Takahashi, Xiaojun Zhang,

BACKGROUND/AIM: The causes of atypical optic neuritis are different from typical demyelinating optic neuritis. It may exist as an isolated entity or may be part of a systemic process. Our aim was to determine the clinical characteristics, and therapeutic outcomes of isolated atypical optic neuritis in China. METHODS: Inclusion criteria ... Read more >>

J. Neurol. Sci. (Journal of the neurological sciences)
[2011, 305(1-2):38-40]

Cited: 7 times

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