Full Text Journal Articles by
Author Gopal R Gopinath

Advertisement

Find full text journal articles






The Secretion of Toxins and Other Exoproteins of Cronobacter: Role in Virulence, Adaption, and Persistence.

Hyein Jang, Gopal R Gopinath, Athmanya Eshwar, Shabarinath Srikumar, Scott Nguyen, Jayanthi Gangiredla, Isha R Patel, Samantha B Finkelstein, Flavia Negrete, JungHa Woo, YouYoung Lee, Séamus Fanning, Roger Stephan, Ben D Tall, Angelika Lehner,

: Cronobacter species are considered an opportunistic group of foodborne pathogenic bacteria capable of causing both intestinal and systemic human disease. This review describes common virulence themes shared among the seven Cronobacter species and describes multiple exoproteins secreted by Cronobacter, many of which are bacterial toxins that may play a ... Read more >>

Microorganisms (Microorganisms)
[2020, 8(2):]

Cited: 0 times

View full text PDF listing >>



Prevalence, Distribution, and Phylogeny of Type Two Toxin-Antitoxin Genes Possessed by Cronobacter Species where C. sakazakii Homologs Follow Sequence Type Lineages.

Samantha Finkelstein, Flavia Negrete, Hyein Jang, Jayanthi Gangiredla, Mark Mammel, Isha R Patel, Hannah R Chase, JungHa Woo, YouYoung Lee, Caroline Z Wang, Leah Weinstein, Ben D Tall, Gopal R Gopinath,

Cronobacter species are a group of foodborne pathogenic bacteria that cause both intestinal and systemic human disease in individuals of all age groups. Little is known about the mechanisms that Cronobacter employ to survive and persist in foods and other environments. Toxin-antitoxin (TA) genes are thought to play a role ... Read more >>

Microorganisms (Microorganisms)
[2019, 7(11):]

Cited: 0 times

View full text PDF listing >>



Advertisement

RNA Sequencing-Based Transcriptional Overview of Xerotolerance in Cronobacter sakazakii SP291.

Shabarinath Srikumar, Yu Cao, Qiongqiong Yan, Koenraad Van Hoorde, Scott Nguyen, Shane Cooney, Gopal R Gopinath, Ben D Tall, Sathesh K Sivasankaran, Angelika Lehner, Roger Stephan, Séamus Fanning,

Cronobacter sakazakii is a xerotolerant neonatal pathogen epidemiologically linked to powdered infant food formula, often resulting in high mortality rates. Here, we used transcriptome sequencing (RNA-seq) to provide transcriptional insights into the survival of C. sakazakii in desiccated conditions. Our RNA-seq data show that about 22% of the total C. ... Read more >>

Appl. Environ. Microbiol. (Applied and environmental microbiology)
[2019, 85(3):]

Cited: 2 times

View full text PDF listing >>



Draft genomes of Cronobacter sakazakii strains isolated from dried spices bring unique insights into the diversity of plant-associated strains.

Hyein Jang, Jungha Woo, Youyoung Lee, Flavia Negrete, Samantha Finkelstein, Hannah R Chase, Nicole Addy, Laura Ewing, Junia Jean Gilles Beaubrun, Isha Patel, Jayanthi Gangiredla, Athmanya Eshwar, Ziad W Jaradat, Kunho Seo, Srikumar Shabarinath, Séamus Fanning, Roger Stephan, Angelika Lehner, Ben D Tall, Gopal R Gopinath,

Cronobacter sakazakii is a Gram-negative opportunistic pathogen that causes life- threatening infantile infections, such as meningitis, septicemia, and necrotizing enterocolitis, as well as pneumonia, septicemia, and urinary tract and wound infections in adults. Here, we report 26 draft genome sequences of C. sakazakii, which were obtained from dried spices from ... Read more >>

Stand Genomic Sci (Standards in genomic sciences)
[2018, 13:35]

Cited: 2 times

View full text PDF listing >>



Analysis of enterotoxigenic Bacillus cereus strains from dried foods using whole genome sequencing, multi-locus sequence analysis and toxin gene prevalence and distribution using endpoint PCR analysis.

