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Author Gunay Can

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Factors affecting mortality in geriatric patients hospitalized with COVID-19

Rabia Bağ Soytaş, Damla Ünal, Pınar Arman, Veysel Suzan, Tuğçe Emiroğlu Gedik, Günay Can, Bora Korkmazer, Rıdvan Karaali, Şermin Börekçi, Mert Ahmet Kuşkucu, Hakan Yavuzer, Deniz Suna Erdinçler, Alper Döventaş,

<h4>Background/aim</h4>We aimed to investigate the factors affecting the mortality of patients aged 65 years or older who were hospitalized with the diagnosis of new coronavirus pneumonia (COVID-19).<h4>Materials and methods</h4>This is a retrospective study of patients 65 years old or older with COVID-19 who were hospitalized in İstanbul University-Cerrahpaşa, Cerrahpaşa Medical ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2021, 51(2):454-463]

Cited: 1 time

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Inactive SARS-CoV-2 vaccine generates high antibody responses in healthcare workers with and without prior infection.

Harika Oyku Dinc, Nese Saltoglu, Gunay Can, Ilker Inanc Balkan, Beyhan Budak, Dogukan Ozbey, Bilge Caglar, Rıdvan Karaali, Bilgul Mete, Yesim Tuyji Tok, Yagmur Ersoy, Mert Ahmet Kuskucu, Kenan Midilli, Sevgi Ergin, Bekir Sami Kocazeybek,

<h4>Background and objectives</h4>Healthcare workers (HCWs) were among the first groups to be vaccinated in Turkey. The data to be obtained by the vaccination of HCWs would guide wide spread vaccination programs.<h4>Materials and methods</h4>The study included 330 HCWs working at Istanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty Hospital and vaccinated with inactive CoronaVac ... Read more >>

Vaccine (Vaccine)
[2021, :]

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Inactive SARS-CoV-2 vaccine generates high antibody responses in healthcare workers with and without prior infection

Harika Oyku Dinc, Nese Saltoglu, Gunay Can, Ilker Inanc Balkan, Beyhan Budak, Dogukan Ozbey, Bilge Caglar, Rıdvan Karaali, Bilgul Mete, Yesim Tuyji Tok, Yagmur Ersoy, Mert Ahmet Kuskucu, Kenan Midilli, Sevgi Ergin, Bekir Sami Kocazeybek,

<h4>Background and Objectives</h4> Healthcare workers (HCWs) were among the first groups to be vaccinated in Turkey. The data to be obtained by the vaccination of HCWs would guide wide spread vaccination programs. <h4>Materials and Methods</h4> The study included 330 HCWs working at Istanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty Hospital and vaccinated ... Read more >>

Vaccine (Vaccine)
[2021, :]

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COVID-19 Vaccine Hesitancy in Healthcare Personnel: A University Hospital Experience.

Beril Kara Esen, Gunay Can, Betul Zehra Pirdal, Sumeyye Nur Aydin, Aysenur Ozdil, Ilker Inanc Balkan, Beyhan Budak, Yilmaz Keskindemirci, Ridvan Karaali, Nese Saltoglu,

Healthcare workers are among risk groups in the COVID-19. Even if they are not infected with the disease, they witness the effects of the pandemic. The aim of the study is to determine the factors affecting COVID-19 vaccination status and reasons for vaccine hesitancy of healthcare personnel in our hospital. ... Read more >>

Vaccines (Basel) (Vaccines)
[2021, 9(11):]

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Ureteral wall thickness at the stone site: A critical predictor of success and complications in children undergoing semi-rigid ureteroscopy.

Elif Altınay Kırlı, Emre Bülbül, Onur Kaygısız, Sezgin Yeni, Günay Can, Onur Tutar, Bulent Onal,

<h4>Introduction</h4>We retrospectively assessed the role of ureteral wall thickness (UWT) at the ureteral stone site in predicting the stone-free status and the complication rates in children undergoing semi-rigid ureterorenoscopy (URS).<h4>Patients and methods</h4>The children who underwent URS and had undergone non-contrast abdominal computerized tomography before the URS were included in the ... Read more >>

J Pediatr Urol (Journal of pediatric urology)
[2021, :]

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Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.

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<h4>Background</h4>Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.<h4>Methods</h4>We used data from 1990 to 2019 on people aged ... Read more >>

Lancet (Lancet (London, England))
[2021, 398(10304):957-980]

Cited: 4 times

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The Relationship between Pre-Pandemic Interferon Gamma Release Assay Test Results and COVID-19 Infection: Potential Prognostic Value of Indeterminate IFN-γ Release Assay Results.

