Full Text Journal Articles by
Author Grace Lim

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Perinatal depression.

Grace Lim,

<h4>Purpose of review</h4>Perinatal depression is a common and debilitating complication of pregnancy and childbirth. Recent studies have elucidated relationships between acute birth events on depression risk, and novel treatments for postpartum depression have been discovered and approved. This article reviews current understandings about birth events on depression, new screening standards, ... Read more >>

Curr Opin Anaesthesiol (Current opinion in anaesthesiology)
[2021, 34(3):233-237]

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Society for Obstetric Anesthesia and Perinatology: Consensus Statement and Recommendations for Enhanced Recovery After Cesarean.

Laurent Bollag, Grace Lim, Pervez Sultan, Ashraf S Habib, Ruth Landau, Mark Zakowski, Mohamed Tiouririne, Sumita Bhambhani, Brendan Carvalho,

The purpose of this article is to provide a summary of the Enhanced Recovery After Cesarean delivery (ERAC) protocol written by a Society for Obstetric Anesthesia and Perinatology (SOAP) committee and approved by the SOAP Board of Directors in May 2019. The goal of the consensus statement is to provide ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, 132(5):1362-1377]

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Neutrophil-to-Lymphocyte Ratio Predicts Development of Immune-Related Adverse Events and Outcomes from Immune Checkpoint Blockade: A Case-Control Study.

Pei Yi Lee, Kellynn Qi Xuan Oen, Grace Rui Si Lim, Juanda Leo Hartono, Mark Muthiah, Daniel Q Huang, Felicia Su Wei Teo, Andrew Yunkai Li, Anselm Mak, Nisha Suyien Chandran, Chris Lixian Tan, Peiling Yang, E Shyong Tai, Kay Wei Ping Ng, Joy Vijayan, Yee Cheun Chan, Li Ling Tan, Martin Beng-Huat Lee, Horng Ruey Chua, Wei Zhen Hong, Eng Soo Yap, Dawn K Lim, Yew Sen Yuen, Yiong Huak Chan, Folefac Aminkeng, Alvin Seng Cheong Wong, Yiqing Huang, Sen Hee Tay,

The utility of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) utility in predicting immune-related adverse events (irAEs) and survival have not been well studied in the context of treatment with immune checkpoint inhibitors (ICIs). We performed a case-control study of cancer patients who received at least one dose of ICI ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(6):]

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Prevalence and risk factors for falls in patients with spondyloarthritis: A systematic review.

Grace Rui Si Lim, Caitlin Hsuen Ng, Yu Heng Kwan, Warren Fong,

<h4>Objective</h4>Patients with spondyloarthritis (SpA) may have a greater risk of falling due to poor postural balance and decreased mobility. To our best knowledge, there are no published reviews that study falls in patients with SpA. Therefore, we aim to systematically review the literature and identify the prevalence and risk factors ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2021, 24(5):623-632]

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Mechanistic insights into spinal neurones involved in neuraxial opioid-induced pruritus.

Eileen Nguyen, Grace Lim, Sarah E Ross,

Br J Anaesth (British journal of anaesthesia)
[2021, 126(5):e179-e181]

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ECT for a pregnant patient with bipolar disorder in the COVID-19 Era: A clinical conundrum.

Jessica M Gannon, Priya Gopalan, LalithKumar K Solai, Grace Lim, Jaclyn M Phillips, Stacy Beck, Eydie Moses-Kolko, Donald Miller, K N Roy Chengappa,

Bipolar Disord (Bipolar disorders)
[2021, :]

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Morphine acts on spinal dynorphin neurons to cause itch through disinhibition.

Eileen Nguyen, Grace Lim, Huiping Ding, Junichi Hachisuka, Mei-Chuan Ko, Sarah E Ross,

Morphine-induced itch is a very common and debilitating side effect that occurs in laboring women who receive epidural analgesia and in patients who receive spinal morphine for relief of perioperative pain. Although antihistamines are still widely prescribed for the treatment of morphine-induced itch, their use is controversial because the cellular ... Read more >>

Sci Transl Med (Science translational medicine)
[2021, 13(579):]

Cited: 1 time

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Case Report of Remifentanil Labor Analgesia for a Pregnant Patient With Congenital Methemoglobinemia Type 1.

Wu Yin, Francesca Jung, Douglas Adams, Gerhardt Konig, Ryan C Romeo, Grace Lim,

Congenital methemoglobinemia is a rare disease characterized by cyanosis and a left shifting of the oxyhemoglobin dissociation curve. The disease necessitates avoidance of certain medications commonly used in obstetrics, making labor analgesia and anesthesia challenging. We present a case report of peripartum anesthetic management of a pregnant patient with congenital ... Read more >>

A A Pract (A&A practice)
[2021, 15(1):e01373]

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The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model.