Laurenda Carter, Hannah R Chase, Charles M Gieseker, Nicholas R Hasbrouck, Cynthia B Stine, Ashraf Khan, Laura J Ewing-Peeples, Ben D Tall, Gopal R Gopinath,

Bacillus cereus strains were isolated from dried foods, which included international brands of spices from South East Asia, Mexico and India purchased from several retail stores, samples of powdered infant formula (PIF), medicated fish feed and dietary supplements. The genetic diversity of 64 strains from spices and PIF was determined ... Read more >>

Int. J. Food Microbiol. (International journal of food microbiology)
[2018, 284:31-39]

Cited: 0 times

View full text PDF listing >>



Genomic characterization of malonate positive Cronobacter sakazakii serotype O:2, sequence type 64 strains, isolated from clinical, food, and environment samples.

Gopal R Gopinath, Hannah R Chase, Jayanthi Gangiredla, Athmanya Eshwar, Hyein Jang, Isha Patel, Flavia Negrete, Samantha Finkelstein, Eunbi Park, TaeJung Chung, YeonJoo Yoo, JungHa Woo, YouYoung Lee, Jihyeon Park, Hyerim Choi, Seungeun Jeong, Soyoung Jun, Mijeong Kim, Chaeyoon Lee, HyeJin Jeong, Séamus Fanning, Roger Stephan, Carol Iversen, Felix Reich, Günter Klein, Angelika Lehner, Ben D Tall,

Malonate utilization, an important differential trait, well recognized as being possessed by six of the seven Cronobacter species is thought to be largely absent in Cronobacter sakazakii (Csak). The current study provides experimental evidence that confirms the presence of a malonate utilization operon in 24 strains of sequence type (ST) ... Read more >>

Gut Pathog (Gut pathogens)
[2018, 10:11]

Cited: 2 times

View full text PDF listing >>



Whole-Genome Sequences of Cronobacter sakazakii Isolates Obtained from Foods of Plant Origin and Dried-Food Manufacturing Environments.

Hyein Jang, Nicole Addy, Laura Ewing, Junia Jean-Gilles Beaubrun, YouYoung Lee, JungHa Woo, Flavia Negrete, Samantha Finkelstein, Ben D Tall, Angelika Lehner, Athmanya Eshwar, Gopal R Gopinath,

Here, we present draft genome sequences of 29 Cronobacter sakazakii isolates obtained from foods of plant origin and dried-food manufacturing facilities. Assemblies and annotations resulted in genome sizes ranging from 4.3 to 4.5 Mb and 3,977 to 4,256 gene-coding sequences with G+C contents of ∼57.0%. ... Read more >>

Genome Announc (Genome announcements)
[2018, 6(15):]

Cited: 2 times

View full text PDF listing >>



Detection of Salmonella enterica subsp. enterica Serovar Cubana from Naturally Contaminated Chick Feed.

Faiza Benahmed, Hua Wang, Junia Jean-Gilles Beaubrun, Gopal R Gopinath, Chorng-Ming Cheng, Darcy E Hanes, Thomas S Hammack, Mark Rasmussen, Maureen K Davidson,

Because some significant outbreaks of human salmonellosis have been traced to contaminated animal feed, the rapid and efficient detection of Salmonella in feed is essential. However, the current U.S. Food and Drug Administration Bacteriological Analytical Manual (BAM) culture method that uses lactose broth as a preenrichment medium has not reliably ... Read more >>

J. Food Prot. (Journal of food protection)
[2017, 80(11):1815-1820]

Cited: 0 times

View full text PDF listing >>



Comparative Genomic Characterization of the Highly Persistent and Potentially Virulent Cronobacter sakazakii ST83, CC65 Strain H322 and Other ST83 Strains.

Hannah R Chase, Gopal R Gopinath, Athmanya K Eshwar, Andrea Stoller, Claudia Fricker-Feer, Jayanthi Gangiredla, Isha R Patel, Hediye N Cinar, HyeJin Jeong, ChaeYoon Lee, Flavia Negrete, Samantha Finkelstein, Roger Stephan, Ben D Tall, Angelika Lehner,

Cronobacter (C.) sakazakii is an opportunistic pathogen and has been associated with serious infections with high mortality rates predominantly in pre-term, low-birth weight and/or immune compromised neonates and infants. Infections have been epidemiologically linked to consumption of intrinsically and extrinsically contaminated lots of reconstituted powdered infant formula (PIF), thus contamination ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2017, 8:1136]

Cited: 6 times

View full text PDF listing >>



Draft Genome Sequence of Cronobacter sakazakii GP1999, Sequence Type 145, an Epiphytic Isolate Obtained from the Tomato's Rhizoplane/Rhizosphere Continuum.