Sermin Borekci, Fatma Gulsum Karakas, Serhat Sirekbasan, Bahar Kubat, Rıdvan Karaali, Gunay Can, Bekir Sami Kocazeybek, Bilun Gemicioglu,

<h4>Objective</h4>To reveal the relationship between interferon-gamma release assay (IGRA) test (Standard ETB-Feron ELISA (TBF)) results performed within 12 months before the COVID-19 pandemic and the frequency of COVID-19 infections and the severity of COVID-19.<h4>Methods</h4>The retrospective TBF test results and contact information of 684 patients aged over 18 years who underwent ... Read more >>

Can J Infect Dis Med Microbiol (The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale)
[2021, 2021:1989277]

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Relationship between the types of urinary incontinence, handgrip strength, and pelvic floor muscle strength in adult women.

Rabia Bag Soytas, Mustafa Soytas, Yavuz O Danacioglu, Sinharib Citgez, Hakan Yavuzer, Gunay Can, Bulent Onal, Alper Doventas,

<h4>Aim</h4>To investigate the relationship between handgrip strength with types of urinary incontinence (UI) and pelvic floor muscle strength (PFMS) in women.<h4>Methods</h4>Ninety-two women, who presented to the geriatric and urology outpatient clinics complaining of UI between July 2019 and February 2020 and had indicated to undergo urodynamic assessment after basic neurourological ... Read more >>

Neurourol Urodyn (Neurourology and urodynamics)
[2021, 40(6):1532-1538]

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Low Serum Uric Acid Predicts Risk of a Composite Disease Endpoint.

Fatma Özpamuk-Karadeniz, Yusuf Karadeniz, Adnan Kaya, Servet Altay, Günay Can, Altan Onat,

<i>Background and objectives:</i> Mortality may increase in hypouricemia as well as inhyperuricemia. We assessed the predictive value of low serum uric acid (SUA) levels on the risk of overall mortality or a composite endpoint of death and nonfatal events. <i>Materials and Methods:</i> In 1013 community-based middle-aged adults, free of uncontrolled ... Read more >>

Medicina (Kaunas) (Medicina (Kaunas, Lithuania))
[2021, 57(4):]

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Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.

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From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, ... Read more >>

Elife (eLife)
[2021, 10:]

Cited: 5 times

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An easy-to-use nomogram for predicting in-hospital mortality risk in COVID-19: a retrospective cohort study in a university hospital.

Hazal Cansu Acar, Günay Can, Rıdvan Karaali, Şermin Börekçi, İlker İnanç Balkan, Bilun Gemicioğlu, Dildar Konukoğlu, Ethem Erginöz, Mehmet Sarper Erdoğan, Fehmi Tabak,

<h4>Background</h4>One-fifth of COVID-19 patients are seriously and critically ill cases and have a worse prognosis than non-severe cases. Although there is no specific treatment available for COVID-19, early recognition and supportive treatment may reduce the mortality. The aim of this study is to develop a functional nomogram that can be ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2021, 21(1):148]

Cited: 3 times

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The Impact of Stone Density on Operative Complications of Retrograde Intrarenal Surgery: A Multicenter Study with Propensity Score Matching Analysis.

Cem Basatac, Oktay Özman, Hacı Murat Akgül, Onur Ozyaman, Onder Cinar, Günay Can, Eyüp Burak Sancak, Cenk Murat Yazici, Haluk Akpinar,

<b><i>Background:</i></b> The aim of the study was to evaluate the impact of stone density on operative complication rates in retrograde intrarenal surgery (RIRS). <b><i>Materials and Methods:</i></b> A total of 473 consecutive patients undergoing RIRS for the treatment of upper tract urinary stones were included. To adjust for baseline confounders, one-to-one ... Read more >>

J Laparoendosc Adv Surg Tech A (Journal of laparoendoscopic & advanced surgical techniques. Part A)
[2021, :]

Cited: 0 times

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Risk factors predicting upper urinary tract deterioration in children with spinal cord injury.

Bülent Önal, Elif A Kırlı, Berin Selçuk, Derya Buğdaycı, Günay Can, Bülent Çetinel,

<h4>Aim</h4>The aim of this study is to determine the risk factors predicting upper urinary tract (UUT) deterioration in children with spinal cord injury (SCI).<h4>Methods</h4>The medical records of 108 children with SCI who were referred to our unit between 1996 and 2018 were retrospectively reviewed. The data included general patient demographics, ... Read more >>

Neurourol Urodyn (Neurourology and urodynamics)
[2021, 40(1):435-442]

Cited: 0 times

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Interobserver agreement between interpretations of acute changes after lung stereotactic body radiotherapy.

