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Author Guanjun Chen

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Characterization of the (Engineered) Branching Sucrase GtfZ-CD2 from Apilactobacillus kunkeei for Efficient Glucosylation of Benzenediol Compounds.

Xiangfeng Meng, Xiaodan Li, Tjaard Pijning, Xiaofei Wang, Sander S van Leeuwen, Lubbert Dijkhuizen, Guanjun Chen, Weifeng Liu,

Branching sucrases, a subfamily of Glycoside Hydrolase family (GH70), display transglycosidase activity using sucrose as donor substrate to catalyze glucosylation reaction in the presence of suitable acceptor substrates. In this study, the (α1→3) branching sucrase GtfZ-CD2 from <i>Apilactobacillus kunkeei</i> DSM 12361 was demonstrated to glucosylate benzenediol compounds (i.e., catechol, resorcinol, ... Read more >>

Appl Environ Microbiol (Applied and environmental microbiology)
[2022, 88(16):e0103122]

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Fluorescent Labeling of Polymannuronic Acid and Its Distribution in Mice by Tail Vein Injection.

Shuliang Song, Qiang Wei, Ke Wang, Qiong Yang, Yu Wang, Aiguo Ji, Guanjun Chen,

Polymannuronic acid (PM) possesses more pharmacological activities than sodium alginate, but there have been few studies on its absorption mechanism, tissue distribution, and pharmacokinetics. Studies of pharmacokinetics and tissue distribution are necessary to elucidate the pharmacological effects of PM. Thus, we used fluorescein isothiocyanate (FITC) to produce fluorescently labeled PM ... Read more >>

Mar Drugs (Marine drugs)
[2022, 20(5):289]

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