Full Text Journal Articles by
Author Guilherme Macedo

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COVID-19 and celiac disease - concerns to be addressed.

Isabel Garrido, Armando Peixoto, Guilherme Macedo,

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2021, 33(11):1460-1461]

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Duodenal-type follicular lymphoma -a silent tumor.

Isabel Garrido, João Santos-Antunes, Hélder Cardoso, Guilherme Macedo,

A 79-year-old male, with a past medical history of hypertension, dyslipidemia and type 2 diabetes, underwent routine esophagogastroduodenoscopy and colonoscopy. The patient was asymptomatic, with unremarkable blood tests. Upper gastrointestinal endoscopy showed multiple whitish nodular lesions in the first part of the duodenum. ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, :]

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Letter: universal screening for hepatitis C in pregnant women, children and adolescents.

Isabel Garrido, Guilherme Macedo,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(7):977-978]

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Upper Gastrointestinal Bleeding in a Patient with Liver Cirrhosis: Gastroesophageal Varices Are not Always to Blame.

Emanuel Dias, Fernando Azevedo, Ana Afonso, Guilherme Macedo,

A 45-year-old male with active alcoholism and liver cirrhosis was brought to emergency room with hypovolemic shock in context of diarrhea and melena. He presented with hemodynamic instability, hyperlactatemia and anemia. Aggressive supportive therapy with vasopressor support, packed red blood cell transfusion and intra-venous proton pump inhibitor was started. Upper ... Read more >>

J Gastrointestin Liver Dis (Journal of gastrointestinal and liver diseases : JGLD)
[2021, 30(3):323]

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Artificial intelligence for automatic diagnosis of biliary strictures malignancy status in single-operator cholangioscopy: a pilot study.

Miguel Mascarenhas Saraiva, Tiago Ribeiro, João P S Ferreira, Filipe Vilas Boas Silva, João Afonso, Ana Luísa Santos, Marco P L Parente, Renato N Jorge, Pedro Pereira, Guilherme Macedo,

<h4>Background and aims</h4>Diagnosis and characterization of biliary strictures is challenging. The introduction of digital single-operator cholangioscopy (DSOC) allowing direct visual inspection of the lesion and targeted biopsies significantly improved the diagnostic yield in patients with indeterminate biliary strictures. However, the diagnostic efficiency of DSOC remains suboptimal. Convolutional neural networks (CNNs) ... Read more >>

Gastrointest Endosc (Gastrointestinal endoscopy)
[2021, :]

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Artificial intelligence and capsule endoscopy: automatic detection of enteric protruding lesions using a convolutional neural network.

Miguel Mascarenhas Saraiva, João Afonso, Tiago Ribeiro, João Ferreira, Hélder Cardoso, Patricia Andrade, Raquel Gonçalves, Pedro Cardoso, Marco Parente, Renato Jorge, Guilherme Macedo,

<h4>Background and aims</h4>Capsule endoscopy (CE) revolutionized the study of the small intestine. Nevertheless, reviewing CE images is a time-consuming and prone to error. Artificial intelligence algorithms, particularly convolutional neural networks (CNN) are expected to overcome these drawbacks. Protruding lesions of the small intestine exhibit enormous morphological diversity in CE images. ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, :]

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A case of duodenal-type follicular lymphoma.

Joel Ferreira Silva, Rui Morais, Elsa Fonseca, Guilherme Macedo,

An 83 years-old female with history of silicosis was referred for upper endoscopy for duodenal wall thickness detected in thoracic computer tomography (CT). Upper endoscopy revealed multiple small (1 to 5mm) whitish polypoid lesions, involving a discrete portion of the descending part of the duodenum with 3cm of extension. ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, :]

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Very low rate of residual neoplasia after non-curative endoscopic submucosal dissection: a western single-center experience.

João Santos-Antunes, Margarida Marques, Fátima Carneiro, Guilherme Macedo,

<h4>Background</h4>Short and long outcomes of endoscopic submucosal dissection (ESD) are now well described. However, the outcome of non-curative ESDs is scarcely reported.<h4>Objective</h4>To describe our experience with non-curative ESDs, assessing the presence of residual lesion in the endoscopic follow-up or surgery.<h4>Methods</h4>Data of all the patients submitted to ESD between January 2015 ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2021, 33(9):1161-1166]

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Deep learning and capsule endoscopy: automatic identification and differentiation of small bowel lesions with distinct haemorrhagic potential using a convolutional neural network.