Meltem Dağdelen, Emine Sedef Akovalı, Ceren Barlas, Günay Can, Fazilet Öner Dinçbaş,

<h4>Purpose</h4>Stereotactic body radiation therapy (SBRT) is an effective treatment modality for inoperable early-stage lung cancer or metastatic lung lesions. Post-SBRT, acute radiological lung changes sometimes mimic tumor progression, so over-investigation may be applied. We aimed to reveal the interobserver agreement among physicians regarding acute radiographic changes on CT of the ... Read more >>

Strahlenther Onkol (Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al])
[2021, 197(5):423-428]

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Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.

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<h4>Background</h4>Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents.<h4>Methods</h4>For this pooled analysis, ... Read more >>

Lancet (Lancet (London, England))
[2020, 396(10261):1511-1524]

Cited: 21 times

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Sex-specific associations of TCF7L2 variants with fasting glucose, type 2 diabetes and coronary heart disease among Turkish adults.

Ayşe Berna Yüzbaşıoğulları, Evrim Kömürcü-Bayrak, Altan Onat, Gunay Can, Nina Mononen, Reijo Laaksonen, Mika Kähönen, Terho Lehtimäki, Nihan Erginel-Ünaltuna,

<h4>Objective</h4>TCF7L2 is a repressor and transactivator of genes, and its variants are strongly associated with diabetes. This study aimed to evaluate the sex-specific relationship between the most common TCF7L2 gene variants (-98368G>T, rs12255372 and -47833C>T, rs7903146) with diabetes and coronary heart disease in Turkish Adult Risk Factor (TARF) Study.<h4>Methods</h4>Single nucleotide ... Read more >>

Anatol J Cardiol (Anatolian journal of cardiology)
[2020, 24(5):326-333]

Cited: 0 times

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Change in species distribution and antifungal susceptibility of candidemias in an intensive care unit of a university hospital (10-year experience).

Bilgul Mete, Esra Yerlikaya Zerdali, Gokhan Aygun, Nese Saltoglu, Ilker Inanc Balkan, Ridvan Karaali, Sibel Yildiz Kaya, Berna Karaismailoglu, Abdurrahman Kaya, Seval Urkmez, Gunay Can, Fehmi Tabak, Recep Ozturk,

Candidemia is a nosocomial infection mostly found in critically ill patients. Our objectives were to evaluate the change in distribution and resistance profile of Candida spp. isolated from candidemic patients in our intensive care unit over two 5-year periods spanning 15 years and to evaluate the risk factors. Records from the ... Read more >>

Eur J Clin Microbiol Infect Dis (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2021, 40(2):325-333]

Cited: 2 times

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The rs2175898 Polymorphism in the ESR1 Gene has a Significant Sex-Specific Effect on Obesity.

Filiz Guclu-Geyik, Neslihan Coban, Gunay Can, Nihan Erginel-Unaltuna,

Polymorphisms in the ESR1 gene have been associated with obesity and lipid metabolism. There are also important sex-related differences in the prevalence of obesity and related phenotypes. Therefore, we aimed to interrogate the association of the ESR1 rs2175898 gene polymorphism with obesity, obesity-related variables, and lipid levels in men and ... Read more >>

Biochem Genet (Biochemical genetics)
[2020, 58(6):935-952]

Cited: 2 times

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An eleven-year cohort of bloodstream infections in 552 febrile neutropenic patients: resistance profiles of Gram-negative bacteria as a predictor of mortality.

Ritvan Kara Ali, Serkan Surme, Ilker Inanc Balkan, Ayse Salihoglu, Meryem Sahin Ozdemir, Yusuf Ozdemir, Bilgul Mete, Gunay Can, Muhlis Cem Ar, Fehmi Tabak, Nese Saltoglu,

Antimicrobial stewardship is of major importance in patients with febrile neutropenia (FN). In this study, we aimed to investigate the trends in resistance and the relationship with mortality rates in patients with FN. The single-center surveillance data of inpatients with FN and diagnosed as microbiologically confirmed bloodstream infections (BSIs) between ... Read more >>

Ann Hematol (Annals of hematology)
[2020, 99(8):1925-1932]

Cited: 2 times

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Repositioning of the global epicentre of non-optimal cholesterol.

