Full Text Journal Articles by
Author Gordon Parker

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Melancholia: dimensional or categorical?

Diego J Martino, Marina P Valerio, Gordon Parker,

J Affect Disord (Journal of affective disorders)
[2020, 278:395-396]

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The bipolar disorders: A case for their categorically distinct status based on symptom profiles.

Gordon Parker, Michael J Spoelma, Gabriela Tavella, Martin Alda, Tomas Hajek, David L Dunner, Claire O'Donovan, Janusz K Rybakowski, Joseph F Goldberg, Adam Bayes, Verinder Sharma, Philip Boyce, Vijaya Manicavasagar,

BACKGROUND:It is unclear whether the bipolar disorders (i.e. BP-I/BP-II) differ dimensionally or categorically. This study sought to clarify this issue. METHODS:We recruited 165 patients, of which 69 and 96 had clinician-assigned diagnoses of BP-I and BP-II respectively. Their psychiatrists completed a data sheet seeking information on clinical variables about each ... Read more >>

J Affect Disord (Journal of affective disorders)
[2020, 277:225-231]

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Sydney Melancholia Prototype Index (SMPI): translation and cross-cultural adaptation to Brazilian Portuguese.

Mateus Frizzo Messinger, Marco Antonio Caldieraro, Bruno Paz Mosqueiro, Felipe Bauer Pinto da Costa, Gabriela Maria Pereira Possebon, Pedro Victor de Lima Nascimento Santos, Gordon Parker, Marcelo P Fleck,

INTRODUCTION:Depression is possibly not a single syndrome but rather comprises several subtypes. DSM-5 proposes a melancholia specifier with phenotypic characteristics that could be associated with clinical progression, biological markers or therapeutic response. The Sydney Melancholia Prototype Index (SMPI) is a prototypic scale aimed to improve the diagnosis of melancholia. So ... Read more >>

Trends Psychiatry Psychother (Trends in psychiatry and psychotherapy)
[2020, 42(3):247-255]

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Psychotherapy or medication for depression? Using individual symptom meta-analyses to derive a Symptom-Oriented Therapy (SOrT) metric for a personalised psychiatry.

Nils Kappelmann, Martin Rein, Julia Fietz, Helen S Mayberg, W Edward Craighead, Boadie W Dunlop, Charles B Nemeroff, Martin Keller, Daniel N Klein, Bruce A Arnow, Nusrat Husain, Robin B Jarrett, Jeffrey R Vittengl, Marco Menchetti, Gordon Parker, Jacques P Barber, Andre G Bastos, Jack Dekker, Jaap Peen, Martin E Keck, Johannes Kopf-Beck,

BACKGROUND:Antidepressant medication (ADM) and psychotherapy are effective treatments for major depressive disorder (MDD). It is unclear, however, if treatments differ in their effectiveness at the symptom level and whether symptom information can be utilised to inform treatment allocation. The present study synthesises comparative effectiveness information from randomised controlled trials (RCTs) ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):170]

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Distinguishing burnout from depression: An exploratory qualitative study.

Gabriela Tavella, Gordon Parker,

Whether depression and burnout are synonymous or not has been a longstanding debate. Many studies have examined for similarities and differences, but findings have overall been inconclusive, with most studies being quantitative in design. We therefore undertook a qualitative study in which participants who self-identified as having experienced both burnout ... Read more >>

Psychiatry Res (Psychiatry research)
[2020, 291:113212]

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The well-being of medical students: A biopsychosocial approach.

Ute Vollmer-Conna, Jessica E Beilharz, Erin Cvejic, Claire L Macnamara, Michelle Doherty, Zachary Steel, Dusan Hadzi-Pavlovic, Samuel B Harvey, Gordon Parker,

OBJECTIVE:Mental health problems among medical students have been widely reported, but the predisposing and perpetuating factors and biological concomitants are poorly understood. Adopting a biopsychosocial approach, we studied well-being in a group of Australian medical students, focusing on sleep, autonomic and immune mechanisms, as well as mental, social and physical ... Read more >>

Aust N Z J Psychiatry (The Australian and New Zealand journal of psychiatry)
[2020, 54(10):997-1006]

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Do Hamilton depression scale items have the capacity to differentiate melancholic and non-melancholic depressive sub-types?

Gordon Parker, Dusan Hadzi-Pavlovic,

BACKGROUND:While there have been several Hamilton depression sub-scales named as to indicate that they have the capacity to differentiate melancholic depression, all but one actually measure depression severity. As a valid Hamilton-derived melancholia scale would have high utility in evaluating the comparative effectiveness of differing treatments for melancholia we designed ... Read more >>

J Affect Disord (Journal of affective disorders)
[2020, 274:1022-1027]

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Placebo response rates in trials of antidepressant drugs in adults with clinical depression: Increasing, decreasing, constant or all of the above?