Hannah R Chase, Leo Eberl, Roger Stephan, HyeJin Jeong, Chaeyoon Lee, Samantha Finkelstein, Flavia Negrete, Jayanthi Gangiredla, Isha Patel, Ben D Tall, Gopal R Gopinath, Angelika Lehner,

We present here the draft genome of Cronobacter sakazakii GP1999, a sequence type 145 strain isolated from the rhizosphere of tomato plants. Assembly and annotation of the genome resulted in a genome of 4,504,670 bp in size, with 4,148 coding sequences, and a GC content of 56.8%. ... Read more >>

Genome Announc (Genome announcements)
[2017, 5(31):]

Cited: 2 times

View full text PDF listing >>



Draft Genome Sequences of Enterotoxigenic Bacillus cereus Strains Obtained from Powdered Infant Formula.

Laurenda Carter, Hannah R Chase, Hyerim Choi, SoYoung Jun, JiHyeon Park, Seungeun Jeong, MiJeong Kim, KyuYoung Han, ChaeYoon Lee, HyeJin Jeong, Samantha Finkelstein, Flavia Negrete, Hediye N Cinar, Ben D Tall, Gopal R Gopinath,

We introduce the draft genome sequences of five enterotoxigenic Bacillus cereus strains: Bc 12, Bc 67, Bc 111, Bc 112, and Bc 113, which were obtained from powdered infant formula. The genome sizes of the strains ranged from 5.5 to 5.8 Mb, and the G+C contents were ~35.2%. ... Read more >>

Genome Announc (Genome announcements)
[2017, 5(8):]

Cited: 0 times

View full text PDF listing >>



Comparative sequence analysis of Cyclospora cayetanensis apicoplast genomes originating from diverse geographical regions.

Hediye Nese Cinar, Yvonne Qvarnstrom, Yuping Wei-Pridgeon, Wen Li, Fernanda S Nascimento, Michael J Arrowood, Helen R Murphy, AhYoung Jang, Eunje Kim, RaeYoung Kim, Alexandre da Silva, Gopal R Gopinath,

Cyclospora cayetanensis is an emerging coccidian parasite that causes endemic and epidemic diarrheal disease called cyclosporiasis, and this infection is associated with consumption of contaminated produce or water in developed and developing regions. Food-borne outbreaks of cyclosporiasis have occurred almost every year in the USA since the 1990s. Investigations of ... Read more >>

Parasit Vectors (Parasites & vectors)
[2016, 9(1):611]

Cited: 7 times

View full text PDF listing >>



Use of a Pan-Genomic DNA Microarray in Determination of the Phylogenetic Relatedness among Cronobacter spp. and Its Use as a Data Mining Tool to Understand Cronobacter Biology.

Ben D Tall, Jayanthi Gangiredla, Christopher J Grim, Isha R Patel, Scott A Jackson, Mark K Mammel, Mahendra H Kothary, Venugopal Sathyamoorthy, Laurenda Carter, Séamus Fanning, Carol Iversen, Franco Pagotto, Roger Stephan, Angelika Lehner, Jeffery Farber, Qiong Q Yan, Gopal R Gopinath,

Cronobacter (previously known as Enterobacter sakazakii) is a genus of Gram-negative, facultatively anaerobic, oxidase-negative, catalase-positive, rod-shaped bacteria of the family Enterobacteriaceae. These organisms cause a variety of illnesses such as meningitis, necrotizing enterocolitis, and septicemia in neonates and infants, and urinary tract, wound, abscesses or surgical site infections, septicemia, and ... Read more >>

Microarrays (Basel) (Microarrays (Basel, Switzerland))
[2017, 6(1):]

Cited: 2 times

View full text PDF listing >>



Analysis and Characterization of Proteins Associated with Outer Membrane Vesicles Secreted by Cronobacter spp.

Mahendra H Kothary, Gopal R Gopinath, Jayanthi Gangiredla, Prasad V Rallabhandi, Lisa M Harrison, Qiong Q Yan, Hannah R Chase, Boram Lee, Eunbi Park, YeonJoo Yoo, Taejung Chung, Samantha B Finkelstein, Flavia J Negrete, Isha R Patel, Laurenda Carter, Venugopal Sathyamoorthy, Séamus Fanning, Ben D Tall,

Little is known about secretion of outer membrane vesicles (OMVs) by Cronobacter. In this study, OMVs isolated from Cronobacter sakazakii, Cronobacter turicensis, and Cronobacter malonaticus were examined by electron microscopy (EM) and their associated outer membrane proteins (OMP) and genes were analyzed by SDS-PAGE, protein sequencing, BLAST, PCR, and DNA ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2017, 8:134]

Cited: 5 times

View full text PDF listing >>



Purification and Characterization of a Rabbit Serum Factor That Kills Listeria Species and Other Foodborne Bacterial Pathogens.