Samuel L McCaffrey, Grace Lim, Martyn Bullock, Ainsley O Kasparian, Roderick Clifton-Bligh, William B Campbell, Alexander Widiapradja, Scott P Levick,

Histamine is a basic amine stored in mast cells, with its release capable of activating one of four histamine receptors. The histamine 3 receptor (H<sub>3</sub>R) is known to be cardioprotective during acute ischemia by acting to limit norepinephrine release. However, a recent study reported that myofibroblasts isolated from the infarct ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(24):]

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Validation of the clinical utility of 4 guidelines in the initial triage of mucinous cystic lesions of the pancreas based on cross-sectional imaging: Experience with 188 surgically-treated patients.

Rachel H S Park, Grace R S Lim, Jania J Y Wu, Ye-Xin Koh, Jin-Yao Teo, Peng-Chung Cheow, Chung-Yip Chan, London L P J Ooi, Alexander Y F Chung, Brian K P Goh,

<h4>Introduction</h4>Over the years, several guidelines have been introduced to guide management of mucinous pancreatic cystic neoplasms (mPCN). In this study, we aimed to evaluate and compare the clinically utility of the Sendai-06, Fukuoka-12, Fukuoka-17 and European-18 guidelines in predicting malignancy of mPCN.<h4>Methods</h4>One hundred and eighty-eight patients with mucinous cystic neoplasms ... Read more >>

Eur J Surg Oncol (European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology)
[2020, 46(11):2114-2121]

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Quality of English-language videos on YouTube as a source of information on systemic lupus erythematosus.

Caitlin Hsuen Ng, Grace Rui Si Lim, Warren Fong,

<h4>Background</h4>Many patients turn to online platforms to obtain healthcare information, but the quality and accuracy of the information is largely unknown. The objective of this study was to evaluate the reliability and quality of the most viewed English-language YouTube videos on systemic lupus erythematosus (SLE).<h4>Methods</h4>YouTube was searched using keywords "systemic ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2020, 23(12):1636-1644]

Cited: 1 time

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Obstetric pain correlates with postpartum depression symptoms: a pilot prospective observational study.

Grace Lim, Kelsea R LaSorda, Lia M Farrell, Ann M McCarthy, Francesca Facco, Ajay D Wasan,

<h4>Background</h4>Data linking labor pain and postpartum depression are emerging. Robust, prospective evaluations of this relationship while factoring other important variables are lacking. We assessed perinatal pain and other factors predicting postpartum depression (PPD) symptoms.<h4>Methods</h4>Third trimester women, stratified by a priori plan to receive or avoid labor epidural analgesia, were longitudinally ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2020, 20(1):240]

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Effect of a Patient Education Strategy on Resident Self-Efficacy and Maternal Outcomes (EDUCATE Study)

Michelle Yanik, Andrea Pollack, Lia Farrell, David Metro, Tetsuro Sakai, Grace Lim,

<h4>Background: </h4> – Patient education improves treatment plan compliance and outcomes. For anesthesiology residents, patient communication is highlighted on the obstetric subspecialty rotation. However, the clinical effectiveness of patient education on patient-controlled epidural analgesia (PCEA) dose requirements is unknown. We hypothesized that patients receiving care by residents who are formally ... Read more >>

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To pee or not to pee: severe discomfort in a young air traveller.

Grace Hui Chin Lim, Bryan Chang Wei Lim, Gerard Thomas Flaherty,

J Travel Med (Journal of travel medicine)
[2020, 27(2):]

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Labor Pain, Analgesia, and Postpartum Depression: Are We Asking the Right Questions?

Grace Lim, Michele D Levine, Edward J Mascha, Ajay D Wasan,

Anesth Analg (Anesthesia and analgesia)
[2020, 130(3):610-614]

Cited: 1 time

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Resource utilization across the continuum of HIV care: An emergency department-based cohort study.

Abia Abia, Richard E Rothman, Amir M Mohareb, Grace Li Hsien Lim, Anuj V Patel, Benjamin Bigelow, Eili Y Klein, Gai Cole, Kelly A Gebo, Richard D Moore, Yu-Hsiang Hsieh,

<h4>Background</h4>The objective of this study was to determine the healthcare resource utilization for people living with HIV (PLWH) presenting to the emergency department (ED) across the HIV Care Continuum.<h4>Methods</h4>This prospective study enrolled PLWH presenting to an urban ED between June 2016 and March 2017. Subjects were categorized as being linked ... Read more >>

Am J Emerg Med (The American journal of emergency medicine)
[2021, 43:164-169]

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Potassium channel dysfunction in human neuronal models of Angelman syndrome.