Gordon Parker, Tahlia Ricciardi, Dusan Hadzi-Pavlovic,

OBJECTIVE:A seminal study quantified an increase in placebo (and drug) response rates in antidepressant trials during the eighties, with subsequent key systematic reviews reporting placebo response rates as either having continued to increase or stabilize in trial subjects with major depression. We therefore undertook an additional study examining a more ... Read more >>

J Affect Disord (Journal of affective disorders)
[2020, 271:139-144]

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Cognitive side-effects of electroconvulsive therapy: what are they, how to monitor them and what to tell patients.

Richard J Porter, Bernhard T Baune, Grace Morris, Amber Hamilton, Darryl Bassett, Philip Boyce, Malcolm J Hopwood, Roger Mulder, Gordon Parker, Ajeet B Singh, Tim Outhred, Pritha Das, Gin S Malhi,

BACKGROUND:Electroconvulsive therapy (ECT) is recommended in treatment guidelines as an efficacious therapy for treatment-resistant depression. However, it has been associated with loss of autobiographical memory and short-term reduction in new learning. AIMS:To provide clinically useful guidelines to aid clinicians in informing patients regarding the cognitive side-effects of ECT and in ... Read more >>

(BJPsych open)
[2020, 6(3):e40]

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A Review of Antidepressant-Associated Hypomania in Those Diagnosed with Unipolar Depression-Risk Factors, Conceptual Models, and Management.

Nav Gill, Adam Bayes, Gordon Parker,

PURPOSE OF REVIEW:The nosology and management of antidepressant-associated hypomania (AAH) in the treatment of unipolar depression requires clarification. We sought to review recent studies examining AAH, focusing on risk factors, differing explanatory models, and management strategies. RECENT FINDINGS:AAH occurs more frequently in those of female gender, younger age, and with ... Read more >>

Curr Psychiatry Rep (Current psychiatry reports)
[2020, 22(4):20]

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Burnout: Re-examining its key constructs.

Gabriela Tavella, Dusan Hadzi-Pavlovic, Gordon Parker,

There is widespread debate as to how to accurately define and measure burnout. The present study sought to address these issues by inviting participants who self-identified as experiencing burnout to complete a questionnaire covering a large item set of putative burnout features. Bifactor modelling identified a 'general' factor with items ... Read more >>

Psychiatry Res (Psychiatry research)
[2020, 287:112917]

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Pseudo-melancholia.

Gordon Parker,

OBJECTIVE:An incorrect false positive diagnosis of melancholia can lead to inappropriate treatment and illness prolongation. This paper therefore seeks to introduce the concept of 'pseudo-melancholia' to capture such instances and provide clinical examples of contributing at-risk scenarios. METHODS:The author draws on clinical experience to provide exemplars of circumstances most risking ... Read more >>

Australas Psychiatry (Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists)
[2020, 28(3):339-341]

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Acute coronary syndrome-associated depression: Getting to the heart of the data.

Gordon Parker, Darryl Bassett, Philip Boyce, Bill Lyndon, Roger Mulder, Richard Porter, Ajeet Singh, Erica Bell, Amber Hamilton, Grace Morris, Michael J Spoelma, Gin S Malhi,

OBJECTIVES:We sought to identify and consider methodological issues that may have limited or confounded investigations into links between depression and acute coronary syndrome (ACS) events. METHODS:We reviewed salient research studies to identify such issues. RESULTS:Against previous conclusions, we found that lifetime depression is unlikely to have any primary ACS impact, ... Read more >>

J Affect Disord (Journal of affective disorders)
[2020, 269:70-77]

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The structure of mania: An overview of factorial analysis studies.

Diego J Martino, Marina P Valerio, Gordon Parker,

BACKGROUND.:Operational definitions of mania are based on expert consensus rather than empirical data. The aim of this study is to identify the key domains of mania, as well as the relevance of the different signs and symptoms of this clinical construct. METHODS.:A review of latent factor models studies in manic ... Read more >>

Eur. Psychiatry (European psychiatry : the journal of the Association of European Psychiatrists)
[2020, 63(1):e10]

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A Qualitative Reexamination of the Key Features of Burnout.

Gabriela Tavella, Gordon Parker,

Burnout is generally defined as a triad of emotional exhaustion, lack of empathy, and reduced professional accomplishment constructs. We sought to determine in an exploratory, qualitative study whether these three constructs adequately represent burnout. Participants who self-identified as experiencing burnout completed a questionnaire that asked about their experiences of the ... Read more >>

J. Nerv. Ment. Dis. (The Journal of nervous and mental disease)
[2020, 208(6):452-458]

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Non-consensual recommendations for managing bipolar II disorder.

Gordon Parker,

OBJECTIVE:The objective of this study is to report on the degree of consensus in experts' recommendations for managing bipolar II disorder. METHODS:Eighteen international clinician researchers with expertise in managing bipolar disorders were provided with 14 questions addressing nuances in managing those with a bipolar II disorder. RESULTS:To all questions, the ... Read more >>

Australas Psychiatry (Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists)
[2020, 28(3):335-338]

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Do Changes in Employment Status Induce or "Harvest" Suicides?