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High blood cholesterol is typically considered a feature of wealthy western countries<sup>1,2</sup>. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world<sup>3</sup> and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and ... Read more >>

Nature (Nature)
[2020, 582(7810):73-77]

Cited: 15 times

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Independent Prognostic Indicators in the Elderly with Pneumonia: A Single-Center Prospective Observational Study

Serkan Surme, Ilker Inanc Balkan, Osman Faruk Bayramlar, Ritvan Kara Ali, Bilgul Mete, Gunay Can, Fehmi Tabak, Nese Saltoglu,

<h4>Background: </h4> The aim of this study was to investigate poor prognostic indicators in the elderly with pneumonia. <h4>Methods:</h4> In this prospective observational study, the patients with pneumonia were stratified into younger (18-64 years) and older (≥65 years) groups. The poor prognostic indicators were determined and compared. <h4>Results:</h4> There were ... Read more >>

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Excess Mortality in Istanbul during Extreme Heat Waves between 2013 and 2017.

Günay Can, Ümit Şahin, Uğurcan Sayılı, Marjolaine Dubé, Beril Kara, Hazal Cansu Acar, Barış İnan, Özden Aksu Sayman, Germain Lebel, Ray Bustinza, Hüseyin Küçükali, Umur Güven, Pierre Gosselin,

Heat waves are one of the most common direct impacts of anthropogenic climate change and excess mortality their most apparent impact. While Turkey has experienced an increase in heat wave episodes between 1971 and 2016, no epidemiological studies have examined their potential impacts on public health so far. In this ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2019, 16(22):]

Cited: 3 times

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Optimal anthropometric measures to predict incidence of coronary heart disease in adults in Turkey.

Günay Can, Altan Onat, Ugurcan Sayili, Mert I Hayiroglu, Evin Ademoglu, Eray Yurtseven,

<h4>Background</h4>We aimed to identify the most suited anthropometric measure for the prediction of risk for incident coronary heart disease (CHD) among the Turkish population.<h4>Methods</h4>We collected data on body mass index, waist circumference (WC), hip circumference, waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and a body shape index. We analysed these using ... Read more >>

Natl Med J India (The National medical journal of India)
[2019, 32(6):334-341]

Cited: 0 times

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Rising rural body-mass index is the main driver of the global obesity epidemic in adults.

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Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities<sup>1,2</sup>. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity<sup>3-6</sup>. Here we use ... Read more >>

Nature (Nature)
[2019, 569(7755):260-264]

Cited: 101 times

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Cardiovascular Risk Factors Associated With Venous Thromboembolism.

John Gregson, Stephen Kaptoge, Thomas Bolton, Lisa Pennells, Peter Willeit, Stephen Burgess, Steven Bell, Michael Sweeting, Eric B Rimm, Christopher Kabrhel, Bengt Zöller, Gerd Assmann, Vilmundur Gudnason, Aaron R Folsom, Volker Arndt, Astrid Fletcher, Paul E Norman, Børge G Nordestgaard, Akihiko Kitamura, Bakhtawar K Mahmoodi, Peter H Whincup, Matthew Knuiman, Veikko Salomaa, Christa Meisinger, Wolfgang Koenig, Maryam Kavousi, Henry Völzke, Jackie A Cooper, Toshiharu Ninomiya, Edoardo Casiglia, Beatriz Rodriguez, Yoav Ben-Shlomo, Jean-Pierre Després, Leon Simons, Elizabeth Barrett-Connor, Cecilia Björkelund, Marlene Notdurfter, Daan Kromhout, Jackie Price, Susan E Sutherland, Johan Sundström, Jussi Kauhanen, John Gallacher, Joline W J Beulens, Rachel Dankner, Cyrus Cooper, Simona Giampaoli, Jason F Deen, Agustín Gómez de la Cámara, Lewis H Kuller, Annika Rosengren, Peter J Svensson, Dorothea Nagel, Carlos J Crespo, Hermann Brenner, Juan R Albertorio-Diaz, Robert Atkins, Eric J Brunner, Martin Shipley, Inger Njølstad, Deborah A Lawlor, Yvonne T van der Schouw, Randi Marie Selmer, Maurizio Trevisan, W M Monique Verschuren, Philip Greenland, Sylvia Wassertheil-Smoller, Gordon D O Lowe, Angela M Wood, Adam S Butterworth, Simon G Thompson, John Danesh, Emanuele Di Angelantonio, Tom Meade, ,

<h4>Importance</h4>It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE).<h4>Objective</h4>To estimate the associations of major cardiovascular risk factors with VTE, ie, deep vein thrombosis and pulmonary embolism.<h4>Design, setting, and participants</h4>This study included individual participant data mostly from essentially population-based cohort studies from the Emerging ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2019, 4(2):163-173]

Cited: 39 times

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