Alfred Xuyang Sun, Qiang Yuan, Masahiro Fukuda, Weonjin Yu, Haidun Yan, Grace Gui Yin Lim, Mui Hoon Nai, Giuseppe Alessandro D'Agostino, Hoang-Dai Tran, Yoko Itahana, Danlei Wang, Hidayat Lokman, Koji Itahana, Stephanie Wai Lin Lim, Jiong Tang, Ya Yin Chang, Menglan Zhang, Stuart A Cook, Owen J L Rackham, Chwee Teck Lim, Eng King Tan, Huck Hui Ng, Kah Leong Lim, Yong-Hui Jiang, Hyunsoo Shawn Je,

Disruptions in the ubiquitin protein ligase E3A (<i>UBE3A</i>) gene cause Angelman syndrome (AS). Whereas AS model mice have associated synaptic dysfunction and altered plasticity with abnormal behavior, whether similar or other mechanisms contribute to network hyperactivity and epilepsy susceptibility in AS patients remains unclear. Using human neurons and brain organoids, ... Read more >>

Science (Science (New York, N.Y.))
[2019, 366(6472):1486-1492]

Cited: 13 times

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ETS Factor ETV5 Activates the Mutant Telomerase Reverse Transcriptase Promoter in Thyroid Cancer.

Martyn Bullock, Grace Lim, Ying Zhu, Helena Åberg, Sergey Kurdyukov, Roderick Clifton-Bligh,

<b><i>Background:</i></b> Co-occurrence of <i>TERT</i> (telomerase reverse transcriptase) promoter (TERTp) mutations with <i>BRAF</i>/<i>RAS</i> mutations is associated with significantly more aggressive thyroid cancer. TERTp mutations are hypothesized to generate <i>de novo</i> binding sites for ETS transcription factors, which are themselves activated by BRAF/RAS-stimulated MEK-ERK activity. To date, a detailed study of this ... Read more >>

Thyroid (Thyroid : official journal of the American Thyroid Association)
[2019, 29(11):1623-1633]

Cited: 4 times

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A review of peripheral nerve blocks for cesarean delivery analgesia.

Kelsey D Mitchell, C Tyler Smith, Courtney Mechling, Charles B Wessel, Steven Orebaugh, Grace Lim,

Peripheral nerve blocks have a unique role in postcesarean delivery multimodal analgesia regimens. In this review article, options for peripheral nerve blocks for cesarean delivery analgesia will be reviewed, specifically paravertebral, transversus abdominis plane, quadratus lumborum, iliohypogastric and ilioinguinal, erector spinae, and continuous wound infiltration blocks. Anatomy, existing literature evidence, ... Read more >>

Reg Anesth Pain Med (Regional anesthesia and pain medicine)
[2019, :]

Cited: 4 times

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Auricular percutaneous nerve field stimulator device as alternative therapy for Cesarean delivery analgesia: proof of concept.

Grace Lim, Kelsea R LaSorda, Amy L Monroe, Jacques E Chelly,

Can J Anaesth (Canadian journal of anaesthesia = Journal canadien d'anesthesie)
[2019, 66(12):1522-1523]

Cited: 0 times

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Magnetic resonance imaging for placenta accreta: hope for the future.

Grace Lim, Marc Lim, Jeanne M Horowitz,

Am J Obstet Gynecol (American journal of obstetrics and gynecology)
[2019, 221(5):536-537]

Cited: 0 times

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Ultrasound-assisted epidural labor analgesia for landmark identification in morbidly obese pregnant women: A preliminary investigation.

Thomas J Vernon, Tracey M Vogel, Patricia L Dalby, Gordon Mandell, Grace Lim,

J Clin Anesth (Journal of clinical anesthesia)
[2020, 59:53-54]

Cited: 2 times

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Maternal Mirror Syndrome Masquerading as Congestive Heart Failure: A Case Report.

Wen Xu, C Tyler Smith, Anna Binstock, Grace Lim,

Mirror syndrome is a rare pregnancy complication, life-threatening to mother and fetus. Increasing survival rates of congenital heart disease into reproductive age mean that complications like Mirror syndrome in this population may be more challenging to diagnose, given overlapping signs of edema in cases of heart failure exacerbation. We report ... Read more >>

A A Pract (A&A practice)
[2019, 12(11):447-451]

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Global variation in anastomosis and end colostomy formation following left-sided colorectal resection.

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<h4>Background</h4>End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.<h4>Methods</h4>This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, ... Read more >>

BJS Open (BJS open)
[2019, 3(3):403-414]

Cited: 1 time

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Genetic associations of perinatal pain and depression.

Lora McClain, Lia Farrell, Kelsea LaSorda, Lisa A Pan, David Peters, Grace Lim,

Mol Pain (Molecular pain)
[2019, 15:1744806919882139]

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