Miguel José Mascarenhas Saraiva, João Afonso, Tiago Ribeiro, João Ferreira, Helder Cardoso, Ana Patricia Andrade, Marco Parente, Renato Natal, Miguel Mascarenhas Saraiva, Guilherme Macedo,

<h4>Objective</h4>Capsule endoscopy (CE) is pivotal for evaluation of small bowel disease. Obscure gastrointestinal bleeding most often originates from the small bowel. CE frequently identifies a wide range of lesions with different bleeding potentials in these patients. However, reading CE examinations is a time-consuming task. Convolutional neural networks (CNNs) are highly ... Read more >>

BMJ Open Gastroenterol (BMJ open gastroenterology)
[2021, 8(1):]

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Kaposi´s sarcoma with atypical gastrointestinal involvement.

Isabel Garrido, João Pacheco, Rosa Coelho, Guilherme Macedo,

A 31-year-old male, who had tested HIV positive, presented with weight loss, asthenia and anorexia with 3 weeks of evolution. On physical exam, the patient had painless purple-coloured papules on the trunk and upper limbs. Laboratory studies revealed severe immunosuppression, with an absolute CD4 cell count of 114cell/uL and HIV1-RNA ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, :]

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The impact of undiagnosed primary biliary cholangitis.

Isabel Garrido, Rodrigo Liberal, Maria João Cardoso, Guilherme Macedo,

<h4>Background</h4>Primary biliary cholangitis (PBC) is a chronic autoimmune disease characterized by symptoms with a major impact on the quality of life. The aim of this study was to identify patients with undiagnosed PBC who are not under hepatology follow-up and to assess the clinical impact of lack of adequate treatment ... Read more >>

Eur J Gastroenterol Hepatol (European journal of gastroenterology & hepatology)
[2021, :]

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Gastroduodenal ischemia in a patient with severe SARS-CoV-2 infection.

Isabel Garrido, Armando Peixoto, Guilherme Macedo,

A 54-year-old male, with a past medical history of hypertension, dyslipidemia, obesity and diastolic heart failure, was admitted due to COVID-19 pneumonia. Respiratory failure gradually deteriorated and the patient was transferred to the Intensive Care Unit (ICU), where mechanical ventilation and venovenous extracorporeal membrane oxygenation (VV-ECMO) were started. On the ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, :]

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Transient splenic elastography predicts high-risk esophageal varices in patients with non-cirrhotic portal hypertension.

Joel Ferreira-Silva, Rui Gaspar, Rodrigo Liberal, Hélder Cardoso, Guilherme Macedo,

<h4>Background and aims</h4>Non-cirrhotic portal hypertension (NCPH) comprise a group of diseases that cause portal hypertension without cirrhosis, leading to a high risk of hemorrhage from esophageal varices. There are no non-invasive predictors of high-risk varices (HRV) described in the literature for NCPH. This study aimed to evaluate whether transient splenic ... Read more >>

Scand J Gastroenterol (Scandinavian journal of gastroenterology)
[2021, :1-5]

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The ACE (Albumin, CRP, and Endoscopy) Index in Acute Colitis: Simplify to a Better Prognostic Prediction.

Ana Luísa Santos, Susana Lopes, Armando Peixoto, Isabel Garrido, Renato Medas, Patrícia Andrade, Guilherme Macedo,

Inflamm Bowel Dis (Inflammatory bowel diseases)
[2021, :]

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A consensus integrated care pathway for patients with primary biliary cholangitis: a guideline-based approach to clinical care of patients.

Gideon M Hirschfield, Olivier Chazouillères, Helena Cortez-Pinto, Guilherme Macedo, Victor de Lédinghen, Femi Adekunle, Marco Carbone,

<h4>Introduction</h4>Primary biliary cholangitis (PBC) is an infrequent, immune-mediated cholestatic liver disease, which can lead to liver fibrosis, cirrhosis and complications of end-stage liver disease. The established goals of treatment of PBC are prevention of end-stage liver disease and amelioration of associated symptoms. The European Association for the Study of the ... Read more >>

Expert Rev Gastroenterol Hepatol (Expert review of gastroenterology & hepatology)
[2021, 15(8):929-939]

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An Unexpected Colonic Polyp: Cavernous Hemangioma.