Mahendra H Kothary, Augusto A Franco, Ben D Tall, Gopal R Gopinath, Atin R Datta,

In an in-vitro assay, rabbit serum, but not human serum, killed Listeria monocytogenes, a foodborne pathogen. The aim of our study was to purify and partially characterize this killing factor. Listericidin was purified from rabbit serum by a single-step ion-exchange chromatography with DEAE-Sephadex A-50 and its antimicrobial activity was assessed ... Read more >>

Foodborne Pathog. Dis. (Foodborne pathogens and disease)
[2016, 13(8):441-447]

Cited: 0 times

View full text PDF listing >>



Diverse profiles of N-acyl-homoserine lactones in biofilm forming isolates of Cronobacter sakazakii.

Ben D Tall, Hannah R Chase, Gopal R Gopinath,

Virulence (Virulence)
[2017, 8(3):246-247]

Cited: 1 time

View full text PDF listing >>



Linking Genomo- and Pathotype: Exploiting the Zebrafish Embryo Model to Investigate the Divergent Virulence Potential among Cronobacter spp.

Athmanya K Eshwar, Ben D Tall, Jayanthi Gangiredla, Gopal R Gopinath, Isha R Patel, Stephan C F Neuhauss, Roger Stephan, Angelika Lehner,

Bacteria belonging to the genus Cronobacter have been recognized as causative agents of life-threatening systemic infections primarily in premature, low-birth weight and immune-compromised neonates. Apparently not all Cronobacter species are linked to infantile infections and it has been proposed that virulence varies among strains. Whole genome comparisons and in silico ... Read more >>

PLoS ONE (PloS one)
[2016, 11(6):e0158428]

Cited: 4 times

View full text PDF listing >>



Genome Sequence of Cronobacter sakazakii Serogroup O:4, Sequence Type 4 Strain CDC 2009-03746, Isolated from a Fatal Case of Infantile Meningitis.

Christopher J Grim, Gopal R Gopinath, Karen G Jarvis, Venugopal Sathyamoorthy, Larissa H Trach, Hannah R Chase, Ben D Tall,

We report the draft genome sequence of a Cronobacter sakazakii serogroup O:4, sequence type 4 strain, CDC 2009-03746 (=NM1240=2009-06-01), isolated from a fatal case of infantile meningitis. The draft genome has a size of 4,492,904 bp and a G+C% content of 56.7. ... Read more >>

Genome Announc (Genome announcements)
[2015, 3(3):]

Cited: 2 times

View full text PDF listing >>



Development of a Custom-Designed, Pan Genomic DNA Microarray to Characterize Strain-Level Diversity among Cronobacter spp.

Ben Davies Tall, Jayanthi Gangiredla, Gopal R Gopinath, Qiongqiong Yan, Hannah R Chase, Boram Lee, Seongeun Hwang, Larisa Trach, Eunbi Park, YeonJoo Yoo, TaeJung Chung, Scott A Jackson, Isha R Patel, Venugopal Sathyamoorthy, Monica Pava-Ripoll, Michael L Kotewicz, Laurenda Carter, Carol Iversen, Franco Pagotto, Roger Stephan, Angelika Lehner, Séamus Fanning, Christopher J Grim,

Cronobacter species cause infections in all age groups; however neonates are at highest risk and remain the most susceptible age group for life-threatening invasive disease. The genus contains seven species:Cronobacter sakazakii, Cronobacter malonaticus, Cronobacter turicensis, Cronobacter muytjensii, Cronobacter dublinensis, Cronobacter universalis, and Cronobacter condimenti. Despite an abundance of published genomes ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2015, 3:36]

Cited: 9 times

View full text PDF listing >>



Comparative Genotypic and Phenotypic Analysis of Cronobacter Species Cultured from Four Powdered Infant Formula Production Facilities: Indication of Pathoadaptation along the Food Chain.

