Full Text Journal Articles by
Author Guillaume Aubry

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Single-molecule FISH in C. elegans embryos reveals early embryonic expression dynamics of par-2 , lgl-1 and chin-1 and possible differences between hyper-diverged strains.

Samiksha Kaul, Han Ting Chou, Seleipiri Charles, Guillaume Aubry, Hang Lu, Annalise B Paaby,

Wild <i>C. elegans</i> strains harbor natural variation in developmental pathways, but investigating these differences requires precise and well-powered phenotyping methods. Here we employ a microfluidics platform for single-molecule FISH to simultaneously visualize the transcripts of three genes in embryos of two distinct strains. We capture transcripts at high resolution by ... Read more >>

MicroPubl Biol (microPublication biology)
[2022, 2022:]

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Automated and Dynamic Control of Chemical Content in Droplets for Scalable Screens of Small Animals.

Guillaume Aubry, Marija Milisavljevic, Hang Lu,

Screening functional phenotypes in small animals is important for genetics and drug discovery. Multiphase microfluidics has great potential for enhancing throughput but has been hampered by inefficient animal encapsulation and limited control over the animal's environment in droplets. Here, a highly efficient single-animal encapsulation unit, a liquid exchanger system for ... Read more >>

Small (Small (Weinheim an der Bergstrasse, Germany))
[2022, 18(17):e2200319]

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