Miguel Mascarenhas, Rui Morais, Regina Teixeira, Guilherme Macedo,

Cavernous hemangiomas of the colon are rare, benign vascular lesions, and the site most commonly affected is the rectosigmoid junction. Surgical treatment is recommended for large diffuse lesions but in the presence of pedunculated lesions, endoscopic resection should be preferred if possible. We report a case of a 65-year-old man ... Read more >>

Ann Coloproctol (Annals of coloproctology)
[2021, :]

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Extensive Abdominal Wall Hematoma After Paracentesis.

Renato Medas, Isabel Garrido, Rosa Coelho, Guilherme Macedo,

Am J Gastroenterol (The American journal of gastroenterology)
[2021, :]

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A case of severe diverticulosis in a patient with ulcerative colitis.

Emanuel Dias, João Santos-Antunes, Guilherme Macedo,

A 50-year-old female with ulcerative colitis (UC) (pancolitis) for 13 years was referred for a screening colonoscopy. At onset, she presented with severely active disease and required intravenous corticosteroids to induce remission. Since then, the disease has been in remission with oral mesalamine and azathioprine and she remains steroid-free, without ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, 113(7):550-551]

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Nodular Lymphoid Hyperplasia of the Rectum in a Patient With Primary Immunodeficiency.

João Santos-Antunes, Fátima Carneiro, Guilherme Macedo,

Am J Gastroenterol (The American journal of gastroenterology)
[2021, 116(7):1375]

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Endoscopic diagnosis of primary and recurrent mantle cell lymphomas.

Miguel Mascarenhas Saraiva, Tiago Filipe Ribeiro, Amadeu Corte Real Nunes, Guilherme Macedo,

A 64-year-old male presented to our center with epigastric pain, anorexia, fatigue, weight loss and anemia on a laboratory study. An abdominal ultrasound revealed thickening of the gastric walls. Upper endoscopy demonstrated a 40 mm ulcerated lesion at the incisura angularis. A biopsy of the lesion revealed a lymphocytic infiltrate ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, 113(7):552-553]

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Artificial intelligence and colon capsule endoscopy: automatic detection of blood in colon capsule endoscopy using a convolutional neural network.

Miguel Mascarenhas Saraiva, João P S Ferreira, Hélder Cardoso, João Afonso, Tiago Ribeiro, Patrícia Andrade, Marco P L Parente, Renato N Jorge, Guilherme Macedo,

Colon capsule endoscopy (CCE) is a minimally invasive alternative to conventional colonoscopy. Most studies on CCE focus on colorectal neoplasia detection. The development of automated tools may address some of the limitations of this diagnostic tool and widen its indications for different clinical settings. We developed an artificial intelligence model ... Read more >>

Endosc Int Open (Endoscopy international open)
[2021, 9(8):E1264-E1268]

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Unexpected diagnosis for nodular hepatic lesions.

Isabel Garrido, Rosa Coelho, Joanne Lopes, Guilherme Macedo,

Uveal melanoma is the most common primary ocular tumor and has a significant predilection for metastasis to the liver. Nevertheless, metastatic uveal melanoma usually occurs in the first years after the initial treatment and late recurrence is extremely rare. ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, :]

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Stent deployment within a transesophagostomy orifice to treat a postgastrectomy leak.

Eduardo Rodrigues-Pinto, Joel Ferreira-Silva, Pedro Pereira, Guilherme Macedo,

Video 1Endoscopic treatment of a postgastrectomy leak with self-expandable metal stents and endoscopic internal drainage. ... Read more >>

VideoGIE (VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy)
[2021, 6(10):454-456]

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Gastric caustic injury after organophosphate poisoning.

Miguel Mascarenhas Saraiva, Tiago Filipe Ribeiro, Filipe Vilas Boas, Guilherme Macedo,

An 83-year-old male was brought to the Emergency Room after ingesting an unknown dose of dimethoate, an organophosphate pesticide. He had been previously diagnosed with depression but there were no previous suicide attempts. The admission Glasgow Coma Scale score was 3 and he had miotic pupils and copious oropharyngeal secretions. ... Read more >>

Rev Esp Enferm Dig (Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva)
[2021, 113(7):551]

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Acute severe autoimmune hepatitis - timing for steroids and role of other immunosuppressive agents.

Rodrigo Liberal, Guilherme Macedo,

J Hepatol (Journal of hepatology)
[2021, 75(2):494-495]

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