Qiongqiong Yan, Juan Wang, Jayanthi Gangiredla, Yu Cao, Marta Martins, Gopal R Gopinath, Roger Stephan, Keith Lampel, Ben D Tall, Séamus Fanning,

Cronobacter species are opportunistic pathogens commonly found in the environment. Among the seven Cronobacter species, Cronobacter sakazakii sequence type 4 (ST-4) is predominantly associated with recorded cases of infantile meningitis. This study reports on a 26-month powdered infant formula (PIF) surveillance program in four production facilities located in distinct geographic ... Read more >>

Appl. Environ. Microbiol. (Applied and environmental microbiology)
[2015, 81(13):4388-4402]

Cited: 9 times

View full text PDF listing >>



Draft Genome Sequences of Streptococcus bovis Strains ATCC 33317 and JB1.

Faiza H Benahmed, Gopal R Gopinath, Heather Harbottle, Michael A Cotta, Yan Luo, Carol Henderson, Plona Teri, Daniel Soppet, Mark Rasmussen, Terence R Whitehead, Maureen Davidson,

We report the draft genome sequences of Streptococcus bovis strain ATCC 33317 (CVM42251) isolated from cow dung and strain JB1 (CVM42252) isolated from a cow rumen in 1977. The strains were sequenced using the Genome Sequencer FLX 454 system. The genome sizes are approximately 2 Mb and 2.2 Mb, respectively. ... Read more >>

Genome Announc (Genome announcements)
[2014, 2(5):]

Cited: 0 times

View full text PDF listing >>



Genome Sequence of Enterobacter turicensis Strain 610/05 (LMG 23731), Isolated from Fruit Powder.

Roger Stephan, Christopher J Grim, Gopal R Gopinath, Mark K Mammel, Venugopal Sathyamoorthy, Larisa H Trach, Hannah R Chase, Séamus Fanning, Ben D Tall,

We report the draft genome sequence of Enterobacter turicensis strain 610/05 (LMG 23731), isolated from fruit powder. The draft genome has a size of 4,182,790 bp and a G+C% content of 58.0. ... Read more >>

Genome Announc (Genome announcements)
[2013, 1(6):]

Cited: 2 times

View full text PDF listing >>



Re-examination of the taxonomic status of Enterobacter helveticus, Enterobacter pulveris and Enterobacter turicensis as members of the genus Cronobacter and their reclassification in the genera Franconibacter gen. nov. and Siccibacter gen. nov. as Franconibacter helveticus comb. nov., Franconibacter pulveris comb. nov. and Siccibacter turicensis comb. nov., respectively.

Roger Stephan, Christopher J Grim, Gopal R Gopinath, Mark K Mammel, Venugopal Sathyamoorthy, Larisa H Trach, Hannah R Chase, Séamus Fanning, Ben D Tall,

Recently, a taxonomical re-evaluation of the genus Enterobacter, based on multi-locus sequence typing (MLST) analysis, has led to the proposal that the species Enterobacter pulveris, Enterobacter helveticus and Enterobacter turicensis should be reclassified as novel species of the genus Cronobacter. In the present work, new genome-scale analyses, including average nucleotide ... Read more >>

Int. J. Syst. Evol. Microbiol. (International journal of systematic and evolutionary microbiology)
[2014, 64(Pt 10):3402-3410]

Cited: 46 times

View full text PDF listing >>



Genome Sequence of an Enterobacter helveticus Strain, 1159/04 (LMG 23733), Isolated from Fruit Powder.

Christopher J Grim, Gopal R Gopinath, Mark K Mammel, Venugopal Sathyamoorthy, Larisa H Trach, Hannah R Chase, Ben D Tall, Séamus Fanning, Roger Stephan,

We report the draft genome sequence of Enterobacter helveticus strain LMG 23733, isolated from fruit powder. The draft genome assembly for E. helveticus strain LMG 23733 has a size of 4,635,476 bp and a G+C content of 55.9%. ... Read more >>

Genome Announc (Genome announcements)
[2013, 1(6):]

Cited: 2 times

View full text PDF listing >>



Complete genome sequence and phenotype microarray analysis of Cronobacter sakazakii SP291: a persistent isolate cultured from a powdered infant formula production facility.

Qiongqiong Yan, Karen A Power, Shane Cooney, Edward Fox, Gopal R Gopinath, Christopher J Grim, Ben D Tall, Matthew P McCusker, Séamus Fanning,

Outbreaks of human infection linked to the powdered infant formula (PIF) food chain and associated with the bacterium Cronobacter, are of concern to public health. These bacteria are regarded as opportunistic pathogens linked to life-threatening infections predominantly in neonates, with an under developed immune system. Monitoring the microbiological ecology of ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2013, 4:256]

Cited: 15 times

View full text PDF listing >>



Advertisement

Disclaimer
1.6206 s