Gordon Parker,

In a seminal Swedish study, Gemmill and colleagues pursued whether suicides after economic contractions might reflect an "induction" process whereby economic change induces suicide in those otherwise unlikely to engage in self-destructive behavior, or a "displacement" process whereby economic contractions effectively bring forward suicides that would have occurred eventually, and ... Read more >>

J. Nerv. Ment. Dis. (The Journal of nervous and mental disease)
[2019, 207(12):1039-1044]

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Trying to describe mixed anxiety and depression: Have we lost our way?

Roger Mulder, Darryl Bassett, Grace Morris, Amber Hamilton, Bernhard T Baune, Philip Boyce, Malcolm Hopwood, Gordon Parker, Richard Porter, Ajeet B Singh, Pritha Das, Tim Outhred, Gin S Malhi,

Depress Anxiety (Depression and anxiety)
[2019, 36(12):1122-1124]

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Temporal effects of bitemporal electroconvulsive therapy.

Gordon Parker, Colleen Loo,

Aust N Z J Psychiatry (The Australian and New Zealand journal of psychiatry)
[2020, 54(4):433-434]

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Differential Diagnosis of Bipolar II Disorder and Borderline Personality Disorder.

Adam Bayes, Gordon Parker, Joel Paris,

PURPOSE OF REVIEW:Differentiating bipolar (BP) disorders (in particular BP II) from borderline personality disorder (BPD) is a common diagnostic dilemma. We sought to critically examine recent studies that considered clinical differences between BP II and BPD, which might advance their delineation. RECENT FINDINGS:Recent studies focused on differentiating biological parameters-genetics, epigenetics, ... Read more >>

Curr Psychiatry Rep (Current psychiatry reports)
[2019, 21(12):125]

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Switching antidepressants in the treatment of major depression: When, how and what to switch to?

Philip Boyce, Malcolm Hopwood, Grace Morris, Amber Hamilton, Darryl Bassett, Bernhard T Baune, Roger Mulder, Richard Porter, Gordon Parker, Ajeet B Singh, Tim Outhred, Pritha Das, Gin S Malhi,

BACKGROUND:Switching antidepressant medications is recommended when an initial antidepressant is not effective, when it is unable to be tolerated or when there are significant drug interactions. The aim of this paper is to review the evidence regarding when to switch antidepressants and the optimal approach to switching. METHODS:Clinical and academic ... Read more >>

J Affect Disord (Journal of affective disorders)
[2020, 261:160-163]

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Melancholia: An Attempt at Definition Based on a Review of Empirical Data.

Diego J Martino, Alejandro G Szmulewicz, Marina P Valerio, Gordon Parker,

We sought to identify clinical features that best discriminate melancholia from nonmelancholic depressive conditions. An extensive review of studies using latent factor models that identified a melancholic depression dimension/factor was undertaken. Clinical variables extracted from these studies were analyzed in terms of their contribution to a diagnosis of melancholia and ... Read more >>

J. Nerv. Ment. Dis. (The Journal of nervous and mental disease)
[2019, 207(9):792-798]

Cited: 1 time

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Cognitive and Behavioral Differentiation of Those With Borderline Personality Disorder and Bipolar Disorder.

Adam J Bayes, Gordon B Parker,

The current study sought to identify features offering differentiation of borderline personality disorder (BPD) from bipolar disorder (BP). Participants were clinically assessed and assigned diagnoses based on the Diagnostic and Statistical Manual of Mental Disorders criteria. A 113-item self-report questionnaire was completed, comprising cognitive and behavioral constructs weighted to a ... Read more >>

J. Nerv. Ment. Dis. (The Journal of nervous and mental disease)
[2019, 207(8):620-625]

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Australian psychiatrists on the world stage.

Gordon Parker,

OBJECTIVE:To nominate Australian psychiatrists no longer living who made a distinct international contribution and impact. METHOD:Personal choices were made in nominating five psychiatrists and with supportive arguments provided in reviewing their contributions. RESULTS:The five nominated psychiatrists were John Cade, Aubrey Lewis, Leslie Kiloh, Bernard Carroll and Issy Pilowsky. CONCLUSION:Background information ... Read more >>

Aust N Z J Psychiatry (The Australian and New Zealand journal of psychiatry)
[2020, 54(1):15-19]

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How Well Does the DSM-5 Capture Schizoaffective Disorder?

Gordon Parker,

Schizoaffective disorder has long been recognized and quite variably defined. It has been variably positioned as a discrete entity, a variant of either schizophrenia or of a mood disorder, as simply reflecting the co-occurrence of schizophrenia and a mood disorder, and effectively reflecting a diagnosis along a continuum linking schizophrenia ... Read more >>

Can J Psychiatry (Canadian journal of psychiatry. Revue canadienne de psychiatrie)
[2019, 64(9):607-610]

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